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Items: 1 to 50 of 69

1.

FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress.

Okamoto Y, Abe M, Itaya A, Tomida J, Ishiai M, Takaori-Kondo A, Taoka M, Isobe T, Takata M.

FEBS J. 2019 Jan;286(1):139-150. doi: 10.1111/febs.14700. Epub 2018 Nov 27.

PMID:
30431240
2.

Replication stress induces accumulation of FANCD2 at central region of large fragile genes.

Okamoto Y, Iwasaki WM, Kugou K, Takahashi KK, Oda A, Sato K, Kobayashi W, Kawai H, Sakasai R, Takaori-Kondo A, Yamamoto T, Kanemaki MT, Taoka M, Isobe T, Kurumizaka H, Innan H, Ohta K, Ishiai M, Takata M.

Nucleic Acids Res. 2018 Apr 6;46(6):2932-2944. doi: 10.1093/nar/gky058.

3.

Candida albicans fatty acyl-CoA synthetase, CaFaa4p, is involved in the uptake of exogenous long-chain fatty acids and cell activity in the biofilm.

Tejima K, Ishiai M, Murayama SO, Iwatani S, Kajiwara S.

Curr Genet. 2018 Apr;64(2):429-441. doi: 10.1007/s00294-017-0751-2. Epub 2017 Sep 23.

PMID:
28942495
4.

Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells.

Kadoda K, Moriwaki T, Tsuda M, Sasanuma H, Ishiai M, Takata M, Ide H, Masunaga SI, Takeda S, Tano K.

PLoS One. 2017 Sep 19;12(9):e0185141. doi: 10.1371/journal.pone.0185141. eCollection 2017.

5.

PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.

Mochizuki AL, Katanaya A, Hayashi E, Hosokawa M, Moribe E, Motegi A, Ishiai M, Takata M, Kondoh G, Watanabe H, Nakatsuji N, Chuma S.

Mol Cell Biol. 2017 Nov 13;37(23). pii: e00117-17. doi: 10.1128/MCB.00117-17. Print 2017 Dec 1.

6.

Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia.

Knies K, Inano S, Ramírez MJ, Ishiai M, Surrallés J, Takata M, Schindler D.

J Clin Invest. 2017 Aug 1;127(8):3013-3027. doi: 10.1172/JCI92069. Epub 2017 Jul 10.

7.

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.

Inano S, Sato K, Katsuki Y, Kobayashi W, Tanaka H, Nakajima K, Nakada S, Miyoshi H, Knies K, Takaori-Kondo A, Schindler D, Ishiai M, Kurumizaka H, Takata M.

Mol Cell. 2017 Jun 1;66(5):622-634.e8. doi: 10.1016/j.molcel.2017.04.022.

8.

Activation of the FA pathway mediated by phosphorylation and ubiquitination.

Ishiai M, Sato K, Tomida J, Kitao H, Kurumizaka H, Takata M.

Mutat Res. 2017 Oct;803-805:89-95. doi: 10.1016/j.mrfmmm.2017.05.003. Epub 2017 May 5. Review.

PMID:
28552166
9.

Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks.

Ling C, Huang J, Yan Z, Li Y, Ohzeki M, Ishiai M, Xu D, Takata M, Seidman M, Wang W.

Cell Discov. 2016 Dec 20;2:16047. doi: 10.1038/celldisc.2016.47. eCollection 2016.

10.

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.

Sato K, Shimomuki M, Katsuki Y, Takahashi D, Kobayashi W, Ishiai M, Miyoshi H, Takata M, Kurumizaka H.

Nucleic Acids Res. 2016 Dec 15;44(22):10758-10771. Epub 2016 Sep 30.

11.

Defective FANCI binding by a fanconi anemia-related FANCD2 mutant.

Sato K, Ishiai M, Takata M, Kurumizaka H.

PLoS One. 2014 Dec 9;9(12):e114752. doi: 10.1371/journal.pone.0114752. eCollection 2014.

12.

The Trp53-Trp53inp1-Tnfrsf10b pathway regulates the radiation response of mouse spermatogonial stem cells.

Ishii K, Ishiai M, Morimoto H, Kanatsu-Shinohara M, Niwa O, Takata M, Shinohara T.

