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Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds.

Solé M, Ablondi M, Binzer-Panchal A, Velie BD, Hollfelder N, Buys N, Ducro BJ, François L, Janssens S, Schurink A, Viklund Å, Eriksson S, Isaksson A, Kultima H, Mikko S, Lindgren G.

BMC Genomics. 2019 Oct 22;20(1):759. doi: 10.1186/s12864-019-6141-z.


Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases.

Enblad M, Graf W, Terman A, Pucholt P, Viklund B, Isaksson A, Birgisson H.

Ann Surg Oncol. 2019 Oct 16. doi: 10.1245/s10434-019-07923-6. [Epub ahead of print]


Inter Individual Variation and Factors Regulating the Formation of Phosphatidylethanol.

Stenton J, Walther L, Hansson T, Andersson A, Isaksson A.

Alcohol Clin Exp Res. 2019 Nov;43(11):2322-2331. doi: 10.1111/acer.14195. Epub 2019 Sep 27.


Physical Activity and Sports-Real Health Benefits: A Review with Insight into the Public Health of Sweden.

Malm C, Jakobsson J, Isaksson A.

Sports (Basel). 2019 May 23;7(5). pii: E127. doi: 10.3390/sports7050127. Review.


Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.

Binzer-Panchal A, Hardell E, Viklund B, Ghaderi M, Bosse T, Nucci MR, Lee CH, Hollfelder N, Corcoran P, Gonzalez-Molina J, Moyano-Galceran L, Bell DA, Schoolmeester JK, Måsbäck A, Kristensen GB, Davidson B, Lehti K, Isaksson A, Carlson JW.

Clin Cancer Res. 2019 Apr 1;25(7):2155-2165. doi: 10.1158/1078-0432.CCR-18-2792. Epub 2019 Jan 7.


Environmental considerations in the Swedish building and construction industry: the role of costs, institutional setting, and information.

Isaksson A, Linderoth H.

J Hous Built Environ. 2018;33(4):615-632. doi: 10.1007/s10901-017-9588-8. Epub 2018 Jan 23.


Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein.

Danesi C, Achuta VS, Corcoran P, Peteri UK, Turconi G, Matsui N, Albayrak I, Rezov V, Isaksson A, Castrén ML.

Stem Cell Reports. 2018 Dec 11;11(6):1449-1461. doi: 10.1016/j.stemcr.2018.11.003. Epub 2018 Nov 29.


Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years.

Hofvander J, Viklund B, Isaksson A, Brosjö O, Vult von Steyern F, Rissler P, Mandahl N, Mertens F.

Nat Commun. 2018 Sep 10;9(1):3662. doi: 10.1038/s41467-018-06098-0.


Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer.

Karlsson J, Valind A, Holmquist Mengelbier L, Bredin S, Cornmark L, Jansson C, Wali A, Staaf J, Viklund B, Øra I, Börjesson A, Backman T, Braekeveldt N, Sandstedt B, Pal N, Isaksson A, Lackner BG, Jonson T, Bexell D, Gisselsson D.

Nat Genet. 2018 Jul;50(7):944-950. doi: 10.1038/s41588-018-0131-y. Epub 2018 Jun 4.


A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial.

Otten J, Stomby A, Waling M, Isaksson A, Söderström I, Ryberg M, Svensson M, Hauksson J, Olsson T.

Diabetologia. 2018 Jul;61(7):1548-1559. doi: 10.1007/s00125-018-4618-y. Epub 2018 Apr 26.


Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia.

Gunnarsson R, Dilorenzo S, Lundin-Ström KB, Olsson L, Biloglav A, Lilljebjörn H, Rissler M, Wahlberg P, Lundmark A, Castor A, Behrendtz M, Fioretos T, Paulsson K, Isaksson A, Johansson B.

Leukemia. 2018 Oct;32(10):2117-2125. doi: 10.1038/s41375-018-0092-2. Epub 2018 Mar 12.


Alcohol Consumption in Obese Patients Before and After Gastric Bypass as Assessed with the Alcohol Marker Phosphatidylethanol (PEth).

Walther L, Brodén CM, Isaksson A, Hedenbro JL.

Obes Surg. 2018 Aug;28(8):2354-2360. doi: 10.1007/s11695-018-3165-4.


Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages.

Baskaran S, Mayrhofer M, Kultima HG, Bergström T, Elfineh L, Cavelier L, Isaksson A, Nelander S.

