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Items: 1 to 50 of 138

1.

Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.

Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2018 Aug 3;3(26). pii: eaao4747. doi: 10.1126/sciimmunol.aao4747.

PMID:
30076281
2.

Impact of toll-like receptor 4 stimulation on human neonatal neutrophil spontaneous migration, transcriptomics, and cytokine production.

Raymond SL, Hawkins RB, Murphy TJ, Rincon JC, Stortz JA, López MC, Ungaro R, Ellett F, Baker HV, Wynn JL, Moldawer LL, Irimia D, Larson SD.

J Mol Med (Berl). 2018 Jul;96(7):673-684. doi: 10.1007/s00109-018-1646-5. Epub 2018 May 28.

PMID:
29808244
3.

Large-scale patterning of living colloids for dynamic studies of neutrophil-microbe interactions.

Kim JJ, Reátegui E, Hopke A, Jalali F, Roushan M, Doyle PS, Irimia D.

Lab Chip. 2018 May 29;18(11):1514-1520. doi: 10.1039/c8lc00228b.

PMID:
29770423
4.

Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.

DeVos SL, Corjuc BT, Commins C, Dujardin S, Bannon RN, Corjuc D, Moore BD, Bennett RE, Jorfi M, Gonzales JA, Dooley PM, Roe AD, Pitstick R, Irimia D, Frosch MP, Carlson GA, Hyman BT.

Brain. 2018 Jul 1;141(7):2194-2212. doi: 10.1093/brain/awy117.

PMID:
29733334
5.

Inflammation-on-a-Chip: Probing the Immune System Ex Vivo.

Irimia D, Wang X.

Trends Biotechnol. 2018 May 1. pii: S0167-7799(18)30095-7. doi: 10.1016/j.tibtech.2018.03.011. [Epub ahead of print] Review.

PMID:
29728272
6.

Neutrophil Chemotaxis in One Droplet of Blood Using Microfluidic Assays.

Wang X, Irimia D.

Methods Mol Biol. 2018;1749:351-360. doi: 10.1007/978-1-4939-7701-7_25.

7.

Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease.

Jorfi M, D'Avanzo C, Tanzi RE, Kim DY, Irimia D.

Sci Rep. 2018 Feb 5;8(1):2450. doi: 10.1038/s41598-018-20436-8.

8.

Convergent and Divergent Migratory Patterns of Human Neutrophils inside Microfluidic Mazes.

Boneschansker L, Jorgensen J, Ellett F, Briscoe DM, Irimia D.

Sci Rep. 2018 Jan 30;8(1):1887. doi: 10.1038/s41598-018-20060-6.

9.

Microstructured Devices for Optimized Microinjection and Imaging of Zebrafish Larvae.

Ellett F, Irimia D.

J Vis Exp. 2017 Dec 8;(130). doi: 10.3791/56498.

10.

Brain-Computer Interfaces With Multi-Sensory Feedback for Stroke Rehabilitation: A Case Study.

Irimia DC, Cho W, Ortner R, Allison BZ, Ignat BE, Edlinger G, Guger C.

Artif Organs. 2017 Nov;41(11):E178-E184. doi: 10.1111/aor.13054.

PMID:
29148137
11.

A highly-occupied, single-cell trapping microarray for determination of cell membrane permeability.

Weng L, Ellett F, Edd J, Wong KHK, Uygun K, Irimia D, Stott SL, Toner M.

Lab Chip. 2017 Nov 21;17(23):4077-4088. doi: 10.1039/c7lc00883j.

PMID:
29068447
12.

Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming.

Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J, Elliott H, Irimia D.

Nat Biomed Eng. 2017;1. pii: 0094. doi: 10.1038/s41551-017-0094. Epub 2017 Jun 30.

13.

Resolvin D2 Limits Secondary Tissue Necrosis After Burn Wounds in Rats.

Inoue Y, Liu YM, Otawara M, Chico Calero I, Stephanie Nam A, Yu YM, Chang P, Butler KL, Nazarian RM, Goverman J, Vakoc BJ, Irimia D.

