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Items: 33


Effects of a Novel Probiotic Combination on Pathogenic Bacterial-Fungal Polymicrobial Biofilms.

Hager CL, Isham N, Schrom KP, Chandra J, McCormick T, Miyagi M, Ghannoum MA.

MBio. 2019 Apr 2;10(2). pii: e00338-19. doi: 10.1128/mBio.00338-19.


A Novel 1,3-Beta-d-Glucan Inhibitor, Ibrexafungerp (Formerly SCY-078), Shows Potent Activity in the Lower pH Environment of Vulvovaginitis.

Larkin EL, Long L, Isham N, Borroto-Esoda K, Barat S, Angulo D, Wring S, Ghannoum M.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02611-18. doi: 10.1128/AAC.02611-18. Print 2019 May.


The Gut Microbiome as a Major Regulator of the Gut-Skin Axis.

Salem I, Ramser A, Isham N, Ghannoum MA.

Front Microbiol. 2018 Jul 10;9:1459. doi: 10.3389/fmicb.2018.01459. eCollection 2018. Review.


In Vitro and In Vivo Activity of a Novel Catheter Lock Solution against Bacterial and Fungal Biofilms.

Chandra J, Long L, Isham N, Mukherjee PK, DiSciullo G, Appelt K, Ghannoum MA.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00722-18. doi: 10.1128/AAC.00722-18. Print 2018 Aug.


Evaluation of the Antifungal Activity of the Novel Oral Glucan Synthase Inhibitor SCY-078, Singly and in Combination, for the Treatment of Invasive Aspergillosis.

Ghannoum M, Long L, Larkin EL, Isham N, Sherif R, Borroto-Esoda K, Barat S, Angulo D.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00244-18. doi: 10.1128/AAC.00244-18. Print 2018 Jun.


Examining the importance of laboratory and diagnostic testing when treating and diagnosing onychomycosis.

Ghannoum M, Mukherjee P, Isham N, Markinson B, Rosso JD, Leal L.

Int J Dermatol. 2018 Feb;57(2):131-138. doi: 10.1111/ijd.13690. Epub 2017 Jun 27. Review.


The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation.

Larkin E, Hager C, Chandra J, Mukherjee PK, Retuerto M, Salem I, Long L, Isham N, Kovanda L, Borroto-Esoda K, Wring S, Angulo D, Ghannoum M.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02396-16. doi: 10.1128/AAC.02396-16. Print 2017 May.


In vitro antifungal activity of ME1111, a new topical agent for onychomycosis, against clinical isolates of dermatophytes.

Ghannoum M, Isham N, Long L.

Antimicrob Agents Chemother. 2015 Sep;59(9):5154-8. doi: 10.1128/AAC.00992-15. Epub 2015 Jun 8.


Ability of hydroxypropyl chitosan nail lacquer to protect against dermatophyte nail infection.

Ghannoum MA, Long L, Isham N, Bulgheroni A, Setaro M, Caserini M, Palmieri R, Mailland F.

Antimicrob Agents Chemother. 2015 Apr;59(4):1844-8. doi: 10.1128/AAC.04842-14. Epub 2014 Dec 29.


Multilaboratory testing of antifungal drug combinations against Candida species and Aspergillus fumigatus: utility of 100 percent inhibition as the endpoint.

Ren P, Luo M, Lin S, Ghannoum MA, Isham N, Diekema DJ, Pfaller MA, Messer S, Lockhart SR, Iqbal N, Chaturvedi V.

Antimicrob Agents Chemother. 2015 Mar;59(3):1759-66. doi: 10.1128/AAC.04545-14. Epub 2014 Dec 15.


Role of oral candidiasis in TB and HIV co-infection: AIDS Clinical Trial Group Protocol A5253.

Shiboski CH, Chen H, Ghannoum MA, Komarow L, Evans S, Mukherjee PK, Isham N, Katzenstein D, Asmelash A, Omozoarhe AE, Gengiah S, Allen R, Tripathy S, Swindells S; AIDS Clinical Trials Group Network and Oral HIV/AIDS Research Alliance.

Int J Tuberc Lung Dis. 2014 Jun;18(6):682-8. doi: 10.5588/ijtld.13.0729.


Fungal nail infections (onychomycosis): a never-ending story?

Ghannoum M, Isham N.

PLoS Pathog. 2014 Jun 5;10(6):e1004105. doi: 10.1371/journal.ppat.1004105. eCollection 2014 Jun. No abstract available.


A second look at efficacy criteria for onychomycosis: clinical and mycological cure.

Ghannoum M, Isham N, Catalano V.

Br J Dermatol. 2014 Jan;170(1):182-7. doi: 10.1111/bjd.12594. Review.


In vitro antifungal activity of naftifine hydrochloride against dermatophytes.

Ghannoum M, Isham N, Verma A, Plaum S, Fleischer A Jr, Hardas B.

Antimicrob Agents Chemother. 2013 Sep;57(9):4369-72. doi: 10.1128/AAC.01084-13. Epub 2013 Jul 1.


PHOTO QUIZ. An unusual periorbital rash in a child.

