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Items: 1 to 50 of 145

1.

Acyclic Cucurbit[n]uril-type Receptors: Preparation, Molecular Recognition Properties and Biological Applications.

Ganapati S, Isaacs L.

Isr J Chem. 2018 Apr;58(3-4):250-263. doi: 10.1002/ijch.201700098. Epub 2017 Nov 14.

PMID:
29805180
2.

Blurring the Lines between Host and Guest: A Chimeric Receptor Derived from Cucurbituril and Triptycene.

Lu X, Samanta SK, Zavalij PY, Isaacs L.

Angew Chem Int Ed Engl. 2018 Jul 2;57(27):8073-8078. doi: 10.1002/anie.201803132. Epub 2018 May 30.

PMID:
29749674
3.

Shape-Controllable and Fluorescent Supramolecular Organic Frameworks Through Aqueous Host-Guest Complexation.

Li Y, Dong Y, Miao X, Ren Y, Zhang B, Wang P, Yu Y, Li B, Isaacs L, Cao L.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):729-733. doi: 10.1002/anie.201710553. Epub 2017 Dec 14.

PMID:
29193530
4.

Host-Guest Tethered DNA Transducer: ATP Fueled Release of a Protein Inhibitor from Cucurbit[7]uril.

Zhou X, Su X, Pathak P, Vik R, Vinciguerra B, Isaacs L, Jayawickramarajah J.

J Am Chem Soc. 2017 Oct 4;139(39):13916-13921. doi: 10.1021/jacs.7b07977. Epub 2017 Sep 20.

PMID:
28882044
5.

Supramolecular Sensors for Opiates and Their Metabolites.

Shcherbakova EG, Zhang B, Gozem S, Minami T, Zavalij PY, Pushina M, Isaacs LD, Anzenbacher P Jr.

J Am Chem Soc. 2017 Oct 25;139(42):14954-14960. doi: 10.1021/jacs.7b06371. Epub 2017 Sep 8.

PMID:
28820934
6.

Cucurbit[7]uril Enables Multi-Stimuli-Responsive Release from the Self-Assembled Hydrophobic Phase of a Metal Organic Polyhedron.

Samanta SK, Quigley J, Vinciguerra B, Briken V, Isaacs L.

J Am Chem Soc. 2017 Jul 5;139(26):9066-9074. doi: 10.1021/jacs.7b05154. Epub 2017 Jun 23.

7.

Molecular Containers Bind Drugs of Abuse in Vitro and Reverse the Hyperlocomotive Effect of Methamphetamine in Rats.

Ganapati S, Grabitz SD, Murkli S, Scheffenbichler F, Rudolph MI, Zavalij PY, Eikermann M, Isaacs L.

Chembiochem. 2017 Aug 17;18(16):1583-1588. doi: 10.1002/cbic.201700289. Epub 2017 Jul 12.

PMID:
28586110
8.

Self-assembly of cucurbit[7]uril based triangular [4]molecular necklaces and their fluorescence properties.

Samanta SK, Brady KG, Isaacs L.

Chem Commun (Camb). 2017 Feb 28;53(18):2756-2759. doi: 10.1039/c6cc10328f.

9.

Synthetic mimics of biotin/(strept)avidin.

Liu W, Samanta SK, Smith BD, Isaacs L.

Chem Soc Rev. 2017 May 9;46(9):2391-2403. doi: 10.1039/c7cs00011a. Review.

10.

Unraveling the Structure-Affinity Relationship between Cucurbit[n]urils (n = 7, 8) and Cationic Diamondoids.

Sigwalt D, Šekutor M, Cao L, Zavalij PY, Hostaš J, Ajani H, Hobza P, Mlinarić-Majerski K, Glaser R, Isaacs L.

J Am Chem Soc. 2017 Mar 1;139(8):3249-3258. doi: 10.1021/jacs.7b00056. Epub 2017 Feb 21.

PMID:
28182422
11.

Cucurbit[7]uril-Tetramethylrhodamine Conjugate for Direct Sensing and Cellular Imaging.

Bockus AT, Smith LC, Grice AG, Ali OA, Young CC, Mobley W, Leek A, Roberts JL, Vinciguerra B, Isaacs L, Urbach AR.

