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Items: 1 to 50 of 301

1.

Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas - Implications for the progression of EGFR-mutated lung adenocarcinomas.

Matsumura M, Okudela K, Nakashima Y, Mitsui H, Denda-Nagai K, Suzuki T, Arai H, Umeda S, Tateishi Y, Koike C, Kataoka T, Irimura T, Ohashi K.

PLoS One. 2019 Apr 11;14(4):e0215237. doi: 10.1371/journal.pone.0215237. eCollection 2019.

2.

Incorporation, intracellular trafficking and processing of extracellular heparanase by mast cells: Involvement of syndecan-4-dependent pathway.

Higashi N, Waki M, Sudo Y, Suzuki S, Oku T, Tsuiji M, Tsuji T, Miyagishi M, Takahashi K, Nakajima M, Irimura T.

Biochem Biophys Res Commun. 2018 Sep 18;503(4):3235-3241. doi: 10.1016/j.bbrc.2018.08.132. Epub 2018 Aug 24.

PMID:
30149916
3.

A Critical Domain of Ebolavirus Envelope Glycoprotein Determines Glycoform and Infectivity.

Fujihira H, Usami K, Matsuno K, Takeuchi H, Denda-Nagai K, Furukawa JI, Shinohara Y, Takada A, Kawaoka Y, Irimura T.

Sci Rep. 2018 Apr 3;8(1):5495. doi: 10.1038/s41598-018-23357-8.

4.

Corrigendum: Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology.

Adachi H, Nakae K, Sakamoto S, Nosaka C, Atsumi S, Shibuya M, Higashi N, Nakajima M, Irimura T, Nishimura Y.

J Antibiot (Tokyo). 2018 Feb;71(2):349. doi: 10.1038/ja.2017.149.

PMID:
29375138
5.

Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology.

Adachi H, Nakae K, Sakamoto S, Nosaka C, Atsumi S, Shibuya M, Higashi N, Nakajima M, Irimura T, Nishimura Y.

J Antibiot (Tokyo). 2017 Nov 1. doi: 10.1038/ja.2017.138. [Epub ahead of print] Review. Erratum in: J Antibiot (Tokyo). 2018 Feb;71(2):349.

PMID:
29089599
6.

Proteasome Inhibitor-Loaded Micelles Enhance Antitumor Activity Through Macrophage Reprogramming by NF-κB Inhibition.

Wu H, Tao A, Martin JD, Quader S, Liu X, Takahashi K, Hespel L, Miura Y, Hayakawa Y, Irimura T, Cabral H, Kataoka K.

J Pharm Sci. 2017 Sep;106(9):2438-2446. doi: 10.1016/j.xphs.2017.03.031. Epub 2017 Apr 12.

PMID:
28412401
7.

IL-17A-producing CD30(+) Vδ1 T cells drive inflammation-induced cancer progression.

Kimura Y, Nagai N, Tsunekawa N, Sato-Matsushita M, Yoshimoto T, Cua DJ, Iwakura Y, Yagita H, Okada F, Tahara H, Saiki I, Irimura T, Hayakawa Y.

Cancer Sci. 2016 Sep;107(9):1206-14. doi: 10.1111/cas.13005. Epub 2016 Sep 1.

8.

An iminosugar-based heparanase inhibitor heparastatin (SF4) suppresses infiltration of neutrophils and monocytes into inflamed dorsal air pouches.

Sue M, Higashi N, Shida H, Kogane Y, Nishimura Y, Adachi H, Kolaczkowska E, Kepka M, Nakajima M, Irimura T.

Int Immunopharmacol. 2016 Jun;35:15-21. doi: 10.1016/j.intimp.2016.03.017. Epub 2016 Mar 22.

PMID:
27015605
9.

Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs.

Hayakawa Y, Kawada M, Nishikawa H, Ochiya T, Saya H, Seimiya H, Yao R, Hayashi M, Kai C, Matsuda A, Naoe T, Ohtsu A, Okazaki T, Saji H, Sata M, Sugimura H, Sugiyama Y, Toi M, Irimura T.

