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Radiotherapy alone for stage IE ocular adnexal mucosa-associated lymphoid tissue lymphomas: long-term results.

Niwa M, Ishikura S, Tatekawa K, Takama N, Miyakawa A, Kubota T, Kato E, Shibamoto Y.

Radiat Oncol. 2020 Jan 30;15(1):25. doi: 10.1186/s13014-020-1477-8.


Single-arm confirmatory trial of postoperative concurrent chemoradiotherapy using intensity modulated radiation therapy for patients with high-risk uterine cervical cancer: Japan Clinical Oncology Group study (JCOG1402).

Murakami N, Isohashi F, Hasumi Y, Kasamatsu T, Okamoto H, Nakamura K, Shibata T, Ito Y, Ishikura S, Nishimura Y, Yaegashi N, Toita T.

Jpn J Clin Oncol. 2019 Sep 1;49(9):881-885. doi: 10.1093/jjco/hyz098.


Zfat Is Indispensable for the Development of Erythroid Cells in the Fetal Liver.

Doi K, Tsunoda T, Koyanagi M, Tanaka Y, Yamano S, Fujikane A, Nishi K, Ishikura S, Shirasawa S.

Anticancer Res. 2019 Aug;39(8):4495-4502. doi: 10.21873/anticanres.13625.


Dummy-run for standardizing plan quality of intensity-modulated radiotherapy for postoperative uterine cervical cancer: Japan Clinical Oncology Group study (JCOG1402).

Okamoto H, Murakami N, Isohashi F, Kasamatsu T, Hasumi Y, Iijima K, Nishioka S, Nakamura S, Nakamura M, Nishio T, Igaki H, Nakayama Y, Itami J, Ishikura S, Nishimura Y, Toita T.

Radiat Oncol. 2019 Jul 29;14(1):133. doi: 10.1186/s13014-019-1340-y.


Liver phantom design and dosimetric verification in participating institutions for a proton beam therapy in patients with resectable hepatocellular carcinoma: Japan Clinical Oncology Group trial (JCOG1315C).

Nishio T, Tachibana H, Kase Y, Hotta K, Nakamura M, Tamura M, Terunuma T, Toshito T, Yamashita H, Ishikura S, Fuji H, Akimoto T, Nishimura Y.

Radiother Oncol. 2019 Nov;140:98-104. doi: 10.1016/j.radonc.2019.06.005. Epub 2019 Jun 29.


Long-term results of intensity-modulated radiotherapy with three dose-fractionation regimens for localized prostate cancer.

Takemoto S, Shibamoto Y, Sugie C, Manabe Y, Yanagi T, Iwata H, Murai T, Ishikura S.

J Radiat Res. 2019 Mar 1;60(2):221-227. doi: 10.1093/jrr/rry089.


Final report of survival and late toxicities in the Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer (JCOG0702).

Onimaru R, Onishi H, Ogawa G, Hiraoka M, Ishikura S, Karasawa K, Matsuo Y, Kokubo M, Shioyama Y, Matsushita H, Ito Y, Shirato H.

Jpn J Clin Oncol. 2018 Dec 1;48(12):1076-1082. doi: 10.1093/jjco/hyy141.


An end-to-end postal audit test to examine the coincidence between the imaging isocenter and treatment beam isocenter of the IGRT linac system for Japan Clinical Oncology Group (JCOG) clinical trials.

Kumazaki Y, Ozawa S, Nakamura M, Kito S, Minemura T, Tachibana H, Nishio T, Ishikura S, Nishimura Y.

Phys Med. 2018 Sep;53:145-152. doi: 10.1016/j.ejmp.2018.08.010. Epub 2018 Sep 11.


Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.

Tsunoda T, Doi K, Ishikura S, Luo H, Nishi K, Matsuzaki H, Koyanagi M, Tanaka Y, Okamura T, Shirasawa S.

Int J Mol Med. 2018 Nov;42(5):2595-2603. doi: 10.3892/ijmm.2018.3806. Epub 2018 Aug 3.


Growth Suppression of Human Colorectal Cancer Cells with Mutated KRAS by 3-Deaza-cytarabine in 3D Floating Culture.

Luo H, Nishi K, Ishikura S, Swain A, Morishige N, Yazaki R, Ohshima T, Shirasawa S, Tsunoda T.