J Am Chem Soc. 2016 Dec 21;138(50):16549-16552. doi: 10.1021/jacs.6b11140. Epub 2016 Dec 8.

PMID:
27998093
12.

Supramolecular PEGylation of biopharmaceuticals.

Webber MJ, Appel EA, Vinciguerra B, Cortinas AB, Thapa LS, Jhunjhunwala S, Isaacs L, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14189-14194. Epub 2016 Nov 28.

13.

From Packed "Sandwich" to "Russian Doll": Assembly by Charge-Transfer Interactions in Cucurbit[10]uril.

Gong W, Yang X, Zavalij PY, Isaacs L, Zhao Z, Liu S.

Chemistry. 2016 Dec 5;22(49):17612-17618. doi: 10.1002/chem.201604149. Epub 2016 Nov 8.

PMID:
27862408
14.

Metal-Organic Polyhedron Capped with Cucurbit[8]uril Delivers Doxorubicin to Cancer Cells.

Samanta SK, Moncelet D, Briken V, Isaacs L.

J Am Chem Soc. 2016 Nov 2;138(43):14488-14496. Epub 2016 Oct 20.

15.

Cationic acyclic cucurbit[n]uril-type containers: synthesis and molecular recognition toward nucleotides.

Sigwalt D, Zavalij PY, Isaacs L.

Supramol Chem. 2016;28(9-10):825-834. Epub 2016 Apr 13.

16.

A Nexus between Theory and Experiment: Non-Empirical Quantum Mechanical Computational Methodology Applied to Cucurbit[n]uril⋅Guest Binding Interactions.

Hostaš J, Sigwalt D, Šekutor M, Ajani H, Dubecký M, Řezáč J, Zavalij PY, Cao L, Wohlschlager C, Mlinarić-Majerski K, Isaacs L, Glaser R, Hobza P.

Chemistry. 2016 Nov 21;22(48):17226-17238. doi: 10.1002/chem.201601833. Epub 2016 Oct 10.

PMID:
27723181
17.

Dr Gonzalez as a Practice Colleague: A Memoir.

Isaacs LL.

Altern Ther Health Med. 2016 Jul;22(4):14-6.

PMID:
27548486
18.

Glycoluril-Derived Molecular Clips are Potent and Selective Receptors for Cationic Dyes in Water.

She N, Moncelet D, Gilberg L, Lu X, Sindelar V, Briken V, Isaacs L.

Chemistry. 2016 Oct 17;22(43):15270-15279. doi: 10.1002/chem.201601796. Epub 2016 Aug 5.

19.

A Novel Strategy to Reverse General Anesthesia by Scavenging with the Acyclic Cucurbit[n]uril-type Molecular Container Calabadion 2.

Diaz-Gil D, Haerter F, Falcinelli S, Ganapati S, Hettiarachchi GK, Simons JC, Zhang B, Grabitz SD, Moreno Duarte I, Cotten JF, Eikermann-Haerter K, Deng H, Chamberlin NL, Isaacs L, Briken V, Eikermann M.

Anesthesiology. 2016 Aug;125(2):333-45. doi: 10.1097/ALN.0000000000001199.

20.

Predictive recognition of native proteins by cucurbit[7]uril in a complex mixture.

Li W, Bockus AT, Vinciguerra B, Isaacs L, Urbach AR.

Chem Commun (Camb). 2016 Jun 30;52(55):8537-40. doi: 10.1039/c6cc03193e.

PMID:
27311878
21.

Uptake of Hydrocarbons in Aqueous Solution by Encapsulation in Acyclic Cucurbit[n]uril-Type Molecular Containers.

Lu X, Isaacs L.

Angew Chem Int Ed Engl. 2016 Jul 4;55(28):8076-80. doi: 10.1002/anie.201602671. Epub 2016 May 12.

PMID:
27169688
22.

Energy-resolved collision-induced dissociation of non-covalent ions: charge- and guest-dependence of decomplexation reaction efficiencies.

Carroy G, Lemaur V, De Winter J, Isaacs L, De Pauw E, Cornil J, Gerbaux P.