Neuro Oncol. 2018 Jul 5;20(8):1080-1091. doi: 10.1093/neuonc/noy024.


Impact of Thyroid Autoimmunity on Thyroid Function in 12-year-old Children With Celiac Disease.

Norström F, van der Pals M, Myléus A, Hammarroth S, Högberg L, Isaksson A, Ivarsson A, Carlsson A.

J Pediatr Gastroenterol Nutr. 2018 Jul;67(1):64-68. doi: 10.1097/MPG.0000000000001903.


Scattered genomic amplification in dedifferentiated liposarcoma.

Mandahl N, Magnusson L, Nilsson J, Viklund B, Arbajian E, von Steyern FV, Isaksson A, Mertens F.

Mol Cytogenet. 2017 Jun 24;10:25. doi: 10.1186/s13039-017-0325-5. eCollection 2017.


Coping with stigma and discrimination: evidence from mental health service users in England.

Isaksson A, Corker E, Cotney J, Hamilton S, Pinfold V, Rose D, Rüsch N, Henderson C, Thornicroft G, Evans-Lacko S.

Epidemiol Psychiatr Sci. 2018 Dec;27(6):577-588. doi: 10.1017/S204579601700021X. Epub 2017 May 2.


Social identity shapes stress appraisals in people with a history of depression.

Isaksson A, Martin P, Kaufmehl J, Heinrichs M, Domes G, Rüsch N.

Psychiatry Res. 2017 Aug;254:12-17. doi: 10.1016/j.psychres.2017.04.021. Epub 2017 Apr 12.


Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia.

Kalikstad B, Kultima HG, Andersstuen TK, Klungland A, Isaksson A.

Mol Med Rep. 2017 Apr;15(4):1513-1526. doi: 10.3892/mmr.2017.6185. Epub 2017 Feb 8.


Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.

Mathot L, Kundu S, Ljungström V, Svedlund J, Moens L, Adlerteg T, Falk-Sörqvist E, Rendo V, Bellomo C, Mayrhofer M, Cortina C, Sundström M, Micke P, Botling J, Isaksson A, Moustakas A, Batlle E, Birgisson H, Glimelius B, Nilsson M, Sjöblom T.

Cancer Res. 2017 Apr 1;77(7):1730-1740. doi: 10.1158/0008-5472.CAN-16-1921. Epub 2017 Jan 20.


Rawcopy: Improved copy number analysis with Affymetrix arrays.

Mayrhofer M, Viklund B, Isaksson A.

Sci Rep. 2016 Oct 31;6:36158. doi: 10.1038/srep36158.


Prevalence of autism and attention-deficit-hyperactivity disorder in Down syndrome: a population-based study.

Oxelgren UW, Myrelid Å, Annerén G, Ekstam B, Göransson C, Holmbom A, Isaksson A, Åberg M, Gustafsson J, Fernell E.

Dev Med Child Neurol. 2017 Mar;59(3):276-283. doi: 10.1111/dmcn.13217. Epub 2016 Aug 9.


Benefits of a Paleolithic diet with and without supervised exercise on fat mass, insulin sensitivity, and glycemic control: a randomized controlled trial in individuals with type 2 diabetes.

Otten J, Stomby A, Waling M, Isaksson A, Tellström A, Lundin-Olsson L, Brage S, Ryberg M, Svensson M, Olsson T.

Diabetes Metab Res Rev. 2017 Jan;33(1). doi: 10.1002/dmrr.2828. Epub 2016 Jun 30.


Autistic traits and empathy in chronic vs. episodic depression.

Domes G, Spenthof I, Radtke M, Isaksson A, Normann C, Heinrichs M.

J Affect Disord. 2016 May;195:144-7. doi: 10.1016/j.jad.2016.02.006. Epub 2016 Feb 8.


Phosphatidylethanol is superior to carbohydrate-deficient transferrin and γ-glutamyltransferase as an alcohol marker and is a reliable estimate of alcohol consumption level.

Walther L, de Bejczy A, Löf E, Hansson T, Andersson A, Guterstam J, Hammarberg A, Asanovska G, Franck J, Söderpalm B, Isaksson A.

Alcohol Clin Exp Res. 2015 Nov;39(11):2200-8. doi: 10.1111/acer.12883.