Cancer Sci. 2016 Feb;107(2):189-202. doi: 10.1111/cas.12857. Review.

10.

Heparanase augments inflammatory chemokine production from colorectal carcinoma cell lines.

Tsunekawa N, Higashi N, Kogane Y, Waki M, Shida H, Nishimura Y, Adachi H, Nakajima M, Irimura T.

Biochem Biophys Res Commun. 2016 Jan 22;469(4):878-83. doi: 10.1016/j.bbrc.2015.12.074. Epub 2015 Dec 20.

PMID:
26713365
11.

POMGNT1 Is Glycosylated by Mucin-Type O-Glycans.

Xin X, Akasaka-Manya K, Manya H, Furukawa J, Kuwahara N, Okada K, Tsumoto H, Higashi N, Kato R, Shinohara Y, Irimura T, Endo T.

Biol Pharm Bull. 2015;38(9):1389-94. doi: 10.1248/bpb.b15-00415.

12.

Lectin Microarray-Based Sero-Biomarker Verification Targeting Aberrant O-Linked Glycosylation on Mucin 1.

Matsuda A, Kuno A, Nakagawa T, Ikehara Y, Irimura T, Yamamoto M, Nakanuma Y, Miyoshi E, Nakamori S, Nakanishi H, Viwatthanasittiphong C, Srivatanakul P, Miwa M, Shoda J, Narimatsu H.

Anal Chem. 2015 Jul 21;87(14):7274-81. doi: 10.1021/acs.analchem.5b01329. Epub 2015 Jul 7.

PMID:
26091356
13.

Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation.

Takahashi K, Nagai N, Ogura K, Tsuneyama K, Saiki I, Irimura T, Hayakawa Y.

Cancer Sci. 2015 Jul;106(7):867-74. doi: 10.1111/cas.12685. Epub 2015 May 29.

14.

CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages.

Kee JY, Ito A, Hojo S, Hashimoto I, Igarashi Y, Tsuneyama K, Tsukada K, Irimura T, Shibahara N, Takasaki I, Inujima A, Nakayama T, Yoshie O, Sakurai H, Saiki I, Koizumi K.

BMC Cancer. 2014 Dec 15;14:949. doi: 10.1186/1471-2407-14-949.

15.

Identification of Hirsutine as an anti-metastatic phytochemical by targeting NF-κB activation.

Lou C, Takahashi K, Irimura T, Saiki I, Hayakawa Y.

Int J Oncol. 2014 Nov;45(5):2085-91. doi: 10.3892/ijo.2014.2624. Epub 2014 Aug 27.

PMID:
25175557
16.

Interaction of Muc4 and ErbB2 in a transgenic mouse model of gallbladder carcinoma: potential pathobiological implications.

Miyahara N, Shoda J, Kawamoto T, Ishida H, Ueda T, Akimoto Y, Kawakami H, Irimura T.

Oncol Rep. 2014 Nov;32(5):1796-802. doi: 10.3892/or.2014.3443. Epub 2014 Aug 25.

PMID:
25174601
17.

Up-regulation of neogenin-1 increases cell proliferation and motility in gastric cancer.

Kim SJ, Wang YG, Lee HW, Kang HG, La SH, Choi IJ, Irimura T, Ro JY, Bresalier RS, Chun KH.

Oncotarget. 2014 May 30;5(10):3386-98.

18.

Heparanase-mediated cleavage of macromolecular heparin accelerates release of granular components of mast cells from extracellular matrices.

Higashi N, Waki M, Sue M, Kogane Y, Shida H, Tsunekawa N, Hasan A, Sato T, Kitahara A, Kasaoka T, Hayakawa Y, Nakajima M, Irimura T.

Biochem J. 2014 Mar 1;458(2):291-9. doi: 10.1042/BJ20131463.

PMID:
24344642
19.