Phys Chem Chem Phys. 2016 May 14;18(18):12557-68. doi: 10.1039/c6cp01026a. Epub 2016 Apr 18.

PMID:
27086657
23.

Acyclic Cucurbit[n]uril-Type Molecular Containers: Influence of Linker Length on Their Function as Solubilizing Agents.

Sigwalt D, Moncelet D, Falcinelli S, Mandadapu V, Zavalij PY, Day A, Briken V, Isaacs L.

ChemMedChem. 2016 May 6;11(9):980-9. doi: 10.1002/cmdc.201600090. Epub 2016 Mar 15.

24.

A Changing World Through the Lens of Panama.

de Isaacs LG.

J Transcult Nurs. 2016 Mar;27(2):199-200. doi: 10.1177/1043659615625780. No abstract available.

PMID:
26868658
25.

Research Battles: Survival Tips From a Veteran.

Isaacs LL.

Integr Med (Encinitas). 2015 Oct;14(5):30-2.

26.

Acyclic Cucurbit[n]uril-Type Molecular Container Enables Systemic Delivery of Effective Doses of Albendazole for Treatment of SK-OV-3 Xenograft Tumors.

Hettiarachchi G, Samanta SK, Falcinelli S, Zhang B, Moncelet D, Isaacs L, Briken V.

Mol Pharm. 2016 Mar 7;13(3):809-18. doi: 10.1021/acs.molpharmaceut.5b00723. Epub 2016 Jan 22.

27.

In Vitro selectivity of an acyclic cucurbit[n]uril molecular container towards neuromuscular blocking agents relative to commonly used drugs.

Ganapati S, Zavalij PY, Eikermann M, Isaacs L.

Org Biomol Chem. 2016 Jan 28;14(4):1277-87. doi: 10.1039/c5ob02356d. Epub 2015 Dec 9.

28.

Acyclic Cucurbit[n]uril Dendrimers.

Sigwalt D, Ahlbrand S, Zhang M, Vinciguerra B, Briken V, Isaacs L.

Org Lett. 2015 Dec 4;17(23):5914-7. doi: 10.1021/acs.orglett.5b03145. Epub 2015 Nov 23.

29.

Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents.

Haerter F, Simons JC, Foerster U, Moreno Duarte I, Diaz-Gil D, Ganapati S, Eikermann-Haerter K, Ayata C, Zhang B, Blobner M, Isaacs L, Eikermann M.

Anesthesiology. 2015 Dec;123(6):1337-49. doi: 10.1097/ALN.0000000000000868.

30.

Synthesis and Recognition Properties of Cucurbit[8]uril Derivatives.

Vinciguerra B, Zavalij PY, Isaacs L.

Org Lett. 2015 Oct 16;17(20):5068-71. doi: 10.1021/acs.orglett.5b02558. Epub 2015 Sep 25.

PMID:
26405845
31.

Differentially functionalized acyclic cucurbiturils: synthesis, self-assembly and CB[6]-induced allosteric guest binding.

Zhang M, Sigwalt D, Isaacs L.

Chem Commun (Camb). 2015 Oct 7;51(78):14620-3. doi: 10.1039/c5cc05803a.

PMID:
26288859
32.

Synthesis and Recognition Properties of Enantiomerically Pure Acyclic Cucurbit[n]uril-Type Molecular Containers.

Lu X, Isaacs L.

Org Lett. 2015 Aug 21;17(16):4038-41. doi: 10.1021/acs.orglett.5b01948. Epub 2015 Aug 7.

PMID:
26251172
33.

Influence of hydrophobic residues on the binding of CB[7] toward diammonium ions of common ammonium···ammonium distance.

Cao L, Škalamera Đ, Zavalij PY, Hostaš J, Hobza P, Mlinarić-Majerski K, Glaser R, Isaacs L.

Org Biomol Chem. 2015 Jun 14;13(22):6249-54. doi: 10.1039/c5ob00784d.

PMID:
25962667
34.
35.

Statistics: why meaningful statistics cannot be generated from a private practice.

Gonzalez NJ, Isaacs LL.

Altern Ther Health Med. 2015 Mar-Apr;21(2):11-5. No abstract available.

PMID:
25830274
36.

