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Items: 1 to 50 of 190

1.

Characterizing the heterogeneity in 5-aminolevulinic acid-induced fluorescence in glioblastoma.

Almiron Bonnin DA, Havrda MC, Lee MC, Evans L, Ran C, Qian DC, Harrington LX, Valdes PA, Cheng C, Amos CI, Harris BT, Paulsen KD, Roberts DW, Israel MA.

J Neurosurg. 2019 May 24:1-9. doi: 10.3171/2019.2.JNS183128. [Epub ahead of print]

PMID:
31125970
2.

Glioma Cell Secretion: A Driver of Tumor Progression and a Potential Therapeutic Target.

Almiron Bonnin DA, Havrda MC, Israel MA.

Cancer Res. 2018 Nov 1;78(21):6031-6039. doi: 10.1158/0008-5472.CAN-18-0345. Epub 2018 Oct 17. Review.

PMID:
30333116
3.

Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia.

Almiron Bonnin DA, Havrda MC, Lee MC, Liu H, Zhang Z, Nguyen LN, Harrington LX, Hassanpour S, Cheng C, Israel MA.

Oncogene. 2018 Feb 22;37(8):1107-1118. doi: 10.1038/onc.2017.404. Epub 2017 Nov 20.

4.

A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma.

Rahme GJ, Luikart BW, Cheng C, Israel MA.

Neuro Oncol. 2018 Feb 19;20(3):332-342. doi: 10.1093/neuonc/nox129.

5.

ID2 promotes survival of glioblastoma cells during metabolic stress by regulating mitochondrial function.

Zhang Z, Rahme GJ, Chatterjee PD, Havrda MC, Israel MA.

Cell Death Dis. 2017 Feb 16;8(2):e2615. doi: 10.1038/cddis.2017.14.

6.

Insulin-Mediated Signaling Facilitates Resistance to PDGFR Inhibition in Proneural hPDGFB-Driven Gliomas.

Almiron Bonnin DA, Ran C, Havrda MC, Liu H, Hitoshi Y, Zhang Z, Cheng C, Ung M, Israel MA.

Mol Cancer Ther. 2017 Apr;16(4):705-716. doi: 10.1158/1535-7163.MCT-16-0616. Epub 2017 Jan 30.

7.

Pediatric Brain Tumors: Current Knowledge and Therapeutic Opportunities.

Glod J, Rahme GJ, Kaur H, H Raabe E, Hwang EI, Israel MA.

J Pediatr Hematol Oncol. 2016 May;38(4):249-60. doi: 10.1097/MPH.0000000000000551. Review.

8.

PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells.

Rahme GJ, Zhang Z, Young AL, Cheng C, Bivona EJ, Fiering SN, Hitoshi Y, Israel MA.

Cancer Res. 2016 May 15;76(10):2964-76. doi: 10.1158/0008-5472.CAN-15-2157. Epub 2016 Mar 7.

9.

Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells.

Sullivan JM, Havrda MC, Kettenbach AN, Paolella BR, Zhang Z, Gerber SA, Israel MA.

Stem Cells. 2016 May;34(5):1321-31. doi: 10.1002/stem.2291. Epub 2016 Feb 1.

10.

Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells.

Young JE, Boulanger-Weill J, Williams DA, Woodruff G, Buen F, Revilla AC, Herrera C, Israel MA, Yuan SH, Edland SD, Goldstein LS.

Cell Stem Cell. 2015 Apr 2;16(4):373-85. doi: 10.1016/j.stem.2015.02.004. Epub 2015 Mar 12.

11.

Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers.

Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH.

JAMA Neurol. 2014 Dec;71(12):1481-9. doi: 10.1001/jamaneurol.2014.2482.

12.

Id2 mediates oligodendrocyte precursor cell maturation arrest and is tumorigenic in a PDGF-rich microenvironment.

Havrda MC, Paolella BR, Ran C, Jering KS, Wray CM, Sullivan JM, Nailor A, Hitoshi Y, Israel MA.

Cancer Res. 2014 Mar 15;74(6):1822-32. doi: 10.1158/0008-5472.CAN-13-1839. Epub 2014 Jan 14.

13.

Id4 suppresses MMP2-mediated invasion of glioblastoma-derived cells by direct inactivation of Twist1 function.

Rahme GJ, Israel MA.

Oncogene. 2015 Jan 2;34(1):53-62. doi: 10.1038/onc.2013.531. Epub 2014 Jan 13.

PMID:
24413082
14.

Serine/threonine kinase 17A is a novel candidate for therapeutic targeting in glioblastoma.

Mao P, Hever-Jardine MP, Rahme GJ, Yang E, Tam J, Kodali A, Biswal B, Fadul CE, Gaur A, Israel MA, Spinella MJ.

