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Items: 1 to 50 of 148

1.

Epidural Spinal Mass as the Presenting Feature of B-Acute Lymphoblastic Leukemia in a Young Child.

Chapman S, Li J, Almiski M, Moffat H, Israels SJ.

J Pediatr Hematol Oncol. 2019 Oct 4. doi: 10.1097/MPH.0000000000001609. [Epub ahead of print]

PMID:
31593007
2.

Aberrant splicing contributes to severe α-spectrin-linked congenital hemolytic anemia.

Gallagher PG, Maksimova Y, Lezon-Geyda K, Newburger PE, Medeiros D, Hanson RD, Rothman J, Israels S, Wall DA, Sidonio RF Jr, Sieff C, Gowans LK, Mittal N, Rivera-Santiago R, Speicher DW, Baserga SJ, Schulz VP.

J Clin Invest. 2019 Apr 30;129(7):2878-2887. doi: 10.1172/JCI127195.

3.

Comparison of light transmission aggregometry and multiple electrode aggregometry for the evaluation of patients with mucocutaneous bleeding.

Sun P, McMillan-Ward E, Mian R, Israels SJ.

Int J Lab Hematol. 2019 Feb;41(1):133-140. doi: 10.1111/ijlh.12937. Epub 2018 Oct 25.

PMID:
30358923
4.

Analysis of procoagulant phosphatidylserine-exposing platelets by imaging flow cytometry.

Reddy EC, Wang H, Christensen H, McMillan-Ward E, Israels SJ, Bang KWA, Rand ML.

Res Pract Thromb Haemost. 2018 Aug 23;2(4):736-750. doi: 10.1002/rth2.12144. eCollection 2018 Oct.

5.

Impact of Vertebral Fractures and Glucocorticoid Exposure on Height Deficits in Children During Treatment of Leukemia.

Ma J, Siminoski K, Alos N, Halton J, Ho J, Cummings EA, Shenouda N, Matzinger MA, Lentle B, Jaremko JL, Wilson B, Stephure D, Stein R, Sbrocchi AM, Rodd C, Lewis VA, Laverdière C, Israels S, Grant RM, Fernandez CV, Dix DB, Couch R, Cairney E, Barr R, Atkinson S, Abish S, Moher D, Rauch F, Ward LM; Canadian STOPP Consortium.

J Clin Endocrinol Metab. 2019 Feb 1;104(2):213-222. doi: 10.1210/jc.2018-01083.

6.

Laboratory diagnosis of inherited platelet function disorders.

Rand ML, Reddy EC, Israels SJ.

Transfus Apher Sci. 2018 Aug;57(4):485-493. doi: 10.1016/j.transci.2018.07.009. Epub 2018 Jul 24. Review.

PMID:
30054199
7.

Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes.

Wong JC, Bryant V, Lamprecht T, Ma J, Walsh M, Schwartz J, Del Pilar Alzamora M, Mullighan CG, Loh ML, Ribeiro R, Downing JR, Carroll WL, Davis J, Gold S, Rogers PC, Israels S, Yanofsky R, Shannon K, Klco JM.

JCI Insight. 2018 Jul 26;3(14). pii: 121086. doi: 10.1172/jci.insight.121086. eCollection 2018 Jul 26.

8.

Bone Morbidity and Recovery in Children With Acute Lymphoblastic Leukemia: Results of a Six-Year Prospective Cohort Study.

Ward LM, Ma J, Lang B, Ho J, Alos N, Matzinger MA, Shenouda N, Lentle B, Jaremko JL, Wilson B, Stephure D, Stein R, Sbrocchi AM, Rodd C, Lewis V, Israels S, Grant RM, Fernandez CV, Dix DB, Cummings EA, Couch R, Cairney E, Barr R, Abish S, Atkinson SA, Hay J, Rauch F, Moher D, Siminoski K, Halton J; Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) Consortium.

J Bone Miner Res. 2018 Aug;33(8):1435-1443. doi: 10.1002/jbmr.3447. Epub 2018 May 22.

9.

Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort.

Feldman BM, Rivard GE, Babyn P, Wu JKM, Steele M, Poon MC, Card RT, Israels SJ, Laferriere N, Gill K, Chan AK, Carcao M, Klaassen RJ, Cloutier S, Price VE, Dover S, Blanchette VS.

Lancet Haematol. 2018 Jun;5(6):e252-e260. doi: 10.1016/S2352-3026(18)30048-6. Epub 2018 May 3.

PMID:
29731369
10.

Discordant von Willebrand factor (VWF) activity in patients with VWF p.Gly1324Ser confirmed in vitro.