Stem Cell Reports. 2014 Oct 14;3(4):676-89. doi: 10.1016/j.stemcr.2014.08.006. Epub 2014 Sep 18.

13.

Forced expression of FLO11 confers pellicle-forming ability and furfural tolerance on Saccharomyces cerevisiae in ethanol production.

Nakagawa Y, Hasebe T, Ishiai M, Yamamura H, Iimura Y, Hayakawa M.

Biosci Biotechnol Biochem. 2014;78(4):714-7. doi: 10.1080/09168451.2014.895660. Epub 2014 May 9.

PMID:
25036972
14.

FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair.

Unno J, Itaya A, Taoka M, Sato K, Tomida J, Sakai W, Sugasawa K, Ishiai M, Ikura T, Isobe T, Kurumizaka H, Takata M.

Cell Rep. 2014 May 22;7(4):1039-47. doi: 10.1016/j.celrep.2014.04.005. Epub 2014 May 1.

15.

Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents.

Hosono Y, Abe T, Ishiai M, Islam MN, Arakawa H, Wang W, Takeda S, Ishii Y, Takata M, Seki M, Enomoto T.

Biochim Biophys Acta. 2014 May;1843(5):1002-12. doi: 10.1016/j.bbamcr.2014.01.005. Epub 2014 Jan 10.

16.

A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.

Tomida J, Itaya A, Shigechi T, Unno J, Uchida E, Ikura M, Masuda Y, Matsuda S, Adachi J, Kobayashi M, Meetei AR, Maehara Y, Yamamoto K, Kamiya K, Matsuura A, Matsuda T, Ikura T, Ishiai M, Takata M.

Nucleic Acids Res. 2013 Aug;41(14):6930-41. doi: 10.1093/nar/gkt467. Epub 2013 May 30.

17.

Effects of L-arginine on anatomical and electrophysiological deterioration of the eye in a rodent model of nonarteritic ischemic optic neuropathy.

Chuman H, Maekubo T, Osako T, Ishiai M, Kawano N, Nao-I N.

Jpn J Ophthalmol. 2013 Jul;57(4):402-9. doi: 10.1007/s10384-013-0250-z. Epub 2013 May 29.

PMID:
23712653
18.

Effects of steroid administration and transcorneal electrical stimulation on the anatomic and electrophysiologic deterioration of nonarteritic ischemic optic neuropathy in a rodent model.

Osako T, Chuman H, Maekubo T, Ishiai M, Kawano N, Nao-I N.

Jpn J Ophthalmol. 2013 Jul;57(4):410-5. doi: 10.1007/s10384-012-0203-y. Epub 2013 May 9.

PMID:
23657677
19.

Establishment of the DNA repair-defective mutants in DT40 cells.

Ishiai M, Uchida E, Takata M.

Methods Mol Biol. 2012;920:39-49. doi: 10.1007/978-1-61779-998-3_4.

PMID:
22941595
20.

Rodent model of nonarteritic ischemic optic neuropathy and its electrophysiological evaluation.

Chuman H, Maekubo T, Osako T, Kodama Y, Ishiai M, Nao-I N.

Jpn J Ophthalmol. 2012 Sep;56(5):518-27. doi: 10.1007/s10384-012-0167-y. Epub 2012 Aug 3.

PMID:
22864772
21.

Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair.

Sato K, Ishiai M, Toda K, Furukoshi S, Osakabe A, Tachiwana H, Takizawa Y, Kagawa W, Kitao H, Dohmae N, Obuse C, Kimura H, Takata M, Kurumizaka H.

EMBO J. 2012 Aug 29;31(17):3524-36. doi: 10.1038/emboj.2012.197. Epub 2012 Jul 24.

22.

Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks.

Nishimura K, Ishiai M, Horikawa K, Fukagawa T, Takata M, Takisawa H, Kanemaki MT.

Mol Cell. 2012 Aug 24;47(4):511-22. doi: 10.1016/j.molcel.2012.05.047. Epub 2012 Jul 5.

23.

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI.

Sato K, Toda K, Ishiai M, Takata M, Kurumizaka H.

