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Items: 1 to 50 of 215

1.

ZBP1 governs the inflammasome-independent IL-1α and neutrophil inflammation that play a dual role in anti-influenza virus immunity.

Momota M, Lelliott P, Kubo A, Kusakabe T, Kobiyama K, Kuroda E, Imai Y, Akira S, Coban C, Ishii KJ.

Int Immunol. 2019 Oct 20. pii: dxz070. doi: 10.1093/intimm/dxz070. [Epub ahead of print]

PMID:
31630209
2.

Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor.

Ozasa K, Temizoz B, Kusakabe T, Kobari S, Momota M, Coban C, Ito S, Kobiyama K, Kuroda E, Ishii KJ.

Front Immunol. 2019 Sep 26;10:2212. doi: 10.3389/fimmu.2019.02212. eCollection 2019.

3.

Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis.

Kato T, Yasuda K, Matsushita K, Ishii KJ, Hirota S, Yoshimoto T, Shibahara H.

Front Immunol. 2019 Aug 22;10:2021. doi: 10.3389/fimmu.2019.02021. eCollection 2019.

4.

Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies.

Adachi Y, Tonouchi K, Nithichanon A, Kuraoka M, Watanabe A, Shinnakasu R, Asanuma H, Ainai A, Ohmi Y, Yamamoto T, Ishii KJ, Hasegawa H, Takeyama H, Lertmemongkolchai G, Kurosaki T, Ato M, Kelsoe G, Takahashi Y.

Nat Commun. 2019 Aug 28;10(1):3883. doi: 10.1038/s41467-019-11821-6.

5.

Antigen-specific Mucosal Immunity Regulates Development of Intestinal Bacteria-mediated Diseases.

Fujimoto K, Kawaguchi Y, Shimohigoshi M, Gotoh Y, Nakano Y, Usui Y, Hayashi T, Kimura Y, Uematsu M, Yamamoto T, Akeda Y, Rhee JH, Yuki Y, Ishii KJ, Crowe SE, Ernst PB, Kiyono H, Uematsu S.

Gastroenterology. 2019 Aug 21. pii: S0016-5085(19)41241-9. doi: 10.1053/j.gastro.2019.08.021. [Epub ahead of print]

PMID:
31445037
6.

Requirement for memory B cell activation in protection from heterologous influenza virus reinfection.

Leach S, Shinnakasu R, Adachi Y, Momota M, Makino-Okamura C, Yamamoto T, Ishii KJ, Fukuyama H, Takahashi Y, Kurosaki T.

Int Immunol. 2019 Jun 20. pii: dxz049. doi: 10.1093/intimm/dxz049. [Epub ahead of print]

PMID:
31231764
7.

BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses.

Nagatake T, Hirata SI, Koga T, Kuroda E, Kobari S, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J.

Mucosal Immunol. 2019 Sep;12(5):1082-1091. doi: 10.1038/s41385-019-0175-z. Epub 2019 May 29.

PMID:
31142830
8.

B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant.

Lee MSJ, Natsume-Kitatani Y, Temizoz B, Fujita Y, Konishi A, Matsuda K, Igari Y, Tsukui T, Kobiyama K, Kuroda E, Onishi M, Marichal T, Ise W, Inoue T, Kurosaki T, Mizuguchi K, Akira S, Ishii KJ, Coban C.

Eur J Immunol. 2019 Sep;49(9):1433-1440. doi: 10.1002/eji.201848084. Epub 2019 May 21.

PMID:
31087643
9.

Rapid Quantification of NETs In Vitro and in Whole Blood Samples by Imaging Flow Cytometry.

Lelliott PM, Momota M, Lee MSJ, Kuroda E, Iijima N, Ishii KJ, Coban C.

Cytometry A. 2019 May;95(5):565-578. doi: 10.1002/cyto.a.23767. Epub 2019 Apr 15.

PMID:
30985081
10.

STING agonists activate latently infected cells and enhance SIV-specific responses ex vivo in naturally SIV controlled cynomolgus macaques.

Yamamoto T, Kanuma T, Takahama S, Okamura T, Moriishi E, Ishii KJ, Terahara K, Yasutomi Y.

Sci Rep. 2019 Apr 11;9(1):5917. doi: 10.1038/s41598-019-42253-3.