J Burn Care Res. 2018 Apr 20;39(3):423-432. doi: 10.1097/BCR.0000000000000617.

PMID:
28877131
14.

Neutrophil chemotaxis and transcriptomics in term and preterm neonates.

Raymond SL, Mathias BJ, Murphy TJ, Rincon JC, López MC, Ungaro R, Ellett F, Jorgensen J, Wynn JL, Baker HV, Moldawer LL, Irimia D, Larson SD.

Transl Res. 2017 Dec;190:4-15. doi: 10.1016/j.trsl.2017.08.003. Epub 2017 Sep 1.

PMID:
28873345
15.

Three-Dimensional Models of the Human Brain Development and Diseases.

Jorfi M, D'Avanzo C, Kim DY, Irimia D.

Adv Healthc Mater. 2018 Jan;7(1). doi: 10.1002/adhm.201700723. Epub 2017 Aug 28. Review.

16.

Rapid antibiotic sensitivity testing in microwell arrays.

Jalali F, Ellett F, Irimia D.

Technology (Singap World Sci). 2017 Jun;5(2):107-114. doi: 10.1142/S2339547817500030. Epub 2017 May 16.

17.

Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions.

Sandlin RD, Wong KHK, Boneschansker L, Carey TR, Miller KL, Rose G, Haber DA, Maheswaran S, Irimia D, Stott SL, Toner M.

Sci Rep. 2017 Jul 18;7(1):5658. doi: 10.1038/s41598-017-05978-7.

18.

Temporal gradients limit the accumulation of neutrophils towards sources of chemoattractant.

Chandrasekaran A, Ellett F, Jorgensen J, Irimia D.

Microsyst Nanoeng. 2017;3. pii: 16067. doi: 10.1038/micronano.2016.67. Epub 2017 Jan 2.

19.

recoveriX: a new BCI-based technology for persons with stroke.

Irimia D, Sabathiel N, Ortner R, Poboroniuc M, Coon W, Allison BZ, Guger C.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1504-1507. doi: 10.1109/EMBC.2016.7590995.

PMID:
28268612
20.

The Arp2/3 inhibitory protein Arpin is dispensable for chemotaxis.

Dang I, Linkner J, Yan J, Irimia D, Faix J, Gautreau A.

Biol Cell. 2017 Apr;109(4):162-166. doi: 10.1111/boc.201600064. Epub 2017 Mar 7. Review.

21.

Microstructured Surface Arrays for Injection of Zebrafish Larvae.

Ellett F, Irimia D.

Zebrafish. 2017 Apr;14(2):140-145. doi: 10.1089/zeb.2016.1402. Epub 2017 Feb 2.

22.

Neutrophil Interactions Stimulate Evasive Hyphal Branching by Aspergillus fumigatus.

Ellett F, Jorgensen J, Frydman GH, Jones CN, Irimia D.

PLoS Pathog. 2017 Jan 11;13(1):e1006154. doi: 10.1371/journal.ppat.1006154. eCollection 2017 Jan.

23.

Paired Associative Stimulation Using Brain-Computer Interfaces for Stroke Rehabilitation: A Pilot Study.

Cho W, Sabathiel N, Ortner R, Lechner A, Irimia DC, Allison BZ, Edlinger G, Guger C.

Eur J Transl Myol. 2016 Jun 6;26(3):6132. eCollection 2016 Jun 13.

24.

Porous microwells for geometry-selective, large-scale microparticle arrays.

Kim JJ, Bong KW, Reátegui E, Irimia D, Doyle PS.

Nat Mater. 2017 Jan;16(1):139-146. doi: 10.1038/nmat4747. Epub 2016 Sep 5.

25.

Technical Advance: Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay.

Frydman GH, Le A, Ellett F, Jorgensen J, Fox JG, Tompkins RG, Irimia D.