Anticancer Res. 2018 Jul;38(7):4247-4256. doi: 10.21873/anticanres.12721.


Chemoradiotherapy in Elderly Patients With Non-Small-Cell Lung Cancer: Long-Term Follow-Up of a Randomized Trial (JCOG0301).

Atagi S, Mizusawa J, Ishikura S, Takahashi T, Okamoto H, Tanaka H, Goto K, Nakagawa K, Harada M, Takeda Y, Nogami N, Fujita Y, Kasai T, Kishi K, Sawa T, Takeda K, Tomii K, Satouchi M, Seto T, Ohe Y.

Clin Lung Cancer. 2018 Sep;19(5):e619-e627. doi: 10.1016/j.cllc.2018.04.018. Epub 2018 May 5.


Recent research on the mechanism of heterosis is important for crop and vegetable breeding systems.

Fujimoto R, Uezono K, Ishikura S, Osabe K, Peacock WJ, Dennis ES.

Breed Sci. 2018 Mar;68(2):145-158. doi: 10.1270/jsbbs.17155. Epub 2018 Apr 12. Review.


Results of a multi-institutional, randomized, non-inferiority, phase III trial of accelerated fractionation versus standard fractionation in radiation therapy for T1-2N0M0 glottic cancer: Japan Clinical Oncology Group Study (JCOG0701).

Kodaira T, Kagami Y, Shibata T, Shikama N, Nishimura Y, Ishikura S, Nakamura K, Saito Y, Matsumoto Y, Teshima T, Ito Y, Akimoto T, Nakata K, Toshiyasu T, Nakagawa K, Nagata Y, Nishimura T, Uno T, Kataoka M, Yorozu A, Hiraoka M; Radiation Therapy Study Group of the Japan Clinical Oncology Group.

Ann Oncol. 2018 Apr 1;29(4):992-997. doi: 10.1093/annonc/mdy036.


Nimotuzumab combined with concurrent chemoradiotherapy in Japanese patients with esophageal cancer: A phase I study.

Kato K, Ura T, Koizumi W, Iwasa S, Katada C, Azuma M, Ishikura S, Nakao Y, Onuma H, Muro K.

Cancer Sci. 2018 Mar;109(3):785-793. doi: 10.1111/cas.13481. Epub 2018 Feb 15.


ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line.

Nishi K, Iwaihara Y, Tsunoda T, Doi K, Sakata T, Shirasawa S, Ishikura S.

Cell Death Dis. 2017 Dec 14;8(12):3218. doi: 10.1038/s41419-017-0006-7.


A virtual dosimetry audit - Towards transferability of gamma index analysis between clinical trial QA groups.

Hussein M, Clementel E, Eaton DJ, Greer PB, Haworth A, Ishikura S, Kry SF, Lehmann J, Lye J, Monti AF, Nakamura M, Hurkmans C, Clark CH; Global Quality Assurance of Radiation Therapy Clinical Trial Harmonisation Group.

Radiother Oncol. 2017 Dec;125(3):398-404. doi: 10.1016/j.radonc.2017.10.012.


Esophageal stenosis and the Glasgow Prognostic Score as independent factors of poor prognosis for patients with locally advanced unresectable esophageal cancer treated with chemoradiotherapy (exploratory analysis of JCOG0303).

Okuno T, Wakabayashi M, Kato K, Shinoda M, Katayama H, Igaki H, Tsubosa Y, Kojima T, Okabe H, Kimura Y, Kawano T, Kosugi S, Toh Y, Kato H, Nakamura K, Fukuda H, Ishikura S, Ando N, Kitagawa Y; Japan Esophageal Oncology Group/Japan Clinical Oncology Group.

Int J Clin Oncol. 2017 Dec;22(6):1042-1049. doi: 10.1007/s10147-017-1154-6. Epub 2017 Jul 17.


An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids.

Nishi K, Luo H, Nakabayashi K, Doi K, Ishikura S, Iwaihara Y, Yoshida Y, Tanisawa K, Arai T, Mori S, Sawabe M, Muramatsu M, Tanaka M, Sakata T, Shirasawa S, Tsunoda T.

Anticancer Res. 2017 Jul;37(7):3855-3862.


Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS.

Nishi K, Luo H, Ishikura S, Doi K, Iwaihara Y, Wills L, Baillie GS, Sakata T, Shirasawa S, Tsunoda T.