Bowman M, Rimmer E, Houston DS, Israels SJ, James P.

Haemophilia. 2018 Mar;24(2):e57-e59. doi: 10.1111/hae.13401. Epub 2018 Jan 17. No abstract available.

PMID:
29341351
11.

Age at cancer diagnosis, non-O blood group and asparaginase therapy are independently associated with deep venous thrombosis in pediatric oncology patients: A risk model.

Spavor M, Halton J, Dietrich K, Israels S, Shereck E, Yong J, Yasui Y, Mitchell LG.

Thromb Res. 2016 Aug;144:27-31. doi: 10.1016/j.thromres.2016.05.015. Epub 2016 May 18.

PMID:
27270219
12.

Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia.

Chen Y, Henson ES, Xiao W, Huang D, McMillan-Ward EM, Israels SJ, Gibson SB.

Autophagy. 2016 Jun 2;12(6):1029-46. doi: 10.1080/15548627.2016.1164357. Epub 2016 May 11.

13.

Incident Vertebral Fractures in Children With Leukemia During the Four Years Following Diagnosis.

Cummings EA, Ma J, Fernandez CV, Halton J, Alos N, Miettunen PM, Jaremko JL, Ho J, Shenouda N, Matzinger MA, Lentle B, Stephure D, Stein R, Sbrocchi AM, Rodd C, Lang B, Israels S, Grant RM, Couch R, Barr R, Hay J, Rauch F, Siminoski K, Ward LM; Canadian STOPP Consortium (National Pediatric Bone Health Working Group).

J Clin Endocrinol Metab. 2015 Sep;100(9):3408-17. doi: 10.1210/JC.2015-2176. Epub 2015 Jul 14.

14.

Experience with central venous access devices (CVADs) in the Canadian hemophilia primary prophylaxis study (CHPS).

Langley AR, Stain AM, Chan A, McLimont M, Chait S, Wu J, Poon MC, Card R, Israels SJ, Laferriere N, Klaassen RJ, Rivard GE, Cloutier S, Hawes S, Feldman B, Blanchette V.

Haemophilia. 2015 Jul;21(4):469-76. doi: 10.1111/hae.12713.

PMID:
26104147
15.

Geographical variation in the incidence of childhood leukaemia in Manitoba.

Torabi M, Singh H, Galloway K, Israels SJ.

J Paediatr Child Health. 2015 Nov;51(11):1121-6. doi: 10.1111/jpc.12930. Epub 2015 Jun 3.

PMID:
26041118
16.

Laboratory testing for platelet function disorders.

Israels SJ.

Int J Lab Hematol. 2015 May;37 Suppl 1:18-24. doi: 10.1111/ijlh.12346. Review.

PMID:
25976956
17.

Increased requirement for central venous catheter replacement in paediatric oncology patients with deep venous thrombosis: a multicentre study.

Kulkarni K, Halton J, Spavor M, Israels SJ, Abish S, Yong J, Yasui Y, Mitchell LG.

Thromb Haemost. 2015 Feb;113(2):434-5. doi: 10.1160/TH14-07-0626. Epub 2014 Oct 2. No abstract available.

PMID:
25273363
18.

Markers of platelet activation are increased in adolescents with type 2 diabetes.

Israels SJ, McNicol A, Dean HJ, Cognasse F, Sellers EA.

Diabetes Care. 2014 Aug;37(8):2400-3. doi: 10.2337/dc13-2718. Epub 2014 May 30.

PMID:
24879840
19.

von Willebrand disease and platelet disorders.

Favaloro EJ, Bodó I, Israels SJ, Brown SA.

Haemophilia. 2014 May;20 Suppl 4:59-64. doi: 10.1111/hae.12414. Review.

PMID:
24762277
20.

Cancer incidence, morbidity, and survival in Canadian first nation children: a Manitoba population-based study from the cancer in young people in Canada (CYP-C) registry.

Stammers DM, Israels SJ, Lambert PJ, Cuvelier GD.

Pediatr Blood Cancer. 2014 Dec;61(12):2164-9. doi: 10.1002/pbc.25005. Epub 2014 Feb 26.

PMID:
24616082
21.

Intracranial atypical teratoid/rhabdoid tumor presenting as an axillary mass: a case report and review of literature.

Bush JW, Hancock B, Israels SJ, Ellison DW, Stefanovici C, Krawitz S.

Pediatr Dev Pathol. 2014 Mar-Apr;17(2):122-5. doi: 10.2350/14-01-1427-CR.1. Epub 2014 Feb 20. Review.

PMID:
24555876
22.

Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study.