J Leukoc Biol. 2017 Mar;101(3):797-806. doi: 10.1189/jlb.1TA1115-517RR. Epub 2016 Sep 14.

26.

Netrin-1 Augments Chemokinesis in CD4+ T Cells In Vitro and Elicits a Proinflammatory Response In Vivo.

Boneschansker L, Nakayama H, Eisenga M, Wedel J, Klagsbrun M, Irimia D, Briscoe DM.

J Immunol. 2016 Aug 15;197(4):1389-98. doi: 10.4049/jimmunol.1502432. Epub 2016 Jul 18.

27.

A Worldwide Competition to Compare the Speed and Chemotactic Accuracy of Neutrophil-Like Cells.

Skoge M, Wong E, Hamza B, Bae A, Martel J, Kataria R, Keizer-Gunnink I, Kortholt A, Van Haastert PJ, Charras G, Janetopoulos C, Irimia D.

PLoS One. 2016 Jun 22;11(6):e0154491. doi: 10.1371/journal.pone.0154491. eCollection 2016.

28.

Big insights from small volumes: deciphering complex leukocyte behaviors using microfluidics.

Irimia D, Ellett F.

J Leukoc Biol. 2016 Aug;100(2):291-304. doi: 10.1189/jlb.5RU0216-056R. Epub 2016 May 18. Review.

29.

Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis.

Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN, Perretti M.

JCI Insight. 2016 Apr 21;1(5):e85922.

30.

The Role of Physical Stabilization in Whole Blood Preservation.

Wong KH, Sandlin RD, Carey TR, Miller KL, Shank AT, Oklu R, Maheswaran S, Haber DA, Irimia D, Stott SL, Toner M.

Sci Rep. 2016 Feb 15;6:21023. doi: 10.1038/srep21023.

31.

Microfluidic assay for precise measurements of mouse, rat, and human neutrophil chemotaxis in whole-blood droplets.

Jones CN, Hoang AN, Martel JM, Dimisko L, Mikkola A, Inoue Y, Kuriyama N, Yamada M, Hamza B, Kaneki M, Warren HS, Brown DE, Irimia D.

J Leukoc Biol. 2016 Jul;100(1):241-7. doi: 10.1189/jlb.5TA0715-310RR. Epub 2016 Jan 27.

PMID:
26819316
32.

Capillary plexuses are vulnerable to neutrophil extracellular traps.

Boneschansker L, Inoue Y, Oklu R, Irimia D.

Integr Biol (Camb). 2016 Feb;8(2):149-55. doi: 10.1039/c5ib00265f. Epub 2016 Jan 22.

33.

Directional memory arises from long-lived cytoskeletal asymmetries in polarized chemotactic cells.

Prentice-Mott HV, Meroz Y, Carlson A, Levine MA, Davidson MW, Irimia D, Charras GT, Mahadevan L, Shah JV.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1267-72. doi: 10.1073/pnas.1513289113. Epub 2016 Jan 13.

34.

Synthesis of Cell-Adhesive Anisotropic Multifunctional Particles by Stop Flow Lithography and Streptavidin-Biotin Interactions.

Bong KW, Kim JJ, Cho H, Lim E, Doyle PS, Irimia D.

Langmuir. 2015 Dec 8;31(48):13165-71. doi: 10.1021/acs.langmuir.5b03501. Epub 2015 Nov 25.

35.

Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.

Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D.

Crit Care Med. 2016 May;44(5):e241-52. doi: 10.1097/CCM.0000000000001397.

36.

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology.

Cho H, Seo JH, Wong KH, Terasaki Y, Park J, Bong K, Arai K, Lo EH, Irimia D.

Sci Rep. 2015 Oct 27;5:15222. doi: 10.1038/srep15222.

37.

Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients.

Orr SK, Butler KL, Hayden D, Tompkins RG, Serhan CN, Irimia D.

Crit Care Med. 2015 Dec;43(12):2642-50. doi: 10.1097/CCM.0000000000001312.

38.

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.

