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Items: 1 to 50 of 76

1.

[Live-imaging Analyses Using Small Fish Models Reveal New Mechanisms That Regulate Primary Tumorigenesis].

Haraoka Y, Akieda Y, Ishitani T.

Yakugaku Zasshi. 2019;139(5):733-741. doi: 10.1248/yakushi.18-00185-1. Review. Japanese.

2.

Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite.

Abe K, Shimada A, Tayama S, Nishikawa H, Kaneko T, Tsuda S, Karaiwa A, Matsui T, Ishitani T, Takeda H.

Cell Rep. 2019 Apr 16;27(3):928-939.e4. doi: 10.1016/j.celrep.2019.03.068.

3.

Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology.

Watanave M, Hoshino C, Konno A, Fukuzaki Y, Matsuzaki Y, Ishitani T, Hirai H.

Neurobiol Dis. 2019 Jan;121:263-273. doi: 10.1016/j.nbd.2018.10.014. Epub 2018 Oct 19.

PMID:
30343032
4.

Involvement of sonic hedgehog and notch signaling in regenerative neurogenesis in adult zebrafish optic tectum after stab injury.

Ueda Y, Shimizu Y, Shimizu N, Ishitani T, Ohshima T.

J Comp Neurol. 2018 Oct 15;526(15):2360-2372. doi: 10.1002/cne.24489. Epub 2018 Aug 25.

PMID:
30014463
5.

Purification of zebrafish erythrocytes as a means of identifying a novel regulator of haematopoiesis.

Kulkeaw K, Inoue T, Ishitani T, Nakanishi Y, Zon LI, Sugiyama D.

Br J Haematol. 2018 Feb;180(3):420-431. doi: 10.1111/bjh.15048. Epub 2017 Dec 19.

6.

Induction of intrinsic apoptosis in leukaemia stem cells and in vivo zebrafish model by betulonic acid isolated from Walsura pinnata Hassk (Meliaceae).

Leong KH, Mahdzir MA, Din MF, Awang K, Tanaka Y, Kulkeaw K, Ishitani T, Sugiyama D.

Phytomedicine. 2017 Mar 15;26:11-21. doi: 10.1016/j.phymed.2016.12.018. Epub 2017 Jan 9.

PMID:
28257660
7.

Wip1 directly dephosphorylates NLK and increases Wnt activity during germ cell development.

Cho SJ, Cha BS, Kwon OS, Lim J, Shin DM, Han DW, Ishitani T, Jho EH, Fornace AJ, Cha HJ.

Biochim Biophys Acta Mol Basis Dis. 2017 Apr;1863(4):1013-1022. doi: 10.1016/j.bbadis.2017.01.028. Epub 2017 Feb 7.

8.

Context-dependent regulation of the β-catenin transcriptional complex supports diverse functions of Wnt/β-catenin signaling.

Masuda T, Ishitani T.

J Biochem. 2017 Jan;161(1):9-17. doi: 10.1093/jb/mvw072. Epub 2016 Dec 24. Review.

PMID:
28013224
9.

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.

Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y.

J Clin Invest. 2017 Jan 3;127(1):137-152. doi: 10.1172/JCI88486. Epub 2016 Nov 21.

10.

Factors controlling denitrification of mudflat sediments in Ariake Bay, Japan.

Koriyama M, Koga A, Seguchi M, Ishitani T.

Environ Monit Assess. 2016 Feb;188(2):96. doi: 10.1007/s10661-016-5101-1. Epub 2016 Jan 16.

PMID:
26780415
11.

In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma.

Sa JK, Yoon Y, Kim M, Kim Y, Cho HJ, Lee JK, Kim GS, Han S, Kim WJ, Shin YJ, Joo KM, Paddison PJ, Ishitani T, Lee J, Nam DH.

Oncotarget. 2015 Aug 21;6(24):20145-59.

12.

Biochemical characterization of three BLT receptors in zebrafish.

Okuno T, Ishitani T, Yokomizo T.

PLoS One. 2015 Mar 4;10(3):e0117888. doi: 10.1371/journal.pone.0117888. eCollection 2015.

13.

Hipk2 and PP1c cooperate to maintain Dvl protein levels required for Wnt signal transduction.

Shimizu N, Ishitani S, Sato A, Shibuya H, Ishitani T.

Cell Rep. 2014 Sep 11;8(5):1391-404. doi: 10.1016/j.celrep.2014.07.040. Epub 2014 Aug 21.

14.

Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway.

Saita S, Shirane M, Ishitani T, Shimizu N, Nakayama KI.

J Biol Chem. 2014 Sep 12;289(37):25639-54. doi: 10.1074/jbc.M114.558635. Epub 2014 Jul 30.

15.

Identification and characterization of a novel small-molecule inhibitor of β-catenin signaling.

Delgado ER, Yang J, So J, Leimgruber S, Kahn M, Ishitani T, Shin D, Mustata Wilson G, Monga SP.

