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Items: 19


CRISPR/Cas9-Mediated Knockout of DNAJC14 Verifies This Chaperone as a Pivotal Host Factor for RNA Replication of Pestiviruses.

Isken O, Postel A, Bruhn B, Lattwein E, Becher P, Tautz N.

J Virol. 2019 Feb 19;93(5). pii: e01714-18. doi: 10.1128/JVI.01714-18. Print 2019 Mar 1.


Correction: A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication.

Isken O, Langerwisch U, Jirasko V, Rehders D, Redecke L, Ramanathan H, Lindenbach BD, Bartenschlager R, Tautz N.

PLoS Pathog. 2016 Jan 8;12(1):e1005394. doi: 10.1371/journal.ppat.1005394. eCollection 2016 Jan.


Polyprotein-Driven Formation of Two Interdependent Sets of Complexes Supporting Hepatitis C Virus Genome Replication.

Gomes RG, Isken O, Tautz N, McLauchlan J, McCormick CJ.

J Virol. 2015 Dec 30;90(6):2868-83. doi: 10.1128/JVI.01931-15.


A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication.

Isken O, Langerwisch U, Jirasko V, Rehders D, Redecke L, Ramanathan H, Lindenbach BD, Bartenschlager R, Tautz N.

PLoS Pathog. 2015 Mar 16;11(3):e1004736. doi: 10.1371/journal.ppat.1004736. eCollection 2015 Mar. Erratum in: PLoS Pathog. 2016 Jan;12(1):e1005394.


Functional characterization of bovine viral diarrhea virus nonstructural protein 5A by reverse genetic analysis and live cell imaging.

Isken O, Langerwisch U, Schönherr R, Lamp B, Schröder K, Duden R, Rümenapf TH, Tautz N.

J Virol. 2014 Jan;88(1):82-98. doi: 10.1128/JVI.01957-13. Epub 2013 Oct 16.


The pioneer round of translation: features and functions.

Maquat LE, Tarn WY, Isken O.

Cell. 2010 Aug 6;142(3):368-74. doi: 10.1016/j.cell.2010.07.022.


Telomeric RNAs as a novel player in telomeric integrity.

Isken O, Maquat LE.

F1000 Biol Rep. 2009;1:90. doi: 10.3410/B1-90. Epub 2009 Nov 26.


The multiple lives of NMD factors: balancing roles in gene and genome regulation.

Isken O, Maquat LE.

Nat Rev Genet. 2008 Sep;9(9):699-712. doi: 10.1038/nrg2402. Review.


Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay.

Isken O, Kim YK, Hosoda N, Mayeur GL, Hershey JW, Maquat LE.

Cell. 2008 Apr 18;133(2):314-27. doi: 10.1016/j.cell.2008.02.030.


NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA.

Woeller CF, Gaspari M, Isken O, Maquat LE.

EMBO Rep. 2008 May;9(5):446-51. doi: 10.1038/embor.2008.36. Epub 2008 Mar 28.


Nuclear factors are involved in hepatitis C virus RNA replication.

Isken O, Baroth M, Grassmann CW, Weinlich S, Ostareck DH, Ostareck-Lederer A, Behrens SE.

RNA. 2007 Oct;13(10):1675-92. Epub 2007 Aug 7.


Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function.

Isken O, Maquat LE.

Genes Dev. 2007 Aug 1;21(15):1833-56. Review.


Members of the NF90/NFAR protein group are involved in the life cycle of a positive-strand RNA virus.

Isken O, Grassmann CW, Sarisky RT, Kann M, Zhang S, Grosse F, Kao PN, Behrens SE.

EMBO J. 2003 Nov 3;22(21):5655-65.


Replication studies using genotype 1a subgenomic hepatitis C virus replicons.

Gu B, Gates AT, Isken O, Behrens SE, Sarisky RT.

J Virol. 2003 May;77(9):5352-9.


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