The macrophage galactose-type lectin can function as an attachment and entry receptor for influenza virus.

Ng WC, Liong S, Tate MD, Irimura T, Denda-Nagai K, Brooks AG, Londrigan SL, Reading PC.

J Virol. 2014 Feb;88(3):1659-72. doi: 10.1128/JVI.02014-13. Epub 2013 Nov 20.

20.

A unique dermal dendritic cell subset that skews the immune response toward Th2.

Murakami R, Denda-Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T.

PLoS One. 2013 Sep 9;8(9):e73270. doi: 10.1371/journal.pone.0073270. eCollection 2013. Erratum in: PLoS One. 2014;9(3):e93236.

21.

Enhancement of in vitro cell motility and invasiveness of human malignant pleural mesothelioma cells through the HIF-1α-MUC1 pathway.

Goudarzi H, Iizasa H, Furuhashi M, Nakazawa S, Nakane R, Liang S, Hida Y, Yanagihara K, Kubo T, Nakagawa K, Kobayashi M, Irimura T, Hamada J.

Cancer Lett. 2013 Oct 1;339(1):82-92. doi: 10.1016/j.canlet.2013.07.020. Epub 2013 Jul 20.

22.

Functional roles of tumor necrosis factor-related apoptosis-inducing ligand-DR5 interaction in B16F10 cells by activating the nuclear factor-κB pathway to induce metastatic potential.

Takahashi K, Takeda K, Saiki I, Irimura T, Hayakawa Y.

Cancer Sci. 2013 May;104(5):558-62. doi: 10.1111/cas.12112. Epub 2013 Feb 28.

23.

Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model.

Kee JY, Ito A, Hojo S, Hashimoto I, Igarashi Y, Tsukada K, Irimura T, Shibahara N, Nakayama T, Yoshie O, Sakurai H, Saiki I, Koizumi K.

Oncol Rep. 2013 Mar;29(3):975-82. doi: 10.3892/or.2012.2185. Epub 2012 Dec 13.

PMID:
23242131
24.

Local effects of regulatory T cells in MUC1 transgenic mice potentiate growth of MUC1 expressing tumor cells in vivo.

Sugiura D, Denda-Nagai K, Takashima M, Murakami R, Nagai S, Takeda K, Irimura T.

PLoS One. 2012;7(9):e44770. doi: 10.1371/journal.pone.0044770. Epub 2012 Sep 17.

25.

Cytokine secretion from human monocytes potentiated by P-selectin-mediated cell adhesion.

Suzuki J, Hamada E, Shodai T, Kamoshida G, Kudo S, Itoh S, Koike J, Nagata K, Irimura T, Tsuji T.

Int Arch Allergy Immunol. 2013;160(2):152-60. doi: 10.1159/000339857. Epub 2012 Sep 25.

27.

Establishment of phosphatidylinositol 3-kinase inhibitor-resistant cancer cell lines and therapeutic strategies for overcoming the resistance.

Isoyama S, Dan S, Nishimura Y, Nakamura N, Kajiwara G, Seki M, Irimura T, Yamori T.

Cancer Sci. 2012 Nov;103(11):1955-60. doi: 10.1111/cas.12004. Epub 2012 Oct 22.

28.

Mucin 21 in esophageal squamous epithelia and carcinomas: analysis with glycoform-specific monoclonal antibodies.

Tian Y, Denda-Nagai K, Kamata-Sakurai M, Nakamori S, Tsukui T, Itoh Y, Okada K, Yi Y, Irimura T.

Glycobiology. 2012 Sep;22(9):1218-26. doi: 10.1093/glycob/cws082. Epub 2012 May 19.

PMID:
22611128
29.

Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.

Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M.

Eur J Immunol. 2012 Apr;42(4):936-45. doi: 10.1002/eji.201142086.

30.

Cell surface expression of hyaluronan on human ovarian cancer cells inversely correlates with their adhesion to peritoneal mesothelial cells.

