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A Positive Feedback Loop of Hippo- and c-Jun-Amino-Terminal Kinase Signaling Pathways Regulates Amyloid-Beta-Mediated Neurodegeneration.

Irwin M, Tare M, Singh A, Puli OR, Gogia N, Riccetti M, Deshpande P, Kango-Singh M, Singh A.

Front Cell Dev Biol. 2020 Mar 13;8:117. doi: 10.3389/fcell.2020.00117. eCollection 2020.


A new stiletto fly genus from South America (Diptera: Therevidae: Agapophytinae).

Irwin ME, Winterton SL.

Zootaxa. 2020 Mar 17;4751(2):zootaxa.4751.2.4. doi: 10.11646/zootaxa.4751.2.4.


A new stiletto fly in the genus Anabarhynchus Macquart (Diptera: Therevidae)from Fiji.

Irwin ME, Winterton SL.

Zootaxa. 2019 Nov 20;4700(3):zootaxa.4700.3.7. doi: 10.11646/zootaxa.4700.3.7.


Environmental Enrichment in Postoperative Pain and Surgical Care: Potential Synergism With the Enhanced Recovery After Surgery Pathway.

Yeung SC, Irwin MG, Cheung CW.

Ann Surg. 2020 Mar 20. doi: 10.1097/SLA.0000000000003878. [Epub ahead of print]


Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection.

Ford BN, Teague TK, Bayouth M, Yolken RH, Bodurka J, Irwin MR, Paulus MP, Savitz J.

Brain Behav Immun. 2020 Mar 21. pii: S0889-1591(19)31335-2. doi: 10.1016/j.bbi.2020.03.013. [Epub ahead of print]


Implications of abnormal abdominal wall computed tomographic angiography findings on postmastectomy free flap breast reconstruction.

Ngaage LM, Hamed RR, Oni G, Ghorra DT, Ang JZ, Koo BC, Benyon SL, Irwin MS, Malata CM.

Arch Plast Surg. 2020 Mar;47(2):146-152. doi: 10.5999/aps.2019.00801. Epub 2020 Mar 15.


Adiponectin Facilitates Postconditioning Cardioprotection through Both AMPK-Dependent Nuclear and AMPK-Independent Mitochondrial STAT3 Activation.

Zhu Q, Li H, Xie X, Chen X, Kosuru R, Li S, Lian Q, Cheung CW, Irwin MG, Ge RS, Xia Z.

Oxid Med Cell Longev. 2020 Mar 4;2020:4253457. doi: 10.1155/2020/4253457. eCollection 2020.


Sleep Disruption Due to Stress in Women Veterans: A Comparison between Caregivers and Noncaregivers.

Song Y, Carlson GC, McGowan SK, Fung CH, Josephson KR, Mitchell MN, McCurry SM, Teng E, Irwin MR, Alessi CA, Martin JL.

Behav Sleep Med. 2020 Feb 29:1-12. doi: 10.1080/15402002.2020.1732981. [Epub ahead of print]


Randomized Phase II Trial of Exercise, Metformin, or Both on Metabolic Biomarkers in Colorectal and Breast Cancer Survivors.

Meyerhardt JA, Irwin ML, Jones LW, Zhang S, Campbell N, Brown JC, Pollak M, Sorrentino A, Cartmel B, Harrigan M, Tolaney SM, Winer E, Ng K, Abrams T, Fuchs CS, Sanft T, Douglas PS, Hu F, Ligibel JA.

JNCI Cancer Spectr. 2019 Nov 20;4(1):pkz096. doi: 10.1093/jncics/pkz096. eCollection 2020 Feb.


Transdisciplinary Research in Energetics and Cancer early career investigator training program: first year results.

Irwin ML, Lowry D, Neuhouser ML, Ligibel J, Schmitz K, Patterson RE, Colditz G, Li F, Nebeling L.

Transl Behav Med. 2020 Feb 17. pii: ibaa009. doi: 10.1093/tbm/ibaa009. [Epub ahead of print]


Generativity and Social Well-Being in Older Women: Expectations Regarding Aging Matter.

Moieni M, Seeman TE, Robles TF, Lieberman MD, Okimoto S, Lengacher C, Irwin MR, Eisenberger NI.

J Gerontol B Psychol Sci Soc Sci. 2020 Feb 17. pii: gbaa022. doi: 10.1093/geronb/gbaa022. [Epub ahead of print]


Risk factors for hepatocellular carcinoma (HCC) in the northeast of the United States: results of a case-control study.