11.

Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome.

Orimo T, Sasaki I, Hemmi H, Ozasa T, Fukuda-Ohta Y, Ohta T, Morinaka M, Kitauchi M, Yamaguchi T, Sato Y, Tanaka T, Hoshino K, Katayama KI, Fukuda S, Miyake K, Yamamoto M, Satoh T, Furukawa K, Kuroda E, Ishii KJ, Takeda K, Kaisho T.

Int Immunol. 2019 Sep 18;31(10):657-668. doi: 10.1093/intimm/dxz004.

12.

Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function.

Imanishi T, Unno M, Kobayashi W, Yoneda N, Matsuda S, Ikeda K, Hoshii T, Hirao A, Miyake K, Barber GN, Arita M, Ishii KJ, Akira S, Saito T.

Life Sci Alliance. 2019 Jan 25;2(1). pii: e201800282. doi: 10.26508/lsa.201800282. Print 2019 Feb.

13.

A unique nanoparticulate TLR9 agonist enables a HA split vaccine to confer FcγR-mediated protection against heterologous lethal influenza virus infection.

Yamamoto T, Masuta Y, Momota M, Kanekiyo M, Kanuma T, Takahama S, Moriishi E, Yasutomi Y, Saito T, Graham BS, Takahashi Y, Ishii KJ.

Int Immunol. 2019 Feb 15;31(2):81-90. doi: 10.1093/intimm/dxy069.

PMID:
30535055
14.

DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination.

Hayashi T, Momota M, Kuroda E, Kusakabe T, Kobari S, Makisaka K, Ohno Y, Suzuki Y, Nakagawa F, Lee MSJ, Coban C, Onodera R, Higashi T, Motoyama K, Ishii KJ, Arima H.

Front Immunol. 2018 Nov 20;9:2619. doi: 10.3389/fimmu.2018.02619. eCollection 2018.

15.

Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection.

Fujiwara S, Hoshizaki M, Ichida Y, Lex D, Kuroda E, Ishii KJ, Magi S, Okada M, Takao H, Gandou M, Imai H, Hara R, Herzog H, Yoshimura A, Okamura H, Penninger JM, Slutsky AS, Uhlig S, Kuba K, Imai Y.

Nat Microbiol. 2019 Feb;4(2):258-268. doi: 10.1038/s41564-018-0289-1. Epub 2018 Nov 19.

PMID:
30455472
16.

The protective effects of nasal PcrV-CpG oligonucleotide vaccination against Pseudomonas aeruginosa pneumonia.

Naito Y, Hamaoka S, Kinoshita M, Kainuma A, Shimizu M, Katoh H, Moriyama K, Ishii KJ, Sawa T.

Microbiol Immunol. 2018 Dec;62(12):774-785. doi: 10.1111/1348-0421.12658.

PMID:
30378708
17.

Corrigendum to "Designing an immunocyte-targeting delivery system by use of beta-glucan" [Vaccine 36 (2018) 186-189].

Miyamoto N, Mochizuki S, Kobiyama K, Ishii KJ, Sakurai K.

Vaccine. 2018 Oct 29;36(45):6892. doi: 10.1016/j.vaccine.2018.09.047. Epub 2018 Sep 29. No abstract available.

PMID:
30279089
18.

Epithelial TRAF6 drives IL-17-mediated psoriatic inflammation.

Matsumoto R, Dainichi T, Tsuchiya S, Nomura T, Kitoh A, Hayden MS, Ishii KJ, Tanaka M, Honda T, Egawa G, Otsuka A, Nakajima S, Sakurai K, Nakano Y, Kobayashi T, Sugimoto Y, Kabashima K.

JCI Insight. 2018 Aug 9;3(15). pii: 121175. doi: 10.1172/jci.insight.121175. eCollection 2018 Aug 9.

19.

Development of screening method for intranasal influenza vaccine and adjuvant safety in preclinical study.

Hiradate Y, Sasaki E, Momose H, Asanuma H, Furuhata K, Takai M, Aoshi T, Yamada H, Ishii KJ, Tanemura K, Mizukami T, Hamaguchi I.

Biologicals. 2018 Sep;55:43-52. doi: 10.1016/j.biologicals.2018.07.001. Epub 2018 Jul 14.