Hilliard P, Zourikian N, Blanchette V, Chan A, Elliott B, Israels SJ, Nilson J, Poon MC, Laferriere N, Van Neste C, Jarock C, Wu J, McLimont M, Feldman B.

J Thromb Haemost. 2013 Mar;11(3):460-6. doi: 10.1111/jth.12113.

23.

What we have learned from inherited platelet disorders.

Israels SJ, Rand ML.

Pediatr Blood Cancer. 2013;60 Suppl 1:S2-7. doi: 10.1002/pbc.24345. Epub 2012 Oct 25. Review.

PMID:
23109117
24.

Magnetic resonance imaging and joint outcomes in boys with severe hemophilia A treated with tailored primary prophylaxis in Canada.

Kraft J, Blanchette V, Babyn P, Feldman B, Cloutier S, Israels S, Pai M, Rivard GE, Gomer S, McLimont M, Moineddin R, Doria AS.

J Thromb Haemost. 2012 Dec;10(12):2494-502. doi: 10.1111/jth.12025.

25.

The development of bone mineral lateralization in the arms.

Siminoski K, Lee KC, Abish S, Alos N, Bell L, Blydt-Hansen T, Couch R, Cummings EA, Ellsworth J, Feber J, Fernandez CV, Halton J, Huber AM, Israels S, Jurencak R, Lang B, Laverdière C, LeBlanc C, Lewis V, Midgley J, Miettunen PM, Oen K, Phan V, Pinsk M, Rauch F, Rodd C, Roth J, Saint-Cyr C, Scuccimarri R, Stephure D, Taback S, Wilson B, Ward LM; Canadian STOPP Consortium National Pediatric Bone Health Working Group.

Osteoporos Int. 2013 Mar;24(3):999-1006. doi: 10.1007/s00198-012-2054-2. Epub 2012 Jun 29.

26.

High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy.

Alos N, Grant RM, Ramsay T, Halton J, Cummings EA, Miettunen PM, Abish S, Atkinson S, Barr R, Cabral DA, Cairney E, Couch R, Dix DB, Fernandez CV, Hay J, Israels S, Laverdière C, Lentle B, Lewis V, Matzinger M, Rodd C, Shenouda N, Stein R, Stephure D, Taback S, Wilson B, Williams K, Rauch F, Siminoski K, Ward LM.

J Clin Oncol. 2012 Aug 1;30(22):2760-7. doi: 10.1200/JCO.2011.40.4830. Epub 2012 Jun 25.

27.

A Dutch Fanconi Anemia FANCC Founder Mutation in Canadian Manitoba Mennonites.

de Vries Y, Lwiwski N, Levitus M, Kuyt B, Israels SJ, Arwert F, Zwaan M, Greenberg CR, Alter BP, Joenje H, Meijers-Heijboer H.

Anemia. 2012;2012:865170. doi: 10.1155/2012/865170. Epub 2012 Jun 4.

28.

Unintended benefit of anabolic steroid use in hemophilia B leiden.

Rimmer EK, Seftel MD, Israels SJ, Houston DS.

Am J Hematol. 2012 Jan;87(1):122-3. doi: 10.1002/ajh.22190. Epub 2011 Oct 31. No abstract available.

29.

Refinement of the hereditary xerocytosis locus on chromosome 16q in a large Canadian kindred.

Houston BL, Zelinski T, Israels SJ, Coghlan G, Chodirker BN, Gallagher PG, Houston DS, Zarychanski R.

Blood Cells Mol Dis. 2011 Dec 15;47(4):226-31. doi: 10.1016/j.bcmd.2011.08.001. Epub 2011 Sep 25.

PMID:
21944700
30.

Platelet disorders in children: A diagnostic approach.

Israels SJ, Kahr WH, Blanchette VS, Luban NL, Rivard GE, Rand ML.

Pediatr Blood Cancer. 2011 Jun;56(6):975-83. doi: 10.1002/pbc.22988. Epub 2011 Feb 3. Review.

PMID:
21294245
31.

Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry.

Hayward CP, Moffat KA, Raby A, Israels S, Plumhoff E, Flynn G, Zehnder JL.

Am J Clin Pathol. 2010 Dec;134(6):955-63. doi: 10.1309/AJCP9V3RRVNZMKDS.

PMID:
21088160
32.

Inherited disorders of platelet function and challenges to diagnosis of mucocutaneous bleeding.

Israels SJ, El-Ekiaby M, Quiroga T, Mezzano D.

Haemophilia. 2010 Jul;16 Suppl 5:152-9. doi: 10.1111/j.1365-2516.2010.02314.x. Review.

PMID:
20590875
33.

