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Items: 18


UV light suppression of EAE (a mouse model of multiple sclerosis) is independent of vitamin D and its receptor.

Irving AA, Marling SJ, Seeman J, Plum LA, DeLuca HF.

Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22552-22555. doi: 10.1073/pnas.1913294116. Epub 2019 Oct 21.


The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer.

Pleiman JK, Irving AA, Wang Z, Toraason E, Clipson L, Dove WF, Deming DA, Newton MA.

PLoS Genet. 2018 Sep 6;14(9):e1007611. doi: 10.1371/journal.pgen.1007611. eCollection 2018 Sep.


Vitamin D deficiency in the ApcPirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective.

Irving AA, Duchow EG, Plum LA, DeLuca HF.

Dis Model Mech. 2018 Mar 7;11(3). pii: dmm032300. doi: 10.1242/dmm.032300.


Suppression of experimental autoimmune encephalomyelitis by ultraviolet light is not mediated by isomerization of urocanic acid.

Irving AA, Marling SJ, Plum LA, DeLuca HF.

BMC Neurosci. 2017 Jan 5;18(1):8. doi: 10.1186/s12868-016-0323-2.


Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer.

Irving AA, Plum LA, Blaser WJ, Ford MR, Weng C, Clipson L, DeLuca HF, Dove WF.

J Nutr. 2015 Feb;145(2):291-8. doi: 10.3945/jn.114.204396. Epub 2014 Dec 24.


The utility of Apc-mutant rats in modeling human colon cancer.

Irving AA, Yoshimi K, Hart ML, Parker T, Clipson L, Ford MR, Kuramoto T, Dove WF, Amos-Landgraf JM.

Dis Model Mech. 2014 Nov;7(11):1215-25. doi: 10.1242/dmm.016980. Epub 2014 Oct 2. Review.


The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats.

Ivancic MM, Irving AA, Jonakin KG, Dove WF, Sussman MR.

Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9. doi: 10.1158/1940-6207.CAPR-14-0056. Epub 2014 Sep 8.


A simple, quantitative method using alginate gel to determine rat colonic tumor volume in vivo.

Irving AA, Young LB, Pleiman JK, Konrath MJ, Marzella B, Nonte M, Cacciatore J, Ford MR, Clipson L, Amos-Landgraf JM, Dove WF.

Comp Med. 2014 Apr;64(2):128-34.


Candidate serum biomarkers for early intestinal cancer using 15N metabolic labeling and quantitative proteomics in the ApcMin/+ mouse.

Ivancic MM, Huttlin EL, Chen X, Pleiman JK, Irving AA, Hegeman AD, Dove WF, Sussman MR.

J Proteome Res. 2013 Sep 6;12(9):4152-66. doi: 10.1021/pr400467c. Epub 2013 Aug 8.


Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms.

Amos-Landgraf JM, Irving AA, Hartman C, Hunter A, Laube B, Chen X, Clipson L, Newton MA, Dove WF.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2060-5. doi: 10.1073/pnas.1120753109. Epub 2012 Jan 23.


Mitigation of late renal and pulmonary injury after hematopoietic stem cell transplantation.

Cohen EP, Bedi M, Irving AA, Jacobs E, Tomic R, Klein J, Lawton CA, Moulder JE.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):292-6. doi: 10.1016/j.ijrobp.2011.05.081. Epub 2011 Nov 19.


Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models.

Irving AA, Halberg RB, Albrecht DM, Plum LA, Krentz KJ, Clipson L, Drinkwater N, Amos-Landgraf JM, Dove WF, DeLuca HF.

Arch Biochem Biophys. 2011 Nov;515(1-2):64-71. doi: 10.1016/ Epub 2011 Sep 1.


Radiation nephropathy is not mitigated by antagonists of oxidative stress.

Cohen EP, Fish BL, Irving AA, Rajapurkar MM, Shah SV, Moulder JE.

Radiat Res. 2009 Aug;172(2):260-4. doi: 10.1667/RR1739.


High-dose selenium for the mitigation of radiation injury: a pilot study in a rat model.

Sieber F, Muir SA, Cohen EP, North PE, Fish BL, Irving AA, M├Ąder M, Moulder JE.

Radiat Res. 2009 Mar;171(3):368-73. doi: 10.1667/0033-7587-171.3.368.


Chronic oxidative stress as a mechanism for radiation nephropathy.

Lenarczyk M, Cohen EP, Fish BL, Irving AA, Sharma M, Driscoll CD, Moulder JE.

Radiat Res. 2009 Feb;171(2):164-72. doi: 10.1667/RR1454.1.


Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates.

Halberg RB, Larsen MC, Elmergreen TL, Ko AY, Irving AA, Clipson L, Jefcoate CR.

Cancer Res. 2008 Sep 15;68(18):7394-402. doi: 10.1158/0008-5472.CAN-07-6750.


Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial.

Cohen EP, Irving AA, Drobyski WR, Klein JP, Passweg J, Talano JA, Juckett MB, Moulder JE.

Int J Radiat Oncol Biol Phys. 2008 Apr 1;70(5):1546-51. Epub 2007 Oct 29.


The Presence of a Nitrate Reducing Enzyme in Green Plants.

Irving AA, Hankinson R.

Biochem J. 1908;3(1-2):87-96. No abstract available.

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