PMID:
30017557
20.

Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice.

Nagatake T, Suzuki H, Hirata SI, Matsumoto N, Wada Y, Morimoto S, Nasu A, Shimojou M, Kawano M, Ogami K, Tsujimura Y, Kuroda E, Iijima N, Hosomi K, Ishii KJ, Nosaka T, Yasutomi Y, Kunisawa J.

Int Immunol. 2018 Sep 25;30(10):471-481. doi: 10.1093/intimm/dxy046.

21.

Combination and inducible adjuvants targeting nucleic acid sensors.

Temizoz B, Kuroda E, Ishii KJ.

Curr Opin Pharmacol. 2018 Aug;41:104-113. doi: 10.1016/j.coph.2018.05.003. Epub 2018 Jun 2. Review.

22.

Carbonate Apatite Nanoparticles Act as Potent Vaccine Adjuvant Delivery Vehicles by Enhancing Cytokine Production Induced by Encapsulated Cytosine-Phosphate-Guanine Oligodeoxynucleotides.

Takahashi H, Misato K, Aoshi T, Yamamoto Y, Kubota Y, Wu X, Kuroda E, Ishii KJ, Yamamoto H, Yoshioka Y.

Front Immunol. 2018 Apr 18;9:783. doi: 10.3389/fimmu.2018.00783. eCollection 2018.

23.

Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner.

Katayama Y, Tachibana M, Kurisu N, Oya Y, Terasawa Y, Goda H, Kobiyama K, Ishii KJ, Akira S, Mizuguchi H, Sakurai F.

J Immunol. 2018 Apr 15;200(8):2987-2999. doi: 10.4049/jimmunol.1700435. Epub 2018 Mar 19.

24.

In vitro marker gene expression analyses in human peripheral blood mononuclear cells: A tool to assess safety of influenza vaccines in humans.

Sasaki E, Momose H, Hiradate Y, Ishii KJ, Mizukami T, Hamaguchi I.

J Immunotoxicol. 2018 Dec;15(1):53-62. doi: 10.1080/1547691X.2018.1447052.

PMID:
29521144
25.

Eosinophil depletion suppresses radiation-induced small intestinal fibrosis.

Takemura N, Kurashima Y, Mori Y, Okada K, Ogino T, Osawa H, Matsuno H, Aayam L, Kaneto S, Park EJ, Sato S, Matsunaga K, Tamura Y, Ouchi Y, Kumagai Y, Kobayashi D, Suzuki Y, Yoshioka Y, Nishimura J, Mori M, Ishii KJ, Rothenberg ME, Kiyono H, Akira S, Uematsu S.

Sci Transl Med. 2018 Feb 21;10(429). pii: eaan0333. doi: 10.1126/scitranslmed.aan0333.

PMID:
29467297
26.

An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates.

Masuta Y, Yamamoto T, Natsume-Kitatani Y, Kanuma T, Moriishi E, Kobiyama K, Mizuguchi K, Yasutomi Y, Ishii KJ.

J Immunol. 2018 Mar 15;200(6):2067-2075. doi: 10.4049/jimmunol.1701183. Epub 2018 Feb 5.

27.

Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity.

Shibata N, Kunisawa J, Hosomi K, Fujimoto Y, Mizote K, Kitayama N, Shimoyama A, Mimuro H, Sato S, Kishishita N, Ishii KJ, Fukase K, Kiyono H.

Mucosal Immunol. 2018 May;11(3):693-702. doi: 10.1038/mi.2017.103. Epub 2018 Feb 7.

PMID:
29411777
28.

Modeling for influenza vaccines and adjuvants profile for safety prediction system using gene expression profiling and statistical tools.

Sasaki E, Momose H, Hiradate Y, Furuhata K, Takai M, Asanuma H, Ishii KJ, Mizukami T, Hamaguchi I.

PLoS One. 2018 Feb 6;13(2):e0191896. doi: 10.1371/journal.pone.0191896. eCollection 2018.

29.

Tissue-specific immunopathology during malaria infection.

Coban C, Lee MSJ, Ishii KJ.

Nat Rev Immunol. 2018 Apr;18(4):266-278. doi: 10.1038/nri.2017.138. Epub 2018 Jan 15. Review.

PMID:
29332936
30.

