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Items: 16


High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.

Vaisar T, Kanter JE, Wimberger J, Irwin AD, Gauthier J, Wolfson E, Bahnam V, Wu IH, Shah H, Keenan HA, Greenbaum CJ, King GL, Heinecke JW, Bornfeldt KE.

Diabetes Care. 2019 Oct 9. pii: dc190772. doi: 10.2337/dc19-0772. [Epub ahead of print]


Revising Pediatric Vancomycin Dosing Accounting for Nephrotoxicity in a Pharmacokinetic-Pharmacodynamic Model.

Kloprogge F, Hill LF, Booth J, Klein N, Irwin AD, Dixon G, Standing JF.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00067-19. doi: 10.1128/AAC.00067-19. Print 2019 May.


Detection of Epidemic Scarlet Fever Group A Streptococcus in Australia.

Walker MJ, Brouwer S, Forde BM, Worthing KA, McIntyre L, Sundac L, Maloney S, Roberts LW, Barnett TC, Richter J, Cork AJ, Irwin AD, You Y, Zhang J, Dougan G, Yuen KY, Nizet V, Beatson SA, Grimwood K, Davies MR.

Clin Infect Dis. 2019 Sep 13;69(7):1232-1234. doi: 10.1093/cid/ciz099.


A case for reduced frequency of CD4 count monitoring for children on combination antiretroviral therapy with consistently undetectable HIV viral load.

Johnson SM, Standing JF, Klein N, Irwin AD, Shingadia D, Lonsdale DO, Gilmour KC, Flynn J, Manns C, Clapson M, Bamford A.

HIV Med. 2019 Apr;20(4):e8-e9. doi: 10.1111/hiv.12706. Epub 2019 Jan 28. No abstract available.


Question 2: Are three malaria tests necessary in children returning from the tropics with fever?

Wilson IE, Shingadia D, Yeung S, Riordan A, Irwin AD.

Arch Dis Child. 2018 Jan;103(1):1-3. doi: 10.1136/archdischild-2017-313843. Epub 2017 Oct 24. No abstract available.


Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department.

Irwin AD, Grant A, Williams R, Kolamunnage-Dona R, Drew RJ, Paulus S, Jeffers G, Williams K, Breen R, Preston J, Appelbe D, Chesters C, Newland P, Marzouk O, McNamara PS, Diggle PJ, Carrol ED.

Pediatrics. 2017 Aug;140(2). pii: e20162853. doi: 10.1542/peds.2016-2853. Epub 2017 Jul 5.


Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration.

Monette JS, Hutchins PM, Ronsein GE, Wimberger J, Irwin AD, Tang C, Sara JD, Shao B, Vaisar T, Lerman A, Heinecke JW.

Circ Res. 2016 Jun 24;119(1):83-90. doi: 10.1161/CIRCRESAHA.116.308357. Epub 2016 Apr 25.


Supporting decisions to increase the safe discharge of children with febrile illness from the emergency department: a systematic review and meta-analysis.

Irwin AD, Wickenden J, Le Doare K, Ladhani S, Sharland M.

Arch Dis Child. 2016 Mar;101(3):259-66. doi: 10.1136/archdischild-2015-309056. Epub 2015 Dec 30. Review.


Etiology of childhood bacteremia and timely antibiotics administration in the emergency department.

Irwin AD, Drew RJ, Marshall P, Nguyen K, Hoyle E, Macfarlane KA, Wong HF, Mekonnen E, Hicks M, Steele T, Gerrard C, Hardiman F, McNamara PS, Diggle PJ, Carrol ED.

Pediatrics. 2015 Apr;135(4):635-42. doi: 10.1542/peds.2014-2061. Epub 2015 Mar 9.


Commentaries on 'procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections' with a response from the review authors.

Sabhaney V, Enarson P, Irwin AD, Carrol ED.

Evid Based Child Health. 2013 Jul;8(4):1372-4. doi: 10.1002/ebch.1928.


Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children.

Irwin AD, Marriage F, Mankhambo LA; IPD Group Study, Jeffers G, Kolamunnage-Dona R, Guiver M, Denis B, Molyneux EM, Molyneux ME, Day PJ, Carrol ED.

BMC Med Genomics. 2012 May 4;5:13. doi: 10.1186/1755-8794-5-13.


Unique proteomic signatures distinguish macrophages and dendritic cells.

Becker L, Liu NC, Averill MM, Yuan W, Pamir N, Peng Y, Irwin AD, Fu X, Bornfeldt KE, Heinecke JW.

PLoS One. 2012;7(3):e33297. doi: 10.1371/journal.pone.0033297. Epub 2012 Mar 12.



Irwin AD, Carrol ED.

Arch Dis Child Educ Pract Ed. 2011 Dec;96(6):228-33. doi: 10.1136/archdischild-2011-300178. Epub 2011 Oct 12. Review. No abstract available.


A macrophage sterol-responsive network linked to atherogenesis.

Becker L, Gharib SA, Irwin AD, Wijsman E, Vaisar T, Oram JF, Heinecke JW.

Cell Metab. 2010 Feb 3;11(2):125-35. doi: 10.1016/j.cmet.2010.01.003.


p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules.

Hartson SD, Irwin AD, Shao J, Scroggins BT, Volk L, Huang W, Matts RL.

Biochemistry. 2000 Jun 27;39(25):7631-44.


Surgical antibiotic prophylaxis, patient morbidity, and cost reduction: a three-year study.

Scalley RD, Irwin AD, Poduska PJ, Wolff AJ, Cochran RS.

Drug Intell Clin Pharm. 1987 Jul-Aug;21(7-8):648-52.


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