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Items: 1 to 50 of 475

1.

Developing a Conceptual Framework for Environmental Health Tracking in Victoria, Australia.

Edokpolo B, Allaz-Barnett N, Irwin C, Issa J, Curtis P, Green B, Hanigan I, Dennekamp M.

Int J Environ Res Public Health. 2019 May 17;16(10). pii: E1748. doi: 10.3390/ijerph16101748.

2.

Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial.

Garcia-Manero G, Roboz G, Walsh K, Kantarjian H, Ritchie E, Kropf P, O'Connell C, Tibes R, Lunin S, Rosenblat T, Yee K, Stock W, Griffiths E, Mace J, Podoltsev N, Berdeja J, Jabbour E, Issa JJ, Hao Y, Keer HN, Azab M, Savona MR.

Lancet Haematol. 2019 Jun;6(6):e317-e327. doi: 10.1016/S2352-3026(19)30029-8. Epub 2019 May 3.

PMID:
31060979
3.

Undernutrition impairs the quality of growth plate and trabecular and cortical bones in growing rats1.

Guedes PMSG, Zamarioli A, Botega II, Silva RABD, Issa JPM, Butezloff MM, Sousa YTCS, Ximenez JPB, Volpon JB.

Acta Cir Bras. 2019 Mar 18;34(3):e201900301. doi: 10.1590/s0102-865020190030000001.

4.

Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate.

Pope JL, Yang Y, Newsome RC, Sun W, Sun X, Ukhanova M, Neu J, Issa JP, Mai V, Jobin C.

Sci Rep. 2019 Mar 4;9(1):3380. doi: 10.1038/s41598-019-39887-8.

5.

Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture1.

Botega II, Zamarioli A, Guedes PMSG, Silva RABD, Issa JPM, Butezloff MM, Sousa YTCS, Ximenez JPB, Volpon JB.

Acta Cir Bras. 2019 Feb 14;34(1):e20190010000002. doi: 10.1590/s0102-865020190010000002.

6.

Whole-Organ Genomic Characterization of Mucosal Field Effects Initiating Bladder Carcinogenesis.

Majewski T, Yao H, Bondaruk J, Chung W, Lee S, Lee JG, Zhang S, Cogdell D, Yang G, Choi W, Dinney C, Grossman HB, Logothetis C, Scherer SE, Guo CC, Zhang L, Wei P, Weinstein JN, Issa JP, Baggerly K, McConkey DJ, Czerniak B.

Cell Rep. 2019 Feb 19;26(8):2241-2256.e4. doi: 10.1016/j.celrep.2019.01.095.

7.

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis.

Tao Y, Kang B, Petkovich DA, Bhandari YR, In J, Stein-O'Brien G, Kong X, Xie W, Zachos N, Maegawa S, Vaidya H, Brown S, Chiu Yen RW, Shao X, Thakor J, Lu Z, Cai Y, Zhang Y, Mallona I, Peinado MA, Zahnow CA, Ahuja N, Fertig E, Issa JP, Baylin SB, Easwaran H.

Cancer Cell. 2019 Feb 11;35(2):315-328.e6. doi: 10.1016/j.ccell.2019.01.005.

PMID:
30753828
8.

NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis.

Taira TM, Lima V, Prado DS, Silva TA, Issa JPM, da Silva LAB, Zamboni DS, Cunha FQ, Fukada SY.

J Dent Res. 2019 Apr;98(4):476-484. doi: 10.1177/0022034518820289. Epub 2019 Jan 25.

PMID:
30681895
9.

Effectiveness of rhBMP-2 association to autogenous, allogeneic, and heterologous bone grafts.

Gonzaga MG, Dos Santos Kotake BG, de Figueiredo FAT, Feldman S, Ervolino E, Dos Santos MCG, Issa JPM.

Microsc Res Tech. 2019 Jun;82(6):689-695. doi: 10.1002/jemt.23215. Epub 2019 Jan 14.

PMID:
30637849
10.

Application of Autologous Platelet-Rich Plasma on Tooth Extraction Site Prevents Occurence of Medication-Related Osteonecrosis of the Jaws in Rats.

Toro LF, de Mello-Neto JM, Santos FFVD, Ferreira LC, Statkievicz C, Cintra LTÂ, Issa JPM, Dornelles RCM, de Almeida JM, Nagata MJH, Garcia VG, Theodoro LH, Casatti CA, Ervolino E.

