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Items: 1 to 50 of 152

1.

Coordination of a single calcium ion in the EF-hand maintains the off state of the stromal interaction molecule luminal domain.

Enomoto M, Nishikawa T, Back SI, Ishiyama N, Zheng L, Stathopulos PB, Ikura M.

J Mol Biol. 2019 Oct 15. pii: S0022-2836(19)30594-7. doi: 10.1016/j.jmb.2019.10.003. [Epub ahead of print]

PMID:
31626806
2.

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions.

Ishiyama N, Sarpal R, Wood MN, Barrick SK, Nishikawa T, Hayashi H, Kobb AB, Flozak AS, Yemelyanov A, Fernandez-Gonzalez R, Yonemura S, Leckband DE, Gottardi CJ, Tepass U, Ikura M.

Nat Commun. 2018 Nov 30;9(1):5121. doi: 10.1038/s41467-018-07481-7.

3.

Metapopulation stability in branching river networks.

Terui A, Ishiyama N, Urabe H, Ono S, Finlay JC, Nakamura F.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5963-E5969. doi: 10.1073/pnas.1800060115. Epub 2018 Jun 12. Erratum in: Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1067-1068.

4.

Predicting the ecological impacts of large-dam removals on a river network based on habitat-network structure and flow regimes.

Ishiyama N, Ryo M, Kataoka T, Nagayama S, Sueyoshi M, Terui A, Mori T, Akasaka T, Nakamura F.

Conserv Biol. 2018 Dec;32(6):1403-1413. doi: 10.1111/cobi.13137. Epub 2018 Aug 24.

PMID:
29785835
5.

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

Sandí MJ, Marshall CB, Balan M, Coyaud É, Zhou M, Monson DM, Ishiyama N, Chandrakumar AA, La Rose J, Couzens AL, Gingras AC, Raught B, Xu W, Ikura M, Morrison DK, Rottapel R.

Sci Signal. 2017 Oct 31;10(503). pii: eaan3286. doi: 10.1126/scisignal.aan3286.

6.

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.

Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M.

Nat Commun. 2017 Oct 23;8(1):1099. doi: 10.1038/s41467-017-01326-5.

7.

α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion.

Wood MN, Ishiyama N, Singaram I, Chung CM, Flozak AS, Yemelyanov A, Ikura M, Cho W, Gottardi CJ.

J Cell Biol. 2017 Nov 6;216(11):3767-3783. doi: 10.1083/jcb.201612006. Epub 2017 Sep 5.

8.

Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women.

Tokita Y, Maejima Y, Shimomura K, Takenoshita S, Ishiyama N, Akuzawa M, Shimomura Y, Nakajima K.

Intern Med. 2017;56(7):763-771. doi: 10.2169/internalmedicine.56.7115. Epub 2017 Apr 1.

9.

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.

Mège RM, Ishiyama N.

Cold Spring Harb Perspect Biol. 2017 May 1;9(5). pii: a028738. doi: 10.1101/cshperspect.a028738. Review.

10.

Lipoprotein lipase does not increase significantly in the postprandial plasma.

Ishiyama N, Sakamaki K, Shimomura Y, Kotani K, Tsuzaki K, Sakane N, Miyashita K, Fukamachi I, Kobayashi J, Stanhope KL, Havel PJ, Kamachi K, Tanaka A, Tokita Y, Machida T, Murakami M, Nakajima K.

Clin Chim Acta. 2017 Jan;464:204-210. doi: 10.1016/j.cca.2016.11.035. Epub 2016 Nov 29.

PMID:
27908779
11.

Backbone resonance assignments of the F-actin binding domain of mouse αN-catenin.

Nishikawa T, Ishiyama N, Wang F, Ikura M.

Biomol NMR Assign. 2017 Apr;11(1):21-24. doi: 10.1007/s12104-016-9713-8. Epub 2016 Nov 1.

PMID:
27804064
12.

An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function.

Zheng W, Umitsu M, Jagan I, Tran CW, Ishiyama N, BeGora M, Araki K, Ohashi PS, Ikura M, Muthuswamy SK.