Acyclic cucurbit[n]uril-type molecular containers: influence of glycoluril oligomer length on their function as solubilizing agents.

Gilberg L, Zhang B, Zavalij PY, Sindelar V, Isaacs L.

Org Biomol Chem. 2015 Apr 7;13(13):4041-50. doi: 10.1039/c5ob00184f.

37.

Hydrophobic monofunctionalized cucurbit[7]uril undergoes self-inclusion complexation and forms vesicle-type assemblies.

Yu Y, Li J, Zhang M, Cao L, Isaacs L.

Chem Commun (Camb). 2015 Mar 4;51(18):3762-5. doi: 10.1039/c5cc00236b.

PMID:
25647163
38.

Mesoporous Silica Nanoparticles Coated by Layer-by-Layer Self-assembly Using Cucurbit[7]uril for in Vitro and in Vivo Anticancer Drug Release.

Li QL, Sun Y, Sun YL, Wen J, Zhou Y, Bing QM, Isaacs LD, Jin Y, Gao H, Yang YW.

Chem Mater. 2014 Nov 25;26(22):6418-6431. Epub 2014 Oct 20.

39.

Photoinduced guest transformation promotes translocation of guest from hydroxypropyl-β-cyclodextrin to cucurbit[7]uril.

Fedorov YV, Tkachenko SV, Chernikova EY, Godovikov IA, Fedorova OA, Isaacs L.

Chem Commun (Camb). 2015 Jan 25;51(7):1349-52. doi: 10.1039/c4cc08474h.

PMID:
25485982
40.

The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles.

Oun R, Floriano RS, Isaacs L, Rowan EG, Wheate NJ.

Toxicol Res (Camb). 2014 Nov 1;3(6):447-455.

41.
42.
43.

Guest editorial: responsive host-guest systems.

Huang F, Isaacs L.

Acc Chem Res. 2014 Jul 15;47(7):1923-4. doi: 10.1021/ar500212y. No abstract available.

PMID:
25022546
44.

New small-molecule inhibitors effectively blocking picornavirus replication.

Ford Siltz LA, Viktorova EG, Zhang B, Kouiavskaia D, Dragunsky E, Chumakov K, Isaacs L, Belov GA.

J Virol. 2014 Oct;88(19):11091-107. doi: 10.1128/JVI.01877-14. Epub 2014 Jul 9.

45.

2,5-Dioxopyrrolidin-1-yl 2-methyl-prop-2-enoate.

Pearson WH, Lin S, Isaacs L.

Acta Crystallogr Sect E Struct Rep Online. 2014 Mar 15;70(Pt 4):o446. doi: 10.1107/S1600536814005170. eCollection 2014 Apr 1.

46.

Stimuli responsive systems constructed using cucurbit[n]uril-type molecular containers.

Isaacs L.

Acc Chem Res. 2014 Jul 15;47(7):2052-62. doi: 10.1021/ar500075g. Epub 2014 May 2.

47.

Acyclic CB[n]-type molecular containers: effect of solubilizing group on their function as solubilizing excipients.

Zhang B, Zavalij PY, Isaacs L.

Org Biomol Chem. 2014 Apr 21;12(15):2413-22. doi: 10.1039/c3ob42603c.

48.

Cucurbit[7]uril⋅guest pair with an attomolar dissociation constant.

Cao L, Śekutor M, Zavalij PY, Mlinarić-Majerski K, Glaser R, Isaacs L.

Angew Chem Int Ed Engl. 2014 Jan 20;53(4):988-93. doi: 10.1002/anie.201309635. Epub 2014 Jan 2.

PMID:
24382654
49.

"Turn-on" fluorescent sensor array for basic amino acids in water.

Minami T, Esipenko NA, Zhang B, Isaacs L, Anzenbacher P Jr.

Chem Commun (Camb). 2014 Jan 4;50(1):61-3. doi: 10.1039/c3cc47416j. Epub 2013 Nov 6.

PMID:
24196424
50.

Cucurbit[7]uril containers for targeted delivery of oxaliplatin to cancer cells.

Cao L, Hettiarachchi G, Briken V, Isaacs L.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12033-7. doi: 10.1002/anie.201305061. Epub 2013 Sep 13. No abstract available.

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