Symptoms and self-care strategies during and six months after radiotherapy for prostate cancer - Scoping the perspectives of patients, professionals and literature.

Blomberg K, Wengström Y, Sundberg K, Browall M, Isaksson AK, Nyman MH, Langius-Eklöf A.

Eur J Oncol Nurs. 2016 Apr;21:139-45. doi: 10.1016/j.ejon.2015.09.004. Epub 2015 Oct 21.


Varenicline for treatment of alcohol dependence: a randomized, placebo-controlled trial.

de Bejczy A, Löf E, Walther L, Guterstam J, Hammarberg A, Asanovska G, Franck J, Isaksson A, Söderpalm B.

Alcohol Clin Exp Res. 2015 Nov;39(11):2189-99. doi: 10.1111/acer.12854. Epub 2015 Sep 28.


Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Crona J, Backman S, Maharjan R, Mayrhofer M, Stålberg P, Isaksson A, Hellman P, Björklund P.

Clin Cancer Res. 2015 Oct 1;21(19):4451-60. doi: 10.1158/1078-0432.CCR-14-2854. Epub 2015 May 19.


Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.

Birgisson H, Edlund K, Wallin U, Påhlman L, Kultima HG, Mayrhofer M, Micke P, Isaksson A, Botling J, Glimelius B, Sundström M.

BMC Cancer. 2015 Mar 14;15:125. doi: 10.1186/s12885-015-1144-x.


Phosphatidylethanol Compared with Other Blood Tests as a Biomarker of Moderate Alcohol Consumption in Healthy Volunteers: A Prospective Randomized Study.

Kechagias S, Dernroth DN, Blomgren A, Hansson T, Isaksson A, Walther L, Kronstrand R, Kågedal B, Nystrom FH.

Alcohol Alcohol. 2015 Jul;50(4):399-406. doi: 10.1093/alcalc/agv038. Epub 2015 Apr 15.


Feasibility of an interactive ICT-platform for early assessment and management of patient-reported symptoms during radiotherapy for prostate cancer.

Sundberg K, Eklöf AL, Blomberg K, Isaksson AK, Wengström Y.

Eur J Oncol Nurs. 2015 Oct;19(5):523-8. doi: 10.1016/j.ejon.2015.02.013. Epub 2015 Mar 23.


Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers.

Watkins J, Weekes D, Shah V, Gazinska P, Joshi S, Sidhu B, Gillett C, Pinder S, Vanoli F, Jasin M, Mayrhofer M, Isaksson A, Cheang MC, Mirza H, Frankum J, Lord CJ, Ashworth A, Vinayak S, Ford JM, Telli ML, Grigoriadis A, Tutt AN.

Cancer Discov. 2015 May;5(5):488-505. doi: 10.1158/2159-8290.CD-14-1092. Epub 2015 Mar 13.


Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

Mengelbier LH, Karlsson J, Lindgren D, Valind A, Lilljebjörn H, Jansson C, Bexell D, Braekeveldt N, Ameur A, Jonson T, Kultima HG, Isaksson A, Asmundsson J, Versteeg R, Rissler M, Fioretos T, Sandstedt B, Börjesson A, Backman T, Pal N, Øra I, Mayrhofer M, Gisselsson D.

Nat Commun. 2015 Jan 27;6:6125. doi: 10.1038/ncomms7125.


Work stress among newly graduated nurses in relation to workplace and clinical group supervision.

Blomberg K, Isaksson AK, Allvin R, Bisholt B, Ewertsson M, Kullén Engström A, Ohlsson U, Sundler Johansson A, Gustafsson M.

J Nurs Manag. 2016 Jan;24(1):80-7. doi: 10.1111/jonm.12274. Epub 2014 Nov 25.


1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer.

Mayrhofer M, Kultima HG, Birgisson H, Sundström M, Mathot L, Edlund K, Viklund B, Sjöblom T, Botling J, Micke P, Påhlman L, Glimelius B, Isaksson A.

BMC Cancer. 2014 Nov 24;14:872. doi: 10.1186/1471-2407-14-872.


Serum neuron specific enolase - impact of storage and measuring method.

Rundgren M, Cronberg T, Friberg H, Isaksson A.

BMC Res Notes. 2014 Oct 15;7:726. doi: 10.1186/1756-0500-7-726.


Differentiation and quantification of synthetic phosphatidylethanol (PEth) homologues by ¹H- and ¹³C-NMR in polar organic solvents.

