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Items: 37


Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer.

Chen KY, Santos Afonso ED, Enouf V, Isel C, Naffakh N.

PLoS Pathog. 2019 Oct 3;15(10):e1008034. doi: 10.1371/journal.ppat.1008034. eCollection 2019 Oct.


Influenza NA and PB1 Gene Segments Interact during the Formation of Viral Progeny: Localization of the Binding Region within the PB1 Gene.

Gilbertson B, Zheng T, Gerber M, Printz-Schweigert A, Ong C, Marquet R, Isel C, Rockman S, Brown L.

Viruses. 2016 Aug 20;8(8). pii: E238. doi: 10.3390/v8080238.


Experimental Approaches to Study Genome Packaging of Influenza A Viruses.

Isel C, Munier S, Naffakh N.

Viruses. 2016 Aug 9;8(8). pii: E218. doi: 10.3390/v8080218. Review.


Evaluation of anti-HIV-1 mutagenic nucleoside analogues.

Vivet-Boudou V, Isel C, El Safadi Y, Smyth RP, Laumond G, Moog C, Paillart JC, Marquet R.

J Biol Chem. 2015 Jan 2;290(1):371-83. doi: 10.1074/jbc.M114.616383. Epub 2014 Nov 14.


Selective packaging of the influenza A genome and consequences for genetic reassortment.

Gerber M, Isel C, Moules V, Marquet R.

Trends Microbiol. 2014 Aug;22(8):446-55. doi: 10.1016/j.tim.2014.04.001. Epub 2014 May 2. Review.


A functional sequence-specific interaction between influenza A virus genomic RNA segments.

Gavazzi C, Yver M, Isel C, Smyth RP, Rosa-Calatrava M, Lina B, Moulès V, Marquet R.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16604-9. doi: 10.1073/pnas.1314419110. Epub 2013 Sep 25.


Critical role of segment-specific packaging signals in genetic reassortment of influenza A viruses.

Essere B, Yver M, Gavazzi C, Terrier O, Isel C, Fournier E, Giroux F, Textoris J, Julien T, Socratous C, Rosa-Calatrava M, Lina B, Marquet R, Moules V.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3840-8. doi: 10.1073/pnas.1308649110. Epub 2013 Sep 16.


An in vitro network of intermolecular interactions between viral RNA segments of an avian H5N2 influenza A virus: comparison with a human H3N2 virus.

Gavazzi C, Isel C, Fournier E, Moules V, Cavalier A, Thomas D, Lina B, Marquet R.

Nucleic Acids Res. 2013 Jan;41(2):1241-54. doi: 10.1093/nar/gks1181. Epub 2012 Dec 5.


Interaction network linking the human H3N2 influenza A virus genomic RNA segments.

Fournier E, Moules V, Essere B, Paillart JC, Sirbat JD, Cavalier A, Rolland JP, Thomas D, Lina B, Isel C, Marquet R.

Vaccine. 2012 Dec 7;30(51):7359-67. doi: 10.1016/j.vaccine.2012.09.079. Epub 2012 Oct 9.


A pyrophosphatase activity associated with purified HIV-1 particles.

Ducloux C, Mougel M, Goldschmidt V, Didierlaurent L, Marquet R, Isel C.

Biochimie. 2012 Dec;94(12):2498-507. doi: 10.1016/j.biochi.2012.06.025. Epub 2012 Jul 3.


8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription.

Vivet-Boudou V, Isel C, Sleiman M, Smyth R, Ben Gaied N, Barhoum P, Laumond G, Bec G, Götte M, Mak J, Aubertin AM, Burger A, Marquet R.

PLoS One. 2011;6(11):e27456. doi: 10.1371/journal.pone.0027456. Epub 2011 Nov 7.


A supramolecular assembly formed by influenza A virus genomic RNA segments.

Fournier E, Moules V, Essere B, Paillart JC, Sirbat JD, Isel C, Cavalier A, Rolland JP, Thomas D, Lina B, Marquet R.

Nucleic Acids Res. 2012 Mar;40(5):2197-209. doi: 10.1093/nar/gkr985. Epub 2011 Nov 10.


Initiation of HIV Reverse Transcription.

Isel C, Ehresmann C, Marquet R.

Viruses. 2010 Jan;2(1):213-43. doi: 10.3390/v2010213. Epub 2010 Jan 18.


The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA.

Keating CP, Hill MK, Hawkes DJ, Smyth RP, Isel C, Le SY, Palmenberg AC, Marshall JA, Marquet R, Nabel GJ, Mak J.