Nat Cell Biol. 2016 Nov;18(11):1244-1252. doi: 10.1038/ncb3413. Epub 2016 Oct 3.

PMID:
27694890
13.

To what extent do human-altered landscapes retain population connectivity? Historical changes in gene flow of wetland fish Pungitius pungitius.

Ishiyama N, Sueyoshi M, Nakamura F.

R Soc Open Sci. 2015 Jul 8;2(7):150033. doi: 10.1098/rsos.150033. eCollection 2015 Jul.

14.

Structural Determinants of the Mechanical Stability of α-Catenin.

Li J, Newhall J, Ishiyama N, Gottardi C, Ikura M, Leckband DE, Tajkhorshid E.

J Biol Chem. 2015 Jul 31;290(31):18890-903. doi: 10.1074/jbc.M115.647941. Epub 2015 Jun 12.

15.

Self-awareness of fast eating and its impact on diagnostic components of metabolic syndrome among middle-aged Japanese males and females.

Nohara A, Maejima Y, Shimomura K, Kumamoto K, Takahashi M, Akuzawa M, Negishi M, Ishiyama N, Nagano N, Aso Y, Takenoshita S, Shimomura Y.

Endocr Regul. 2015 Apr;49(2):91-6.

PMID:
25960010
16.

α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.

Escobar DJ, Desai R, Ishiyama N, Folmsbee SS, Novak MN, Flozak AS, Daugherty RL, Mo R, Nanavati D, Sarpal R, Leckband D, Ikura M, Tepass U, Gottardi CJ.

J Cell Sci. 2015 Mar 15;128(6):1150-65. doi: 10.1242/jcs.163824. Epub 2015 Feb 4.

17.

Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors.

Seo MD, Enomoto M, Ishiyama N, Stathopulos PB, Ikura M.

Biochim Biophys Acta. 2015 Sep;1853(9):1980-91. doi: 10.1016/j.bbamcr.2014.11.023. Epub 2014 Nov 25. Review.

18.

Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).

Mazhab-Jafari MT, Marshall CB, Ho J, Ishiyama N, Stambolic V, Ikura M.

J Biol Chem. 2014 May 2;289(18):12195-201. doi: 10.1074/jbc.C113.543736. Epub 2014 Mar 19.

19.

Degalactosylated/desialylated human serum containing GcMAF induces macrophage phagocytic activity and in vivo antitumor activity.

Kuchiike D, Uto Y, Mukai H, Ishiyama N, Abe C, Tanaka D, Kawai T, Kubo K, Mette M, Inui T, Endo Y, Hori H.

Anticancer Res. 2013 Jul;33(7):2881-5.

PMID:
23780974
20.

An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions.

Ishiyama N, Tanaka N, Abe K, Yang YJ, Abbas YM, Umitsu M, Nagar B, Bueler SA, Rubinstein JL, Takeichi M, Ikura M.

J Biol Chem. 2013 May 31;288(22):15913-25. doi: 10.1074/jbc.M113.453928. Epub 2013 Apr 15.

21.

Monomeric α-catenin links cadherin to the actin cytoskeleton.

Desai R, Sarpal R, Ishiyama N, Pellikka M, Ikura M, Tepass U.

Nat Cell Biol. 2013 Mar;15(3):261-73. doi: 10.1038/ncb2685. Epub 2013 Feb 17.

PMID:
23417122
22.

Themes and variations in ER/SR calcium release channels: structure and function.

Stathopulos PB, Seo MD, Enomoto M, Amador FJ, Ishiyama N, Ikura M.

Physiology (Bethesda). 2012 Dec;27(6):331-42. doi: 10.1152/physiol.00013.2012. Review.

23.

p120-catenin binding masks an endocytic signal conserved in classical cadherins.

Nanes BA, Chiasson-MacKenzie C, Lowery AM, Ishiyama N, Faundez V, Ikura M, Vincent PA, Kowalczyk AP.

J Cell Biol. 2012 Oct 15;199(2):365-80. doi: 10.1083/jcb.201205029.

