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Items: 1 to 50 of 162


Genome wide analyses uncover allele-specific RNA editing in human and mouse.

Zhou ZY, Hu Y, Li A, Li YJ, Zhao H, Wang SQ, Otecko NO, Zhang D, Wang JH, Liu Y, Irwin DM, Qin Y, Zhang YP.

Nucleic Acids Res. 2018 Jul 12. doi: 10.1093/nar/gky613. [Epub ahead of print]


Evolutionary dynamics of avian influenza A H7N9 virus across five waves in mainland China, 2013-2017.

Xiang D, Pu Z, Luo T, Guo F, Li X, Shen X, Irwin DM, Murphy RW, Liao M, Shen Y.

J Infect. 2018 May 25. pii: S0163-4453(18)30158-0. doi: 10.1016/j.jinf.2018.05.006. [Epub ahead of print]


Evolution of Trichocyte Keratin Associated Proteins.

Wu DD, Irwin DM.

Adv Exp Med Biol. 2018;1054:47-56. doi: 10.1007/978-981-10-8195-8_5.


Diversification of the functions of proglucagon and glucagon receptor genes in fish.

Irwin DM, Mojsov S.

Gen Comp Endocrinol. 2018 May 15;261:148-165. doi: 10.1016/j.ygcen.2018.03.003. Epub 2018 Mar 3.


Convergent Evolution of Human-Isolated H7N9 Avian Influenza A Viruses.

Xiang D, Shen X, Pu Z, Irwin DM, Liao M, Shen Y.

J Infect Dis. 2018 May 5;217(11):1699-1707. doi: 10.1093/infdis/jiy082.


The genetic and phylogenetic analysis of a highly pathogenic influenza A H5N6 virus from a heron, southern China, 2013.

Luo K, Zhang K, Liu L, Shen X, Jiao P, Song Y, Lv J, Wang M, Liu Y, Qi W, Ren T, Irwin DM, Liao M, Shen Y.

Infect Genet Evol. 2018 Apr;59:72-74. doi: 10.1016/j.meegid.2018.01.028. Epub 2018 Jan 31.


Excessive Autophagy Activation and Increased Apoptosis Are Associated with Palmitic Acid-Induced Cardiomyocyte Insulin Resistance.

Li S, Li H, Yang D, Yu X, Irwin DM, Niu G, Tan H.

J Diabetes Res. 2017;2017:2376893. doi: 10.1155/2017/2376893. Epub 2017 Nov 26.


PigVar: a database of pig variations and positive selection signatures.

Zhou ZY, Li A, Otecko NO, Liu YH, Irwin DM, Wang L, Adeola AC, Zhang J, Xie HB, Zhang YP.

Database (Oxford). 2017 Jan 1;2017. doi: 10.1093/database/bax048.


The H7N9 viruses have lost most of their previous lineages in the fifth wave.

Xiang D, Irwin DM, Shen Y.

J Infect. 2018 Apr;76(4):417-418. doi: 10.1016/j.jinf.2017.11.007. Epub 2017 Dec 1. No abstract available.


Tumacrophage: macrophages transformed into tumor stem-like cells by virulent genetic material from tumor cells.

Zhang Y, Zhou N, Yu X, Zhang X, Li S, Lei Z, Hu R, Li H, Mao Y, Wang X, Zhang J, Li Y, Guo H, Irwin DM, Niu G, Tan H.

Oncotarget. 2017 Jul 18;8(47):82326-82343. doi: 10.18632/oncotarget.19320. eCollection 2017 Oct 10.


Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing.

Zeng L, Ming C, Li Y, Su LY, Su YH, Otecko NO, Dalecky A, Donnellan S, Aplin K, Liu XH, Song Y, Zhang ZB, Esmailizadeh A, Sohrabi SS, Nanaei HA, Liu HQ, Wang MS, Ag Atteynine S, Rocamora G, Brescia F, Morand S, Irwin DM, Peng MS, Yao YG, Li HP, Wu DD, Zhang YP.

Mol Biol Evol. 2018 Jan 1;35(1):149-158. doi: 10.1093/molbev/msx276.


Comparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis.

Song R, Chen L, Chen Y, Si X, Liu Y, Liu Y, Irwin DM, Feng W.

PLoS One. 2017 Aug 3;12(8):e0182488. doi: 10.1371/journal.pone.0182488. eCollection 2017.


Evolution of the vertebrate insulin receptor substrate (Irs) gene family.

Al-Salam A, Irwin DM.