Designing an immunocyte-targeting delivery system by use of beta-glucan.

Miyamoto N, Mochizuki S, Kobiyama K, Ishii KJ, Sakurai K.

Vaccine. 2018 Jan 2;36(1):186-189. doi: 10.1016/j.vaccine.2017.11.053. Epub 2017 Nov 22. Erratum in: Vaccine. 2018 Oct 29;36(45):6892.

PMID:
29174675
31.

T Helper 17 Promotes Induction of Antigen-Specific Gut-Mucosal Cytotoxic T Lymphocytes following Adenovirus Vector Vaccination.

Hemmi M, Tachibana M, Fujimoto N, Shoji M, Sakurai F, Kobiyama K, Ishii KJ, Akira S, Mizuguchi H.

Front Immunol. 2017 Nov 6;8:1456. doi: 10.3389/fimmu.2017.01456. eCollection 2017.

32.

Essential Role of CARD14 in Murine Experimental Psoriasis.

Tanaka M, Kobiyama K, Honda T, Uchio-Yamada K, Natsume-Kitatani Y, Mizuguchi K, Kabashima K, Ishii KJ.

J Immunol. 2018 Jan 1;200(1):71-81. doi: 10.4049/jimmunol.1700995. Epub 2017 Nov 17.

33.

Evaluation of marker gene expression as a potential predictive marker of leukopenic toxicity for inactivated influenza vaccines.

Sasaki E, Momose H, Hiradate Y, Furuhata K, Takai M, Kamachi K, Asanuma H, Ishii KJ, Mizukami T, Hamaguchi I.

Biologicals. 2017 Nov;50:100-108. doi: 10.1016/j.biologicals.2017.08.003. Epub 2017 Aug 31.

PMID:
28838806
34.

Plasmodium products persist in the bone marrow and promote chronic bone loss.

Lee MSJ, Maruyama K, Fujita Y, Konishi A, Lelliott PM, Itagaki S, Horii T, Lin JW, Khan SM, Kuroda E, Akira S, Ishii KJ, Coban C.

Sci Immunol. 2017 Jun 2;2(12). pii: eaam8093. doi: 10.1126/sciimmunol.aam8093.

PMID:
28783657
35.

Isoflurane is a suitable alternative to ether for anesthetizing rats prior to euthanasia for gene expression analysis.

Nakatsu N, Igarashi Y, Aoshi T, Hamaguchi I, Saito M, Mizukami T, Momose H, Ishii KJ, Yamada H.

J Toxicol Sci. 2017;42(4):491-497. doi: 10.2131/jts.42.491.

36.

Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo.

Uchiyama R, Yonehara S, Taniguchi S, Ishido S, Ishii KJ, Tsutsui H.

J Immunol. 2017 Aug 1;199(3):1122-1130. doi: 10.4049/jimmunol.1601373. Epub 2017 Jul 3.

37.

CD63-Mediated Antigen Delivery into Extracellular Vesicles via DNA Vaccination Results in Robust CD8+ T Cell Responses.

Kanuma T, Yamamoto T, Kobiyama K, Moriishi E, Masuta Y, Kusakabe T, Ozasa K, Kuroda E, Jounai N, Ishii KJ.

J Immunol. 2017 Jun 15;198(12):4707-4715. doi: 10.4049/jimmunol.1600731. Epub 2017 May 15.

38.

Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific.

Nishijima N, Hirai T, Misato K, Aoyama M, Kuroda E, Ishii KJ, Higashisaka K, Yoshioka Y, Tsutsumi Y.

Front Immunol. 2017 Apr 3;8:379. doi: 10.3389/fimmu.2017.00379. eCollection 2017.

39.

Efficacy comparison of adjuvants in PcrV vaccine against Pseudomonas aeruginosa pneumonia.

Hamaoka S, Naito Y, Katoh H, Shimizu M, Kinoshita M, Akiyama K, Kainuma A, Moriyama K, Ishii KJ, Sawa T.

Microbiol Immunol. 2017 Feb;61(2):64-74. doi: 10.1111/1348-0421.12467.

40.

Allergic Responses Induced by the Immunomodulatory Effects of Nanomaterials upon Skin Exposure.

Yoshioka Y, Kuroda E, Hirai T, Tsutsumi Y, Ishii KJ.