Nucleic Acids Res. 2009 Feb;37(3):945-56. doi: 10.1093/nar/gkn1015. Epub 2008 Dec 23.


Protein-induced conformational changes of RNA during the assembly of human signal recognition particle.

Menichelli E, Isel C, Oubridge C, Nagai K.

J Mol Biol. 2007 Mar 16;367(1):187-203. Epub 2006 Dec 24.


Mg2+ dependency of HIV-1 reverse transcription, inhibition by nucleoside analogues and resistance.

Goldschmidt V, Didierjean J, Ehresmann B, Ehresmann C, Isel C, Marquet R.

Nucleic Acids Res. 2006 Jan 3;34(1):42-52. Print 2006.


Nucleoside and nucleotide inhibitors of HIV-1 replication.

Vivet-Boudou V, Didierjean J, Isel C, Marquet R.

Cell Mol Life Sci. 2006 Jan;63(2):163-86. Review.


Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones.

Didierjean J, Isel C, Querré F, Mouscadet JF, Aubertin AM, Valnot JY, Piettre SR, Marquet R.

Antimicrob Agents Chemother. 2005 Dec;49(12):4884-94.


Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA.

Murchie AI, Davis B, Isel C, Afshar M, Drysdale MJ, Bower J, Potter AJ, Starkey ID, Swarbrick TM, Mirza S, Prescott CD, Vaglio P, Aboul-ela F, Karn J.

J Mol Biol. 2004 Feb 20;336(3):625-38.


Structure, function and evolution of the signal recognition particle.

Nagai K, Oubridge C, Kuglstatter A, Menichelli E, Isel C, Jovine L.

EMBO J. 2003 Jul 15;22(14):3479-85. Review.


Secondary structure of the 3' terminus of hepatitis C virus minus-strand RNA.

Schuster C, Isel C, Imbert I, Ehresmann C, Marquet R, Kieny MP.

J Virol. 2002 Aug;76(16):8058-68.


The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.

Isel C, Ehresmann C, Walter P, Ehresmann B, Marquet R.

J Biol Chem. 2001 Dec 28;276(52):48725-32. Epub 2001 Oct 19.


Dynamics of the HIV-1 reverse transcription complex during initiation of DNA synthesis.

Lanchy JM, Isel C, Keith G, Le Grice SF, Ehresmann C, Ehresmann B, Marquet R.

J Biol Chem. 2000 Apr 21;275(16):12306-12.


Structural basis for the specificity of the initiation of HIV-1 reverse transcription.

Isel C, Westhof E, Massire C, Le Grice SF, Ehresmann B, Ehresmann C, Marquet R.

EMBO J. 1999 Feb 15;18(4):1038-48.


Mutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.

Isel C, Keith G, Ehresmann B, Ehresmann C, Marquet R.

Nucleic Acids Res. 1998 Mar 1;26(5):1198-204.


Two step synthesis of (-) strong-stop DNA by avian and murine reverse transcriptases in vitro.

Isel C, Ehresmann C, Keith G, Ehresmann B, Marquet R.

Nucleic Acids Res. 1997 Feb 1;25(3):545-52.


Probing the higher order structure of RNA with peroxonitrous acid.

Götte M, Marquet R, Isel C, Anderson VE, Keith G, Gross HJ, Ehresmann C, Ehresmann B, Heumann H.

FEBS Lett. 1996 Jul 22;390(2):226-8.


Psoralen crosslinking between human immunodeficiency virus type 1 RNA and primer tRNA3(Lys).

Skripkin E, Isel C, Marquet R, Ehresmann B, Ehresmann C.

Nucleic Acids Res. 1996 Feb 1;24(3):509-14.


Structural and functional evidence that initiation and elongation of HIV-1 reverse transcription are distinct processes.

Lanchy JM, Isel C, Ehresmann C, Marquet R, Ehresmann B.

Biochimie. 1996;78(11-12):1087-96. Review.


Initiation of reverse transcription of HIV-1: secondary structure of the HIV-1 RNA/tRNA(3Lys) (template/primer).

Isel C, Ehresmann C, Keith G, Ehresmann B, Marquet R.

J Mol Biol. 1995 Mar 24;247(2):236-50.


tRNAs as primer of reverse transcriptases.

Marquet R, Isel C, Ehresmann C, Ehresmann B.

Biochimie. 1995;77(1-2):113-24. Review.


Functional sites in the 5' region of human immunodeficiency virus type 1 RNA form defined structural domains.

Baudin F, Marquet R, Isel C, Darlix JL, Ehresmann B, Ehresmann C.

J Mol Biol. 1993 Jan 20;229(2):382-97.


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