24.

Structural determination of the phosphorylation domain of the ryanodine receptor.

Sharma P, Ishiyama N, Nair U, Li W, Dong A, Miyake T, Wilson A, Ryan T, MacLennan DH, Kislinger T, Ikura M, Dhe-Paganon S, Gramolini AO.

FEBS J. 2012 Oct;279(20):3952-64. doi: 10.1111/j.1742-4658.2012.08755.x. Epub 2012 Sep 11.

25.

An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis.

Mazhab-Jafari MT, Marshall CB, Ishiyama N, Ho J, Di Palma V, Stambolic V, Ikura M.

Structure. 2012 Sep 5;20(9):1528-39. doi: 10.1016/j.str.2012.06.013. Epub 2012 Jul 19.

26.

The three-dimensional structure of the cadherin-catenin complex.

Ishiyama N, Ikura M.

Subcell Biochem. 2012;60:39-62. doi: 10.1007/978-94-007-4186-7_3. Review.

PMID:
22674067
27.

β-Galactosidase treatment is a common first-stage modification of the three major subtypes of Gc protein to GcMAF.

Uto Y, Yamamoto S, Mukai H, Ishiyama N, Takeuchi R, Nakagawa Y, Hirota K, Terada H, Onizuka S, Hori H.

Anticancer Res. 2012 Jun;32(6):2359-64.

PMID:
22641675
28.

Structural and functional conservation of key domains in InsP3 and ryanodine receptors.

Seo MD, Velamakanni S, Ishiyama N, Stathopulos PB, Rossi AM, Khan SA, Dale P, Li C, Ames JB, Ikura M, Taylor CW.

Nature. 2012 Jan 29;483(7387):108-12. doi: 10.1038/nature10751.

29.

[A case of glomerulonephritis associated with ventriculo-atrial shunt].

Kikuchi R, Tabuse M, Miyazaki H, Ishiyama N, Imafuku T, Kameyama K.

No Shinkei Geka. 2012 Jan;40(1):31-6. Japanese.

PMID:
22223520
30.

[A case of multifocal fibrosclerosis presenting with chronic subdural hematoma].

Miyazaki H, Tabuse M, Ishiyama N, Kikuchi R, Ogihara T, Nanki K.

Brain Nerve. 2011 Jul;63(7):795-9. Japanese.

PMID:
21747150
31.

Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair.

Ishiyama N, Moro T, Ohe T, Miura T, Ishihara K, Konno T, Ohyama T, Kimura M, Kyomoto M, Saito T, Nakamura K, Kawaguchi H.

J Bone Joint Surg Am. 2011 Jan 19;93(2):142-9. doi: 10.2106/JBJS.I.01634.

PMID:
21248211
32.

Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

Chan J, Yamazaki H, Ishiyama N, Seo MD, Mal TK, Michikawa T, Mikoshiba K, Ikura M.

J Biol Chem. 2010 Nov 12;285(46):36092-9. doi: 10.1074/jbc.M110.140160. Epub 2010 Sep 15.

33.

Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.

Ishiyama N, Lee SH, Liu S, Li GY, Smith MJ, Reichardt LF, Ikura M.

Cell. 2010 Apr 2;141(1):117-28. doi: 10.1016/j.cell.2010.01.017.

34.

The prevention of peritendinous adhesions by a phospholipid polymer hydrogel formed in situ by spontaneous intermolecular interactions.

Ishiyama N, Moro T, Ishihara K, Ohe T, Miura T, Konno T, Ohyama T, Kimura M, Kyomoto M, Nakamura K, Kawaguchi H.

Biomaterials. 2010 May;31(14):4009-16. doi: 10.1016/j.biomaterials.2010.01.100. Epub 2010 Feb 10.

PMID:
20149434
35.

Efficient synthesis of 3-arylphthalides using palladium-catalyzed arylation of aldehydes with organoboronic acids.

Kuriyama M, Ishiyama N, Shimazawa R, Shirai R, Onomura O.

J Org Chem. 2009 Dec 4;74(23):9210-3. doi: 10.1021/jo901964k.