BMC Evol Biol. 2017 Jun 23;17(1):148. doi: 10.1186/s12862-017-0994-z.


Highly pathogenic H5N6 influenza A viruses recovered from wild birds in Guangdong, southern China, 2014-2015.

Kang Y, Liu L, Feng M, Yuan R, Huang C, Tan Y, Gao P, Xiang D, Zhao X, Li Y, Irwin DM, Shen Y, Ren T.

Sci Rep. 2017 Mar 15;7:44410. doi: 10.1038/srep44410.


The origin of chow chows in the light of the East Asian breeds.

Yang H, Wang G, Wang M, Ma Y, Yin T, Fan R, Wu H, Zhong L, Irwin DM, Zhai W, Zhang Y.

BMC Genomics. 2017 Feb 16;18(1):174. doi: 10.1186/s12864-017-3525-9.


Comparative population genomics reveals genetic basis underlying body size of domestic chickens.

Wang MS, Huo YX, Li Y, Otecko NO, Su LY, Xu HB, Wu SF, Peng MS, Liu HQ, Zeng L, Irwin DM, Yao YG, Wu DD, Zhang YP.

J Mol Cell Biol. 2016 Dec;8(6):542-552. Epub 2016 Oct 15.


Xinmailong mitigated epirubicin-induced cardiotoxicity via inhibiting autophagy.

Li H, Mao Y, Zhang Q, Han Q, Man Z, Zhang J, Wang X, Hu R, Zhang X, Irwin DM, Niu G, Tan H.

J Ethnopharmacol. 2016 Nov 4;192:459-470. doi: 10.1016/j.jep.2016.08.031. Epub 2016 Aug 30.


Bats: Body mass index, forearm mass index, blood glucose levels and SLC2A2 genes for diabetes.

Meng F, Zhu L, Huang W, Irwin DM, Zhang S.

Sci Rep. 2016 Jul 21;6:29960. doi: 10.1038/srep29960.


Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation.

Yu L, Wang GD, Ruan J, Chen YB, Yang CP, Cao X, Wu H, Liu YH, Du ZL, Wang XP, Yang J, Cheng SC, Zhong L, Wang L, Wang X, Hu JY, Fang L, Bai B, Wang KL, Yuan N, Wu SF, Li BG, Zhang JG, Yang YQ, Zhang CL, Long YC, Li HS, Yang JY, Irwin DM, Ryder OA, Li Y, Wu CI, Zhang YP.

Nat Genet. 2016 Aug;48(8):947-52. doi: 10.1038/ng.3615. Epub 2016 Jul 11.


Multiple specialised goose-type lysozymes potentially compensate for an exceptional lack of chicken-type lysozymes in Atlantic cod.

Seppola M, Bakkemo KR, Mikkelsen H, Myrnes B, Helland R, Irwin DM, Nilsen IW.

Sci Rep. 2016 Jun 21;6:28318. doi: 10.1038/srep28318.


Genetic variations associated with six-white-point coat pigmentation in Diannan small-ear pigs.

Lü MD, Han XM, Ma YF, Irwin DM, Gao Y, Deng JK, Adeola AC, Xie HB, Zhang YP.

Sci Rep. 2016 Jun 8;6:27534. doi: 10.1038/srep27534.


Prolonged treatment with 3-isobutyl-1-methylxanthine improves the efficiency of differentiating 3T3-L1 cells into adipocytes.

Hua Y, Ke S, Wang Y, Irwin DM, Zhang S, Wang Z.

Anal Biochem. 2016 Aug 15;507:18-20. doi: 10.1016/j.ab.2016.05.007. Epub 2016 May 19.


Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication.

Wang MS, Zhang RW, Su LY, Li Y, Peng MS, Liu HQ, Zeng L, Irwin DM, Du JL, Yao YG, Wu DD, Zhang YP.

Cell Res. 2016 May;26(5):556-73. doi: 10.1038/cr.2016.44. Epub 2016 Apr 1.


Host genetics is associated with the gut microbial community membership rather than the structure.

Zhao P, Irwin DM, Dong D.

Mol Biosyst. 2016 Apr 26;12(5):1676-86. doi: 10.1039/c5mb00850f.


Identification of HNF4A Mutation p.T130I and HNF1A Mutations p.I27L and p.S487N in a Han Chinese Family with Early-Onset Maternally Inherited Type 2 Diabetes.

Yang Y, Zhou TC, Liu YY, Li X, Wang WX, Irwin DM, Zhang YP.