Nucleic Acids Res. 2012 May;40(10):4553-61. doi: 10.1093/nar/gks053. Epub 2012 Jan 28.

24.

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway.

Shigechi T, Tomida J, Sato K, Kobayashi M, Eykelenboom JK, Pessina F, Zhang Y, Uchida E, Ishiai M, Lowndes NF, Yamamoto K, Kurumizaka H, Maehara Y, Takata M.

Cancer Res. 2012 Mar 1;72(5):1149-56. doi: 10.1158/0008-5472.CAN-11-2904. Epub 2012 Jan 18.

25.

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5.

Bell DW, Sikdar N, Lee KY, Price JC, Chatterjee R, Park HD, Fox J, Ishiai M, Rudd ML, Pollock LM, Fogoros SK, Mohamed H, Hanigan CL; NISC Comparative Sequencing Program, Zhang S, Cruz P, Renaud G, Hansen NF, Cherukuri PF, Borate B, McManus KJ, Stoepel J, Sipahimalani P, Godwin AK, Sgroi DC, Merino MJ, Elliot G, Elkahloun A, Vinson C, Takata M, Mullikin JC, Wolfsberg TG, Hieter P, Lim DS, Myung K.

PLoS Genet. 2011 Aug;7(8):e1002245. doi: 10.1371/journal.pgen.1002245. Epub 2011 Aug 25.

26.

CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway.

Kometani K, Yamada T, Sasaki Y, Yokosuka T, Saito T, Rajewsky K, Ishiai M, Hikida M, Kurosaki T.

J Exp Med. 2011 Jul 4;208(7):1447-57. doi: 10.1084/jem.20102665. Epub 2011 Jun 27.

27.

The role of SNM1 family nucleases in etoposide-induced apoptosis.

Hosono Y, Abe T, Ishiai M, Takata M, Enomoto T, Seki M.

Biochem Biophys Res Commun. 2011 Jul 8;410(3):568-73. doi: 10.1016/j.bbrc.2011.06.027. Epub 2011 Jun 12.

PMID:
21683065
28.

[DNA interstrand crosslink repair in vertebrate cells].

Ishiai M.

Seikagaku. 2009 Nov;81(11):998-1004. Review. Japanese. No abstract available.

PMID:
19999583
29.

The Fanconi anemia pathway: insights from somatic cell genetics using DT40 cell line.

Takata M, Ishiai M, Kitao H.

Mutat Res. 2009 Jul 31;668(1-2):92-102. doi: 10.1016/j.mrfmmm.2008.12.012. Epub 2009 Jan 17. Review.

PMID:
19622405
30.

[Fanconi anemia and DNA-damage response network].

Matsushita N, Kitao H, Ishiai M, Takata M.

Tanpakushitsu Kakusan Koso. 2009 Mar;54(4 Suppl):580-5. Review. Japanese. No abstract available.

PMID:
21089513
31.

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita-Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M.

Nat Struct Mol Biol. 2008 Nov;15(11):1138-46. doi: 10.1038/nsmb.1504. Epub 2008 Oct 19.

32.

KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation.

Abe T, Ishiai M, Hosono Y, Yoshimura A, Tada S, Adachi N, Koyama H, Takata M, Takeda S, Enomoto T, Seki M.

Cell Signal. 2008 Nov;20(11):1978-85. doi: 10.1016/j.cellsig.2008.07.006. Epub 2008 Jul 10.

PMID:
18674614
33.

Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line.

Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M.

Cancer Res. 2007 Aug 15;67(16):7807-14.

34.

Fanconi anemia: genetic analysis of a human disease using chicken system.

Takata M, Kitao H, Ishiai M.

Cytogenet Genome Res. 2007;117(1-4):346-51.

PMID:
17675877
35.

The Fanconi anemia pathway promotes homologous recombination repair in DT40 cell line.

Takata M, Yamamoto K, Matsushita N, Kitao H, Hirano S, Ishiai M.

Subcell Biochem. 2006;40:295-311. Review.

PMID:
17623912
36.

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway.

Ling C, Ishiai M, Ali AM, Medhurst AL, Neveling K, Kalb R, Yan Z, Xue Y, Oostra AB, Auerbach AD, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Takata M, Meetei AR, Wang W.