Shen Y, Risch H, Lu L, Ma X, Irwin ML, Lim JK, Taddei T, Pawlish K, Stroup A, Brown R, Wang Z, Jia W, Wong L, Mayne ST, Yu H.

Cancer Causes Control. 2020 Apr;31(4):321-332. doi: 10.1007/s10552-020-01277-1. Epub 2020 Feb 14.


Changes in inflammation are related to depression and amount of aerobic exercise in first episode schizophrenia.

Ventura J, McEwen S, Subotnik KL, Hellemann GS, Ghadiali M, Rahimdel A, Seo MJ, Irwin MR, Nuechterlein KH.

Early Interv Psychiatry. 2020 Feb 13. doi: 10.1111/eip.12946. [Epub ahead of print]


Anesthetic Management for Squamous Cell Carcinoma of the Esophagus.

Chan EYF, Ip DKY, Irwin MG.

Methods Mol Biol. 2020;2129:359-383. doi: 10.1007/978-1-0716-0377-2_26.


Deletion of Rap1 protects against myocardial ischemia/reperfusion injury through suppressing cell apoptosis via activation of STAT3 signaling.

Cai Y, Ying F, Liu H, Ge L, Song E, Wang L, Zhang D, Hoi Ching Tang E, Xia Z, Irwin MG.

FASEB J. 2020 Mar;34(3):4482-4496. doi: 10.1096/fj.201901592RR. Epub 2020 Feb 5.


Incidence and prognostic role of the ocular manifestations of neuroblastoma in children.

Graef S, Irwin MS, Wan MJ.

Am J Ophthalmol. 2020 Jan 29. pii: S0002-9394(20)30032-5. doi: 10.1016/j.ajo.2020.01.023. [Epub ahead of print]


Influence of propofol-based total intravenous anaesthesia on peri-operative outcome measures: a narrative review.

Irwin MG, Chung CKE, Ip KY, Wiles MD.

Anaesthesia. 2020 Jan;75 Suppl 1:e90-e100. doi: 10.1111/anae.14905. Review.


Allopurinol reduces oxidative stress and activates Nrf2/p62 to attenuate diabetic cardiomyopathy in rats.

Luo J, Yan D, Li S, Liu S, Zeng F, Cheung CW, Liu H, Irwin MG, Huang H, Xia Z.

J Cell Mol Med. 2020 Jan;24(2):1760-1773. doi: 10.1111/jcmm.14870. Epub 2019 Dec 19.


Regulatory oversight for research tests and laboratory-developed diagnostics should be more nimble.

Berry DM, Parekh RS, Irwin MS.

CMAJ. 2019 Dec 16;191(50):E1388. doi: 10.1503/cmaj.73818. No abstract available.


An international multidisciplinary consensus statement on fasting before procedural sedation in adults and children.

Green SM, Leroy PL, Roback MG, Irwin MG, Andolfatto G, Babl FE, Barbi E, Costa LR, Absalom A, Carlson DW, Krauss BS, Roelofse J, Yuen VM, Alcaino E, Costa PS, Mason KP; International Committee for the Advancement of Procedural Sedation.

Anaesthesia. 2020 Mar;75(3):374-385. doi: 10.1111/anae.14892. Epub 2019 Dec 2. Review.


Feeling needed: Effects of a randomized generativity intervention on well-being and inflammation in older women.

Moieni M, Irwin MR, Seeman TE, Robles TF, Lieberman MD, Breen EC, Okimoto S, Lengacher C, Arevalo JMG, Olmstead R, Cole SW, Eisenberger NI.

Brain Behav Immun. 2020 Feb;84:97-105. doi: 10.1016/j.bbi.2019.11.014. Epub 2019 Nov 20.


Sleep disturbance at pre-deployment is a significant predictor of post-deployment re-experiencing symptoms.

Acheson DT, Kwan B, Maihofer AX, Risbrough VB, Nievergelt CM, Clark JW, Tu XM, Irwin MR, Baker DG.

Eur J Psychotraumatol. 2019 Oct 29;10(1):1679964. doi: 10.1080/20008198.2019.1679964. eCollection 2019.


Exploring Social Dominance in Wild Diademed Sifakas (Propithecus diadema): Females Are Dominant, but It Is Subtle and the Benefits Are Not Clear.

Rasolonjatovo SM, Irwin MT.