PLoS One. 2013 Nov 28;8(11):e81803. doi: 10.1371/journal.pone.0081803. eCollection 2013.

15.

Elevated Id2 expression results in precocious neural stem cell depletion and abnormal brain development.

Park HJ, Hong M, Bronson RT, Israel MA, Frankel WN, Yun K.

Stem Cells. 2013 May;31(5):1010-21. doi: 10.1002/stem.1351.

16.

Proliferation-independent control of tumor glycolysis by PDGFR-mediated AKT activation.

Ran C, Liu H, Hitoshi Y, Israel MA.

Cancer Res. 2013 Mar 15;73(6):1831-43. doi: 10.1158/0008-5472.CAN-12-2460. Epub 2013 Jan 15.

17.

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.

Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS.

Nature. 2012 Jan 25;482(7384):216-20. doi: 10.1038/nature10821.

18.

Genetics of glioblastoma: a window into its imaging and histopathologic variability.

Belden CJ, Valdes PA, Ran C, Pastel DA, Harris BT, Fadul CE, Israel MA, Paulsen K, Roberts DW.

Radiographics. 2011 Oct;31(6):1717-40. doi: 10.1148/rg.316115512. Review.

19.

Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges.

Israel MA, Goldstein LS.

Genome Med. 2011 Jul 27;3(7):49. doi: 10.1186/gm265.

20.

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo.

Gaur AB, Holbeck SL, Colburn NH, Israel MA.

Neuro Oncol. 2011 Jun;13(6):580-90. doi: 10.1093/neuonc/nor033.

21.

p53 directly represses Id2 to inhibit the proliferation of neural progenitor cells.

Paolella BR, Havrda MC, Mantani A, Wray CM, Zhang Z, Israel MA.

Stem Cells. 2011 Jul;29(7):1090-101. doi: 10.1002/stem.660.

22.

Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.

Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, Carson CT.

PLoS One. 2011 Mar 2;6(3):e17540. doi: 10.1371/journal.pone.0017540.

23.

Somatic coding mutations in human induced pluripotent stem cells.

Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K.

Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805.

24.

Investigating synapse formation and function using human pluripotent stem cell-derived neurons.

Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3005-10. doi: 10.1073/pnas.1007753108. Epub 2011 Jan 28.

25.

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation.

Lian I, Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A, Israel MA, Goldstein LS, Abujarour R, Ding S, Guan KL.

Genes Dev. 2010 Jun 1;24(11):1106-18. doi: 10.1101/gad.1903310.

26.

Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice.

Murad JM, Place CS, Ran C, Hekmatyar SK, Watson NP, Kauppinen RA, Israel MA.

J Biol Chem. 2010 Jul 30;285(31):24164-73. doi: 10.1074/jbc.M110.128744. Epub 2010 May 11.

27.

Inhibitor of DNA binding-4 promotes angiogenesis and growth of glioblastoma multiforme by elevating matrix GLA levels.

Kuzontkoski PM, Mulligan-Kehoe MJ, Harris BT, Israel MA.

Oncogene. 2010 Jul 1;29(26):3793-802. doi: 10.1038/onc.2010.147. Epub 2010 May 10.

PMID:
20453881
28.

ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver.

Hou TY, Ward SM, Murad JM, Watson NP, Israel MA, Duffield GE.

J Biol Chem. 2009 Nov 13;284(46):31735-45. doi: 10.1074/jbc.M109.013961. Epub 2009 Sep 9.

29.

A role for Id2 in regulating photic entrainment of the mammalian circadian system.

Duffield GE, Watson NP, Mantani A, Peirson SN, Robles-Murguia M, Loros JJ, Israel MA, Dunlap JC.

Curr Biol. 2009 Feb 24;19(4):297-304. doi: 10.1016/j.cub.2008.12.052. Epub 2009 Feb 12.

30.

Id2 is required for specification of dopaminergic neurons during adult olfactory neurogenesis.

Havrda MC, Harris BT, Mantani A, Ward NM, Paolella BR, Cuzon VC, Yeh HH, Israel MA.

J Neurosci. 2008 Dec 24;28(52):14074-86. doi: 10.1523/JNEUROSCI.3188-08.2008.

31.

Cancer stem cells are enriched in the side population cells in a mouse model of glioma.

Harris MA, Yang H, Low BE, Mukherjee J, Guha A, Bronson RT, Shultz LD, Israel MA, Yun K.

Cancer Res. 2008 Dec 15;68(24):10051-9. doi: 10.1158/0008-5472.CAN-08-0786. Erratum in: Cancer Res. 2009 Jul 15;69(14):6005. Mukherje, Joydeep [corrected to Mukherjee, Joydeep].

32.

Spinal glioma: platelet-derived growth factor B-mediated oncogenesis in the spinal cord.