Front Immunol. 2017 Feb 16;8:169. doi: 10.3389/fimmu.2017.00169. eCollection 2017. Review.

41.

Mapping circulating serum miRNAs to their immune-related target mRNAs.

Nosirov B, Billaud J, Vandenbon A, Diez D, Wijaya E, Ishii KJ, Teraguchi S, Standley DM.

Adv Appl Bioinform Chem. 2017 Feb 2;10:1-9. doi: 10.2147/AABC.S121598. eCollection 2017.

42.

Particulates Induce Type-2 Immune Responses.

Kuroda E, Ishii KJ.

Nihon Eiseigaku Zasshi. 2017;72(1):27-31. doi: 10.1265/jjh.72.27. Review. Japanese.

43.

Development and application of adjuvant immunotherapy for cancer.

Kitahata Y, Ishii KJ.

Nihon Rinsho. 2017 Feb;75(2):329-333. Japanese.

PMID:
30562873
44.

Age-Specific Profiles of Antibody Responses against Respiratory Syncytial Virus Infection.

Jounai N, Yoshioka M, Tozuka M, Inoue K, Oka T, Miyaji K, Ishida K, Kawai N, Ikematsu H, Kawakami C, Shimizu H, Mori M, Ishii KJ, Takeshita F.

EBioMedicine. 2017 Feb;16:124-135. doi: 10.1016/j.ebiom.2017.01.014. Epub 2017 Jan 16.

45.

DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity.

Kitai Y, Kawasaki T, Sueyoshi T, Kobiyama K, Ishii KJ, Zou J, Akira S, Matsuda T, Kawai T.

J Immunol. 2017 Feb 15;198(4):1649-1659. doi: 10.4049/jimmunol.1601694. Epub 2017 Jan 9.

46.

A novel vaccinological evaluation of intranasal vaccine and adjuvant safety for preclinical tests.

Sasaki E, Kuramitsu M, Momose H, Kobiyama K, Aoshi T, Yamada H, Ishii KJ, Mizukami T, Hamaguchi I.

Vaccine. 2017 Feb 1;35(5):821-830. doi: 10.1016/j.vaccine.2016.12.036. Epub 2017 Jan 4.

PMID:
28063707
47.

Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.

Kuroda E, Ozasa K, Temizoz B, Ohata K, Koo CX, Kanuma T, Kusakabe T, Kobari S, Horie M, Morimoto Y, Nakajima S, Kabashima K, Ziegler SF, Iwakura Y, Ise W, Kurosaki T, Nagatake T, Kunisawa J, Takemura N, Uematsu S, Hayashi M, Aoshi T, Kobiyama K, Coban C, Ishii KJ.

Immunity. 2016 Dec 20;45(6):1299-1310. doi: 10.1016/j.immuni.2016.11.010.

48.

Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines.

Hayashi M, Aoshi T, Haseda Y, Kobiyama K, Wijaya E, Nakatsu N, Igarashi Y, Standley DM, Yamada H, Honda-Okubo Y, Hara H, Saito T, Takai T, Coban C, Petrovsky N, Ishii KJ.

EBioMedicine. 2017 Feb;15:127-136. doi: 10.1016/j.ebiom.2016.11.015. Epub 2016 Dec 1.

49.

Induction of humoral and cellular immune response to hepatitis B virus (HBV) vaccine can be upregulated by CpG oligonucleotides complexed with Dectin-1 ligand.

Ito H, Ando T, Nakamura M, Ishida H, Kanbe A, Kobiyama K, Yamamoto T, Ishii KJ, Hara A, Seishima M, Ishikawa T.

J Viral Hepat. 2017 Feb;24(2):155-162. doi: 10.1111/jvh.12629. Epub 2016 Nov 3.

PMID:
27807909
50.

Induction of humoural and cellular immunity by immunisation with HCV particle vaccine in a non-human primate model.

Yokokawa H, Higashino A, Suzuki S, Moriyama M, Nakamura N, Suzuki T, Suzuki R, Ishii K, Kobiyama K, Ishii KJ, Wakita T, Akari H, Kato T.

Gut. 2018 Feb;67(2):372-379. doi: 10.1136/gutjnl-2016-312208. Epub 2016 Oct 26.

PMID:
27797937

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