Mechanisms of oral bacteria-induced platelet activation.

McNicol A, Israels SJ.

Can J Physiol Pharmacol. 2010 May;88(5):510-24. doi: 10.1139/y10-029. Review.

PMID:
20555421
34.

Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets.

Israels SJ, McMillan-Ward EM.

Thromb Res. 2010 Feb;125(2):152-8. doi: 10.1016/j.thromres.2009.07.005. Epub 2009 Jul 29.

PMID:
19640571
35.

Diagnostic evaluation of platelet function disorders in neonates and children: an update.

Israels SJ.

Semin Thromb Hemost. 2009 Mar;35(2):181-8. doi: 10.1055/s-0029-1220326. Epub 2009 Apr 30. Review.

PMID:
19408191
36.

Results of an external proficiency testing exercise on platelet dense-granule deficiency testing by whole mount electron microscopy.

Hayward CP, Moffat KA, Spitzer E, Timleck M, Plumhoff E, Israels SJ, White J; NASCOLA Working Group on Platelet Dense Granule Deficiency.

Am J Clin Pathol. 2009 May;131(5):671-5. doi: 10.1309/AJCPYMFXZNSNRZ55.

PMID:
19369626
37.

Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program.

Halton J, Gaboury I, Grant R, Alos N, Cummings EA, Matzinger M, Shenouda N, Lentle B, Abish S, Atkinson S, Cairney E, Dix D, Israels S, Stephure D, Wilson B, Hay J, Moher D, Rauch F, Siminoski K, Ward LM; Canadian STOPP Consortium.

J Bone Miner Res. 2009 Jul;24(7):1326-34. doi: 10.1359/jbmr.090202.

38.

Beyond hemostasis: the role of platelets in inflammation, malignancy and infection.

McNicol A, Israels SJ.

Cardiovasc Hematol Disord Drug Targets. 2008 Jun;8(2):99-117. Review.

PMID:
18537597
39.

A role for von Willebrand factor in Streptococcus sanguis-induced platelet activation.

McNicol A, Eyer E, Jackson EC, Israels SJ.

Thromb Haemost. 2007 Dec;98(6):1382-4. No abstract available.

PMID:
18064343
40.

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

Azad MB, Chen Y, Henson ES, Cizeau J, McMillan-Ward E, Israels SJ, Gibson SB.

Autophagy. 2008 Feb;4(2):195-204. Epub 2007 Nov 8.

41.

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.

Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB.

J Cell Sci. 2007 Dec 1;120(Pt 23):4155-66.

42.

Platelet tetraspanin complexes and their association with lipid rafts.

Israels SJ, McMillan-Ward EM.

Thromb Haemost. 2007 Nov;98(5):1081-7.

PMID:
18000614
43.

Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells.

Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB.

Cell Death Differ. 2008 Jan;15(1):171-82. Epub 2007 Oct 5.

44.

Bleeding disorders: characterization, dental considerations and management.

Israels S, Schwetz N, Boyar R, McNicol A.

J Can Dent Assoc. 2006 Nov;72(9):827.

45.

Antiplatelet therapy in children.

Israels SJ, Michelson AD.

Thromb Res. 2006;118(1):75-83. Epub 2005 Feb 1. Review.

PMID:
16709476
46.

Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study.

Feldman BM, Pai M, Rivard GE, Israels S, Poon MC, Demers C, Robinson S, Luke KH, Wu JK, Gill K, Lillicrap D, Babyn P, McLimont M, Blanchette VS; Association of Hemophilia Clinic Directors of Canada Prophylaxis Study Group.

J Thromb Haemost. 2006 Jun;4(6):1228-36.

47.

CD63 modulates spreading and tyrosine phosphorylation of platelets on immobilized fibrinogen.

Israels SJ, McMillan-Ward EM.

Thromb Haemost. 2005 Feb;93(2):311-8.

PMID:
15711748
48.

A survey of factor prophylaxis in the Canadian haemophilia A population.

Blanchette P, Rivard G, Israels S, Robinson S, Ali K, Walker I, Stain AM, Blanchette V; Association of Hemophilia Clinic Directors of Canada and Canadian Association of Nurses in Hemophilia Care.

Haemophilia. 2004 Nov;10(6):679-83.

PMID:
15569161
49.

Home management of haemophilia.

Teitel JM, Barnard D, Israels S, Lillicrap D, Poon MC, Sek J.

Haemophilia. 2004 Mar;10(2):118-33. Review.

PMID:
14962201
50.

Platelets and anti-platelet therapy.

McNicol A, Israels SJ.

J Pharmacol Sci. 2003 Dec;93(4):381-96. Review.

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