Takeda S, Wegmann S, Cho H, DeVos SL, Commins C, Roe AD, Nicholls SB, Carlson GA, Pitstick R, Nobuhara CK, Costantino I, Frosch MP, Müller DJ, Irimia D, Hyman BT.

Nat Commun. 2015 Oct 13;6:8490. doi: 10.1038/ncomms9490.

39.

Microfluidic mazes to characterize T-cell exploration patterns following activation in vitro.

Jain NG, Wong EA, Aranyosi AJ, Boneschansker L, Markmann JF, Briscoe DM, Irimia D.

Integr Biol (Camb). 2015 Nov;7(11):1423-31. doi: 10.1039/c5ib00146c.

40.

Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus.

Jones CN, Dimisko L, Forrest K, Judice K, Poznansky MC, Markmann JF, Vyas JM, Irimia D.

J Infect Dis. 2016 Feb 1;213(3):465-75. doi: 10.1093/infdis/jiv419. Epub 2015 Aug 12.

41.

Fast sorting of CD4+ T cells from whole blood using glass microbubbles.

Hsu CH, Chen C, Irimia D, Toner M.

Technology (Singap World Sci). 2015 Mar;3(1):38-44.

42.

Whole blood human neutrophil trafficking in a microfluidic model of infection and inflammation.

Hamza B, Irimia D.

Lab Chip. 2015 Jun 21;15(12):2625-33. doi: 10.1039/c5lc00245a.

43.

"Universal" vitrification of cells by ultra-fast cooling.

Heo YS, Nagrath S, Moore AL, Zeinali M, Irimia D, Stott SL, Toth TL, Toner M.

Technology (Singap World Sci). 2015 Mar;3(1):64-71.

44.

Translational implications of endothelial cell dysfunction in association with chronic allograft rejection.

Bruneau S, Wedel J, Fakhouri F, Nakayama H, Boneschansker L, Irimia D, Daly KP, Briscoe DM.

Pediatr Nephrol. 2016 Jan;31(1):41-51. doi: 10.1007/s00467-015-3094-6. Epub 2015 Apr 24. Review.

45.

Spontaneous neutrophil migration patterns during sepsis after major burns.

Jones CN, Moore M, Dimisko L, Alexander A, Ibrahim A, Hassell BA, Warren HS, Tompkins RG, Fagan SP, Irimia D.

PLoS One. 2014 Dec 9;9(12):e114509. doi: 10.1371/journal.pone.0114509. eCollection 2014.

46.

A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid β in the brain in a transgenic model of Alzheimer disease.

Hori Y, Takeda S, Cho H, Wegmann S, Shoup TM, Takahashi K, Irimia D, Elmaleh DR, Hyman BT, Hudry E.

J Biol Chem. 2015 Jan 23;290(4):1966-78. doi: 10.1074/jbc.M114.586602. Epub 2014 Dec 2.

47.

Stochastic variations of migration speed between cells in clonal populations.

Yan J, Irimia D.

Technology (Singap World Sci). 2014 Sep;2(3):185-188.

48.

Three-Dimensional Holographic Refractive-Index Measurement of Continuously Flowing Cells in a Microfluidic Channel.

Sung Y, Lue N, Hamza B, Martel J, Irimia D, Dasari RR, Choi W, Yaqoob Z, So P.

Phys Rev Appl. 2014 Feb 27;1. pii: 014002.

49.

A neutrophil treadmill to decouple spatial and temporal signals during chemotaxis.

Aranyosi AJ, Wong EA, Irimia D.

Lab Chip. 2015 Jan 21;15(2):549-556. doi: 10.1039/c4lc00970c.

50.

New methods for investigation of neuronal migration in embryonic brain explants.

Nery FC, da Hora CC, Yaqub U, Zhang X, McCarthy DM, Bhide PG, Irimia D, Breakefield XO.

J Neurosci Methods. 2015 Jan 15;239:80-4. doi: 10.1016/j.jneumeth.2014.09.028. Epub 2014 Oct 5.

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