Sci Rep. 2019 Jan 10;9(1):22. doi: 10.1038/s41598-018-37063-y.

11.

A miniature multi-contrast microscope for functional imaging in freely behaving animals.

Senarathna J, Yu H, Deng C, Zou AL, Issa JB, Hadjiabadi DH, Gil S, Wang Q, Tyler BM, Thakor NV, Pathak AP.

Nat Commun. 2019 Jan 9;10(1):99. doi: 10.1038/s41467-018-07926-z.

12.

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.

Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, Bhanu NV, Simithy J, Patel B, Huang J, Raynal NJ, Garcia BA, Jacobson MA, Kadoch C, Merali S, Zhang Y, Childers W, Abou-Gharbia M, Karanicolas J, Baylin SB, Zahnow CA, Jelinek J, Graña X, Issa JJ.

Cell. 2018 Nov 15;175(5):1244-1258.e26. doi: 10.1016/j.cell.2018.09.051. Epub 2018 Oct 25.

PMID:
30454645
13.

Naringenin mitigates titanium dioxide (TiO2)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB.

Manchope MF, Artero NA, Fattori V, Mizokami SS, Pitol DL, Issa JPM, Fukada SY, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA Jr.

Inflamm Res. 2018 Dec;67(11-12):997-1012. doi: 10.1007/s00011-018-1195-y. Epub 2018 Oct 28.

PMID:
30370484
14.

Antimicrobial photodynamic therapy improves the alveolar repair process and prevents the occurrence of osteonecrosis of the jaws after tooth extraction in senile rats treated with zoledronate.

Ervolino E, Statkievicz C, Toro LF, de Mello-Neto JM, Cavazana TP, Issa JPM, Dornelles RCM, de Almeida JM, Nagata MJH, Okamoto R, Casatti CA, Garcia VG, Theodoro LH.

Bone. 2019 Mar;120:101-113. doi: 10.1016/j.bone.2018.10.014. Epub 2018 Oct 16.

PMID:
30339908
15.

Homeostatic Control of Spontaneous Activity in the Developing Auditory System.

Babola TA, Li S, Gribizis A, Lee BJ, Issa JB, Wang HC, Crair MC, Bergles DE.

Neuron. 2018 Aug 8;99(3):511-524.e5. doi: 10.1016/j.neuron.2018.07.004. Epub 2018 Aug 1.

PMID:
30077356
16.

TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer.

Good CR, Panjarian S, Kelly AD, Madzo J, Patel B, Jelinek J, Issa JJ.

Cancer Res. 2018 Aug 1;78(15):4126-4137. doi: 10.1158/0008-5472.CAN-17-2082. Epub 2018 Jun 11.

PMID:
29891505
17.

[Surgery is unlikely to be enough for a patient to stop smoking 24h prior to hospital admission].

Marinho IM, Carmona MJC, Benseñor FEM, Hertel JM, Moraes MFB, Santos PCJL, Vane MF, Issa JS.

Rev Bras Anestesiol. 2018 Jul - Aug;68(4):344-350. doi: 10.1016/j.bjan.2017.12.007. Epub 2018 Jun 7. Portuguese.

18.

Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion.

Garriga J, Laumet G, Chen SR, Zhang Y, Madzo J, Issa JJ, Pan HL, Jelinek J.

J Neurosci. 2018 Jul 4;38(27):6090-6101. doi: 10.1523/JNEUROSCI.2616-17.2018. Epub 2018 Jun 6.

19.

MMPs are Involved in Osteoporosis and are Correlated with Cardiovascular Diseases.

Azevedo A, Prado AF, Feldman S, de Figueiredo FAT, Dos Santos MCG, Issa JPM.

Curr Pharm Des. 2018;24(16):1801-1810. doi: 10.2174/1381612824666180604112925.

PMID:
29865998
20.

Photomodulation multiple sessions as a promising preventive therapy for medication-related osteonecrosis of the jaws after tooth extraction in rats.

Statkievicz C, Toro LF, de Mello-Neto JM, de Sá DP, Casatti CA, Issa JPM, Cintra LTA, de Almeida JM, Nagata MJH, Garcia VG, Theodoro LH, Ervolino E.

J Photochem Photobiol B. 2018 Jul;184:7-17. doi: 10.1016/j.jphotobiol.2018.05.004. Epub 2018 May 9.

