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The development of a family resilience-strengthening programme for families in a South African rural community.

Isaacs SA, Roman NV, Savahl S.

J Community Psychol. 2018 Jul;46(5):616-635. doi: 10.1002/jcop.21962. Epub 2018 Mar 14.


Early-life factors contributing to type 1 diabetes.

Craig ME, Kim KW, Isaacs SR, Penno MA, Hamilton-Williams EE, Couper JJ, Rawlinson WD.

Diabetologia. 2019 Oct;62(10):1823-1834. doi: 10.1007/s00125-019-4942-x. Epub 2019 Aug 27. Review.


HIV-1 DNA decay is faster in children who initiate ART shortly after birth than later.

Veldsman KA, Janse van Rensburg A, Isaacs S, Naidoo S, Laughton B, Lombard C, Cotton MF, Mellors JW, van Zyl GU.

J Int AIDS Soc. 2019 Aug;22(8):e25368. doi: 10.1002/jia2.25368.


Resonant Grating without a Planar Waveguide Layer as a Refractive Index Sensor.

Isaacs S, Hajoj A, Abutoama M, Kozlovsky A, Golan E, Abdulhalim I.

Sensors (Basel). 2019 Jul 8;19(13). pii: E3003. doi: 10.3390/s19133003.


Preventing Diabetes in the Workplace: Effects of Coaching and Monetary Incentives.

Raymond LW, Roy DM, Mullinax SL, Yanni A, Pentek KC, Isaacs SE.

J Occup Environ Med. 2019 Jul;61(7):e308-e311. doi: 10.1097/JOM.0000000000001611.


Improved Detection of Plasmon Waveguide Resonance Using Diverging Beam, Liquid Crystal Retarder, and Application to Lipid Orientation Determination.

Isaacs S, Harté E, Alves ID, Abdulhalim I.

Sensors (Basel). 2019 Mar 21;19(6). pii: E1402. doi: 10.3390/s19061402.


Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study.

Wook Kim K, Allen DW, Briese T, Couper JJ, Barry SC, Colman PG, Cotterill AM, Davis EA, Giles LC, Harrison LC, Harris M, Haynes A, Horton JL, Isaacs SR, Jain K, Lipkin WI, Morahan G, Morbey C, Pang ICN, Papenfuss AT, Penno MAS, Sinnott RO, Soldatos G, Thomson RL, Vuillermin PJ, Wentworth JM, Wilkins MR, Rawlinson WD, Craig ME; ENDIA Study Group.

Open Forum Infect Dis. 2019 Jan 16;6(2):ofz025. doi: 10.1093/ofid/ofz025. eCollection 2019 Feb.


Higher abundance of enterovirus A species in the gut of children with islet autoimmunity.

Kim KW, Horton JL, Pang CNI, Jain K, Leung P, Isaacs SR, Bull RA, Luciani F, Wilkins MR, Catteau J, Lipkin WI, Rawlinson WD, Briese T, Craig ME.

Sci Rep. 2019 Feb 11;9(1):1749. doi: 10.1038/s41598-018-38368-8.


The John A. Hartford Foundation And The Growth Of Geriatrics.

Isaacs S, Jellinek PS, Fulmer T.

Health Aff (Millwood). 2019 Jan;38(1):164-168. doi: 10.1377/hlthaff.2018.05297.


Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor.

Nuth M, Guan H, Xiao Y, Kulp JL 3rd, Parker MH, Strobel ED, Isaacs SN, Scott RW, Reitz AB, Ricciardi RP.

Antiviral Res. 2019 Feb;162:178-185. doi: 10.1016/j.antiviral.2018.12.011. Epub 2018 Dec 20.


Social capital and self-rated health: A cross-sectional study of the general social survey data comparing rural and urban adults in Ontario.

Buck-McFadyen E, Akhtar-Danesh N, Isaacs S, Leipert B, Strachan P, Valaitis R.

Health Soc Care Community. 2019 Mar;27(2):424-436. doi: 10.1111/hsc.12662. Epub 2018 Sep 30.


Berry Brazelton and Cats.

Isaacs D, Isaacs S.

J Paediatr Child Health. 2018 Aug;54(8):928. doi: 10.1111/jpc.14132. No abstract available.


Amplification and next generation sequencing of near full-length human enteroviruses for identification and characterisation from clinical samples.

Isaacs SR, Kim KW, Cheng JX, Bull RA, Stelzer-Braid S, Luciani F, Rawlinson WD, Craig ME.

Sci Rep. 2018 Aug 8;8(1):11889. doi: 10.1038/s41598-018-30322-y.


Quantitative assessment of paraoxon adsorption to amphiphilic β-sheet peptides presenting the catalytic triad of esterases.

