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Items: 1 to 50 of 3455

1.

Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode.

Fujimoto J, Kurasawa O, Takagi T, Liu X, Banno H, Kojima T, Asano Y, Nakamura A, Nambu T, Hata A, Ishii T, Sameshima T, Debori Y, Miyamoto M, Klein MG, Tjhen R, Sang BC, Levin I, Lane SW, Snell GP, Li K, Kefala G, Hoffman ID, Ding SC, Cary DR, Mizojiri R.

ACS Med Chem Lett. 2019 Sep 19;10(10):1498-1503. doi: 10.1021/acsmedchemlett.9b00400. eCollection 2019 Oct 10.

PMID:
31620240
2.

Changes in Radiographic Findings and Plantar Pressure Distribution Following Forefoot Reconstructive Surgery for Patients with Rheumatoid Arthritis.

Lee H, Ishikawa H, Shibuya T, Takai C, Nomura Y, Kobayashi D, Abe A, Otani H, Ito S, Nakazono K, Ryu K, Ishii T, Saito S, Abe K, Murasawa A.

Mod Rheumatol. 2019 Oct 15:1-22. doi: 10.1080/14397595.2019.1680094. [Epub ahead of print]

PMID:
31612762
3.

Short TRPM2 prevents the targeting of full-length TRPM2 to the surface transmembrane by hijacking to ER associated degradation.

Yamamoto S, Ishii T, Mikami R, Numata T, Shimizu S.

Biochem Biophys Res Commun. 2019 Oct 11. pii: S0006-291X(19)31954-0. doi: 10.1016/j.bbrc.2019.10.065. [Epub ahead of print]

PMID:
31610913
4.

CRISPR/Cas9-Based RGEN-ISL Allows the Simultaneous and Specific Visualization of Proteins, DNA Repeats, and Sites of DNA Replication.

Němečková A, Wäsch C, Schubert V, Ishii T, Hřibová E, Houben A.

Cytogenet Genome Res. 2019 Oct 12. doi: 10.1159/000502600. [Epub ahead of print]

PMID:
31610539
5.

Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease.

Mori S, Honda H, Ishii T, Yoshimura M, Sasagasako N, Suzuki SO, Taniwaki T, Iwaki T.

Neuropathology. 2019 Oct;39(5):358-367. doi: 10.1111/neup.12600. Epub 2019 Oct 9.

PMID:
31599037
6.

Assessment of genetic diversity and genetic structure of wild rice populations in Myanmar.

Shishido R, Akimoto M, Htut T, Sato T, Ishii T.

Breed Sci. 2019 Sep;69(3):471-477. doi: 10.1270/jsbbs.18165. Epub 2019 Jul 11.

7.

Two-photon absorption property of Cl-substituted diphenylacetylenes by optical-probing photoacoustic spectroscopy.

Ishii T, Ando S, Isozaki T, Takeuchi R, Kashihara W, Suzuki T.

J Chem Phys. 2019 Oct 7;151(13):134304. doi: 10.1063/1.5121505.

PMID:
31594351
8.

Clinical Usefulness of Endoscopy, Barium Fluoroscopy, and Chest Computed Tomography for the Correct Diagnosis of Achalasia.

Akaishi T, Nakano T, Machida T, Abe M, Takayama S, Koseki K, Kamei T, Fukudo S, Ishii T.

Intern Med. 2019 Oct 7. doi: 10.2169/internalmedicine.3612-19. [Epub ahead of print]

9.

A Nonsense SMAD3 Mutation in a Girl with Familial Thoracic Aortic Aneurysm and Dissection without Joint Abnormality.

Maeda Y, Takasawa K, Ishii T, Nagashima A, Mouri M, Kunieda J, Morisaki H, Ito T, Mori M, Kashimada K, Doi S, Morio T.

Cardiology. 2019 Oct 4:1-7. doi: 10.1159/000502972. [Epub ahead of print]

PMID:
31587008
10.

Ratio of diastolic to systolic blood pressure represents renal resistive index.

Akaishi T, Abe M, Miki T, Miki M, Funamizu Y, Ito S, Abe T, Ishii T.

J Hum Hypertens. 2019 Oct 4. doi: 10.1038/s41371-019-0264-1. [Epub ahead of print]

PMID:
31586124
11.