EMBO J. 2007 Apr 18;26(8):2104-14. Epub 2007 Mar 29.

37.

A requirement of FancL and FancD2 monoubiquitination in DNA repair.

Seki S, Ohzeki M, Uchida A, Hirano S, Matsushita N, Kitao H, Oda T, Yamashita T, Kashihara N, Tsubahara A, Takata M, Ishiai M.

Genes Cells. 2007 Mar;12(3):299-310.

38.

53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis.

Iwabuchi K, Hashimoto M, Matsui T, Kurihara T, Shimizu H, Adachi N, Ishiai M, Yamamoto K, Tauchi H, Takata M, Koyama H, Date T.

Genes Cells. 2006 Aug;11(8):935-48.

39.

Functional interplay between BRCA2/FancD1 and FancC in DNA repair.

Kitao H, Yamamoto K, Matsushita N, Ohzeki M, Ishiai M, Takata M.

J Biol Chem. 2006 Jul 28;281(30):21312-20. Epub 2006 May 10.

40.

Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.

Nojima K, Hochegger H, Saberi A, Fukushima T, Kikuchi K, Yoshimura M, Orelli BJ, Bishop DK, Hirano S, Ohzeki M, Ishiai M, Yamamoto K, Takata M, Arakawa H, Buerstedde JM, Yamazoe M, Kawamoto T, Araki K, Takahashi JA, Hashimoto N, Takeda S, Sonoda E.

Cancer Res. 2005 Dec 15;65(24):11704-11.

41.

A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair.

Matsushita N, Kitao H, Ishiai M, Nagashima N, Hirano S, Okawa K, Ohta T, Yu DS, McHugh PJ, Hickson ID, Venkitaraman AR, Kurumizaka H, Takata M.

Mol Cell. 2005 Sep 16;19(6):841-7.

42.

Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells.

Matsushita N, Takami Y, Kimura M, Tachiiri S, Ishiai M, Nakayama T, Takata M.

Genes Cells. 2005 Apr;10(4):321-32.

43.

Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.

Hirano S, Yamamoto K, Ishiai M, Yamazoe M, Seki M, Matsushita N, Ohzeki M, Yamashita YM, Arakawa H, Buerstedde JM, Enomoto T, Takeda S, Thompson LH, Takata M.

EMBO J. 2005 Jan 26;24(2):418-27. Epub 2004 Dec 23.

44.

Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.

Yamamoto K, Hirano S, Ishiai M, Morishima K, Kitao H, Namikoshi K, Kimura M, Matsushita N, Arakawa H, Buerstedde JM, Komatsu K, Thompson LH, Takata M.

Mol Cell Biol. 2005 Jan;25(1):34-43.

45.

DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.

Ishiai M, Kimura M, Namikoshi K, Yamazoe M, Yamamoto K, Arakawa H, Agematsu K, Matsushita N, Takeda S, Buerstedde JM, Takata M.

Mol Cell Biol. 2004 Dec;24(24):10733-41.

46.

Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells.

Yamamoto K, Ishiai M, Matsushita N, Arakawa H, Lamerdin JE, Buerstedde JM, Tanimoto M, Harada M, Thompson LH, Takata M.

Mol Cell Biol. 2003 Aug;23(15):5421-30.

47.

BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins.

Chiu CW, Dalton M, Ishiai M, Kurosaki T, Chan AC.

EMBO J. 2002 Dec 2;21(23):6461-72.

48.

Developmental differences in B cell receptor-induced signal transduction.

Kövesdi D, Koncz G, Iványi-Nagy R, Caspi Y, Ishiai M, Kurosaki T, Gergely J, Haimovich J, Sármay G.

Cell Signal. 2002 Jun;14(6):563-72.

PMID:
11897497
49.

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation.

Inabe K, Ishiai M, Scharenberg AM, Freshney N, Downward J, Kurosaki T.

J Exp Med. 2002 Jan 21;195(2):189-200.

50.

Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling.

Watanabe D, Hashimoto S, Ishiai M, Matsushita M, Baba Y, Kishimoto T, Kurosaki T, Tsukada S.

J Biol Chem. 2001 Oct 19;276(42):38595-601. Epub 2001 Aug 15.

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