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Items: 1 to 50 of 168

1.

A dual origin for blood vessels.

Iruela-Arispe ML.

Nature. 2018 Oct;562(7726):195-197. doi: 10.1038/d41586-018-06199-2. No abstract available.

PMID:
30291309
2.

Pumping blood with self-reliance and cooperation.

Iruela-Arispe ML.

J Exp Med. 2018 Oct 1;215(10):2480-2482. doi: 10.1084/jem.20181537. Epub 2018 Sep 18.

PMID:
30228158
3.

Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities.

McDonald AI, Shirali AS, Aragón R, Ma F, Hernandez G, Vaughn DA, Mack JJ, Lim TY, Sunshine H, Zhao P, Kalinichenko V, Hai T, Pelegrini M, Ardehali R, Iruela-Arispe ML.

Cell Stem Cell. 2018 Aug 2;23(2):210-225.e6. doi: 10.1016/j.stem.2018.07.011.

PMID:
30075129
4.

Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue.

Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA.

J Vis Exp. 2018 Jun 21;(136). doi: 10.3791/57760.

PMID:
29985359
5.

Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer.

Chattopadhyay A, Yang X, Mukherjee P, Sulaiman D, Fogelman HR, Grijalva V, Dubinett S, Wasler TC, Paul MK, Salehi-Rad R, Mack JJ, Iruela-Arispe ML, Navab M, Fogelman AM, Reddy ST.

Sci Rep. 2018 Jun 13;8(1):9032. doi: 10.1038/s41598-018-26755-0.

6.

Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.

Hilfenhaus G, Nguyen DP, Freshman J, Prajapati D, Ma F, Song D, Ziyad S, Cuadrado M, Pellegrini M, Bustelo XR, Iruela-Arispe ML.

J Cell Biol. 2018 Aug 6;217(8):2813-2830. doi: 10.1083/jcb.201706041. Epub 2018 Jun 1.

PMID:
29858212
7.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 May 15. doi: 10.1007/s10456-018-9613-x. [Epub ahead of print] Review.

8.

Metastasis of Circulating Tumor Cells: Speed Matters.

Freitas VM, Hilfenhaus G, Iruela-Arispe ML.

Dev Cell. 2018 Apr 9;45(1):3-5. doi: 10.1016/j.devcel.2018.03.005.

PMID:
29634934
9.

A multi-step transcriptional cascade underlies vascular regeneration in vivo.

Shirali AS, Romay MC, McDonald AI, Su T, Steel ME, Iruela-Arispe ML.

Sci Rep. 2018 Apr 3;8(1):5430. doi: 10.1038/s41598-018-23653-3.

10.

GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth.

Li L, Zeng Q, Bhutkar A, Galván JA, Karamitopoulou E, Noordermeer D, Peng MW, Piersigilli A, Perren A, Zlobec I, Robinson H, Iruela-Arispe ML, Hanahan D.

Cancer Cell. 2018 Apr 9;33(4):736-751.e5. doi: 10.1016/j.ccell.2018.02.011. Epub 2018 Mar 29.

11.

NOTCH regulation of the endothelial cell phenotype.

Mack JJ, Iruela-Arispe ML.

Curr Opin Hematol. 2018 May;25(3):212-218. doi: 10.1097/MOH.0000000000000425.

12.

Analysis of cardiomyocyte clonal expansion during mouse heart development and injury.

Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R.

Nat Commun. 2018 Feb 21;9(1):754. doi: 10.1038/s41467-018-02891-z.

13.

A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.

Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML.

Cell Rep. 2018 Jan 30;22(5):1211-1224. doi: 10.1016/j.celrep.2018.01.017.

14.

NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot.

Duran I, Tenney J, Warren CM, Sarukhanov A, Csukasi F, Skalansky M, Iruela-Arispe ML, Krakow D.