Freeze-Dried Platelet-Rich Plasma Induces Osteoblast Proliferation via Platelet-Derived Growth Factor Receptor-Mediated Signal Transduction.

Kinoshita H, Orita S, Inage K, Fujimoto K, Shiga Y, Abe K, Inoue M, Norimoto M, Umimura T, Ishii T, Yonemoto T, Kamoda H, Tsukanishi T, Suzuki M, Hirosawa N, Akazawa T, Ohtori S.

Asian Spine J. 2019 Oct 4. doi: 10.31616/asj.2019.0048. [Epub ahead of print]

12.

Perspectives on the Use of Ninjin'yoeito in Modern Medicine: A Review of Randomized Controlled Trials.

Takayama S, Arita R, Ohsawa M, Kikuchi A, Yasui H, Makino T, Motoo Y, Ishii T.

Evid Based Complement Alternat Med. 2019 Sep 2;2019:9590260. doi: 10.1155/2019/9590260. eCollection 2019. Review.

13.

Early postoperative inflammatory response by procedure types: stapler-based segmentectomy versus lobectomy.

Ishikawa Y, Kojima F, Ishii T, Yoshiyasu N, Ohde S, Bando T.

Gen Thorac Cardiovasc Surg. 2019 Sep 26. doi: 10.1007/s11748-019-01214-3. [Epub ahead of print]

PMID:
31559588
14.

In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN.

Ishii T, Ishikawa M, Fujimori K, Maeda T, Kushima I, Arioka Y, Mori D, Nakatake Y, Yamagata B, Nio S, Kato TA, Yang N, Wernig M, Kanba S, Mimura M, Ozaki N, Okano H.

eNeuro. 2019 Oct 17;6(5). pii: ENEURO.0403-18.2019. doi: 10.1523/ENEURO.0403-18.2019. Print 2019 Sep/Oct.

15.

Laparoscopic surgical management of a mature presacral teratoma: a case report.

Wang L, Hirano Y, Ishii T, Kondo H, Hara K, Ishikawa S, Okada T, Obara N, Yamaguchi S.

Surg Case Rep. 2019 Sep 18;5(1):144. doi: 10.1186/s40792-019-0702-x.

16.

Successful Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome with Chronic Febricula Using the Traditional Japanese Medicine Shosaikoto.

Numata T, Miura K, Akaishi T, Arita R, Ishizawa K, Saito N, Sasaki H, Kikuchi A, Takayama S, Tobita M, Ishii T.

Intern Med. 2019 Sep 18. doi: 10.2169/internalmedicine.3218-19. [Epub ahead of print]

17.

Suppression of Cerebral Ischemia/Reperfusion Injury by Efficient Release of Encapsulated Ifenprodil From Liposomes Under Weakly Acidic pH Conditions.

Kikuchi T, Fukuta T, Agato Y, Yanagida Y, Ishii T, Koide H, Shimizu K, Oku N, Asai T.

J Pharm Sci. 2019 Sep 11. pii: S0022-3549(19)30574-X. doi: 10.1016/j.xphs.2019.09.006. [Epub ahead of print]

PMID:
31520645
18.

Sensitivity and specificity of meningeal signs in patients with meningitis.

Akaishi T, Kobayashi J, Abe M, Ishizawa K, Nakashima I, Aoki M, Ishii T.

J Gen Fam Med. 2019 Jul 15;20(5):193-198. doi: 10.1002/jgf2.268. eCollection 2019 Sep.

19.

Sonic hedgehog enhances calcium oscillations in hippocampal astrocytes.

Adachi C, Kakinuma N, Jo S, Ishii T, Arai Y, Arai S, Kitaguchi T, Takeda S, Inoue T.

J Biol Chem. 2019 Sep 10. pii: jbc.RA119.007883. doi: 10.1074/jbc.RA119.007883. [Epub ahead of print]

20.

In vivo activation of PEGylated long circulating lipid nanoparticle to achieve efficient siRNA delivery and target gene knock down in solid tumors.

Sasayama Y, Hasegawa M, Taguchi E, Kubota K, Kuboyama T, Naoi T, Yabuuchi H, Shimai N, Asano M, Tokunaga A, Ishii T, Enokizono J.

J Control Release. 2019 Sep 7. pii: S0168-3659(19)30537-1. doi: 10.1016/j.jconrel.2019.09.004. [Epub ahead of print]

PMID:
31505222
21.

Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, Progress and Perspective.

Kuriyama S, Metoki H, Kikuya M, Obara T, Ishikuro M, Yamanaka C, Nagai M, Matsubara H, Kobayashi T, Sugawara J, Tamiya G, Hozawa A, Nakaya N, Tsuchiya N, Nakamura T, Narita A, Kogure M, Hirata T, Tsuji I, Nagami F, Fuse N, Arai T, Kawaguchi Y, Higuchi S, Sakaida M, Suzuki Y, Osumi N, Nakayama K, Ito K, Egawa S, Chida K, Kodama E, Kiyomoto H, Ishii T, Tsuboi A, Tomita H, Taki Y, Kawame H, Suzuki K, Ishii N, Ogishima S, Mizuno S, Takai-Igarashi T, Minegishi N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Tanabe O, Koshiba S, Hashizume H, Motohashi H, Tominaga T, Ito S, Tanno K, Sakata K, Shimizu A, Hitomi J, Sasaki M, Kinoshita K, Tanaka H, Kobayashi T, Kure S, Yaegashi N, Yamamoto M; Tohoku Medical Megabank Project Study Group .

Int J Epidemiol. 2019 Aug 25. pii: dyz169. doi: 10.1093/ije/dyz169. [Epub ahead of print] No abstract available.

PMID:
31504573
22.

Strong eigenstate thermalization within a generalized shell in noninteracting integrable systems.

Ishii T, Mori T.

Phys Rev E. 2019 Jul;100(1-1):012139. doi: 10.1103/PhysRevE.100.012139.

PMID:
31499917
23.

Activation through toll-like receptor 2 on group 2 innate lymphoid cells can induce asthmatic characteristics.

Ishii T, Muroi M, Horiguchi K, Tanamoto KI, Nagase T, Yamashita N.

Clin Exp Allergy. 2019 Sep 8. doi: 10.1111/cea.13490. [Epub ahead of print]

PMID:
31494992
24.

Three cases of free flap anastomoses to the descending genicular artery for knee joint trauma with severe soft tissue injury.

Kobayashi Y, Uchiyama Y, Ishii T, Nakajima D, Yanagisawa S, Saito I, Watanabe M.

J Orthop Sci. 2019 Aug 29. pii: S0949-2658(19)30253-2. doi: 10.1016/j.jos.2019.08.002. [Epub ahead of print] No abstract available.

PMID:
31474521
25.

An internal distraction device for midface distraction osteogenesis: The NAVID system type Z'gok.

Sakamoto Y, Sakamoto T, Ishii T, Kishi K.

J Plast Reconstr Aesthet Surg. 2019 Aug 8. pii: S1748-6815(19)30350-X. doi: 10.1016/j.bjps.2019.07.016. [Epub ahead of print]

PMID:
31473118
26.

Influence of renal function and demographic data on intrarenal Doppler ultrasonography.

Abe M, Akaishi T, Miki T, Miki M, Funamizu Y, Araya K, Ishizawa K, Takayama S, Takase K, Abe T, Ishii T, Ito S.

PLoS One. 2019 Aug 27;14(8):e0221244. doi: 10.1371/journal.pone.0221244. eCollection 2019.

27.

N-Heterocyclic Carbene-Catalyzed Radical Relay Enabling Vicinal Alkylacylation of Alkenes.

Ishii T, Ota K, Nagao K, Ohmiya H.

J Am Chem Soc. 2019 Sep 11;141(36):14073-14077. doi: 10.1021/jacs.9b07194. Epub 2019 Aug 28.

PMID:
31449757
28.

A Computational Approach to Explore and Identify Potential Herbal Inhibitors for the p21-activated kinase 1 (PAK1).

Shahinozzaman M, Ishii T, Ahmed S, Halim MA, Tawata S.

J Biomol Struct Dyn. 2019 Aug 25:1-21. doi: 10.1080/07391102.2019.1659855. [Epub ahead of print]

PMID:
31448698
29.

Consideration of gravity as a possible etiological factor in amyotrophic lateral sclerosis.

Akaishi T, Takahashi T, Abe M, Aoki M, Ishii T.

Med Hypotheses. 2019 Aug 17;132:109369. doi: 10.1016/j.mehy.2019.109369. [Epub ahead of print]

PMID:
31442918
30.