Tamada Y, Takeuchi H, Suzuki N, Aoki D, Irimura T.

Tumour Biol. 2012 Aug;33(4):1215-22. doi: 10.1007/s13277-012-0369-4. Epub 2012 Mar 6.

PMID:
22392500
31.

Monocyte differentiation induced by co-culture with tumor cells involves RGD-dependent cell adhesion to extracellular matrix.

Kamoshida G, Matsuda A, Sekine W, Mizuno H, Oku T, Itoh S, Irimura T, Tsuji T.

Cancer Lett. 2012 Feb 28;315(2):145-52. doi: 10.1016/j.canlet.2011.09.029. Epub 2011 Nov 2.

PMID:
22104730
32.

Toshiaki Osawa: biochemistry of lectins and their applications in immunochemistry and cellular biology.

Yamamoto K, Irimura T.

J Biochem. 2011 Nov;150(5):477-82. doi: 10.1093/jb/mvr033.

PMID:
22039277
33.

Asialoglycoprotein receptor promotes cancer metastasis by activating the EGFR-ERK pathway.

Ueno S, Mojic M, Ohashi Y, Higashi N, Hayakawa Y, Irimura T.

Cancer Res. 2011 Oct 15;71(20):6419-27. doi: 10.1158/0008-5472.CAN-11-1773. Epub 2011 Aug 25.

34.

Early activation and interferon-γ production of tumor-infiltrating mature CD27 high natural killer cells.

Hayakawa Y, Sato-Matsushita M, Takeda K, Iwakura Y, Tahara H, Irimura T.

Cancer Sci. 2011 Nov;102(11):1967-71. doi: 10.1111/j.1349-7006.2011.02042.x. Epub 2011 Aug 21.

35.

Involvement of viral envelope GP2 in Ebola virus entry into cells expressing the macrophage galactose-type C-type lectin.

Usami K, Matsuno K, Igarashi M, Denda-Nagai K, Takada A, Irimura T.

Biochem Biophys Res Commun. 2011 Apr 1;407(1):74-8. doi: 10.1016/j.bbrc.2011.02.110. Epub 2011 Mar 6.

PMID:
21362405
36.

C-type lectins do not act as functional receptors for filovirus entry into cells.

Matsuno K, Nakayama E, Noyori O, Marzi A, Ebihara H, Irimura T, Feldmann H, Takada A.

Biochem Biophys Res Commun. 2010 Dec 3;403(1):144-8. doi: 10.1016/j.bbrc.2010.10.136. Epub 2010 Nov 5.

37.

Expression and the role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma.

Kamiyama S, Ichimiya T, Ikehara Y, Takase T, Fujimoto I, Suda T, Nakamori S, Nakamura M, Nakayama F, Irimura T, Nakanishi H, Watanabe M, Narimatsu H, Nishihara S.

Glycobiology. 2011 Feb;21(2):235-46. doi: 10.1093/glycob/cwq154. Epub 2010 Oct 25.

PMID:
20978009
38.

Organ microenvironment plays significant roles through Fas ligand in vaccine-induced CD4(+) T cell dependent suppression of tumor growth at the orthotopic site.

Sugiura D, Denda-Nagai K, Takeda K, Irimura T.

Cancer Sci. 2010 Sep;101(9):1965-9. doi: 10.1111/j.1349-7006.2010.01634.x.

39.

Wisteria floribunda agglutinin-positive mucin 1 is a sensitive biliary marker for human cholangiocarcinoma.

Matsuda A, Kuno A, Kawamoto T, Matsuzaki H, Irimura T, Ikehara Y, Zen Y, Nakanuma Y, Yamamoto M, Ohkohchi N, Shoda J, Hirabayashi J, Narimatsu H.

Hepatology. 2010 Jul;52(1):174-82. doi: 10.1002/hep.23654.

PMID:
20578261
40.

Mucin 21/epiglycanin modulates cell adhesion.