Am J Pathol. 2014 Jul;184(7):2111-22. doi: 10.1016/j.ajpath.2014.04.002. Epub 2014 May 10.

16.

Wnt/Dkk negative feedback regulates sensory organ size in zebrafish.

Wada H, Ghysen A, Asakawa K, Abe G, Ishitani T, Kawakami K.

Curr Biol. 2013 Aug 19;23(16):1559-65. doi: 10.1016/j.cub.2013.06.035. Epub 2013 Jul 25.

17.

Nemo-like kinase, a multifaceted cell signaling regulator.

Ishitani T, Ishitani S.

Cell Signal. 2013 Jan;25(1):190-7. doi: 10.1016/j.cellsig.2012.09.017. Epub 2012 Sep 18. Review.

PMID:
23000342
18.

Visualization and exploration of Tcf/Lef function using a highly responsive Wnt/β-catenin signaling-reporter transgenic zebrafish.

Shimizu N, Kawakami K, Ishitani T.

Dev Biol. 2012 Oct 1;370(1):71-85. doi: 10.1016/j.ydbio.2012.07.016. Epub 2012 Jul 25.

19.

Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning.

Kim WT, Kim H, Katanaev VL, Joon Lee S, Ishitani T, Cha B, Han JK, Jho EH.

EMBO J. 2012 Aug 15;31(16):3384-97. doi: 10.1038/emboj.2012.181. Epub 2012 Jul 6.

20.

Synbiotic therapy reduces the pathological gram-negative rods caused by an increased acetic acid concentration in the gut.

Hayakawa M, Asahara T, Ishitani T, Okamura A, Nomoto K, Gando S.

Dig Dis Sci. 2012 Oct;57(10):2642-9. Epub 2012 May 11.

21.

Context-dependent dual and opposite roles of nemo-like kinase in the Wnt/β-catenin signaling.

Ishitani T.

Cell Cycle. 2012 May 1;11(9):1743-5. doi: 10.4161/cc.20183. Epub 2012 May 1. No abstract available.

22.

DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish.

Hozumi S, Hirabayashi R, Yoshizawa A, Ogata M, Ishitani T, Tsutsumi M, Kuroiwa A, Itoh M, Kikuchi Y.

PLoS One. 2012;7(3):e33675. doi: 10.1371/journal.pone.0033675. Epub 2012 Mar 19.

23.

[Protein kinase NLK, that fine-tunes the activity of multiple intracellular signaling pathways].

Ishitani T.

Seikagaku. 2012 Jan;84(1):39-42. Review. Japanese. No abstract available.

PMID:
22416471
24.

NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells.

Ota S, Ishitani S, Shimizu N, Matsumoto K, Itoh M, Ishitani T.

EMBO J. 2012 Apr 18;31(8):1904-15. doi: 10.1038/emboj.2012.46. Epub 2012 Feb 28.

25.

Zebrafish Dmrta2 regulates neurogenesis in the telencephalon.

Yoshizawa A, Nakahara Y, Izawa T, Ishitani T, Tsutsumi M, Kuroiwa A, Itoh M, Kikuchi Y.

Genes Cells. 2011 Nov;16(11):1097-109. doi: 10.1111/j.1365-2443.2011.01555.x.

26.

Cold exposure down-regulates zebrafish pigmentation.

Kulkeaw K, Ishitani T, Kanemaru T, Ivanovski O, Nakagawa M, Mizuochi C, Horio Y, Sugiyama D.

Genes Cells. 2011 Apr;16(4):358-67. doi: 10.1111/j.1365-2443.2011.01498.x. Epub 2011 Mar 11.

27.

Homodimerization of Nemo-like kinase is essential for activation and nuclear localization.

Ishitani S, Inaba K, Matsumoto K, Ishitani T.

Mol Biol Cell. 2011 Jan 15;22(2):266-77. doi: 10.1091/mbc.E10-07-0605. Epub 2010 Nov 30.

28.

Analysis of hypoxia in the western interior parts of the Ariake Sea, Japan, using a box model.

Koriyama M, Seguchi M, Ishitani T, Isnansetyo A.

Environ Monit Assess. 2011 Aug;179(1-4):65-80. doi: 10.1007/s10661-010-1719-6. Epub 2010 Oct 2.

PMID:
20886287
29.

Mib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions.

Yamamoto M, Morita R, Mizoguchi T, Matsuo H, Isoda M, Ishitani T, Chitnis AB, Matsumoto K, Crump JG, Hozumi K, Yonemura S, Kawakami K, Itoh M.

Development. 2010 Aug 1;137(15):2527-37. doi: 10.1242/dev.051011. Epub 2010 Jun 23.

30.

Delta1 family members are involved in filopodial actin formation and neuronal cell migration independent of Notch signaling.

Sugiyama K, Nishide K, Matsuo H, Okigawa S, Okano M, Ishitani T, Matsumoto K, Itoh M.

Biochem Biophys Res Commun. 2010 Jul 16;398(1):118-24. doi: 10.1016/j.bbrc.2010.06.047. Epub 2010 Jun 15.

