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Items: 18

1.

Piperidine derivatives as nonprostanoid IP receptor agonists 2.

Hayashi R, Ito H, Ishigaki T, Morita Y, Miyamoto M, Isogaya M.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2886-2889. doi: 10.1016/j.bmcl.2016.04.043. Epub 2016 Apr 19.

PMID:
27133594
2.

Piperidine derivatives as nonprostanoid IP receptor agonists.

Hayashi R, Sakagami H, Koiwa M, Ito H, Miyamoto M, Isogaya M.

Bioorg Med Chem Lett. 2016 May 1;26(9):2360-4. doi: 10.1016/j.bmcl.2016.03.009. Epub 2016 Mar 4.

PMID:
26996371
3.

Indolylpiperidine derivatives as potent and selective α1B adrenoceptor antagonists.

Hayashi R, Ohmori E, Moriwaki M, Kumagai H, Isogaya M.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3921-3. doi: 10.1016/j.bmcl.2015.07.046. Epub 2015 Jul 22.

PMID:
26238322
4.

Synthesis of novel IP agonists via N-aminoethyl cyclic amines prepared by decarboxylative ring-opening reactions.

Morita Y, Ishigaki T, Kawamura K, Hayashi R, Isogaya M, Kitsukawa M, Miyamoto M, Uchida M, Iseki K.

Molecules. 2012 Jan 31;17(2):1233-46. doi: 10.3390/molecules17021233.

5.

Efficient synthesis of a novel m-phenylene derivative as a selective EP4 agonist inducing follicular growth and maturation in the ovary.

Hayashi R, Hosono Y, Nakatsuji K, Tanaka Y, Mori T, Kanno T, Makita K, Moriwaki M, Ohyama T, Ochi Y, Inada C, Isogaya M.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7505-8. doi: 10.1016/j.bmcl.2011.09.004. Epub 2011 Oct 1.

PMID:
22061638
6.

Design and synthesis of selective alpha1B adrenoceptor antagonists.

Hayashi R, Ohmori E, Isogaya M, Moriwaki M, Kumagai H.

Bioorg Med Chem Lett. 2006 Aug 1;16(15):4045-7. Epub 2006 May 24.

PMID:
16723224
7.
8.

Enhanced cAMP response of naturally occurring mutant of human beta3-adrenergic receptor.

Isogaya M, Nagao T, Kurose H.

Jpn J Pharmacol. 2002 Mar;88(3):314-8.

9.

Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.

Isogaya M, Sugimoto Y, Tanimura R, Tanaka R, Kikkawa H, Nagao T, Kurose H.

Mol Pharmacol. 1999 Nov;56(5):875-85.

PMID:
10531390
10.

Identification of a key amino acid of the beta2-adrenergic receptor for high affinity binding of salmeterol.

Isogaya M, Yamagiwa Y, Fujita S, Sugimoto Y, Nagao T, Kurose H.

Mol Pharmacol. 1998 Oct;54(4):616-22.

PMID:
9765503
11.

Domains of beta1 and beta2 adrenergic receptors to bind subtype selective agonists.

Kurose H, Isogaya M, Kikkawa H, Nagao T.

Life Sci. 1998;62(17-18):1513-7. Review.

PMID:
9585128
12.

The role of the seventh transmembrane region in high affinity binding of a beta 2-selective agonist TA-2005.

Kikkawa H, Isogaya M, Nagao T, Kurose H.

Mol Pharmacol. 1998 Jan;53(1):128-34.

PMID:
9443940
14.

Molecular characterization of pharmacological properties of T-0509 for beta-adrenoceptors.

Sato Y, Kurose H, Isogaya M, Nagao T.

Eur J Pharmacol. 1996 Nov 21;315(3):363-7.

PMID:
8982677
15.

Positive inotropic and chronotropic effects of beraprost sodium, a stable analogue of prostacyclin, in isolated guinea pig myocardium.

Ueno Y, Okazaki S, Isogaya M, Nishio S, Tanaka H, Kato Y, Shigenobu K.

Gen Pharmacol. 1996 Jan;27(1):101-3.

PMID:
8742503
16.

Inhibition of restenosis by beraprost sodium (a prostaglandin I2 analogue) in the atherosclerotic rabbit artery after angioplasty.

Isogaya M, Yamada N, Koike H, Ueno Y, Kumagai H, Ochi Y, Okazaki S, Nishio S.

J Cardiovasc Pharmacol. 1995 Jun;25(6):947-52.

PMID:
7564340
17.

Effect of beraprost sodium on peripheral circulatory disturbances induced by various stimuli.

Nishio S, Yamada N, Endoh T, Isogaya M, Fukatsu Y, Nishimura S, Kanai N, Umetsu T.

Arzneimittelforschung. 1989 Oct;39(10):1229-34.

PMID:
2514691
18.

Atropine- and hexamethonium-resistant motor response to greater splanchnic nerve stimulation in the dog stomach.

Nakazato Y, Sekine H, Isogaya M, Ito S, Ohga A.

J Auton Nerv Syst. 1987 Jul;20(1):35-42.

PMID:
2443547

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