Baruch Leshem A, Isaacs S, Srivastava SK, Abdulhalim I, Kushmaro A, Rapaport H.

J Colloid Interface Sci. 2018 Nov 15;530:328-337. doi: 10.1016/j.jcis.2018.06.065. Epub 2018 Jun 23.


Rapid decline of HIV-1 DNA and RNA in infants starting very early antiretroviral therapy may pose a diagnostic challenge.

Veldsman KA, Maritz J, Isaacs S, Katusiime MG, Janse van Rensburg A, Laughton B, Mellors JW, Cotton MF, van Zyl GU.

AIDS. 2018 Mar 13;32(5):629-634. doi: 10.1097/QAD.0000000000001739.


Dallas MegaShelter Medical Operations Response to Hurricane Harvey.

Liu EL, Morshedi B, Miller BL, Miller R, Isaacs SM, Fowler RL, Chung W, Blum R, Ward B, Carlo J, Hennes H, Webster F, Perl T, Noah C, Monaghan R, Tran AH, Benitez F, Graves J, Kibbey C, Klein KR, Swienton RE.

Disaster Med Public Health Prep. 2019 Feb;13(1):90-93. doi: 10.1017/dmp.2017.123. Epub 2017 Dec 6.


Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women.

Sarnowski C, Kavousi M, Isaacs S, Demerath EW, Broer L, Muka T, Franco OH, Ikram MA, Uitterlinden A, Franceschini N, Lunetta KL, Murabito JM.

Menopause. 2018 Apr;25(4):451-457. doi: 10.1097/GME.0000000000001017.


Identifying Host Factors Associated with DNA Replicated During Virus Infection.

Reyes ED, Kulej K, Pancholi NJ, Akhtar LN, Avgousti DC, Kim ET, Bricker DK, Spruce LA, Koniski SA, Seeholzer SH, Isaacs SN, Garcia BA, Weitzman MD.

Mol Cell Proteomics. 2017 Dec;16(12):2079-2097. doi: 10.1074/mcp.M117.067116. Epub 2017 Oct 2.


Contact Angle and Adhesion Dynamics and Hysteresis on Molecularly Smooth Chemically Homogeneous Surfaces.

Chen SY, Kaufman Y, Schrader AM, Seo D, Lee DW, Page SH, Koenig PH, Isaacs S, Gizaw Y, Israelachvili JN.

Langmuir. 2017 Sep 26;33(38):10041-10050. doi: 10.1021/acs.langmuir.7b02075. Epub 2017 Aug 29.


US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.


Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers.

Lotan TL, Torres A, Zhang M, Tosoian JJ, Guedes LB, Fedor H, Hicks J, Ewing CM, Isaacs SD, Johng D, De Marzo AM, Isaacs WB.

Oncotarget. 2017 Apr 4;8(14):22772-22782. doi: 10.18632/oncotarget.15196.


Adapting and Validating the Family Resilience Assessment Scale in an Afrikaans Rural Community in South Africa.

Isaacs SA, Roman NV, Savahl S, Sui XC.

Community Ment Health J. 2018 Jan;54(1):73-83. doi: 10.1007/s10597-017-0091-1. Epub 2017 Feb 1.


Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death.

Na R, Zheng SL, Han M, Yu H, Jiang D, Shah S, Ewing CM, Zhang L, Novakovic K, Petkewicz J, Gulukota K, Helseth DL Jr, Quinn M, Humphries E, Wiley KE, Isaacs SD, Wu Y, Liu X, Zhang N, Wang CH, Khandekar J, Hulick PJ, Shevrin DH, Cooney KA, Shen Z, Partin AW, Carter HB, Carducci MA, Eisenberger MA, Denmeade SR, McGuire M, Walsh PC, Helfand BT, Brendler CB, Ding Q, Xu J, Isaacs WB.

Eur Urol. 2017 May;71(5):740-747. doi: 10.1016/j.eururo.2016.11.033. Epub 2016 Dec 15.


MicroRNAs in Type 1 Diabetes: Complex Interregulation of the Immune System, β Cell Function and Viral Infections.

Isaacs SR, Wang J, Kim KW, Yin C, Zhou L, Mi QS, Craig ME.

Curr Diab Rep. 2016 Dec;16(12):133. Review.


Over-expression of insulin-response element binding protein-1 (IRE-BP1) in mouse pancreatic islets increases expression of RACK1 and TCTP: Beta cell markers of high glucose sensitivity.

Villafuerte BC, Barati MT, Rane MJ, Isaacs S, Li M, Wilkey DW, Merchant ML.

Biochim Biophys Acta Proteins Proteom. 2017 Feb;1865(2):186-194. doi: 10.1016/j.bbapap.2016.10.015. Epub 2016 Nov 3.