Folia Primatol (Basel). 2019 Nov 6:1-14. doi: 10.1159/000503345. [Epub ahead of print]


The molecular architecture of photoreceptor phosphodiesterase 6 (PDE6) with activated G protein elucidates the mechanism of visual excitation.

Irwin MJ, Gupta R, Gao XZ, Cahill KB, Chu F, Cote RH.

J Biol Chem. 2019 Dec 20;294(51):19486-19497. doi: 10.1074/jbc.RA119.011002. Epub 2019 Nov 5.


Development of a dyadic sleep intervention for Alzheimer's disease patients and their caregivers.

Song Y, McCurry SM, Lee D, Josephson KR, McGowan SK, Fung CH, Irwin MR, Teng E, Alessi CA, Martin JL.

Disabil Rehabil. 2019 Oct 26:1-11. doi: 10.1080/09638288.2019.1680748. [Epub ahead of print]


Biobehavioral effects of Tai Chi Qigong in men with prostate cancer: Study design of a three-arm randomized clinical trial.

Kinney AY, Blair CK, Guest DD, Ani JK, Harding EM, Amorim F, Boyce T, Rodman J, Ford CG, Schwartz M, Rosenberg L, Foran O, Gardner J, Lin Y, Arap W, Irwin MR.

Contemp Clin Trials Commun. 2019 Aug 21;16:100431. doi: 10.1016/j.conctc.2019.100431. eCollection 2019 Dec.


Inflammation and Risk of Depression in HIV: Prospective Findings From the Multicenter AIDS Cohort Study.

Lu H, Surkan PJ, Irwin MR, Treisman GJ, Breen EC, Sacktor N, Stall R, Wolinsky SM, Jacobson LP, Abraham AG.

Am J Epidemiol. 2019 Nov 1;188(11):1994-2003. doi: 10.1093/aje/kwz190.


Sex Differences in the Effect of Inflammation on Subjective Social Status: A Randomized Controlled Trial of Endotoxin in Healthy Young Adults.

Moieni M, Muscatell KA, Jevtic I, Breen EC, Irwin MR, Eisenberger NI.

Front Psychol. 2019 Oct 1;10:2167. doi: 10.3389/fpsyg.2019.02167. eCollection 2019.


Individual differences in pain sensitivity are associated with cognitive network functional connectivity following one night of experimental sleep disruption.

Letzen JE, Remeniuk B, Smith MT, Irwin MR, Finan PH, Seminowicz DA.

Hum Brain Mapp. 2020 Feb 15;41(3):581-593. doi: 10.1002/hbm.24824. Epub 2019 Oct 16.


The ganglioside GD2 as a circulating tumor biomarker for neuroblastoma.

Balis FM, Busch CM, Desai AV, Hibbitts E, Naranjo A, Bagatell R, Irwin M, Fox E.

Pediatr Blood Cancer. 2020 Jan;67(1):e28031. doi: 10.1002/pbc.28031. Epub 2019 Oct 14.


The Role of Surgery in High-risk Neuroblastoma.

Ryan AL, Akinkuotu A, Pierro A, Morgenstern DA, Irwin MS.

J Pediatr Hematol Oncol. 2020 Jan;42(1):1-7. doi: 10.1097/MPH.0000000000001607.


Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling.

Lei S, Su W, Xia ZY, Wang Y, Zhou L, Qiao S, Zhao B, Xia Z, Irwin MG.

Oxid Med Cell Longev. 2019 Sep 5;2019:9836302. doi: 10.1155/2019/9836302. eCollection 2019.


Two major accretion epochs in M31 from two distinct populations of globular clusters.

Mackey D, Lewis GF, Brewer BJ, Ferguson AMN, Veljanoski J, Huxor AP, Collins MLM, Côté P, Ibata RA, Irwin MJ, Martin N, McConnachie AW, Peñarrubia J, Tanvir N, Wan Z.

Nature. 2019 Oct;574(7776):69-71. doi: 10.1038/s41586-019-1597-1. Epub 2019 Oct 2.


Integrative Approaches for Sleep Health in Cancer Survivors.

Garland SN, Mahon K, Irwin MR.

Cancer J. 2019 Sep/Oct;25(5):337-342. doi: 10.1097/PPO.0000000000000398.


Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas.