Yi Y, Kamata-Sakurai M, Denda-Nagai K, Itoh T, Okada K, Ishii-Schrade K, Iguchi A, Sugiura D, Irimura T.

J Biol Chem. 2010 Jul 9;285(28):21233-40. doi: 10.1074/jbc.M109.082875. Epub 2010 Apr 13.

41.

Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells.

Denda-Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo-Puthinan S, Tsuiji M, Morikawa A, Kumamoto Y, Sugiura D, Kudo A, Akimoto Y, Kawakami H, Bovin NV, Irimura T.

J Biol Chem. 2010 Jun 18;285(25):19193-204. doi: 10.1074/jbc.M110.113613. Epub 2010 Mar 19.

42.

Different potential of C-type lectin-mediated entry between Marburg virus strains.

Matsuno K, Kishida N, Usami K, Igarashi M, Yoshida R, Nakayama E, Shimojima M, Feldmann H, Irimura T, Kawaoka Y, Takada A.

J Virol. 2010 May;84(10):5140-7. doi: 10.1128/JVI.02021-09. Epub 2010 Mar 10.

43.

Macrophage receptors for influenza A virus: role of the macrophage galactose-type lectin and mannose receptor in viral entry.

Upham JP, Pickett D, Irimura T, Anders EM, Reading PC.

J Virol. 2010 Apr;84(8):3730-7. doi: 10.1128/JVI.02148-09. Epub 2010 Jan 27.

44.

Loss of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 and reduced O-glycosylation in colon carcinoma cells selected for hepatic metastasis.

Kato K, Takeuchi H, Kanoh A, Miyahara N, Nemoto-Sasaki Y, Morimoto-Tomita M, Matsubara A, Ohashi Y, Waki M, Usami K, Mandel U, Clausen H, Higashi N, Irimura T.

Glycoconj J. 2010 Feb;27(2):267-76. doi: 10.1007/s10719-009-9275-4.

PMID:
20077002
45.

Potentiation of proliferation of some but not all human colon carcinoma cell lines by immobilized hepatic asialoglycoprotein receptor 1.

Fang J, Izawa R, Gomez-Santos L, Ueno S, Sawaguchi T, Usami K, Nodera Y, Takeuchi H, Ohashi Y, Higashi N, Irimura T.

Oncol Res. 2009;17(10):437-45.

PMID:
19725223
46.

MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo.

Kumamoto Y, Denda-Nagai K, Aida S, Higashi N, Irimura T.

PLoS One. 2009;4(5):e5619. doi: 10.1371/journal.pone.0005619. Epub 2009 May 19.

47.

A library of mutated Maackia amurensis hemagglutinin distinguishes putative glycoforms of immunoglobulin A1 from IgA nephropathy patients.

Maenuma K, Yim M, Komatsu K, Hoshino M, Tachiki-Fujioka A, Takahashi K, Hiki Y, Bovin N, Irimura T.

J Proteome Res. 2009 Jul;8(7):3617-24. doi: 10.1021/pr800816w.

PMID:
19368344
48.

A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis.

Saba K, Denda-Nagai K, Irimura T.

Am J Pathol. 2009 Jan;174(1):144-52. doi: 10.2353/ajpath.2009.080235. Epub 2008 Dec 18.

49.

With those pressures, there have been more cases of plagiarism, scientific fraud and misconduct.

Eccles S, Irimura T, Welch D.

Clin Exp Metastasis. 2009;26(1):1. doi: 10.1007/s10585-008-9229-4. No abstract available.

PMID:
19089592
50.

Differential effector mechanisms induced by vaccination with MUC1 DNA in the rejection of colon carcinoma growth at orthotopic sites and metastases.

Sugiura D, Aida S, Denda-Nagai K, Takeda K, Kamata-Sakurai M, Yagita H, Irimura T.

Cancer Sci. 2008 Dec;99(12):2477-84. doi: 10.1111/j.1349-7006.2008.00967.x. Epub 2008 Nov 17.

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