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Items: 24

1.

Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro.

de Cabo R, Liu L, Ali A, Price N, Zhang J, Wang M, Lakatta E, Irusta PM.

Aging (Albany NY). 2015 Mar;7(3):152-66.

2.

Bacterial lysates improve the protective antibody response against respiratory viruses through Toll-like receptor 4.

Coviello S, Wimmenauer V, Polack FP, Irusta PM.

Hum Vaccin Immunother. 2014;10(10):2896-902. doi: 10.4161/hv.29784. Epub 2014 Nov 19.

3.

The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential.

Melzer IM, Fernández SB, Bösser S, Lohrig K, Lewandrowski U, Wolters D, Kehrloesser S, Brezniceanu ML, Theos AC, Irusta PM, Impens F, Gevaert K, Zörnig M.

Cell Death Differ. 2012 Sep;19(9):1435-45. doi: 10.1038/cdd.2012.17. Epub 2012 Mar 2.

4.

SRT1720 improves survival and healthspan of obese mice.

Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA, de Cabo R.

Sci Rep. 2011;1:70. doi: 10.1038/srep00070. Epub 2011 Aug 18. Erratum in: Sci Rep. 2013;3():1131.

5.

Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.

Birkenfeld AL, Lee HY, Guebre-Egziabher F, Alves TC, Jurczak MJ, Jornayvaz FR, Zhang D, Hsiao JJ, Martin-Montalvo A, Fischer-Rosinsky A, Spranger J, Pfeiffer AF, Jordan J, Fromm MF, König J, Lieske S, Carmean CM, Frederick DW, Weismann D, Knauf F, Irusta PM, De Cabo R, Helfand SL, Samuel VT, Shulman GI.

Cell Metab. 2011 Aug 3;14(2):184-95. doi: 10.1016/j.cmet.2011.06.009. Erratum in: Cell Metab. 2011 Oct 5;14(4):567.

6.

Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven.

Zou S, Chang J, LaFever L, Tang W, Johnson EL, Hu J, Wilk R, Krause HM, Drummond-Barbosa D, Irusta PM.

Cell Cycle. 2011 Mar 15;10(6):989-98. Epub 2011 Mar 15.

7.

Conserved cysteine residues within the attachment G glycoprotein of respiratory syncytial virus play a critical role in the enhancement of cytotoxic T-lymphocyte responses.

Melendi GA, Bridget D, Monsalvo AC, Laham FF, Acosta P, Delgado MF, Polack FP, Irusta PM.

Virus Genes. 2011 Feb;42(1):46-54. doi: 10.1007/s11262-010-0545-9. Epub 2010 Nov 4.

8.

Regulation of the ATM-activator protein Aven by CRM1-dependent nuclear export.

Esmaili AM, Johnson EL, Thaivalappil SS, Kuhn HM, Kornbluth S, Irusta PM.

Cell Cycle. 2010 Oct 1;9(19):3913-20. Epub 2010 Oct 25.

PMID:
20935510
9.

Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease.

Delgado MF, Coviello S, Monsalvo AC, Melendi GA, Hernandez JZ, Batalle JP, Diaz L, Trento A, Chang HY, Mitzner W, Ravetch J, Melero JA, Irusta PM, Polack FP.

Nat Med. 2009 Jan;15(1):34-41. doi: 10.1038/nm.1894. Epub 2008 Dec 14.

10.

Mitochondrial biogenesis and healthy aging.

López-Lluch G, Irusta PM, Navas P, de Cabo R.

Exp Gerontol. 2008 Sep;43(9):813-9. doi: 10.1016/j.exger.2008.06.014. Epub 2008 Jul 9. Review.

11.

Aven-dependent activation of ATM following DNA damage.

Guo JY, Yamada A, Kajino T, Wu JQ, Tang W, Freel CD, Feng J, Chau BN, Wang MZ, Margolis SS, Yoo HY, Wang XF, Dunphy WG, Irusta PM, Hardwick JM, Kornbluth S.

Curr Biol. 2008 Jul 8;18(13):933-42. doi: 10.1016/j.cub.2008.05.045. Epub 2008 Jun 19.

12.

IL-4 induces a wide-spectrum intracellular signaling cascade in CD8+ T cells.

Acacia de Sa Pinheiro A, Morrot A, Chakravarty S, Overstreet M, Bream JH, Irusta PM, Zavala F.

J Leukoc Biol. 2007 Apr;81(4):1102-10. Epub 2007 Jan 2.

PMID:
17200144
13.

C5 modulates airway hyperreactivity and pulmonary eosinophilia during enhanced respiratory syncytial virus disease by decreasing C3a receptor expression.

Melendi GA, Hoffman SJ, Karron RA, Irusta PM, Laham FR, Humbles A, Schofield B, Pan CH, Rabold R, Thumar B, Thumar A, Gerard NP, Mitzner W, Barnum SR, Gerard C, Kleeberger SR, Polack FP.

J Virol. 2007 Jan;81(2):991-9. Epub 2006 Nov 1.

14.

Anti-tumor therapeutic molecules that target the programmed cell death machinery.

Ivanovska I, Muhoro CN, Irusta PM.

Mini Rev Med Chem. 2006 Sep;6(9):1033-42. Review.

PMID:
17018002
15.

The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin.

Polack FP, Irusta PM, Hoffman SJ, Schiatti MP, Melendi GA, Delgado MF, Laham FR, Thumar B, Hendry RM, Melero JA, Karron RA, Collins PL, Kleeberger SR.

Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8996-9001. Epub 2005 Jun 14.

16.

Neuronal apoptosis pathways in Sindbis virus encephalitis.

Irusta PM, Hardwick JM.

Prog Mol Subcell Biol. 2004;36:71-93. Review.

PMID:
15171608
17.

Regulation of apoptosis by viruses that infect insects.

Irusta PM, Lamos E, Galonek HL, Vander Maten MA, Boersma MC, Chen YB, Hardwick JM.

Arch Virol Suppl. 2004;(18):171-8.

PMID:
15119772
18.

Viral modulators of cell death provide new links to old pathways.

Irusta PM, Chen YB, Hardwick JM.

Curr Opin Cell Biol. 2003 Dec;15(6):700-5. Review.

PMID:
14644194
19.

Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper.

Colón-Ramos DA, Irusta PM, Gan EC, Olson MR, Song J, Morimoto RI, Elliott RM, Lombard M, Hollingsworth R, Hardwick JM, Smith GK, Kornbluth S.

Mol Biol Cell. 2003 Oct;14(10):4162-72. Epub 2003 Jul 11.

20.

Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor.

Irusta PM, Luo Y, Bakht O, Lai CC, Smith SO, DiMaio D.

J Biol Chem. 2002 Oct 11;277(41):38627-34. Epub 2002 Aug 13.

22.

Oncogenic activation of the PDGF beta receptor by the transmembrane domain of p185neu*.

Petti LM, Irusta PM, DiMaio D.

Oncogene. 1998 Feb 19;16(7):843-51.

23.

Amino acid tandem repeats within a late viral gene define the central variable region of African swine fever virus.

Irusta PM, Borca MV, Kutish GF, Lu Z, Caler E, Carrillo C, Rock DL.

Virology. 1996 Jun 1;220(1):20-7.

24.

A structural DNA binding protein of African swine fever virus with similarity to bacterial histone-like proteins.

Borca MV, Irusta PM, Kutish GF, Carillo C, Afonso CL, Burrage AT, Neilan JG, Rock DL.

Arch Virol. 1996;141(2):301-13.

PMID:
8634022

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