PMID:
19873994
36.

Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation "hot spot" loop.

Amador FJ, Liu S, Ishiyama N, Plevin MJ, Wilson A, MacLennan DH, Ikura M.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11040-4. doi: 10.1073/pnas.0905186106. Epub 2009 Jun 18.

37.

Flagellin glycosylation in Pseudomonas aeruginosa PAK requires the O-antigen biosynthesis enzyme WbpO.

Miller WL, Matewish MJ, McNally DJ, Ishiyama N, Anderson EM, Brewer D, Brisson JR, Berghuis AM, Lam JS.

J Biol Chem. 2008 Feb 8;283(6):3507-18. Epub 2007 Dec 7.

38.

Single photon emission computed tomography of reversible magnetic resonance imaging abnormalities of deep cerebral venous thrombosis accompanied with malignant glioma.

Hayashi T, Miyazaki H, Toda Y, Ishiyama N.

Surg Neurol. 2007 Feb;67(2):195-9; discussion 199. Epub 2006 Nov 3.

PMID:
17254891
39.

Structural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity.

Ishiyama N, Creuzenet C, Miller WL, Demendi M, Anderson EM, Harauz G, Lam JS, Berghuis AM.

J Biol Chem. 2006 Aug 25;281(34):24489-95. Epub 2006 May 1.

40.

[Present state of outpatient consultation in Gunma University Hospital].

Ishiyama N, Murakami M.

Rinsho Byori. 2006 Mar;54(3):237-42. Japanese.

PMID:
16637571
41.

Relationships between blood rheology and age, body mass index, blood cell count, fibrinogen, and lipids in healthy subjects.

Seki K, Sumino H, Nara M, Ishiyama N, Nishino M, Murakami M.

Clin Hemorheol Microcirc. 2006;34(3):401-10.

PMID:
16614464
42.

Different responses in adult and neonatal hearts to changes in coronary perfusion pressure.

Ishiyama N, Morita S, Nishida T, Yasui H.

Pediatr Cardiol. 2006 Jan-Feb;27(1):13-18. doi: 10.1007/s00246-005-0772-3.

PMID:
16391978
43.

Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets.

Ishiyama N, Ravier MA, Henquin JC.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E540-9. Epub 2005 Oct 25.

44.

[Speech disturbance following myelography with iohexol: a case report].

Hayashi T, Miyazaki H, Toda Y, Ishiyama N, Harada T.

No To Shinkei. 2005 Sep;57(9):796-9. Japanese.

PMID:
16248368
45.

Towards a better understanding of the substrate specificity of the UDP-N-acetylglucosamine C4 epimerase WbpP.

Demendi M, Ishiyama N, Lam JS, Berghuis AM, Creuzenet C.

Biochem J. 2005 Jul 1;389(Pt 1):173-80.

46.

A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni.

Bernatchez S, Szymanski CM, Ishiyama N, Li J, Jarrell HC, Lau PC, Berghuis AM, Young NM, Wakarchuk WW.

J Biol Chem. 2005 Feb 11;280(6):4792-802. Epub 2004 Oct 27.

47.

Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis.

Harauz G, Ishiyama N, Hill CM, Bates IR, Libich DS, Farès C.

Micron. 2004;35(7):503-42. Review.

PMID:
15219899
48.

Hepatocellular carcinoma containing sarcomatous lesions in a normal liver, accompanied by secondary Budd-Chiari syndrome.

Kishino T, Mori H, Nishikawa K, Ishiyama N, Yasui H, Sugiyama M, Atomi Y, Sakamoto M, Saito S, Ishida H, Takahashi S, Watanabe T.

J Clin Gastroenterol. 2004 Mar;38(3):296-7. No abstract available.

PMID:
15128080
50.

[A duplication of middle cerebral artery mimicking a cerebral aneurysm].

Hayashi T, Miyazaki H, Ichimura S, Ishiyama N.

No To Shinkei. 2004 Feb;56(2):174-5. Japanese. No abstract available.

PMID:
15098364

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