Am J Med Genet A. 2018 Mar;176(3):649-656. doi: 10.1002/ajmg.a.38600. Epub 2018 Jan 24.

PMID:
29363855
15.

HIF-1α Deletion in the Endothelium, but Not in the Epithelium, Protects From Radiation-Induced Enteritis.

Toullec A, Buard V, Rannou E, Tarlet G, Guipaud O, Robine S, Iruela-Arispe ML, François A, Milliat F.

Cell Mol Gastroenterol Hepatol. 2017 Aug 16;5(1):15-30. doi: 10.1016/j.jcmgh.2017.08.001. eCollection 2018.

16.

Endothelial permeability, LDL deposition, and cardiovascular risk factors-a review.

Mundi S, Massaro M, Scoditti E, Carluccio MA, van Hinsbergh VWM, Iruela-Arispe ML, De Caterina R.

Cardiovasc Res. 2018 Jan 1;114(1):35-52. doi: 10.1093/cvr/cvx226.

PMID:
29228169
17.

NOTCH1 is a mechanosensor in adult arteries.

Mack JJ, Mosqueiro TS, Archer BJ, Jones WM, Sunshine H, Faas GC, Briot A, Aragón RL, Su T, Romay MC, McDonald AI, Kuo CH, Lizama CO, Lane TF, Zovein AC, Fang Y, Tarling EJ, de Aguiar Vallim TQ, Navab M, Fogelman AM, Bouchard LS, Iruela-Arispe ML.

Nat Commun. 2017 Nov 20;8(1):1620. doi: 10.1038/s41467-017-01741-8.

18.

Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice.

Mintet E, Lavigne J, Paget V, Tarlet G, Buard V, Guipaud O, Sabourin JC, Iruela-Arispe ML, Milliat F, François A.

Sci Rep. 2017 Jul 10;7(1):4933. doi: 10.1038/s41598-017-05389-8.

19.

Membrane lipids and cell signaling.

Sunshine H, Iruela-Arispe ML.

Curr Opin Lipidol. 2017 Oct;28(5):408-413. doi: 10.1097/MOL.0000000000000443. Review.

20.

Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum.

Mukherjee P, Hough G, Chattopadhyay A, Navab M, Fogelman HR, Meriwether D, Williams K, Bensinger S, Moller T, Faull KF, Lusis AJ, Iruela-Arispe ML, Bostrom KI, Tontonoz P, Reddy ST, Fogelman AM.

J Lipid Res. 2017 Aug;58(8):1636-1647. doi: 10.1194/jlr.M076554. Epub 2017 Jun 7.

21.

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model.

Shirali AS, McDonald AI, Mack JJ, Iruela-Arispe ML.

J Vis Exp. 2016 Nov 24;(117). doi: 10.3791/54755.

PMID:
27911412
22.

Perivascular Macrophages Limit Permeability.

He H, Mack JJ, Güç E, Warren CM, Squadrito ML, Kilarski WW, Baer C, Freshman RD, McDonald AI, Ziyad S, Swartz MA, De Palma M, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2203-2212. Epub 2016 Sep 15.

23.

Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy.

Inkeles MS, Teles RM, Pouldar D, Andrade PR, Madigan CA, Lopez D, Ambrose M, Noursadeghi M, Sarno EN, Rea TH, Ochoa MT, Iruela-Arispe ML, Swindell WR, Ottenhoff TH, Geluk A, Bloom BR, Pellegrini M, Modlin RL.

JCI Insight. 2016 Sep 22;1(15):e88843.

24.

Notch, lipids, and endothelial cells.

Briot A, Bouloumié A, Iruela-Arispe ML.

Curr Opin Lipidol. 2016 Oct;27(5):513-20. doi: 10.1097/MOL.0000000000000337. Review.

25.

Cross-talk between signaling and metabolism in the vasculature.

Uebelhoer M, Iruela-Arispe ML.

