Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 284


Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice.

Shimizu S, Ishino Y, Takeda T, Tohyama M, Miyata S.

Evid Based Complement Alternat Med. 2019 Nov 3;2019:9475384. doi: 10.1155/2019/9475384. eCollection 2019.


Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations.

Maruyama K, Imai H, Kawamura M, Ishino S, Ishino Y, Ito K, Uchiumi T.

Sci Rep. 2019 Oct 14;9(1):14761. doi: 10.1038/s41598-019-51266-x.


Pol B, a Family B DNA Polymerase, in Thermococcus kodakarensis is Important for DNA Repair, but not DNA Replication.

Kushida T, Narumi I, Ishino S, Ishino Y, Fujiwara S, Imanaka T, Higashibata H.

Microbes Environ. 2019 Sep 25;34(3):316-326. doi: 10.1264/jsme2.ME19075. Epub 2019 Jul 27.


In Vivo Single-Cell Genotyping of Mouse Cortical Neurons Transfected with CRISPR/Cas9.

Steinecke A, Kurabayashi N, Hayano Y, Ishino Y, Taniguchi H.

Cell Rep. 2019 Jul 9;28(2):325-331.e4. doi: 10.1016/j.celrep.2019.06.038.


A Preliminary Metagenome Analysis Based on a Combination of Protein Domains.

Igarashi Y, Mori D, Mitsuyama S, Yoshitake K, Ono H, Watanabe T, Taniuchi Y, Sakami T, Kuwata A, Kobayashi T, Ishino Y, Watabe S, Gojobori T, Asakawa S.

Proteomes. 2019 Apr 29;7(2). pii: E19. doi: 10.3390/proteomes7020019.


Modeling and Validation of Vertical Direction Force Estimation with a Three-Dimensional Force Measurement Instrument Based on a Zero-Compliance Mechanism.

Nahiyan MHA, Mizuno T, Takasaki M, Ishino Y, Hara M, Yamaguchi D.

Sensors (Basel). 2019 Feb 15;19(4). pii: E799. doi: 10.3390/s19040799.


Replication protein A complex in Thermococcus kodakarensis interacts with DNA polymerases and helps their effective strand synthesis.

Nagata M, Ishino S, Yamagami T, Ishino Y.

Biosci Biotechnol Biochem. 2019 Apr;83(4):695-704. doi: 10.1080/09168451.2018.1559722. Epub 2018 Dec 22.


Elucidating functions of DP1 and DP2 subunits from the Thermococcus kodakarensis family D DNA polymerase.

Takashima N, Ishino S, Oki K, Takafuji M, Yamagami T, Matsuo R, Mayanagi K, Ishino Y.

Extremophiles. 2019 Jan;23(1):161-172. doi: 10.1007/s00792-018-1070-3. Epub 2018 Nov 30.


New archaeal viruses discovered by metagenomic analysis of viral communities in enrichment cultures.

Liu Y, Brandt D, Ishino S, Ishino Y, Koonin EV, Kalinowski J, Krupovic M, Prangishvili D.

Environ Microbiol. 2019 Jun;21(6):2002-2014. doi: 10.1111/1462-2920.14479. Epub 2019 Jan 8.


Direct visualization of DNA baton pass between replication factors bound to PCNA.

Mayanagi K, Ishino S, Shirai T, Oyama T, Kiyonari S, Kohda D, Morikawa K, Ishino Y.

Sci Rep. 2018 Nov 1;8(1):16209. doi: 10.1038/s41598-018-34176-2.


A Novel Three-Step Approach for Secure Splenectomy During Laparoscopic Total Gastrectomy for Gastric Cancer.

Matsubara H, Kinjo Y, Fukugaki A, Iwamoto M, Ohara K, Ishino Y, Ochi S, Matsumoto T, Matsushita T, Satoh S.

J Gastrointest Surg. 2019 May;23(5):1082-1083. doi: 10.1007/s11605-018-4010-8. Epub 2018 Oct 26.


The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG.

Shiraishi M, Ishino S, Heffernan M, Cann I, Ishino Y.

Sci Rep. 2018 Oct 25;8(1):15791. doi: 10.1038/s41598-018-34000-x.


Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication.

Ishino S, Skouloubris S, Kudo H, l'Hermitte-Stead C, Es-Sadik A, Lambry JC, Ishino Y, Myllykallio H.

