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Items: 1 to 20 of 571

1.

Murine CD8 T Cell Functional Avidity is Stable In Vivo but not In Vitro: Independence from Homologous Prime/Boost Time Interval and Antigen Density.

Gilfillan CB, Wang C, Mohsen MO, Rufer N, Hebeisen M, Allard M, Verdeil G, Irvine DJ, Bachmann MF, Speiser DE.

Eur J Immunol. 2019 Nov 30. doi: 10.1002/eji.201948355. [Epub ahead of print]

PMID:
31785153
2.

DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8+ T Cell Compartment by Negatively Regulating Tonic TCR Triggering.

Mahajan VS, Demissie E, Alsufyani F, Kumari S, Yuen GJ, Viswanadham V, Huang A, Tran JQ, Moon JJ, Irvine DJ, Pillai S.

J Immunol. 2019 Nov 18. pii: ji1900440. doi: 10.4049/jimmunol.1900440. [Epub ahead of print]

PMID:
31740487
3.

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization.

Havenar-Daughton C, Carnathan DG, Boopathy AV, Upadhyay AA, Murrell B, Reiss SM, Enemuo CA, Gebru EH, Choe Y, Dhadvai P, Viviano F, Kaushik K, Bhiman JN, Briney B, Burton DR, Bosinger SE, Schief WR, Irvine DJ, Silvestri G, Crotty S.

Cell Rep. 2019 Nov 12;29(7):1756-1766.e8. doi: 10.1016/j.celrep.2019.10.008.

4.

Making Tablets for Delivery of Poorly Soluble Drugs Using Photoinitiated 3D Inkjet Printing.

Clark EA, Alexander MR, Irvine DJ, Roberts CJ, Wallace MJ, Yoo J, Wildman RD.

Int J Pharm. 2019 Nov 9:118805. doi: 10.1016/j.ijpharm.2019.118805. [Epub ahead of print]

PMID:
31715351
5.

Adaptive radiotherapy for head and neck cancer reduces the requirement for rescans during treatment due to spinal cord dose.

Belshaw L, Agnew CE, Irvine DM, Rooney KP, McGarry CK.

Radiat Oncol. 2019 Nov 1;14(1):189. doi: 10.1186/s13014-019-1400-3.

6.

A multilamellar nanoliposome stabilized by interlayer hydrogen bonds increases antimalarial drug efficacy.

Fotoran WL, M√ľntefering T, Kleiber N, Miranda BNM, Liebau E, Irvine DJ, Wunderlich G.

Nanomedicine. 2019 Oct 21;22:102099. doi: 10.1016/j.nano.2019.102099. [Epub ahead of print]

PMID:
31648039
7.

Not All T Cell Synapses Are Built the Same Way.

Kumari S, Colin-York H, Irvine DJ, Fritzsche M.

Trends Immunol. 2019 Nov;40(11):977-980. doi: 10.1016/j.it.2019.09.009. Epub 2019 Oct 20.

8.

Validating a Predictive Structure-Property Relationship by Discovery of Novel Polymers which Reduce Bacterial Biofilm Formation.

Dundas AA, Sanni O, Dubern JF, Dimitrakis G, Hook AL, Irvine DJ, Williams P, Alexander MR.

Adv Mater. 2019 Dec;31(49):e1903513. doi: 10.1002/adma.201903513. Epub 2019 Oct 3.

PMID:
31583791
9.

Donor cell engineering with GSK3 inhibitor-loaded nanoparticles enhances engraftment after in utero transplantation.

Loukogeorgakis SP, Fachin CG, Dias AIBS, Li H, Tang L, Kim AG, Vrecenak JD, Stratigis JD, Ahn NJ, Nissim I, Nissim I, Moron AF, Martins JL, Peranteau WH, De Coppi P, Irvine DJ, Flake AW.

Blood. 2019 Nov 28;134(22):1983-1995. doi: 10.1182/blood.2019001037.

PMID:
31570489
10.

Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles.

Melo M, Porter E, Zhang Y, Silva M, Li N, Dobosh B, Liguori A, Skog P, Landais E, Menis S, Sok D, Nemazee D, Schief WR, Weiss R, Irvine DJ.

Mol Ther. 2019 Dec 4;27(12):2080-2090. doi: 10.1016/j.ymthe.2019.08.007. Epub 2019 Aug 19.

PMID:
31515132
11.

Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid.

Al Sulaiman D, Chang JYH, Bennett NR, Topouzi H, Higgins CA, Irvine DJ, Ladame S.

ACS Nano. 2019 Aug 27;13(8):9620-9628. doi: 10.1021/acsnano.9b04783. Epub 2019 Aug 16.

12.

Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination.

Boopathy AV, Mandal A, Kulp DW, Menis S, Bennett NR, Watkins HC, Wang W, Martin JT, Thai NT, He Y, Schief WR, Hammond PT, Irvine DJ.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16473-16478. doi: 10.1073/pnas.1902179116. Epub 2019 Jul 29.

PMID:
31358641
13.

Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor.

Ma L, Dichwalkar T, Chang JYH, Cossette B, Garafola D, Zhang AQ, Fichter M, Wang C, Liang S, Silva M, Kumari S, Mehta NK, Abraham W, Thai N, Li N, Wittrup KD, Irvine DJ.

Science. 2019 Jul 12;365(6449):162-168. doi: 10.1126/science.aav8692.

14.

Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy.

Momin N, Mehta NK, Bennett NR, Ma L, Palmeri JR, Chinn MM, Lutz EA, Kang B, Irvine DJ, Spranger S, Wittrup KD.

Sci Transl Med. 2019 Jun 26;11(498). pii: eaaw2614. doi: 10.1126/scitranslmed.aaw2614.

PMID:
31243150
15.

Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study.

McNicholas BA, Rezoagli E, Pham T, Madotto F, Guiard E, Fanelli V, Bellani G, Griffin MD, Ranieri M, Laffey JG; ESICM Trials Group and the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) Investigators.

Crit Care Med. 2019 Sep;47(9):1216-1225. doi: 10.1097/CCM.0000000000003832.

PMID:
31162201
16.

Heat: An Overlooked Tool in the Practicing Hydrogeologist's Toolbox.

Kurylyk BL, Irvine DJ.

Ground Water. 2019 Jul;57(4):517-524. doi: 10.1111/gwat.12910. Epub 2019 Jun 20. No abstract available.

PMID:
31148145
17.

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West AP Jr, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC.

Nature. 2019 Jun;570(7762):468-473. doi: 10.1038/s41586-019-1250-z. Epub 2019 May 29.

18.

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.

Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S.

Cell. 2019 May 16;177(5):1153-1171.e28. doi: 10.1016/j.cell.2019.04.012. Epub 2019 May 9.

PMID:
31080066
19.

Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models.

Rothschilds A, Tzeng A, Mehta NK, Moynihan KD, Irvine DJ, Wittrup KD.

Oncoimmunology. 2019 Feb 19;8(5):e1558678. doi: 10.1080/2162402X.2018.1558678. eCollection 2019.

PMID:
31069130
20.

In vitro evolution of enhanced RNA replicons for immunotherapy.

Li Y, Teague B, Zhang Y, Su Z, Porter E, Dobosh B, Wagner T, Irvine DJ, Weiss R.

Sci Rep. 2019 May 6;9(1):6932. doi: 10.1038/s41598-019-43422-0.

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