Wensbo Posaric D, Andersson A, Bergquist KE, Isaksson A.

Anal Bioanal Chem. 2014 Jul;406(19):4735-44. doi: 10.1007/s00216-014-7826-4. Epub 2014 May 28.


Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks - Evidence of a Tail Biting Resistant Phenotype.

Brunberg E, Jensen P, Isaksson A, Keeling LJ.

PLoS One. 2013 Jun 18;8(6):e66513. doi: 10.1371/journal.pone.0066513. Print 2013.


Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines.

Sooman L, Ekman S, Andersson C, Kultima HG, Isaksson A, Johansson F, Bergqvist M, Blomquist E, Lennartsson J, Gullbo J.

Cancer Chemother Pharmacol. 2013 Aug;72(2):329-40. doi: 10.1007/s00280-013-2197-7. Epub 2013 Jun 5.


Patients' experiences of bladder emptying in connection with hip surgery: an issue but of varying impact.

Nyman MH, Gustafsson M, Langius-Eklöf A, Isaksson AK.

J Adv Nurs. 2013 Dec;69(12):2686-95. doi: 10.1111/jan.12156. Epub 2013 Apr 24.


Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue.

Mayrhofer M, DiLorenzo S, Isaksson A.

Genome Biol. 2013 Mar 25;14(3):R24. doi: 10.1186/gb-2013-14-3-r24.


Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles.

Kanduri M, Marincevic M, Halldórsdóttir AM, Mansouri L, Junevik K, Ntoufa S, Kultima HG, Isaksson A, Juliusson G, Andersson PO, Ehrencrona H, Stamatopoulos K, Rosenquist R.

Epigenetics. 2012 Dec 1;7(12):1435-42. doi: 10.4161/epi.22901. Epub 2012 Nov 15.


Brain gene expression differences are associated with abnormal tail biting behavior in pigs.

Brunberg E, Jensen P, Isaksson A, Keeling LJ.

Genes Brain Behav. 2013 Mar;12(2):275-81. doi: 10.1111/gbb.12002. Epub 2012 Dec 7.


[Equalis/SFKK recommends harmonization of units in hormone determinations for safer care].

Brattsand G, Nordin G, Isaksson A, Bjellerup P, Stridsberg M, Hård L, Ankarberg-Lindgren C, Becker C, Gustafsson S, Larsson K.

Lakartidningen. 2012 Sep 26-Oct 9;109(39-40):1773. Swedish. No abstract available.


Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease.

Skirnisdottir I, Mayrhofer M, Rydåker M, Akerud H, Isaksson A.

BMC Cancer. 2012 Sep 12;12:407. doi: 10.1186/1471-2407-12-407.


450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.

Cahill N, Bergh AC, Kanduri M, Göransson-Kultima H, Mansouri L, Isaksson A, Ryan F, Smedby KE, Juliusson G, Sundström C, Rosén A, Rosenquist R.

Leukemia. 2013 Jan;27(1):150-8. doi: 10.1038/leu.2012.245. Epub 2012 Aug 27.


Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia.

Mansouri L, Gunnarsson R, Sutton LA, Ameur A, Hooper SD, Mayrhofer M, Juliusson G, Isaksson A, Gyllensten U, Rosenquist R.

Am J Hematol. 2012 Jul;87(7):737-40. doi: 10.1002/ajh.23227. Epub 2012 Jun 3.


[Wrong diagnostic code makes the follow up of pregnant women's sick leave more difficult].

Karnehed N, Osterlund N, Isaksson AK, Nyman M, Sparre LS, Ljung R.

Lakartidningen. 2012 Jan 25-31;109(4):168. Swedish. No abstract available.


CD99 is a novel prognostic stromal marker in non-small cell lung cancer.

Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P.

Int J Cancer. 2012 Nov 15;131(10):2264-73. doi: 10.1002/ijc.27518. Epub 2012 Apr 24.


Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.

Halldórsdóttir AM, Kanduri M, Marincevic M, Mansouri L, Isaksson A, Göransson H, Axelsson T, Agarwal P, Jernberg-Wiklund H, Stamatopoulos K, Sander B, Ehrencrona H, Rosenquist R.

Am J Hematol. 2012 Apr;87(4):361-7. doi: 10.1002/ajh.23115. Epub 2012 Feb 28.

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