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Items: 27

1.

Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control.

Hawkes W, Huang D, Reynolds P, Hammond L, Ward M, Gadegaard N, Marshall JF, Iskratsch T, Palma M.

Faraday Discuss. 2019 Jul 17. doi: 10.1039/c9fd00023b. [Epub ahead of print]

PMID:
31314021
2.

Costameres, dense plaques and podosomes: the cell matrix adhesions in cardiovascular mechanosensing.

Sit B, Gutmann D, Iskratsch T.

J Muscle Res Cell Motil. 2019 Jun;40(2):197-209. doi: 10.1007/s10974-019-09529-7. Epub 2019 Jun 18.

PMID:
31214894
3.

Lamin-A Mechano-Protects the Heart.

Xanthis I, Iskratsch T.

Dev Cell. 2019 Jun 17;49(6):821-822. doi: 10.1016/j.devcel.2019.05.041.

PMID:
31211988
4.

Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.

Pedrosa AR, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T, Hodivala-Dilke KM.

Cancer Res. 2019 Sep 1;79(17):4371-4386. doi: 10.1158/0008-5472.CAN-18-3934. Epub 2019 Jun 12.

PMID:
31189647
5.

Mix and (mis-)match - The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart.

Ward M, Iskratsch T.

Biochim Biophys Acta Mol Cell Res. 2019 Feb 8. pii: S0167-4889(18)30325-2. doi: 10.1016/j.bbamcr.2019.01.017. [Epub ahead of print] Review.

6.

Calponin-3 is critical for coordinated contractility of actin stress fibers.

Ciuba K, Hawkes W, Tojkander S, Kogan K, Engel U, Iskratsch T, Lappalainen P.

Sci Rep. 2018 Dec 5;8(1):17670. doi: 10.1038/s41598-018-35948-6.

7.

Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions.

Pandey P, Hawkes W, Hu J, Megone WV, Gautrot J, Anilkumar N, Zhang M, Hirvonen L, Cox S, Ehler E, Hone J, Sheetz M, Iskratsch T.

Dev Cell. 2018 Jun 4;45(5):661. doi: 10.1016/j.devcel.2018.05.016. No abstract available.

8.

Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions.

Pandey P, Hawkes W, Hu J, Megone WV, Gautrot J, Anilkumar N, Zhang M, Hirvonen L, Cox S, Ehler E, Hone J, Sheetz M, Iskratsch T.

Dev Cell. 2018 Feb 5;44(3):326-336.e3. doi: 10.1016/j.devcel.2017.12.024. Epub 2018 Jan 26. Erratum in: Dev Cell. 2018 Jun 4;45(5):661.

9.

α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions.

Meacci G, Wolfenson H, Liu S, Stachowiak MR, Iskratsch T, Mathur A, Ghassemi S, Gauthier N, Tabdanov E, Lohner J, Gondarenko A, Chander AC, Roca-Cusachs P, O'Shaughnessy B, Hone J, Sheetz MP.

Mol Biol Cell. 2016 Nov 7;27(22):3471-3479. Epub 2016 Apr 27.

10.

Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability.

Santos LC, Blair DA, Kumari S, Cammer M, Iskratsch T, Herbin O, Alexandropoulos K, Dustin ML, Sheetz MP.

Immunol Cell Biol. 2016 Nov;94(10):981-993. doi: 10.1038/icb.2016.61. Epub 2016 Jun 30.

11.

Polymer fiber-based models of connective tissue repair and healing.

Lee NM, Erisken C, Iskratsch T, Sheetz M, Levine WN, Lu HH.

Biomaterials. 2017 Jan;112:303-312. doi: 10.1016/j.biomaterials.2016.10.013. Epub 2016 Oct 12.

12.

Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices.

Wolfenson H, Meacci G, Liu S, Stachowiak MR, Iskratsch T, Ghassemi S, Roca-Cusachs P, O'Shaughnessy B, Hone J, Sheetz MP.

Nat Cell Biol. 2016 Jan;18(1):33-42. doi: 10.1038/ncb3277. Epub 2015 Nov 30.

13.

Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells.

Tabdanov E, Gondarenko S, Kumari S, Liapis A, Dustin ML, Sheetz MP, Kam LC, Iskratsch T.