Vascul Pharmacol. 2016 Aug;83:4-9. doi: 10.1016/j.vph.2016.06.002. Epub 2016 Jun 9. Review.

26.

4-D Flow Control in Porous Scaffolds: Toward a Next Generation of Bioreactors.

Youssef K, Jarenwattananon NN, Archer BJ, Mack J, Iruela-Arispe ML, Bouchard LS.

IEEE Trans Biomed Eng. 2017 Jan;64(1):61-69. doi: 10.1109/TBME.2016.2537266. Epub 2016 Mar 2.

PMID:
26955013
27.

Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.

Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML.

J Exp Med. 2015 Nov 16;212(12):2147-63. doi: 10.1084/jem.20150603. Epub 2015 Nov 9.

28.

In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury.

Rannou E, François A, Toullec A, Guipaud O, Buard V, Tarlet G, Mintet E, Jaillet C, Iruela-Arispe ML, Benderitter M, Sabourin JC, Milliat F.

Sci Rep. 2015 Oct 29;5:15738. doi: 10.1038/srep15738.

29.

Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells.

Hernández-García R, Iruela-Arispe ML, Reyes-Cruz G, Vázquez-Prado J.

Vascul Pharmacol. 2015 Nov;74:60-72. doi: 10.1016/j.vph.2015.10.003. Epub 2015 Oct 17.

PMID:
26471833
30.

Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer.

Moughon DL, He H, Schokrpur S, Jiang ZK, Yaqoob M, David J, Lin C, Iruela-Arispe ML, Dorigo O, Wu L.

Cancer Res. 2015 Nov 15;75(22):4742-52. doi: 10.1158/0008-5472.CAN-14-3373. Epub 2015 Oct 15.

31.

Healing arterial ulcers: Endothelial lining regeneration upon vascular denudation injury.

McDonald AI, Iruela-Arispe ML.

Vascul Pharmacol. 2015 Sep;72:9-15. doi: 10.1016/j.vph.2015.06.007. Epub 2015 Jun 18. Review.

32.

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.

Domigan CK, Warren CM, Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, Iruela-Arispe ML.

J Cell Sci. 2015 Jun 15;128(12):2236-48. doi: 10.1242/jcs.163774. Epub 2015 May 8.

33.

State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association.

Simons M, Alitalo K, Annex BH, Augustin HG, Beam C, Berk BC, Byzova T, Carmeliet P, Chilian W, Cooke JP, Davis GE, Eichmann A, Iruela-Arispe ML, Keshet E, Sinusas AJ, Ruhrberg C, Woo YJ, Dimmeler S; American Heart Association Council on Basic Cardiovascular Sciences and Council on Cardiovascular Surgery and Anesthesia.

Circ Res. 2015 May 22;116(11):e99-132. doi: 10.1161/RES.0000000000000054. Epub 2015 Apr 30. No abstract available.

PMID:
25931450
34.

ADAMTS proteases in vascular biology.

Rodríguez-Manzaneque JC, Fernández-Rodríguez R, Rodríguez-Baena FJ, Iruela-Arispe ML.

Matrix Biol. 2015 May-Jul;44-46:38-45. doi: 10.1016/j.matbio.2015.02.004. Epub 2015 Feb 17. Review.

35.

Blockade of specific NOTCH ligands: a new promising approach in cancer therapy.

Briot A, Iruela-Arispe ML.

Cancer Discov. 2015 Feb;5(2):112-4. doi: 10.1158/2159-8290.CD-14-1501.

36.

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML.

Dev Cell. 2014 Dec 22;31(6):707-21. doi: 10.1016/j.devcel.2014.11.023.

37.

Stealing VEGF from thy neighbor.

Domigan CK, Iruela-Arispe ML.

Cell. 2014 Oct 23;159(3):473-4. doi: 10.1016/j.cell.2014.10.008.

38.

Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction.