Detectable Tenofovir Levels in Breast-Feeding Infants of Mothers Exposed to Topical Tenofovir.

Noguchi LM, Montgomery ET, Biggio JR, Hendrix CW, Bogen DL, Hillier SL, Dai JY, Piper JM, Marzinke MA, Dezzutti CS, Isaacs SK, Schwartz JL, Watts DH, Beigi RH.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5616-9. doi: 10.1128/AAC.00645-16. Print 2016 Sep.


Designing, Implementing, and Evaluating Mobile Health Technologies for Managing Chronic Conditions in Older Adults: A Scoping Review.

Matthew-Maich N, Harris L, Ploeg J, Markle-Reid M, Valaitis R, Ibrahim S, Gafni A, Isaacs S.

JMIR Mhealth Uhealth. 2016 Jun 9;4(2):e29. doi: 10.2196/mhealth.5127. Review.


Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.

Teerlink CC, Leongamornlert D, Dadaev T, Thomas A, Farnham J, Stephenson RA, Riska S, McDonnell SK, Schaid DJ, Catalona WJ, Zheng SL, Cooney KA, Ray AM, Zuhlke KA, Lange EM, Giles GG, Southey MC, Fitzgerald LM, Rinckleb A, Luedeke M, Maier C, Stanford JL, Ostrander EA, Kaikkonen EM, Sipeky C, Tammela T, Schleutker J, Wiley KE, Isaacs SD, Walsh PC, Isaacs WB, Xu J, Cancel-Tassin G, Cussenot O, Mandal D, Laurie C, Laurie C; PRACTICAL consortium; International Consortium for Prostate Cancer Genetics, Thibodeau SN, Eeles RA, Kote-Jarai Z, Cannon-Albright L.

Hum Genet. 2016 Aug;135(8):923-38. doi: 10.1007/s00439-016-1690-6. Epub 2016 Jun 4.


Influence of Acute High Glucose on Protein Abundance Changes in Murine Glomerular Mesangial Cells.

Barati MT, Gould JC, Salyer SA, Isaacs S, Wilkey DW, Merchant ML.

J Diabetes Res. 2016;2016:3537863. doi: 10.1155/2016/3537863. Epub 2015 Dec 29.


MEMEs: modern evolutionary medical euphemisms.

Isaacs D, Isaacs S, Fitzgerald D.

BMJ. 2015 Dec 11;351:h6107. doi: 10.1136/bmj.h6107. No abstract available.


Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice.

Barati MT, Powell DW, Kechavarzi BD, Isaacs SM, Zheng S, Epstein PN, Cai L, Coventry S, Rane MJ, Klein JB.

Cell Stress Chaperones. 2016 Jan;21(1):155-166. doi: 10.1007/s12192-015-0648-2.


Influence of statins on distinct circulating microRNAs during prolonged aerobic exercise.

Min PK, Park J, Isaacs S, Taylor BA, Thompson PD, Troyanos C, D'Hemecourt P, Dyer S, Chan SY, Baggish AL.

J Appl Physiol (1985). 2016 Mar 15;120(6):711-20. doi: 10.1152/japplphysiol.00654.2015. Epub 2015 Oct 15.


Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer.

Hurley PJ, Sundi D, Shinder B, Simons BW, Hughes RM, Miller RM, Benzon B, Faraj SF, Netto GJ, Vergara IA, Erho N, Davicioni E, Karnes RJ, Yan G, Ewing C, Isaacs SD, Berman DM, Rider JR, Jordahl KM, Mucci LA, Huang J, An SS, Park BH, Isaacs WB, Marchionni L, Ross AE, Schaeffer EM.

Clin Cancer Res. 2016 Jan 15;22(2):448-58. doi: 10.1158/1078-0432.CCR-15-0256. Epub 2015 Oct 7.


Ruptured Tendons in Anabolic-Androgenic Steroid Users: A Cross-Sectional Cohort Study.

Kanayama G, DeLuca J, Meehan WP 3rd, Hudson JI, Isaacs S, Baggish A, Weiner R, Micheli L, Pope HG Jr.

Am J Sports Med. 2015 Nov;43(11):2638-44. doi: 10.1177/0363546515602010. Epub 2015 Sep 11.


Myocardial adaptations to recreational marathon training among middle-aged men.

Zilinski JL, Contursi ME, Isaacs SK, Deluca JR, Lewis GD, Weiner RB, Hutter AM Jr, d'Hemecourt PA, Troyanos C, Dyer KS, Baggish AL.

Circ Cardiovasc Imaging. 2015 Feb;8(2):e002487. doi: 10.1161/CIRCIMAGING.114.002487.