Anticancer Res. 2017 Jul;37(7):3833-3839.


Randomized phase II trial of weekly dose-intensive chemotherapy or amrubicin plus cisplatin chemotherapy following induction chemoradiotherapy for limited-disease small cell lung cancer (JCOG1011).

Sekine I, Harada H, Yamamoto N, Wakabayashi M, Murakami H, Goto K, Nogami N, Seto T, Oshita F, Okamoto H, Tanaka H, Tamura T, Ishikura S, Ohe Y.

Lung Cancer. 2017 Jun;108:232-237. doi: 10.1016/j.lungcan.2017.04.002. Epub 2017 Apr 4.


A phase I/II study on stereotactic body radiotherapy with real-time tumor tracking using CyberKnife based on the Monte Carlo algorithm for lung tumors.

Iwata H, Ishikura S, Murai T, Iwabuchi M, Inoue M, Tatewaki K, Ohta S, Yokota N, Shibamoto Y.

Int J Clin Oncol. 2017 Aug;22(4):706-714. doi: 10.1007/s10147-017-1123-0. Epub 2017 Apr 20.


A randomized Phase III trial of comparing two dose-fractionations stereotactic body radiotherapy (SBRT) for medically inoperable Stage IA non-small cell lung cancer or small lung lesions clinically diagnosed as primary lung cancer: Japan Clinical Oncology Group Study JCOG1408 (J-SBRT trial).

Kimura T, Nagata Y, Eba J, Ozawa S, Ishikura S, Shibata T, Ito Y, Hiraoka M, Nishimura Y; Radiation Oncology Study Group of the Japan Clinical Oncology Group.

Jpn J Clin Oncol. 2017 Mar;47(3):277-281. doi: 10.1093/jjco/hyw198. Epub 2017 Jan 9.


Robustness and efficiency in interconnected networks with changes in network assortativity.

Murakami M, Ishikura S, Kominami D, Shimokawa T, Murata M.

Appl Netw Sci. 2017;2(1):6. doi: 10.1007/s41109-017-0025-4. Epub 2017 Mar 11.


Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer (JCOG0702): Results for the group with PTV⩾100cc.

Onimaru R, Onishi H, Shibata T, Hiraoka M, Ishikura S, Karasawa K, Matsuo Y, Kokubo M, Shioyama Y, Matsushita H, Ito Y, Shirato H.

Radiother Oncol. 2017 Feb;122(2):281-285. doi: 10.1016/j.radonc.2016.11.022. Epub 2016 Dec 16.


Role of DNA methylation in hybrid vigor in Arabidopsis thaliana.

Kawanabe T, Ishikura S, Miyaji N, Sasaki T, Wu LM, Itabashi E, Takada S, Shimizu M, Takasaki-Yasuda T, Osabe K, Peacock WJ, Dennis ES, Fujimoto R.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6704-E6711. Epub 2016 Oct 7.


Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.

Ishikura S, Tsunoda T, Nakabayashi K, Doi K, Koyanagi M, Hayashi K, Kawai T, Tanaka Y, Iwaihara Y, Luo H, Nishi K, Okamura T, Shirasawa S.

Biochim Biophys Acta. 2016 Nov;1859(11):1398-1410. doi: 10.1016/j.bbagrm.2016.08.010. Epub 2016 Aug 31.


Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling.

Yuasa T, Amo-Shiinoki K, Ishikura S, Takahara M, Matsuoka T, Kaneto H, Kuroda A, Matsuhisa M, Hashida S.

Diabetologia. 2016 Dec;59(12):2711-2721. Epub 2016 Sep 30.


An on-site audit system for dosimetry credentialing of intensity-modulated radiotherapy in Japanese Clinical Oncology Group (JCOG) clinical trials.

Nakamura M, Minemura T, Ishikura S, Nishio T, Narita Y, Nishimura Y.

Phys Med. 2016 Aug;32(8):987-91. doi: 10.1016/j.ejmp.2016.07.002. Epub 2016 Jul 9.


In Regard to Nagata et al.

Nagata Y, Shibata T, Ishikura S.

Int J Radiat Oncol Biol Phys. 2016 Jul 15;95(4):1320. doi: 10.1016/j.ijrobp.2016.04.005. No abstract available.


The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway.

Ishikura S, Iwaihara Y, Tanaka Y, Luo H, Nishi K, Doi K, Koyanagi M, Okamura T, Tsunoda T, Shirasawa S.