Weaver G, Newmyer R, Yeo KT, Jacobs MR, Tamburro J, Isham NC, Ghannoum M, Gonzalez BE.

Clin Infect Dis. 2012 Sep;55(6):844, 885-6. doi: 10.1093/cid/cis498. No abstract available.


Optimization of an infected shoe model for the evaluation of an ultraviolet shoe sanitizer device.

Ghannoum MA, Isham N, Long L.

J Am Podiatr Med Assoc. 2012 Jul-Aug;102(4):309-13.


Nonspecific effect of Mycograb on amphotericin B MIC.

Richie DL, Ghannoum MA, Isham N, Thompson KV, Ryder NS.

Antimicrob Agents Chemother. 2012 Jul;56(7):3963-4. doi: 10.1128/AAC.00435-12. Epub 2012 Apr 16.


Evaluation of the morphological effects of TDT 067 (terbinafine in Transfersome) and conventional terbinafine on dermatophyte hyphae in vitro and in vivo.

Ghannoum M, Isham N, Henry W, Kroon HA, Yurdakul S.

Antimicrob Agents Chemother. 2012 May;56(5):2530-4. doi: 10.1128/AAC.05998-11. Epub 2012 Feb 21.


Antimicrobial activity of B-Lock against bacterial and Candida spp. causing catheter-related bloodstream infections.

Ghannoum MA, Isham N, Jacobs MR.

Antimicrob Agents Chemother. 2011 Sep;55(9):4430-1. doi: 10.1128/AAC.00677-11. Epub 2011 Jul 5.


Activity of TDT 067 (terbinafine in Transfersome) against agents of onychomycosis, as determined by minimum inhibitory and fungicidal concentrations.

Ghannoum M, Isham N, Herbert J, Henry W, Yurdakul S.

J Clin Microbiol. 2011 May;49(5):1716-20. doi: 10.1128/JCM.00083-11. Epub 2011 Mar 16.


Repeated exposure of Candida spp. to miconazole demonstrates no development of resistance.

Ghannoum MA, Herbert J, Isham N.

Mycoses. 2011 Jul;54(4):e175-7. doi: 10.1111/j.1439-0507.2010.01867.x. Epub 2010 Mar 4.


Antifungal activity of miconazole against recent Candida strains.

Isham N, Ghannoum MA.

Mycoses. 2010 Sep;53(5):434-7. doi: 10.1111/j.1439-0507.2009.01728.x. Epub 2009 Jun 15.


Comparison of the in vitro activity of terbinafine and lanoconazole against dermatophytes.

Ghannoum MA, Welshenbaugh A, Imamura Y, Isham N, Mallefet P, Yamaguchi H.

Mycoses. 2010 Jul;53(4):311-3. doi: 10.1111/j.1439-0507.2009.01723.x. Epub 2009 May 5.


Susceptibility of dermatophyte isolates obtained from a large worldwide terbinafine tinea capitis clinical trial.

Ghannoum MA, Wraith LA, Cai B, Nyirady J, Isham N.

Br J Dermatol. 2008 Sep;159(3):711-3. doi: 10.1111/j.1365-2133.2008.08648.x. Epub 2008 May 28.


Determination of MICs of aminocandin for Candida spp. and filamentous fungi.

Isham N, Ghannoum MA.

J Clin Microbiol. 2006 Dec;44(12):4342-4. Epub 2006 Oct 4.


Tinea capitis in Cleveland: survey of elementary school students.

Ghannoum M, Isham N, Hajjeh R, Cano M, Al-Hasawi F, Yearick D, Warner J, Long L, Jessup C, Elewski B.

J Am Acad Dermatol. 2003 Feb;48(2):189-93.


Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine.

Mukherjee PK, Leidich SD, Isham N, Leitner I, Ryder NS, Ghannoum MA.

Antimicrob Agents Chemother. 2003 Jan;47(1):82-6.


A large-scale North American study of fungal isolates from nails: the frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns.

Ghannoum MA, Hajjeh RA, Scher R, Konnikov N, Gupta AK, Summerbell R, Sullivan S, Daniel R, Krusinski P, Fleckman P, Rich P, Odom R, Aly R, Pariser D, Zaiac M, Rebell G, Lesher J, Gerlach B, Ponce-De-Leon GF, Ghannoum A, Warner J, Isham N, Elewski B.

J Am Acad Dermatol. 2000 Oct;43(4):641-8.


Antifungal susceptibilities and genetic relatedness of serial Trichophyton rubrum isolates from patients with onychomycosis of the toenail.

Bradley MC, Leidich S, Isham N, Elewski BE, Ghannoum MA.

Mycoses. 1999;42 Suppl 2:105-10.


Antifungal susceptibilities and genetic relatedness of serial Trichophyton rubrum isolates from patients with onychomycosis of the toenail.

Bradley MC, Leidich S, Isham N, Elewski BE, Ghannoum MA.

Mycoses. 1999 Dec;42 Suppl 2:105-110. doi: 10.1111/j.1439-0507.1999.tb00024.x.


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