PMID:
29777942
21.

Demethylator phenotypes in acute myeloid leukemia.

Kelly AD, Madzo J, Madireddi P, Kropf P, Good CR, Jelinek J, Issa JJ.

Leukemia. 2018 Oct;32(10):2178-2188. doi: 10.1038/s41375-018-0084-2. Epub 2018 Mar 7.

22.

Effects of high-impact exercise on the physical properties of bones of ovariectomized rats fed to a high-protein diet.

Shimano RC, Yanagihara GR, Macedo AP, Yamanaka JS, Shimano AC, Tavares JMRS, Issa JPM.

Scand J Med Sci Sports. 2018 May;28(5):1523-1531. doi: 10.1111/sms.13058. Epub 2018 Feb 8.

PMID:
29345841
23.

Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity.

He S, Liu Y, Meng L, Sun H, Wang Y, Ji Y, Purushe J, Chen P, Li C, Madzo J, Issa JP, Soboloff J, Reshef R, Moore B, Gattinoni L, Zhang Y.

Nat Commun. 2017 Dec 14;8(1):2125. doi: 10.1038/s41467-017-02187-8.

24.

Nandrolone decanoate appears to increase bone callus formation in young adult rats after a complete femoral fracture.

Guimarães APFGM, Butezloff MM, Zamarioli A, Issa JPM, Volpon JB.

Acta Cir Bras. 2017 Nov;32(11):924-934. doi: 10.1590/s0102-865020170110000004.

25.

Digital Restriction Enzyme Analysis of Methylation (DREAM).

Jelinek J, Lee JT, Cesaroni M, Madzo J, Liang S, Lu Y, Issa JJ.

Methods Mol Biol. 2018;1708:247-265. doi: 10.1007/978-1-4939-7481-8_13.

PMID:
29224148
26.

Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia.

Roboz GJ, Kantarjian HM, Yee KWL, Kropf PL, O'Connell CL, Griffiths EA, Stock W, Daver NG, Jabbour E, Ritchie EK, Walsh KJ, Rizzieri D, Lunin SD, Curio T, Chung W, Hao Y, Lowder JN, Azab M, Issa JJ.

Cancer. 2018 Jan 15;124(2):325-334. doi: 10.1002/cncr.31138. Epub 2017 Dec 6.

27.

The flavonoid quercetin inhibits titanium dioxide (TiO2)-induced chronic arthritis in mice.

Borghi SM, Mizokami SS, Pinho-Ribeiro FA, Fattori V, Crespigio J, Clemente-Napimoga JT, Napimoga MH, Pitol DL, Issa JPM, Fukada SY, Casagrande R, Verri WA Jr.

J Nutr Biochem. 2018 Mar;53:81-95. doi: 10.1016/j.jnutbio.2017.10.010. Epub 2017 Nov 5.

PMID:
29197723
28.

Smoking cessation leads to changes in survivin expression in oral mucosa.

Lima CF, Crastechini E, Dos Santos NC, Prado Ribeiro AC, Brandão TB, Castro FCF, Issa JS, Almeida JD.

J Oral Pathol Med. 2018 Mar;47(3):293-298. doi: 10.1111/jop.12664. Epub 2017 Dec 7.

PMID:
29160903
29.

Bone repair of critical-sized defects in Wistar rats treated with autogenic, allogenic or xenogenic bone grafts alone or in combination with natural latex fraction F1.

Santos Kotake BG, Gonzaga MG, Coutinho-Netto J, Ervolino E, de Figueiredo FAT, Issa JPM.

Biomed Mater. 2018 Feb 8;13(2):025022. doi: 10.1088/1748-605X/aa9504.

PMID:
29053112
30.

Epigenetics and Precision Oncology.

Werner RJ, Kelly AD, Issa JJ.

Cancer J. 2017 Sep/Oct;23(5):262-269. doi: 10.1097/PPO.0000000000000281. Review.

31.

Introduction: Cancer as an Epigenetic Disease.

Issa JJ.

Cancer J. 2017 Sep/Oct;23(5):255-256. doi: 10.1097/PPO.0000000000000285. No abstract available.

32.

Caloric restriction delays age-related methylation drift.

Maegawa S, Lu Y, Tahara T, Lee JT, Madzo J, Liang S, Jelinek J, Colman RJ, Issa JJ.