Hitoshi Y, Harris BT, Liu H, Popko B, Israel MA.

Cancer Res. 2008 Oct 15;68(20):8507-15. doi: 10.1158/0008-5472.CAN-08-1063. Erratum in: Cancer Res. 2008 Nov 15;68(22):9566.

33.

Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment.

Liang Y, Diehn M, Bollen AW, Israel MA, Gupta N.

J Neurooncol. 2008 Jan;86(2):133-41. Epub 2007 Jul 25.

PMID:
17653508
34.

Characterization of microRNA expression levels and their biological correlates in human cancer cell lines.

Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, Ambros VR, Israel MA.

Cancer Res. 2007 Mar 15;67(6):2456-68.

35.
36.

Diffuse encephaloventriculitis and substantial leukoencephalopathy after intraventricular administration of recombinant adenovirus.

Tada T, Nguyen JB, Hitoshi Y, Watson NP, Dunn JF, Ohara S, Nagano S, Kosai K, Israel MA.

Neurol Res. 2005 Jun;27(4):378-86.

PMID:
15949235
37.

Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme.

Liang Y, Diehn M, Watson N, Bollen AW, Aldape KD, Nicholas MK, Lamborn KR, Berger MS, Botstein D, Brown PO, Israel MA.

Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5814-9. Epub 2005 Apr 12.

38.

Id4 regulates neural progenitor proliferation and differentiation in vivo.

Yun K, Mantani A, Garel S, Rubenstein J, Israel MA.

Development. 2004 Nov;131(21):5441-8. Epub 2004 Oct 6.

39.

Id2 is dispensable for Myc-induced epidermal neoplasia.

Murphy DJ, Swigart LB, Israel MA, Evan GI.

Mol Cell Biol. 2004 Mar;24(5):2083-90.

40.

Genetic determinants of malignancy in a mouse model for oligodendroglioma.

Weiss WA, Burns MJ, Hackett C, Aldape K, Hill JR, Kuriyama H, Kuriyama N, Milshteyn N, Roberts T, Wendland MF, DePinho R, Israel MA.

Cancer Res. 2003 Apr 1;63(7):1589-95.

41.

Evidence for lack of enhanced hedgehog target gene expression in common extracutaneous tumors.

Hu Z, Bonifas JM, Aragon G, Kopelovich L, Liang Y, Ohta S, Israel MA, Bickers DR, Aszterbaum M, Epstein EH Jr.

Cancer Res. 2003 Mar 1;63(5):923-8.

42.

Testing of new agents in childhood cancer preclinical models: meeting summary.

Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA.

Clin Cancer Res. 2002 Dec;8(12):3646-57.

43.

Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition?

Brasch RC, Gossmann A, Helbich TH, Kuriyama N, Roberts TP, Shames DM, van Bruggen N, Wendland MF, Israel MA.

Acad Radiol. 2002 Aug;9 Suppl 2:S326-7. No abstract available.

PMID:
12188263
45.

Prognostic significance of an apoptotic index and apoptosis/proliferation ratio for patients with high-grade astrocytomas.

Kuriyama H, Lamborn KR, O'Fallon JR, Iturria N, Sebo T, Schaefer PL, Scheithauer BW, Buckner JC, Kuriyama N, Jenkins RB, Israel MA.

Neuro Oncol. 2002 Jul;4(3):179-86. doi: 10.1093/neuonc/4.3.179.

46.

A head holder for magnetic resonance imaging that allows the stereotaxic alignment of spontaneously occurring intracranial mouse tumors.

Tada T, Wendland M, Watson N, Kuriyama N, Kuriyama H, Roberts T, Burns M, Weiss W, Israel MA.

J Neurosci Methods. 2002 Apr 30;116(1):1-7.

PMID:
12007978
47.

Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme.

Gossmann A, Helbich TH, Kuriyama N, Ostrowitzki S, Roberts TP, Shames DM, van Bruggen N, Wendland MF, Israel MA, Brasch RC.

J Magn Reson Imaging. 2002 Mar;15(3):233-40.

PMID:
11891967
48.

EGFR overexpression and radiation response in glioblastoma multiforme.

Barker FG 2nd, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, Wara WM, Berger MS, Chen P, Israel MA, Aldape KD.

Int J Radiat Oncol Biol Phys. 2001 Oct 1;51(2):410-8.

PMID:
11567815
49.
50.

Overexpression of E2F1 in glioma-derived cell lines induces a p53-independent apoptosis that is further enhanced by ionizing radiation.

Shu HK, Julin CM, Furman F, Yount GL, Haas-Kogan D, Israel MA.

Neuro Oncol. 2000 Jan;2(1):16-21. doi: 10.1093/neuonc/2.1.16.

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