Integr Biol (Camb). 2015 Oct;7(10):1272-84. doi: 10.1039/c5ib00032g. Epub 2015 Jul 9.

14.

Early events in cell spreading as a model for quantitative analysis of biomechanical events.

Wolfenson H, Iskratsch T, Sheetz MP.

Biophys J. 2014 Dec 2;107(11):2508-14. doi: 10.1016/j.bpj.2014.10.041. Epub 2014 Dec 2. Review.

15.

Appreciating force and shape—the rise of mechanotransduction in cell biology.

Iskratsch T, Wolfenson H, Sheetz MP.

Nat Rev Mol Cell Biol. 2014 Dec;15(12):825-33. doi: 10.1038/nrm3903. Epub 2014 Oct 30. Review.

PMID:
25355507
16.

The formin FHOD1 in cardiomyocytes.

Dwyer J, Pluess M, Iskratsch T, Dos Remedios CG, Ehler E.

Anat Rec (Hoboken). 2014 Sep;297(9):1560-70. doi: 10.1002/ar.22984.

17.

N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.

Zhang X, Moore SW, Iskratsch T, Sheetz MP.

J Cell Sci. 2014 Apr 1;127(Pt 7):1394-405. doi: 10.1242/jcs.134692. Epub 2014 Jan 30.

18.

FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration.

Iskratsch T, Yu CH, Mathur A, Liu S, Stévenin V, Dwyer J, Hone J, Ehler E, Sheetz M.

Dev Cell. 2013 Dec 9;27(5):545-59. doi: 10.1016/j.devcel.2013.11.003.

19.

Endoplasmic spreading requires coalescence of vimentin intermediate filaments at force-bearing adhesions.

Lynch CD, Lazar AM, Iskratsch T, Zhang X, Sheetz MP.

Mol Biol Cell. 2013 Jan;24(1):21-30. doi: 10.1091/mbc.E12-05-0377. Epub 2012 Oct 31.

20.

Two distinct phosphorylation events govern the function of muscle FHOD3.

Iskratsch T, Reijntjes S, Dwyer J, Toselli P, Dégano IR, Dominguez I, Ehler E.

Cell Mol Life Sci. 2013 Mar;70(5):893-908. doi: 10.1007/s00018-012-1154-7. Epub 2012 Oct 4.

21.

Finding the weakest link: exploring integrin-mediated mechanical molecular pathways.

Roca-Cusachs P, Iskratsch T, Sheetz MP.

J Cell Sci. 2012 Jul 1;125(Pt 13):3025-38. doi: 10.1242/jcs.095794. Epub 2012 Jul 13. Review.

22.

Actin in striated muscle: recent insights into assembly and maintenance.

Dwyer J, Iskratsch T, Ehler E.

Biophys Rev. 2012 Mar;4(1):17-25. doi: 10.1007/s12551-011-0062-7. Epub 2011 Dec 20. Review.

23.

Formin-g muscle cytoarchitecture.

Iskratsch T, Ehler E.

Bioarchitecture. 2011 Mar;1(2):66-68.

24.

Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance.

Iskratsch T, Lange S, Dwyer J, Kho AL, dos Remedios C, Ehler E.

J Cell Biol. 2010 Dec 13;191(6):1159-72. doi: 10.1083/jcb.201005060.

25.

Aberrant development of neuromuscular junctions in glycosylation-defective Large(myd) mice.

Herbst R, Iskratsch T, Unger E, Bittner RE.

Neuromuscul Disord. 2009 May;19(5):366-78. doi: 10.1016/j.nmd.2009.02.011. Epub 2009 Apr 5.

26.

Specificity analysis of lectins and antibodies using remodeled glycoproteins.

Iskratsch T, Braun A, Paschinger K, Wilson IB.

Anal Biochem. 2009 Mar 15;386(2):133-46. doi: 10.1016/j.ab.2008.12.005. Epub 2008 Dec 14.

PMID:
19123999
27.

Mammalian cells contain a second nucleocytoplasmic hexosaminidase.

Gutternigg M, Rendić D, Voglauer R, Iskratsch T, Wilson IB.

Biochem J. 2009 Apr 1;419(1):83-90. doi: 10.1042/BJ20081630.

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