J Biol Chem. 2016 Jul 15;291(29):15282-91. doi: 10.1074/jbc.M116.723734. Epub 2016 May 20.


Stereotactic body radiotherapy versus lobectomy for operable clinical stage IA lung adenocarcinoma: comparison of survival outcomes in two clinical trials with propensity score analysis (JCOG1313-A).

Eba J, Nakamura K, Mizusawa J, Suzuki K, Nagata Y, Koike T, Hiraoka M, Watanabe S, Ishikura S, Asamura H, Fukuda H; Lung Cancer Surgical Study Group and the Radiation Therapy Study Group of the Japan Clinical Oncology Group.

Jpn J Clin Oncol. 2016 Aug;46(8):748-53. doi: 10.1093/jjco/hyw058. Epub 2016 May 12.


Inter-institutional survival heterogeneity in chemoradiation therapy for esophageal cancer: exploratory analysis of the JCOG0303 study.

Hamamoto Y, Mizusawa J, Katayama H, Nakamura K, Kato K, Tsubosa Y, Ishikura S, Igaki H, Shinoda M, Fukuda H, Kitagawa Y, Ando N.

Jpn J Clin Oncol. 2016 Apr;46(4):389-92. doi: 10.1093/jjco/hyv211. Epub 2016 Jan 31.


Feasibility study of chemoradiotherapy followed by amrubicin and cisplatin for limited-disease small cell lung cancer.

Sekine I, Sumi M, Satouchi M, Tsujino K, Nishio M, Kozuka T, Niho S, Nihei K, Yamamoto N, Harada H, Ishikura S, Tamura T.

Cancer Sci. 2016 Mar;107(3):315-9. doi: 10.1111/cas.12875. Epub 2016 Feb 19.


Prospective Trial of Stereotactic Body Radiation Therapy for Both Operable and Inoperable T1N0M0 Non-Small Cell Lung Cancer: Japan Clinical Oncology Group Study JCOG0403.

Nagata Y, Hiraoka M, Shibata T, Onishi H, Kokubo M, Karasawa K, Shioyama Y, Onimaru R, Kozuka T, Kunieda E, Saito T, Nakagawa K, Hareyama M, Takai Y, Hayakawa K, Mitsuhashi N, Ishikura S.

Int J Radiat Oncol Biol Phys. 2015 Dec 1;93(5):989-96. doi: 10.1016/j.ijrobp.2015.07.2278. Epub 2015 Nov 11.


Structure of RizA, an L-amino-acid ligase from Bacillus subtilis.

Kagawa W, Arai T, Ishikura S, Kino K, Kurumizaka H.

Acta Crystallogr F Struct Biol Commun. 2015 Sep;71(Pt 9):1125-30. doi: 10.1107/S2053230X15012698. Epub 2015 Aug 25.


A questionnaire-based survey on 3D image-guided brachytherapy for cervical cancer in Japan: advances and obstacles.

Ohno T, Toita T, Tsujino K, Uchida N, Hatano K, Nishimura T, Ishikura S.

J Radiat Res. 2015 Nov;56(6):897-903. doi: 10.1093/jrr/rrv047. Epub 2015 Aug 11.


Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer with PTV<100 cc using a continual reassessment method (JCOG0702).

Onimaru R, Shirato H, Shibata T, Hiraoka M, Ishikura S, Karasawa K, Matsuo Y, Kokubo M, Shioyama Y, Matsushita H, Ito Y, Onishi H.

Radiother Oncol. 2015 Aug;116(2):276-80. doi: 10.1016/j.radonc.2015.07.008. Epub 2015 Jul 29.


Establishment of a Three-dimensional Floating Cell Culture System for Screening Drugs Targeting KRAS-mediated Signaling Molecules.

Tsunoda T, Ishikura S, Doi K, Iwaihara Y, Hidesima H, Luo H, Hirose Y, Shirasawa S.

Anticancer Res. 2015 Aug;35(8):4453-9.


Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells.

Iwaihara Y, Ishikura S, Doi K, Tsunoda T, Fujimoto T, Okamura T, Shirasawa S.

Anticancer Res. 2015 Aug;35(8):4419-23.


A new two-step accurate CT-MRI fusion technique for post-implant prostate cancer.