PMID:
20558143
31.

KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

Tsukada Y, Ishitani T, Nakayama KI.

Genes Dev. 2010 Mar 1;24(5):432-7. doi: 10.1101/gad.1864410.

32.

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex.

Ishitani T, Hirao T, Suzuki M, Isoda M, Ishitani S, Harigaya K, Kitagawa M, Matsumoto K, Itoh M.

Nat Cell Biol. 2010 Mar;12(3):278-85. doi: 10.1038/ncb2028. Epub 2010 Jan 31.

PMID:
20118921
33.

Cold exposure down-regulates zebrafish hematopoiesis.

Kulkeaw K, Ishitani T, Kanemaru T, Fucharoen S, Sugiyama D.

Biochem Biophys Res Commun. 2010 Apr 16;394(4):859-64. doi: 10.1016/j.bbrc.2010.01.047. Epub 2010 Jan 25.

PMID:
20100463
34.

Characterization of kidney marrow in zebrafish (Danio rerio) by using a new surgical technique.

Ivanovski O, Kulkeaw K, Nakagawa M, Sasaki T, Mizuochi Ch, Horio Y, Ishitani T, Sugiyama D.

Prilozi. 2009 Dec;30(2):71-80.

PMID:
20087250
35.

Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase.

Ohnishi E, Goto T, Sato A, Kim MS, Iemura S, Ishitani T, Natsume T, Ohnishi J, Shibuya H.

Mol Cell Biol. 2010 Feb;30(3):675-83. doi: 10.1128/MCB.00576-09. Epub 2009 Nov 23.

36.

Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin.

Ishitani T, Ishitani S, Matsumoto K, Itoh M.

J Neurochem. 2009 Dec;111(5):1104-18. doi: 10.1111/j.1471-4159.2009.06400.x. Epub 2009 Oct 16.

37.

Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression.

Lee W, Swarup S, Chen J, Ishitani T, Verheyen EM.

Development. 2009 Jan;136(2):241-51. doi: 10.1242/dev.025460. Epub 2008 Dec 15.

38.

Simulation study on image contrast and spatial resolution in helium ion microscope.

Inai K, Ohya K, Ishitani T.

J Electron Microsc (Tokyo). 2007 Oct;56(5):163-9. Epub 2007 Nov 6.

PMID:
17989086
39.

Evaluation of both image resolution and contrast-to-noise ratio in scanning electron microscopy.

Ishitani T, Sato M.

J Electron Microsc (Tokyo). 2007 Aug;56(4):145-51. Epub 2007 Oct 31.

PMID:
17977979
40.
41.

Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability.

Ishitani T, Matsumoto K, Chitnis AB, Itoh M.

Nat Cell Biol. 2005 Nov;7(11):1106-12.

PMID:
16228014
42.

Influence of random noise on the contrast-to-gradient image resolution in scanning electron microscopy.

Ishitani T, Kamiya C, Sato M.

J Electron Microsc (Tokyo). 2005 Apr;54(2):85-97. Epub 2005 May 24.

PMID:
15914495
43.

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation.

Kojima H, Sasaki T, Ishitani T, Iemura S, Zhao H, Kaneko S, Kunimoto H, Natsume T, Matsumoto K, Nakajima K.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4524-9. Epub 2005 Mar 11.

44.

A method for multidirectional TEM observation of a specific site at atomic resolution.

Kamino T, Yaguchi T, Konno M, Ohnishi T, Ishitani T.

J Electron Microsc (Tokyo). 2004;53(6):583-8.

PMID:
15582970
45.

Application of a FIB-STEM system for 3D observation of a resin-embedded yeast cell.

Kamino T, Yaguchi T, Ohnishi T, Ishitani T, Osumi M.

J Electron Microsc (Tokyo). 2004;53(5):563-6.

PMID:
15582966
46.

Evaluation of TEM samples of an Mg-Al alloy prepared using FIB milling at the operating voltages of 10 kV and 40 kV.

Kamino T, Yaguchi T, Kuroda Y, Ohnishi T, Ishitani T, Miyahara Y, Horita Z.

J Electron Microsc (Tokyo). 2004;53(5):459-63.

PMID:
15582947
47.

Improvements in performance of focused ion beam cross-sectioning: aspects of ion-sample interaction.

Ishitani T, Umemura K, Ohnishi T, Yaguchi T, Kamino T.

J Electron Microsc (Tokyo). 2004;53(5):443-9.

PMID:
15582945
48.
49.

Monte Carlo simulation of topographic contrast in scanning ion microscope.

Ohya K, Ishitani T.

J Electron Microsc (Tokyo). 2004;53(3):229-35.

PMID:
15332649
50.

Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.

Kanei-Ishii C, Ninomiya-Tsuji J, Tanikawa J, Nomura T, Ishitani T, Kishida S, Kokura K, Kurahashi T, Ichikawa-Iwata E, Kim Y, Matsumoto K, Ishii S.

Genes Dev. 2004 Apr 1;18(7):816-29.

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