A Comparison of Radiographic Outcomes between 3D Preoperative Planning and Conventional Planning in the Osteosynthesis of Distal Radius Fractures.

Yoshii Y, Totoki Y, Tung WL, Akita K, Ishii T.

J Hand Surg Asian Pac Vol. 2019 Sep;24(3):303-310. doi: 10.1142/S2424835519500383.

PMID:
31438797
31.

Cytotoxic and anti-inflammatory resorcinol and alkylbenzoquinone derivatives from the leaves of Ardisia sieboldii.

Shahinozzaman M, Ishii T, Halim MA, Hossain MA, Islam MT, Tawata S.

Z Naturforsch C. 2019 Aug 22. pii: /j/znc.ahead-of-print/znc-2019-0114/znc-2019-0114.xml. doi: 10.1515/znc-2019-0114. [Epub ahead of print]

PMID:
31437126
32.

Synthesis of P- and N-doped carbon catalysts for the oxygen reduction reaction via controlled phosphoric acid treatment of folic acid.

Kobayashi R, Ishii T, Imashiro Y, Ozaki JI.

Beilstein J Nanotechnol. 2019 Jul 25;10:1497-1510. doi: 10.3762/bjnano.10.148. eCollection 2019.

33.

Smiling enemies: Young children better recall mean individuals who smile.

Meng X, Ishii T, Sugimoto K, Song R, Moriguchi Y, Watanabe K.

J Exp Child Psychol. 2019 Dec;188:104672. doi: 10.1016/j.jecp.2019.104672. Epub 2019 Aug 17.

PMID:
31430567
34.

Should Long-Term Follow-up Post-Mitochondrial Replacement be Left up to Physicians, Parents, or Offspring?

Ishii T.

New Bioeth. 2019 Aug 20:1-14. doi: 10.1080/20502877.2019.1654672. [Epub ahead of print]

PMID:
31429373
35.

Assessment of Bioabsorbable Hydroxyapatite for Secondary Bone Grafting in Unilateral Alveolar Clefts.

Sakamoto Y, Sakamoto T, Ishii T, Kishi K.

Cleft Palate Craniofac J. 2019 Aug 18:1055665619866372. doi: 10.1177/1055665619866372. [Epub ahead of print]

PMID:
31422680
36.

Antipsychotic-like effects of a novel phosphodiesterase 10A inhibitor T-251 in rodents.

Takakuwa M, Watanabe Y, Tanaka K, Ishii T, Kagaya K, Taniguchi H, Kotera J, Hashimoto K.

Pharmacol Biochem Behav. 2019 Oct;185:172757. doi: 10.1016/j.pbb.2019.172757. Epub 2019 Aug 9.

PMID:
31404565
37.

Refractory Takayasu arteritis successfully treated with rituximab: case-based review.

Mutoh T, Ishii T, Shirai T, Akita K, Kamogawa Y, Fujita Y, Sato H, Shirota Y, Fujii H, Harigae H.

Rheumatol Int. 2019 Nov;39(11):1989-1994. doi: 10.1007/s00296-019-04390-w. Epub 2019 Aug 6. Review.

PMID:
31388749
38.

CD45+CD326+ Cells are Predictive of Poor Prognosis in Non-Small Cell Lung Cancer Patients.

Ishizawa K, Yamanaka M, Saiki Y, Miyauchi E, Fukushige S, Akaishi T, Asao A, Mimori T, Saito R, Tojo Y, Yamashita R, Abe M, Sakurada A, Pham NA, Li M, Okada Y, Ishii T, Ishii N, Kobayashi S, Nagasaki M, Ichinose M, Tsao MS, Horii A.

Clin Cancer Res. 2019 Aug 5. doi: 10.1158/1078-0432.CCR-19-0545. [Epub ahead of print]

PMID:
31383733
39.

Possible interesting link between dipping status and morning surge for subclinical target organ damage in hypertension.

Tamura K, Waki K, Kawai Y, Ueda E, Ishii T, Wakui H.

J Clin Hypertens (Greenwich). 2019 Sep;21(9):1295-1297. doi: 10.1111/jch.13637. Epub 2019 Aug 3. No abstract available.

40.

Estimating the Prevalence of Transthyretin Amyloid Cardiomyopathy in a Large In-Hospital Database in Japan.