Nucleic Acids Res. 2018 Jul 6;46(12):6206-6217. doi: 10.1093/nar/gky460.


NDE1 positively regulates oligodendrocyte morphological differentiation.

Shimizu S, Ishino Y, Tohyama M, Miyata S.

Sci Rep. 2018 May 16;8(1):7644. doi: 10.1038/s41598-018-25898-4.


Two Family B DNA Polymerases From Aeropyrum pernix, Based on Revised Translational Frames.

Daimon K, Ishino S, Imai N, Nagumo S, Yamagami T, Matsukawa H, Ishino Y.

Front Mol Biosci. 2018 Apr 16;5:37. doi: 10.3389/fmolb.2018.00037. eCollection 2018.


Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus.

Miyazono KI, Ishino S, Makita N, Ito T, Ishino Y, Tanokura M.

Nucleic Acids Res. 2018 May 18;46(9):4807-4818. doi: 10.1093/nar/gky261.


History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology.

Ishino Y, Krupovic M, Forterre P.

J Bacteriol. 2018 Mar 12;200(7). pii: e00580-17. doi: 10.1128/JB.00580-17. Print 2018 Apr 1. Review.


Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef.

Nagata M, Ishino S, Yamagami T, Simons JR, Kanai T, Atomi H, Ishino Y.

Sci Rep. 2017 Dec 5;7(1):16949. doi: 10.1038/s41598-017-17306-0.


The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis.

Nagata M, Ishino S, Yamagami T, Ogino H, Simons JR, Kanai T, Atomi H, Ishino Y.

Nucleic Acids Res. 2017 Oct 13;45(18):10693-10705. doi: 10.1093/nar/gkx740.


Regional Cellular Environment Shapes Phenotypic Variations of Hippocampal and Neocortical Chandelier Cells.

Ishino Y, Yetman MJ, Sossi SM, Steinecke A, Hayano Y, Taniguchi H.

J Neurosci. 2017 Oct 11;37(41):9901-9916. doi: 10.1523/JNEUROSCI.0047-17.2017. Epub 2017 Sep 14.


Neocortical Chandelier Cells Developmentally Shape Axonal Arbors through Reorganization but Establish Subcellular Synapse Specificity without Refinement.

Steinecke A, Hozhabri E, Tapanes S, Ishino Y, Zeng H, Kamasawa N, Taniguchi H.

eNeuro. 2017 May 12;4(3). pii: ENEURO.0057-17.2017. doi: 10.1523/ENEURO.0057-17.2017. eCollection 2017 May-Jun.


Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island.

Antranikian G, Suleiman M, Schäfers C, Adams MWW, Bartolucci S, Blamey JM, Birkeland NK, Bonch-Osmolovskaya E, da Costa MS, Cowan D, Danson M, Forterre P, Kelly R, Ishino Y, Littlechild J, Moracci M, Noll K, Oshima T, Robb F, Rossi M, Santos H, Schönheit P, Sterner R, Thauer R, Thomm M, Wiegel J, Stetter KO.

Extremophiles. 2017 Jul;21(4):733-742. doi: 10.1007/s00792-017-0938-y. Epub 2017 May 10.


Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.

Jiang W, Ishino Y, Hashimoto H, Keino-Masu K, Masu M, Uchimura K, Kadomatsu K, Yoshimura T, Ikenaka K.

Dev Neurosci. 2017;39(5):361-374. doi: 10.1159/000464284. Epub 2017 May 11.


A Novel Type of Polyhedral Viruses Infecting Hyperthermophilic Archaea.

Liu Y, Ishino S, Ishino Y, Pehau-Arnaudet G, Krupovic M, Prangishvili D.

J Virol. 2017 Jun 9;91(13). pii: e00589-17. doi: 10.1128/JVI.00589-17. Print 2017 Jul 1.


The RecJ2 protein in the thermophilic archaeon Thermoplasma acidophilum is a 3'-5' exonuclease that associates with a DNA replication complex.

Ogino H, Ishino S, Kohda D, Ishino Y.

J Biol Chem. 2017 May 12;292(19):7921-7931. doi: 10.1074/jbc.M116.767921. Epub 2017 Mar 16.


