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Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho.

Bzymek R, Horsthemke M, Isfort K, Mohr S, Tjaden K, Müller-Tidow C, Thomann M, Schwerdtle T, Bähler M, Schwab A, Hanley PJ.

Sci Rep. 2016 Apr 28;6:25016. doi: 10.1038/srep25016.


Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to complement C5a is phosphatidylinositol 3-kinase (PI3K)- and p38 mitogen-activated protein kinase (MAPK)-independent.

Isfort K, Ebert F, Bornhorst J, Sargin S, Kardakaris R, Pasparakis M, Bähler M, Schwerdtle T, Schwab A, Hanley PJ.

J Biol Chem. 2011 Dec 30;286(52):44776-87. doi: 10.1074/jbc.M111.289793. Epub 2011 Nov 4.


Autocrine purinergic receptor signaling is essential for macrophage chemotaxis.

Kronlage M, Song J, Sorokin L, Isfort K, Schwerdtle T, Leipziger J, Robaye B, Conley PB, Kim HC, Sargin S, Schön P, Schwab A, Hanley PJ.

Sci Signal. 2010 Jul 27;3(132):ra55. doi: 10.1126/scisignal.2000588.

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