Winburn I, Ishii T, Sumikawa T, Togo K, Yasunaga H.

Cardiol Ther. 2019 Aug 2. doi: 10.1007/s40119-019-0142-5. [Epub ahead of print]

PMID:
31376091
41.

Clinical differentiation of acute appendicitis and right colonic diverticulitis: A case-control study.

Sasaki Y, Komatsu F, Kashima N, Sato T, Takemoto I, Kijima S, Maeda T, Ishii T, Miyazaki T, Honda Y, Shimada N, Urita Y.

World J Clin Cases. 2019 Jun 26;7(12):1393-1402. doi: 10.12998/wjcc.v7.i12.1393.

42.

Warped graphitic layers generated by oxidation of fullerene extraction residue and its oxygen reduction catalytic activity.

Takigami M, Kobayashi R, Ishii T, Imashiro Y, Ozaki JI.

Beilstein J Nanotechnol. 2019 Jul 12;10:1391-1400. doi: 10.3762/bjnano.10.137. eCollection 2019.

43.

Giant Protruding Nodular Fasciitis of the Anterior Chest Wall Clinically Mimicking a Soft Tissue Sarcoma.

Kinoshita H, Yonemoto T, Kamoda H, Hagiwara Y, Tsukanishi T, Orita S, Inage K, Hirosawa N, Ohtori S, Ishii T.

Case Rep Orthop. 2019 Jul 3;2019:4174985. doi: 10.1155/2019/4174985. eCollection 2019.

44.

The current status of the Transthyretin Amyloidosis Outcomes Survey (THAOS) in Japan.

Sekijima Y, Mundayat R, Ishii T, Ando Y.

Amyloid. 2019;26(sup1):61-62. doi: 10.1080/13506129.2019.1583182. No abstract available.

PMID:
31343365
45.

Patient profile with ATTR-FAP and evaluation of the safety and efficacy of tafamidis meglumine in Japan - interim analysis in post-marketing surveillance.

Ishii T, Sekijima Y, Ando Y.

Amyloid. 2019;26(sup1):45-46. doi: 10.1080/13506129.2019.1582508. No abstract available.

PMID:
31343289
46.

Effects of 5-aminolevulinic acid and sodium ferrous citrate on fibroblasts from individuals with mitochondrial diseases.

Shimura M, Nozawa N, Ogawa-Tominaga M, Fushimi T, Tajika M, Ichimoto K, Matsunaga A, Tsuruoka T, Kishita Y, Ishii T, Takahashi K, Tanaka T, Nakajima M, Okazaki Y, Ohtake A, Murayama K.

Sci Rep. 2019 Jul 22;9(1):10549. doi: 10.1038/s41598-019-46772-x.

47.

Association of specific metastatic organs with the prognosis and chemotherapeutic response in patients with advanced lung cancer.

Kanaji N, Tadokoro A, Watanabe N, Inoue T, Kadowaki N, Ishii T.

Respir Investig. 2019 Sep;57(5):472-480. doi: 10.1016/j.resinv.2019.06.004. Epub 2019 Jul 18.

PMID:
31327681
48.

The Effects of Fluvastatin on Indian Hedgehog Pathway in Endochondral Ossification.

Ishikawa M, Ishii T, Morikawa T, Iijima Y, Sueishi K.

Cartilage. 2019 Jul 22:1947603519862318. doi: 10.1177/1947603519862318. [Epub ahead of print]

PMID:
31327238
49.

Two ways of escaping from oxidative RNA damage: Selective degradation and cell death.

Ishii T, Sekiguchi M.

DNA Repair (Amst). 2019 Sep;81:102666. doi: 10.1016/j.dnarep.2019.102666. Epub 2019 Jul 8. Review.

PMID:
31326364
50.

Risk of SOFA Deterioration in Conservative Treatment for Emphysematous Pyelonephritis: Pitfalls of Current Trends in Therapeutics from Multicenter Clinical Experience.

Ozawa M, Ichiyanagi O, Fujita S, Naito S, Fukuhara H, Suenaga S, Takai S, Narisawa T, Hosoya N, Ishii T, Yamanobe T, Muto A, Suzuki H, Nishida H, Kato T, Tsuchiya N.

Curr Urol. 2019 May 10;12(3):134-141. doi: 10.1159/000489431.

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