Kunogi H, Hojo H, Wakumoto Y, Saito AI, Ishikura S, Yamashiro Y, Kuwatsuru R, Sasai K.

J Contemp Brachytherapy. 2015 Apr;7(2):117-21. doi: 10.5114/jcb.2015.51290. Epub 2015 Apr 30.


Dose calculation accuracies in whole breast radiotherapy treatment planning: a multi-institutional study.

Hatanaka S, Miyabe Y, Tohyama N, Kumazaki Y, Kurooka M, Okamoto H, Tachibana H, Kito S, Wakita A, Ohotomo Y, Ikagawa H, Ishikura S, Nozaki M, Kagami Y, Hiraoka M, Nishio T.

Radiol Phys Technol. 2015 Jul;8(2):200-8. doi: 10.1007/s12194-015-0308-3. Epub 2015 Feb 3.


Randomized study of low-dose versus standard-dose chemoradiotherapy for unresectable esophageal squamous cell carcinoma (JCOG0303).

Shinoda M, Ando N, Kato K, Ishikura S, Kato H, Tsubosa Y, Minashi K, Okabe H, Kimura Y, Kawano T, Kosugi S, Toh Y, Nakamura K, Fukuda H; Japan Clinical Oncology Group.

Cancer Sci. 2015 Apr;106(4):407-12. doi: 10.1111/cas.12622. Epub 2015 Mar 9.


Global harmonization of quality assurance naming conventions in radiation therapy clinical trials.

Melidis C, Bosch WR, Izewska J, Fidarova E, Zubizarreta E, Ulin K, Ishikura S, Followill D, Galvin J, Haworth A, Besuijen D, Clark CH, Miles E, Aird E, Weber DC, Hurkmans CW, Verellen D.

Int J Radiat Oncol Biol Phys. 2014 Dec 1;90(5):1242-9. doi: 10.1016/j.ijrobp.2014.08.348. Erratum in: Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):1115. Clark, Clark [corrected to Clark, Catharine H].


Definitive radiotherapy for head and neck squamous cell carcinoma: update and perspectives on the basis of EBM.

Kodaira T, Nishimura Y, Kagami Y, Ito Y, Shikama N, Ishikura S, Hiraoka M.

Jpn J Clin Oncol. 2015 Mar;45(3):235-43. doi: 10.1093/jjco/hyu209. Epub 2014 Dec 9. Review.


Zfat-deficient CD4⁺ CD8⁺ double-positive thymocytes are susceptible to apoptosis with deregulated activation of p38 and JNK.

Ishikura S, Ogawa M, Doi K, Matsuzaki H, Iwaihara Y, Tanaka Y, Tsunoda T, Hideshima H, Okamura T, Shirasawa S.

J Cell Biochem. 2015 Jan;116(1):149-57. doi: 10.1002/jcb.24954.


Toxicities of organs at risk in the mediastinal and hilar regions following stereotactic body radiotherapy for centrally located lung tumors.

Nishimura S, Takeda A, Sanuki N, Ishikura S, Oku Y, Aoki Y, Kunieda E, Shigematsu N.

J Thorac Oncol. 2014 Sep;9(9):1370-6. doi: 10.1097/JTO.0000000000000260.


Resveratrol induces luminal apoptosis of human colorectal cancer HCT116 cells in three-dimensional culture.

Tsunoda T, Ishikura S, Doi K, Matsuzaki H, Iwaihara Y, Shirasawa S.

Anticancer Res. 2014 Aug;34(8):4551-5.


The roles of ZFAT in thymocyte differentiation and homeostasis of peripheral naive T-cells.

Doi K, Ishikura S, Shirasawa S.

Anticancer Res. 2014 Aug;34(8):4489-95. Review.


Suppression of Tomato mosaic virus disease in tomato plants by deep ultraviolet irradiation using light-emitting diodes.

Matsuura S, Ishikura S.

Lett Appl Microbiol. 2014 Nov;59(5):457-63. doi: 10.1111/lam.12301. Epub 2014 Jul 14.


Association between parents' trust in mental health professionals and disengagement from psychiatric service within the first 6 months of initial treatment of schizophrenia.

Ishikura S, Yamasaki S, Ando S, Nishida A, Tanoue M, Niimura J, Asukai N, Okazaki Y.

Early Interv Psychiatry. 2015 Aug;9(4):335-8. doi: 10.1111/eip.12162. Epub 2014 Jun 22.


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