Prolonged hypogonadism in males following withdrawal from anabolic-androgenic steroids: an under-recognized problem.

Kanayama G, Hudson JI, DeLuca J, Isaacs S, Baggish A, Weiner R, Bhasin S, Pope HG Jr.

Addiction. 2015 May;110(5):823-31. doi: 10.1111/add.12850. Epub 2015 Feb 25.


A Christmas carousel.

Isaacs S, Isaacs D.

BMJ. 2014 Dec 16;349:g7444. doi: 10.1136/bmj.g7444. No abstract available.


Combination antiretroviral therapy reduces the detection risk of cervical human papilloma virus infection in women living with HIV.

Zeier MD, Botha MH, Engelbrecht S, Machekano RN, Jacobs GB, Isaacs S, van Schalkwyk M, van der Merwe H, Mason D, Nachega JB.

AIDS. 2015 Jan 2;29(1):59-66. doi: 10.1097/QAD.0000000000000512.


Transitional objects and thumb sucking.

Isaacs D, Isaacs S.

J Paediatr Child Health. 2014 Nov;50(11):845-6. doi: 10.1111/jpc.12747. No abstract available.


Community health nurses' learning needs in relation to the Canadian community health nursing standards of practice: results from a Canadian survey.

Valaitis RK, Schofield R, Akhtar-Danesh N, Baumann A, Martin-Misener R, Underwood J, Isaacs S.

BMC Nurs. 2014 Oct 21;13:31. doi: 10.1186/1472-6955-13-31. eCollection 2014.


Investigation of liquid crystal Fabry-Perot tunable filters: design, fabrication, and polarization independence.

Isaacs S, Placido F, Abdulhalim I.

Appl Opt. 2014 Oct 10;53(29):H91-101. doi: 10.1364/AO.53.000H91.


A novel target and approach for identifying antivirals against molluscum contagiosum virus.

Guan H, Nuth M, Zhukovskaya N, Saw YL, Bell E, Isaacs SN, Ricciardi RP.

Antimicrob Agents Chemother. 2014 Dec;58(12):7383-9. doi: 10.1128/AAC.03660-14. Epub 2014 Sep 29.


Six weeks daily ingestion of whole blueberry powder increases natural killer cell counts and reduces arterial stiffness in sedentary males and females.

McAnulty LS, Collier SR, Landram MJ, Whittaker DS, Isaacs SE, Klemka JM, Cheek SL, Arms JC, McAnulty SR.

Nutr Res. 2014 Jul;34(7):577-84. doi: 10.1016/j.nutres.2014.07.002. Epub 2014 Jul 8.


Analysis of substrate degradation, metabolite formation and microbial community responses in sand bioreactors treating winery wastewater: a comparative study.

Welz PJ, Palmer Z, Isaacs S, Kirby B, le Roes-Hill M.

J Environ Manage. 2014 Dec 1;145:147-56. doi: 10.1016/j.jenvman.2014.06.025. Epub 2014 Jul 12.


Impact of statin use on exercise-induced cardiac troponin elevations.

Eijsvogels TM, Januzzi JL, Taylor BA, Isaacs SK, D'Hemecourt P, Zaleski A, Dyer S, Troyanos C, Weiner RB, Thompson PD, Baggish AL.

Am J Cardiol. 2014 Aug 15;114(4):624-8. doi: 10.1016/j.amjcard.2014.05.047. Epub 2014 Jun 6.


HIV-1 subtypes B and C unique recombinant forms (URFs) and transmitted drug resistance identified in the Western Cape Province, South Africa.

Jacobs GB, Wilkinson E, Isaacs S, Spies G, de Oliveira T, Seedat S, Engelbrecht S.

PLoS One. 2014 Mar 7;9(6):e90845. doi: 10.1371/journal.pone.0090845. eCollection 2014.


Rapid upregulation and clearance of distinct circulating microRNAs after prolonged aerobic exercise.

Baggish AL, Park J, Min PK, Isaacs S, Parker BA, Thompson PD, Troyanos C, D'Hemecourt P, Dyer S, Thiel M, Hale A, Chan SY.

J Appl Physiol (1985). 2014 Mar 1;116(5):522-31. doi: 10.1152/japplphysiol.01141.2013. Epub 2014 Jan 16.


The Da Vinci Code and the alphabet of research.

Fitzgerald DA, Isaacs D, Isaacs S.

Med J Aust. 2013 Dec 16;199(11):816. No abstract available.


Telomere length as a risk factor for hereditary prostate cancer.

Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK.

Prostate. 2014 Apr;74(4):359-64. doi: 10.1002/pros.22755. Epub 2013 Nov 28.

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