Domigan CK, Ziyad S, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):30-9. doi: 10.1161/ATVBAHA.114.303215. Epub 2014 Oct 2. Review.

39.

Podosome rosettes precede vascular sprouts in tumour angiogenesis.

Warren CM, Iruela-Arispe ML.

Nat Cell Biol. 2014 Oct;16(10):928-30. doi: 10.1038/ncb3044.

PMID:
25271481
40.

The chicken chorioallantoic membrane model in biology, medicine and bioengineering.

Nowak-Sliwinska P, Segura T, Iruela-Arispe ML.

Angiogenesis. 2014 Oct;17(4):779-804. doi: 10.1007/s10456-014-9440-7. Epub 2014 Aug 20. Review.

41.

Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.

Michael IP, Westenskow PD, Hacibekiroglu S, Greenwald AC, Ballios BG, Kurihara T, Li Z, Warren CM, Zhang P, Aguilar E, Donaldson L, Marchetti V, Baba T, Hussein SM, Sung HK, Iruela-Arispe ML, Rini JM, van der Kooy D, Friedlander M, Nagy A.

EMBO Mol Med. 2014 May;6(5):604-23. doi: 10.1002/emmm.201303708.

42.

Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation.

Goddard LM, Murphy TJ, Org T, Enciso JM, Hashimoto-Partyka MK, Warren CM, Domigan CK, McDonald AI, He H, Sanchez LA, Allen NC, Orsenigo F, Chao LC, Dejana E, Tontonoz P, Mikkola HK, Iruela-Arispe ML.

Cell. 2014 Jan 30;156(3):549-62. doi: 10.1016/j.cell.2013.12.025.

43.

Hybrid photopatterned enzymatic reaction (HyPER) for in situ cell manipulation.

Griffin DR, Borrajo J, Soon A, Acosta-Vélez GF, Oshita V, Darling N, Mack J, Barker T, Iruela-Arispe ML, Segura T.

Chembiochem. 2014 Jan 24;15(2):233-42. doi: 10.1002/cbic.201300687. Epub 2014 Jan 7. Erratum in: Chembiochem. 2014 Mar 3;15(4):485-6.

44.

A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes.

Warren CM, Ziyad S, Briot A, Der A, Iruela-Arispe ML.

Sci Signal. 2014 Jan 7;7(307):ra1. doi: 10.1126/scisignal.2004235.

45.

Sox17 is indispensable for acquisition and maintenance of arterial identity.

Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E.

Nat Commun. 2013;4:2609. doi: 10.1038/ncomms3609.

46.

The mouse retina in 3D: quantification of vascular growth and remodeling.

Milde F, Lauw S, Koumoutsakos P, Iruela-Arispe ML.

Integr Biol (Camb). 2013 Dec;5(12):1426-38. doi: 10.1039/c3ib40085a.

PMID:
24136100
47.

β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.

Turlo KA, Scapa J, Bagher P, Jones AW, Feil R, Korthuis RJ, Segal SS, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2325-35. doi: 10.1161/ATVBAHA.112.300648. Epub 2013 Jul 25.

48.

Tubulogenesis.

Iruela-Arispe ML, Beitel GJ.

Development. 2013 Jul;140(14):2851-5. doi: 10.1242/dev.070680. Review.

49.

Selective suppression of endothelial cytokine production by progesterone receptor.

Goddard LM, Ton AN, Org T, Mikkola HK, Iruela-Arispe ML.

Vascul Pharmacol. 2013 Jul-Aug;59(1-2):36-43. doi: 10.1016/j.vph.2013.06.001. Epub 2013 Jun 6.

50.

Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy.

Janzen DM, Rosales MA, Paik DY, Lee DS, Smith DA, Witte ON, Iruela-Arispe ML, Memarzadeh S.

Cancer Res. 2013 Aug 1;73(15):4697-710. doi: 10.1158/0008-5472.CAN-13-0930. Epub 2013 Jun 6.

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