Exonuclease processivity of archaeal replicative DNA polymerase in association with PCNA is expedited by mismatches in DNA.

Yoda T, Tanabe M, Tsuji T, Yoda T, Ishino S, Shirai T, Ishino Y, Takeyama H, Nishida H.

Sci Rep. 2017 Mar 16;7:44582. doi: 10.1038/srep44582.


A functional endonuclease Q exists in the bacterial domain: identification and characterization of endonuclease Q from Bacillus pumilus.

Shiraishi M, Ishino S, Cann I, Ishino Y.

Biosci Biotechnol Biochem. 2017 May;81(5):931-937. doi: 10.1080/09168451.2016.1277946. Epub 2017 Jan 18.


Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease.

Nakae S, Hijikata A, Tsuji T, Yonezawa K, Kouyama KI, Mayanagi K, Ishino S, Ishino Y, Shirai T.

Structure. 2016 Nov 1;24(11):1960-1971. doi: 10.1016/j.str.2016.09.005. Epub 2016 Oct 20.


Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication.

Oyama T, Ishino S, Shirai T, Yamagami T, Nagata M, Ogino H, Kusunoki M, Ishino Y.

Nucleic Acids Res. 2016 Nov 2;44(19):9505-9517. Epub 2016 Sep 5.


[A Case of HER2-Positive Inflammatory Breast Cancer for Which Preoperative Chemotherapy with Pertuzumab Resulted in a Pathological Complete Response].

Konishi N, Iwanaga T, Ishino Y, Sugisawa A, Ide S, Kimura H, Iwata T, Watanabe H, Yokoe T, Ojima E, Ito H, Ikeda T, Tonouchi H, Shigemori C.

Gan To Kagaku Ryoho. 2016 Sep;43(9):1101-3. Japanese.


DJ-1 family Maillard deglycases prevent acrylamide formation.

Richarme G, Marguet E, Forterre P, Ishino S, Ishino Y.

Biochem Biophys Res Commun. 2016 Sep 23;478(3):1111-6. doi: 10.1016/j.bbrc.2016.08.077. Epub 2016 Aug 13.


PCNA is involved in the EndoQ-mediated DNA repair process in Thermococcales.

Shiraishi M, Ishino S, Yoshida K, Yamagami T, Cann I, Ishino Y.

Sci Rep. 2016 May 6;6:25532. doi: 10.1038/srep25532.


Identification of a mismatch-specific endonuclease in hyperthermophilic Archaea.

Ishino S, Nishi Y, Oda S, Uemori T, Sagara T, Takatsu N, Yamagami T, Shirai T, Ishino Y.

Nucleic Acids Res. 2016 Apr 20;44(7):2977-86. doi: 10.1093/nar/gkw153. Epub 2016 Mar 21.


Keratan Sulfate Regulates the Switch from Motor Neuron to Oligodendrocyte Generation During Development of the Mouse Spinal Cord.

Hashimoto H, Ishino Y, Jiang W, Yoshimura T, Takeda-Uchimura Y, Uchimura K, Kadomatsu K, Ikenaka K.

Neurochem Res. 2016 Feb;41(1-2):450-62. doi: 10.1007/s11064-016-1861-9. Epub 2016 Feb 11.


Mutation of the gene encoding the ribonuclease P RNA in the hyperthermophilic archaeon Thermococcus kodakarensis causes decreased growth rate and impaired processing of tRNA precursors.

Ueda T, Ishino S, Suematsu K, Nakashima T, Kakuta Y, Kawarabayasi Y, Ishino Y, Kimura M.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):660-5. doi: 10.1016/j.bbrc.2015.11.012. Epub 2015 Nov 10.


From Structure-Function Analyses to Protein Engineering for Practical Applications of DNA Ligase.

Tanabe M, Ishino Y, Nishida H.

Archaea. 2015 Oct 5;2015:267570. doi: 10.1155/2015/267570. eCollection 2015. Review.


A longer finger-subdomain of family A DNA polymerases found by metagenomic analysis strengthens DNA binding and primer extension abilities.

Yamagami T, Matsukawa H, Tsunekawa S, Kawarabayasi Y, Ishino S, Ishino Y.

Gene. 2016 Feb 1;576(2 Pt 1):690-5. doi: 10.1016/j.gene.2015.10.030. Epub 2015 Oct 22.


Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I.

Miyazono K, Ishino S, Tsutsumi K, Ito T, Ishino Y, Tanokura M.

Nucleic Acids Res. 2015 Aug 18;43(14):7122-36. doi: 10.1093/nar/gkv654. Epub 2015 Jul 2.


Guanine nucleotide exchange factor 2 for Rab5 proteins coordinated with GLUP6/GEF regulates the intracellular transport of the proglutelin from the Golgi apparatus to the protein storage vacuole in rice endosperm.

Wen L, Fukuda M, Sunada M, Ishino S, Ishino Y, Okita TW, Ogawa M, Ueda T, Kumamaru T.

J Exp Bot. 2015 Oct;66(20):6137-47. doi: 10.1093/jxb/erv325. Epub 2015 Jul 1.


EndoQ and EndoV work individually for damaged DNA base repair in Pyrococcus furiosus.

Ishino S, Makita N, Shiraishi M, Yamagami T, Ishino Y.

Biochimie. 2015 Nov;118:264-9. doi: 10.1016/j.biochi.2015.06.015. Epub 2015 Jun 24.


The Dorsoventral Boundary of the Germinal Zone is a Specialized Niche for the Generation of Cortical Oligodendrocytes during a Restricted Temporal Window.

Naruse M, Ishino Y, Kumar A, Ono K, Takebayashi H, Yamaguchi M, Ishizaki Y, Ikenaka K, Hitoshi S.

Cereb Cortex. 2016 Jun;26(6):2800-2810. doi: 10.1093/cercor/bhv141. Epub 2015 Jun 23.


DNA repair in hyperthermophilic and hyperradioresistant microorganisms.

Ishino Y, Narumi I.

Curr Opin Microbiol. 2015 Jun;25:103-12. doi: 10.1016/j.mib.2015.05.010. Epub 2015 Jun 8. Review.


Functional role of the C-terminal tail of the archaeal ribosomal stalk in recruitment of two elongation factors to the sarcin/ricin loop of 23S rRNA.

Imai H, Miyoshi T, Murakami R, Ito K, Ishino Y, Uchiumi T.

Genes Cells. 2015 Jul;20(7):613-24. doi: 10.1111/gtc.12256. Epub 2015 Jun 2.


An optimized Npro-based method for the expression and purification of intrinsically disordered proteins for an NMR study.

Goda N, Matsuo N, Tenno T, Ishino S, Ishino Y, Fukuchi S, Ota M, Hiroaki H.

Intrinsically Disord Proteins. 2015 Feb 23;3(1):e1011004. doi: 10.1080/21690707.2015.1011004. eCollection 2015.


A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus.

Shiraishi M, Ishino S, Yamagami T, Egashira Y, Kiyonari S, Ishino Y.

Nucleic Acids Res. 2015 Mar 11;43(5):2853-63. doi: 10.1093/nar/gkv121. Epub 2015 Feb 18.


Disordered interdomain region of Gins is important for functional tetramer formation to stimulate MCM helicase in Thermoplasma acidophilum.

Ogino H, Ishino S, Oyama T, Kohda D, Ishino Y.

Biosci Biotechnol Biochem. 2015;79(3):432-8. doi: 10.1080/09168451.2014.982503. Epub 2014 Nov 24.


Mutant Taq DNA polymerases with improved elongation ability as a useful reagent for genetic engineering.

Yamagami T, Ishino S, Kawarabayasi Y, Ishino Y.

Front Microbiol. 2014 Sep 3;5:461. doi: 10.3389/fmicb.2014.00461. eCollection 2014.


DNA polymerases as useful reagents for biotechnology - the history of developmental research in the field.

Ishino S, Ishino Y.

Front Microbiol. 2014 Aug 29;5:465. doi: 10.3389/fmicb.2014.00465. eCollection 2014. Review.


Preoperative C-reactive protein and operative blood loss predict poor prognosis in patients with gastric cancer after laparoscopy-assisted gastrectomy.

Ishino Y, Saigusa S, Ohi M, Yasuda H, Tanaka K, Toiyama Y, Mohri Y, Kusunoki M.

Asian J Endosc Surg. 2014 Nov;7(4):287-94. doi: 10.1111/ases.12126. Epub 2014 Aug 14.


Supplemental Content

Loading ...
Support Center