Nat Commun. 2017 Sep 14;8(1):539. doi: 10.1038/s41467-017-00607-3.

33.

Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: phase 2 results from a multicentre, randomised, phase 1/2 trial.

Kantarjian HM, Roboz GJ, Kropf PL, Yee KWL, O'Connell CL, Tibes R, Walsh KJ, Podoltsev NA, Griffiths EA, Jabbour E, Garcia-Manero G, Rizzieri D, Stock W, Savona MR, Rosenblat TL, Berdeja JG, Ravandi F, Rock EP, Hao Y, Azab M, Issa JJ.

Lancet Oncol. 2017 Oct;18(10):1317-1326. doi: 10.1016/S1470-2045(17)30576-4. Epub 2017 Aug 24.

34.

Roadmap for investigating epigenome deregulation and environmental origins of cancer.

Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, Duthie SJ, Fry R, Issa JP, Kellermayer R, Koturbash I, Kondo Y, Lepeule J, Lima SCS, Marsit CJ, Rakyan V, Saffery R, Taylor JA, Teschendorff AE, Ushijima T, Vineis P, Walker CL, Waterland RA, Wiemels J, Ambatipudi S, Degli Esposti D, Hernandez-Vargas H.

Int J Cancer. 2018 Mar 1;142(5):874-882. doi: 10.1002/ijc.31014. Epub 2017 Sep 13. Review.

35.

Atualização da Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose – 2017.

Faludi AA, Izar MCO, Saraiva JFK, Chacra APM, Bianco HT, Afiune A Neto, Bertolami A, Pereira AC, Lottenberg AM, Sposito AC, Chagas ACP, Casella A Filho, Simão AF, Alencar AC Filho, Caramelli B, Magalhães CC, Negrão CE, Ferreira CEDS, Scherr C, Feio CMA, Kovacs C, Araújo DB, Magnoni D, Calderaro D, Gualandro DM, Mello EP Junior, Alexandre ERG, Sato EI, Moriguchi EH, Rached FH, Santos FCD, Cesena FHY, Fonseca FAH, Fonseca HARD, Xavier HT, Mota ICP, Giuliano ICB, Issa JS, Diament J, Pesquero JB, Santos JED, Faria JR Neto, Melo JX Filho, Kato JT, Torres KP, Bertolami MC, Assad MHV, Miname MH, Scartezini M, Forti NA, Coelho OR, Maranhão RC, Santos RDD Filho, Alves RJ, Cassani RL, Betti RTB, Carvalho T, Martinez TLDR, Giraldez VZR, Salgado W Filho.

Arq Bras Cardiol. 2017 Jul;109(2 Supl 1):1-76. doi: 10.5935/abc.20170121. Portuguese. No abstract available. Erratum in: Arq Bras Cardiol. 2017 Nov;109 (5):499.

36.

Low-intensity laser therapy efficacy evaluation in mice subjected to acute arthritis condition.

Trawitzki BF, Lilge L, de Figueiredo FAT, Macedo AP, Issa JPM.

J Photochem Photobiol B. 2017 Sep;174:126-132. doi: 10.1016/j.jphotobiol.2017.07.028. Epub 2017 Jul 26.

PMID:
28772237
37.

Low-intensity laser therapy efficacy evaluation in FVB mice subjected to acute and chronic arthritis.

Issa JPM, Trawitzki BF, Ervolino E, Macedo AP, Lilge L.

Lasers Med Sci. 2017 Aug;32(6):1269-1277. doi: 10.1007/s10103-017-2235-5. Epub 2017 May 30.

PMID:
28560473
38.

A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer.

Good CR, Madzo J, Patel B, Maegawa S, Engel N, Jelinek J, Issa JJ.

Nucleic Acids Res. 2017 Aug 21;45(14):8269-8281. doi: 10.1093/nar/gkx435.

39.

A high-fat diet can affect bone healing in growing rats.

Yamanaka JS, Yanagihara GR, Carlos BL, Ramos J, Brancaleon BB, Macedo AP, Issa JPM, Shimano AC.

J Bone Miner Metab. 2018 May;36(3):255-263. doi: 10.1007/s00774-017-0837-4. Epub 2017 May 17.

PMID:
28516218
40.