J Diabetes Res. 2016;2016:3582616. doi: 10.1155/2016/3582616. Epub 2016 Feb 11.


Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.

Singh P, Irwin DM.

PLoS One. 2016 Feb 24;11(2):e0149682. doi: 10.1371/journal.pone.0149682. eCollection 2016.


Repetitive transpositions of mitochondrial DNA sequences to the nucleus during the radiation of horseshoe bats (Rhinolophus, Chiroptera).

Shi H, Dong J, Irwin DM, Zhang S, Mao X.

Gene. 2016 May 1;581(2):161-9. doi: 10.1016/j.gene.2016.01.035. Epub 2016 Jan 22.


Molecular Evolution of the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene Nrf2 in Old World Fruit Bats (Chiroptera: Pteropodidae).

Yin Q, Zhu L, Liu D, Irwin DM, Zhang S, Pan YH.

PLoS One. 2016 Jan 6;11(1):e0146274. doi: 10.1371/journal.pone.0146274. eCollection 2016.


Out of southern East Asia: the natural history of domestic dogs across the world.

Wang GD, Zhai W, Yang HC, Wang L, Zhong L, Liu YH, Fan RX, Yin TT, Zhu CL, Poyarkov AD, Irwin DM, Hytönen MK, Lohi H, Wu CI, Savolainen P, Zhang YP.

Cell Res. 2016 Jan;26(1):21-33. doi: 10.1038/cr.2015.147. Epub 2015 Dec 15.


Population Variation Reveals Independent Selection toward Small Body Size in Chinese Debao Pony.

Kader A, Li Y, Dong K, Irwin DM, Zhao Q, He X, Liu J, Pu Y, Gorkhali NA, Liu X, Jiang L, Li X, Guan W, Zhang Y, Wu DD, Ma Y.

Genome Biol Evol. 2015 Dec 3;8(1):42-50. doi: 10.1093/gbe/evv245.


Genetic adaptations of the plateau zokor in high-elevation burrows.

Shao Y, Li JX, Ge RL, Zhong L, Irwin DM, Murphy RW, Zhang YP.

Sci Rep. 2015 Nov 25;5:17262. doi: 10.1038/srep17262.


DNA methylation signatures of long intergenic noncoding RNAs in porcine adipose and muscle tissues.

Zhou ZY, Li A, Wang LG, Irwin DM, Liu YH, Xu D, Han XM, Wang L, Wu SF, Wang LX, Xie HB, Zhang YP.

Sci Rep. 2015 Oct 23;5:15435. doi: 10.1038/srep15435.


Staurosporine Induced Apoptosis May Activate Cancer Stem-Like Cells (CD44(+)/CD24(-)) in MCF-7 by Upregulating Mucin1 and EpCAM.

Zhou N, Wang R, Zhang Y, Lei Z, Zhang X, Hu R, Li H, Mao Y, Wang X, Irwin DM, Niu G, Tan H.

J Cancer. 2015 Sep 1;6(10):1049-57. doi: 10.7150/jca.12501. eCollection 2015.


Integrative analyses of RNA editing, alternative splicing, and expression of young genes in human brain transcriptome by deep RNA sequencing.

Wu DD, Ye LQ, Li Y, Sun YB, Shao Y, Chen C, Zhu Z, Zhong L, Wang L, Irwin DM, Zhang YE, Zhang YP.

J Mol Cell Biol. 2015 Aug;7(4):314-25. doi: 10.1093/jmcb/mjv043. Epub 2015 Jul 17.


Evolution of the Vertebrate Resistin Gene Family.

Hu Q, Tan H, Irwin DM.

PLoS One. 2015 Jun 15;10(6):e0130188. doi: 10.1371/journal.pone.0130188. eCollection 2015.


Exposure of tumor-associated macrophages to apoptotic MCF-7 cells promotes breast cancer growth and metastasis.

Zhou N, Zhang Y, Zhang X, Lei Z, Hu R, Li H, Mao Y, Wang X, Irwin DM, Niu G, Tan H.

Int J Mol Sci. 2015 May 26;16(6):11966-82. doi: 10.3390/ijms160611966.


Role of glucokinase in the subcellular localization of glucokinase regulatory protein.

Jin L, Guo T, Li Z, Lei Z, Li H, Mao Y, Wang X, Zhou N, Zhang Y, Hu R, Zhang X, Niu G, Irwin DM, Tan H.

Int J Mol Sci. 2015 Apr 2;16(4):7377-93. doi: 10.3390/ijms16047377.