Guerreiro Stucklin AS, Ryall S, Fukuoka K, Zapotocky M, Lassaletta A, Li C, Bridge T, Kim B, Arnoldo A, Kowalski PE, Zhong Y, Johnson M, Li C, Ramani AK, Siddaway R, Nobre LF, de Antonellis P, Dunham C, Cheng S, Boué DR, Finlay JL, Coven SL, de Prada I, Perez-Somarriba M, Faria CC, Grotzer MA, Rushing E, Sumerauer D, Zamecnik J, Krskova L, Garcia Ariza M, Cruz O, Morales La Madrid A, Solano P, Terashima K, Nakano Y, Ichimura K, Nagane M, Sakamoto H, Gil-da-Costa MJ, Silva R, Johnston DL, Michaud J, Wilson B, van Landeghem FKH, Oviedo A, McNeely PD, Crooks B, Fried I, Zhukova N, Hansford JR, Nageswararao A, Garzia L, Shago M, Brudno M, Irwin MS, Bartels U, Ramaswamy V, Bouffet E, Taylor MD, Tabori U, Hawkins C.

Nat Commun. 2019 Sep 25;10(1):4343. doi: 10.1038/s41467-019-12187-5.


Circulating versus lipopolysaccharide-induced inflammatory markers as correlates of subthreshold depressive symptoms in older adults.

Lee SM, Te S, Breen EC, Olmstead R, Irwin MR, Cho JH.

World J Biol Psychiatry. 2019 Oct 9:1-8. doi: 10.1080/15622975.2019.1671608. [Epub ahead of print]


Novel neuroimmunologic therapeutics in depression: A clinical perspective on what we know so far.

Roman M, Irwin MR.

Brain Behav Immun. 2020 Jan;83:7-21. doi: 10.1016/j.bbi.2019.09.016. Epub 2019 Sep 21. Review.


Peri-operative considerations for sedation-analgesia during cataract surgery: a narrative review.

Kumar CM, Seet E, Eke T, Irwin MG, Joshi GP.

Anaesthesia. 2019 Dec;74(12):1601-1610. doi: 10.1111/anae.14845. Epub 2019 Sep 19. Review.


Moderators of Exercise Effects on Cancer-related Fatigue: A Meta-analysis of Individual Patient Data.

VAN Vulpen JK, Sweegers MG, Peeters PHM, Courneya KS, Newton RU, Aaronson NK, Jacobsen PB, Galvão DA, Chinapaw MJ, Steindorf K, Irwin ML, Stuiver MM, Hayes S, Griffith KA, Mesters I, Knoop H, Goedendorp MM, Mutrie N, Daley AJ, McConnachie A, Bohus M, Thorsen L, Schulz KH, Short CE, James EL, Plotnikoff RC, Schmidt ME, Ulrich CM, VAN Beurden M, Oldenburg HS, Sonke GS, VAN Harten WH, Schmitz KH, Winters-Stone KM, Velthuis MJ, Taaffe DR, VAN Mechelen W, Kersten MJ, Nollet F, Wenzel J, Wiskemann J, Verdonck-DE Leeuw IM, Brug J, May AM, Buffart LM.

Med Sci Sports Exerc. 2020 Feb;52(2):303-314. doi: 10.1249/MSS.0000000000002154.


Corrigendum to "Experienced discrimination and racial differences in leukocyte gene expression. [Psychoneuroendocrinology, 106 (2019), 277-283]".

Thames AD, Irwin MR, Breen EC, Cole SW.

Psychoneuroendocrinology. 2019 Nov;109:104422. doi: 10.1016/j.psyneuen.2019.104422. Epub 2019 Sep 10. No abstract available.


Anaesthetic considerations in nonagenarians and centenarians.

Irwin MG, Ip KY, Hui YM.

Curr Opin Anaesthesiol. 2019 Dec;32(6):776-782. doi: 10.1097/ACO.0000000000000793. Review.


Tandem Transplant for High-Risk Neuroblastoma: Next Steps in the Era of Precision Medicine.

Bagatell R, Irwin MS.

JAMA. 2019 Aug 27;322(8):729-731. doi: 10.1001/jama.2019.11641. No abstract available.


Persistent Low Positive Affect and Sleep Disturbance across Adolescence Moderate Link between Stress and Depressive Symptoms in Early Adulthood.

Kuhlman KR, Chiang JJ, Bower JE, Irwin MR, Cole SW, Dahl RE, Almeida DM, Fuligni AJ.

J Abnorm Child Psychol. 2020 Jan;48(1):109-121. doi: 10.1007/s10802-019-00581-y.


Intense interseasonal influenza outbreaks, Australia, 2018/19.