Preclinical study of a cost-effective photodynamic therapy protocol for treating oral candidoses.

da Silva NR, Ribeiro DG, Issa JPM, Bonfá K, Menezes MS, Oliveira VC, de Souza RF.

Lasers Med Sci. 2017 Aug;32(6):1253-1260. doi: 10.1007/s10103-017-2228-4. Epub 2017 May 15.

PMID:
28508242
41.

* Bone Regeneration Mediated by a Bioactive and Biodegradable Extracellular Matrix-Like Hydrogel Based on Elastin-Like Recombinamers.

Coletta DJ, Ibáñez-Fonseca A, Missana LR, Jammal MV, Vitelli EJ, Aimone M, Zabalza F, Issa JPM, Alonso M, Rodríguez-Cabello JC, Feldman S.

Tissue Eng Part A. 2017 Dec;23(23-24):1361-1371. doi: 10.1089/ten.TEA.2017.0047. Epub 2017 Aug 22.

PMID:
28457199
42.

The promise of epigenetic therapy: reprogramming the cancer epigenome.

Kelly AD, Issa JJ.

Curr Opin Genet Dev. 2017 Feb;42:68-77. doi: 10.1016/j.gde.2017.03.015. Epub 2017 Apr 14. Review.

PMID:
28412585
43.

DNA Hypomethylating Drugs in Cancer Therapy.

Sato T, Issa JJ, Kropf P.

Cold Spring Harb Perspect Med. 2017 May 1;7(5). pii: a026948. doi: 10.1101/cshperspect.a026948. Review.

44.

Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium.

Toth R, Scherer D, Kelemen LE, Risch A, Hazra A, Balavarca Y, Issa JJ, Moreno V, Eeles RA, Ogino S, Wu X, Ye Y, Hung RJ, Goode EL, Ulrich CM; OCAC, CORECT, TRICL, ELLIPSE, DRIVE, and GAME-ON consortia.

Cancer Epidemiol Biomarkers Prev. 2017 Jun;26(6):816-825. doi: 10.1158/1055-9965.EPI-16-0728. Epub 2017 Jan 23.

45.

A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome.

Kelly AD, Kroeger H, Yamazaki J, Taby R, Neumann F, Yu S, Lee JT, Patel B, Li Y, He R, Liang S, Lu Y, Cesaroni M, Pierce SA, Kornblau SM, Bueso-Ramos CE, Ravandi F, Kantarjian HM, Jelinek J, Issa JP.

Leukemia. 2017 Oct;31(10):2011-2019. doi: 10.1038/leu.2017.12. Epub 2017 Jan 11.

46.

Multiscale mapping of frequency sweep rate in mouse auditory cortex.

Issa JB, Haeffele BD, Young ED, Yue DT.

Hear Res. 2017 Feb;344:207-222. doi: 10.1016/j.heares.2016.11.018. Epub 2016 Dec 21.

47.

Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome.

Raynal NJ, Da Costa EM, Lee JT, Gharibyan V, Ahmed S, Zhang H, Sato T, Malouf GG, Issa JJ.

Mol Cancer Ther. 2017 Feb;16(2):397-407. doi: 10.1158/1535-7163.MCT-16-0588. Epub 2016 Dec 15.

48.

Transcriptional Selectivity of Epigenetic Therapy in Cancer.

Sato T, Cesaroni M, Chung W, Panjarian S, Tran A, Madzo J, Okamoto Y, Zhang H, Chen X, Jelinek J, Issa JJ.

Cancer Res. 2017 Jan 15;77(2):470-481. doi: 10.1158/0008-5472.CAN-16-0834. Epub 2016 Nov 22.

49.

Comparison of RNA Extraction Methods for Molecular Analysis of Oral Cytology.

Alves MG, Pérez-Sayáns M, Padín-Iruegas ME, Reboiras-López MD, Suarez-Peńaranda JM, López-López R, Carta CF, Issa JS, García-García A, Almeida JD.

Acta Stomatol Croat. 2016 Jun;50(2):108-115.

50.

Repair genes expression profile of MLH1, MSH2 and ATM in the normal oral mucosa of chronic smokers.

Alves MG, Carta CF, de Barros PP, Issa JS, Nunes FD, Almeida JD.

Arch Oral Biol. 2017 Jan;73:60-65. doi: 10.1016/j.archoralbio.2016.09.006. Epub 2016 Sep 16.

PMID:
27693945

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