Phosphoenolpyruvate carboxykinase 1 gene (Pck1) displays parallel evolution between Old World and New World fruit bats.

Zhu L, Yin Q, Irwin DM, Zhang S.

PLoS One. 2015 Mar 25;10(3):e0118666. doi: 10.1371/journal.pone.0118666. eCollection 2015.


Genomic Analyses Reveal Potential Independent Adaptation to High Altitude in Tibetan Chickens.

Wang MS, Li Y, Peng MS, Zhong L, Wang ZJ, Li QY, Tu XL, Dong Y, Zhu CL, Wang L, Yang MM, Wu SF, Miao YW, Liu JP, Irwin DM, Wang W, Wu DD, Zhang YP.

Mol Biol Evol. 2015 Jul;32(7):1880-9. doi: 10.1093/molbev/msv071. Epub 2015 Mar 18.


Genomic organization and evolution of ruminant lysozyme c genes.

Irwin DM.

Dongwuxue Yanjiu. 2015 Jan 18;36(1):1-17. doi: 10.13918/j.issn.2095-8137.2015.1.1.


Genome-wide identification and characterization of teleost-specific microRNAs within zebrafish.

Yang L, Irwin DM, He S.

Gene. 2015 May 1;561(2):181-9. doi: 10.1016/j.gene.2015.02.055. Epub 2015 Feb 19.


Nocturnal to diurnal transition in the common ancestor of haplorrhines: evidence from genomic-scan for positively selected genes.

Cao X, Sun YB, Irwin DM, Wang GD, Zhang YP.

J Genet Genomics. 2015 Jan 20;42(1):33-7. doi: 10.1016/j.jgg.2014.11.004. Epub 2014 Nov 24. No abstract available.


Integrative analysis of young genes, positively selected genes and lncRNAs in the development of Drosophila melanogaster.

Liu HQ, Li Y, Irwin DM, Zhang YP, Wu DD.

BMC Evol Biol. 2014 Dec 4;14:241. doi: 10.1186/s12862-014-0241-9.


Complete mtDNA genomes reveal similar penetrances of maternally inherited type 2 diabetes in two Chinese families.

Yang Y, Zhou T, Peng M, Liu Y, Li Y, Wang H, Irwin DM, Zhang Y.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 May;27(3):2040-4. doi: 10.3109/19401736.2014.982552. Epub 2014 Dec 3.


DoGSD: the dog and wolf genome SNP database.

Bai B, Zhao WM, Tang BX, Wang YQ, Wang L, Zhang Z, Yang HC, Liu YH, Zhu JW, Irwin DM, Wang GD, Zhang YP.

Nucleic Acids Res. 2015 Jan;43(Database issue):D777-83. doi: 10.1093/nar/gku1174. Epub 2014 Nov 17.


The great roundleaf bat (Hipposideros armiger) as a good model for cold-induced browning of intra-abdominal white adipose tissue.

Wang Y, Zhu T, Ke S, Fang N, Irwin DM, Lei M, Zhang J, Shi H, Zhang S, Wang Z.

PLoS One. 2014 Nov 13;9(11):e112495. doi: 10.1371/journal.pone.0112495. eCollection 2014.


Domestication of the dog from the wolf was promoted by enhanced excitatory synaptic plasticity: a hypothesis.

Li Y, Wang GD, Wang MS, Irwin DM, Wu DD, Zhang YP.

Genome Biol Evol. 2014 Nov 5;6(11):3115-21. doi: 10.1093/gbe/evu245.


Balancing selection on CDH2 may be related to the behavioral features of the Belgian Malinois.

Cao X, Irwin DM, Liu YH, Cheng LG, Wang L, Wang GD, Zhang YP.

PLoS One. 2014 Oct 10;9(10):e110075. doi: 10.1371/journal.pone.0110075. eCollection 2014.


Introgression of mitochondrial DNA promoted by natural selection in the Japanese pipistrelle bat (Pipistrellus abramus).

Dong J, Mao X, Sun H, Irwin DM, Zhang S, Hua P.

Genetica. 2014 Dec;142(6):483-94. doi: 10.1007/s10709-014-9794-1. Epub 2014 Sep 30.


"Out of pollen" hypothesis for origin of new genes in flowering plants: study from Arabidopsis thaliana.

Wu DD, Wang X, Li Y, Zeng L, Irwin DM, Zhang YP.

Genome Biol Evol. 2014 Sep 17;6(10):2822-9. doi: 10.1093/gbe/evu206.

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