Barr IG, Deng YM, Grau ML, Han AX, Gilmour R, Irwin M, Markey P, Freeman K, Higgins G, Turra M, Komadina N, Peck H, Booy R, Maurer-Stroh S, Dhanasekaran V, Sullivan S.

Euro Surveill. 2019 Aug;24(33). doi: 10.2807/1560-7917.ES.2019.24.33.1900421. Erratum in: Euro Surveill. 2019 Aug;24(34):.


Sleep problems in adolescence are prospectively linked to later depressive symptoms via the cortisol awakening response.

Kuhlman KR, Chiang JJ, Bower JE, Irwin MR, Seeman TE, McCreath HE, Almeida DM, Dahl RE, Fuligni AJ.

Dev Psychopathol. 2019 Aug 7:1-10. doi: 10.1017/S0954579419000762. [Epub ahead of print]


Kynurenine metabolism and inflammation-induced depressed mood: A human experimental study.

Kruse JL, Cho JH, Olmstead R, Hwang L, Faull K, Eisenberger NI, Irwin MR.

Psychoneuroendocrinology. 2019 Nov;109:104371. doi: 10.1016/j.psyneuen.2019.104371. Epub 2019 Jul 3.


Sleep and inflammation: partners in sickness and in health.

Irwin MR.

Nat Rev Immunol. 2019 Nov;19(11):702-715. doi: 10.1038/s41577-019-0190-z. Review.


Global phylogeography and ancient evolution of the widespread human gut virus crAssphage.

Edwards RA, Vega AA, Norman HM, Ohaeri M, Levi K, Dinsdale EA, Cinek O, Aziz RK, McNair K, Barr JJ, Bibby K, Brouns SJJ, Cazares A, de Jonge PA, Desnues C, Díaz Muñoz SL, Fineran PC, Kurilshikov A, Lavigne R, Mazankova K, McCarthy DT, Nobrega FL, Reyes Muñoz A, Tapia G, Trefault N, Tyakht AV, Vinuesa P, Wagemans J, Zhernakova A, Aarestrup FM, Ahmadov G, Alassaf A, Anton J, Asangba A, Billings EK, Cantu VA, Carlton JM, Cazares D, Cho GS, Condeff T, Cortés P, Cranfield M, Cuevas DA, De la Iglesia R, Decewicz P, Doane MP, Dominy NJ, Dziewit L, Elwasila BM, Eren AM, Franz C, Fu J, Garcia-Aljaro C, Ghedin E, Gulino KM, Haggerty JM, Head SR, Hendriksen RS, Hill C, Hyöty H, Ilina EN, Irwin MT, Jeffries TC, Jofre J, Junge RE, Kelley ST, Khan Mirzaei M, Kowalewski M, Kumaresan D, Leigh SR, Lipson D, Lisitsyna ES, Llagostera M, Maritz JM, Marr LC, McCann A, Molshanski-Mor S, Monteiro S, Moreira-Grez B, Morris M, Mugisha L, Muniesa M, Neve H, Nguyen NP, Nigro OD, Nilsson AS, O'Connell T, Odeh R, Oliver A, Piuri M, Prussin Ii AJ, Qimron U, Quan ZX, Rainetova P, Ramírez-Rojas A, Raya R, Reasor K, Rice GAO, Rossi A, Santos R, Shimashita J, Stachler EN, Stene LC, Strain R, Stumpf R, Torres PJ, Twaddle A, Ugochi Ibekwe M, Villagra N, Wandro S, White B, Whiteley A, Whiteson KL, Wijmenga C, Zambrano MM, Zschach H, Dutilh BE.

Nat Microbiol. 2019 Oct;4(10):1727-1736. doi: 10.1038/s41564-019-0494-6. Epub 2019 Jul 8.


Mindfulness meditation and improvement in depressive symptoms among Spanish- and English speaking adults: A randomized, controlled, comparative efficacy trial.

Lopez-Maya E, Olmstead R, Irwin MR.

PLoS One. 2019 Jul 5;14(7):e0219425. doi: 10.1371/journal.pone.0219425. eCollection 2019.


Morphometric signals of population decline in diademed sifakas occupying degraded rainforest habitat in Madagascar.

Irwin MT, Samonds KE, Raharison JL, Junge RE, Mahefarisoa KL, Rasambainarivo F, Godfrey LR, Glander KE.

Sci Rep. 2019 Jun 19;9(1):8776. doi: 10.1038/s41598-019-45426-2.

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