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Radiologically occult metastatic pancreatic cancer: how can we avoid unbeneficial resection?

Oba A, Inoue Y, Ono Y, Irie S, Sato T, Mise Y, Ito H, Takahashi Y, Saiura A.

Langenbecks Arch Surg. 2019 Nov 28. doi: 10.1007/s00423-019-01846-2. [Epub ahead of print]


International expert consensus statement about methods and indications for keyhole microneurosurgery from International Society on Minimally Invasive Neurosurgery.

Lan Q, Sughrue M, Hopf NJ, Mori K, Park J, Andrade-Barazarte H, Balamurugan M, Cenzato M, Broggi G, Kang D, Kikuta K, Zhao Y, Zhang H, Irie S, Li Y, Liew BS, Kato Y.

Neurosurg Rev. 2019 Nov 21. doi: 10.1007/s10143-019-01188-z. [Epub ahead of print] Review. No abstract available.


Elucidation of N 1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters.

Miyake T, Mizuno T, Takehara I, Mochizuki T, Kimura M, Matsuki S, Irie S, Watanabe N, Kato Y, Ieiri I, Maeda K, Ando O, Kusuhara H.

Drug Metab Dispos. 2019 Nov;47(11):1270-1280. doi: 10.1124/dmd.119.087262. Epub 2019 Sep 11.


Nonischemic or Ischemic Laparoscopic Partial Nephrectomy Using a Newly Developed Hybrid Energy Device in a Porcine Model.

Tanaka M, Irie S, Nakagawa K, Nishimatsu H, Inokuchi J, Eto M.

J Endourol. 2019 Oct 9. doi: 10.1089/end.2019.0435. [Epub ahead of print]


Severe hypertriglyceridemia in a subject with disturbed life style and poor glycemic control without recurrence of acute pancreatitis: a case report.

Irie S, Anno T, Kawasaki F, Shigemoto R, Nakanishi S, Kaku K, Kaneto H.

BMC Endocr Disord. 2019 Aug 30;19(1):92. doi: 10.1186/s12902-019-0425-9.


Adhesion Control of Branched Catecholic Polymers by Acid Stimulation.

Kohri M, Yamazaki S, Irie S, Teramoto N, Taniguchi T, Kishikawa K.

ACS Omega. 2018 Dec 5;3(12):16626-16632. doi: 10.1021/acsomega.8b02768. eCollection 2018 Dec 31.


Dramatic Improvement of Glycemic Control by Promptly Starting Steroid Therapy at an Early Stage of Autoimmune Pancreatitis in a Subject with Type 2 Diabetes.

Irie S, Anno T, Uji E, Nakamura J, Kawasaki F, Kawamoto H, Kaku K, Kaneto H.

Intern Med. 2019 Dec 1;58(23):3427-3431. doi: 10.2169/internalmedicine.3198-19. Epub 2019 Jul 31.


Marked elevation of plasma procalcitonin levels in patients with diabetic ketoacidosis: A possible useful diagnostic biomarker.

Anno T, Shigemoto R, Kawasaki F, Irie S, Miyashita N, Kaku K, Kaneto H.

Diabetes Metab. 2019 Jun 4. pii: S1262-3636(19)30089-8. doi: 10.1016/j.diabet.2019.05.006. [Epub ahead of print] No abstract available.


Role of Computed Tomography Volumetry in Preoperative Donor Renal Function Evaluation of Living Related Kidney Transplantation.

Nakamura N, Aoyagi C, Matsuzaki H, Furuya R, Irie S, Matsuoka H, Tanaka M.

Transplant Proc. 2019 Jun;51(5):1314-1316. doi: 10.1016/j.transproceed.2019.01.130. Epub 2019 May 2.


PET imaging of 11C-labeled coenzyme Q10: Comparison of biodistribution between [11C]ubiquinol-10 and [11C]ubiquinone-10.

Watanabe K, Nozaki S, Goto M, Kaneko KI, Hayashinaka E, Irie S, Nishiyama A, Kasai K, Fujii K, Wada Y, Mizuno K, Mizuseki K, Doi H, Watanabe Y.

Biochem Biophys Res Commun. 2019 May 7;512(3):611-615. doi: 10.1016/j.bbrc.2019.03.073. Epub 2019 Mar 23.


Acute exacerbation of chronic osteomyelitis triggered by aggravation of type 2 diabetes mellitus: a case report.

Irie S, Anno T, Kawasaki F, Shigemoto R, Kaneto H, Kaku K, Okimoto N.

J Med Case Rep. 2019 Jan 7;13(1):7. doi: 10.1186/s13256-018-1954-y.


Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers.

Mori D, Kashihara Y, Yoshikado T, Kimura M, Hirota T, Matsuki S, Maeda K, Irie S, Ieiri I, Sugiyama Y, Kusuhara H.

Drug Metab Pharmacokinet. 2019 Feb;34(1):78-86. doi: 10.1016/j.dmpk.2018.09.003. Epub 2018 Sep 20.


Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation.

Kashihara Y, Terao Y, Yoda K, Hirota T, Kubota T, Kimura M, Matsuki S, Hirakawa M, Irie S, Ieiri I.

Eur J Clin Pharmacol. 2019 Mar;75(3):351-361. doi: 10.1007/s00228-018-2568-4. Epub 2018 Oct 31.


Pharmacokinetics of Tenofovir Alafenamide, Tenofovir, and Emtricitabine Following Administration of Coformulated Emtricitabine/Tenofovir Alafenamide in Healthy Japanese Subjects.

Yamada H, Yonemura T, Nemoto T, Ninomiya N, Irie S.

Clin Pharmacol Drug Dev. 2019 May;8(4):511-520. doi: 10.1002/cpdd.623. Epub 2018 Oct 16.


Treatment Recommendations for Urological Symptoms in Cancer Patients: Clinical Guidelines from the Japanese Society for Palliative Medicine.

Tsushima T, Miura T, Hachiya T, Nakamura I, Yamato T, Kishida T, Tanaka Y, Irie S, Meguro N, Kawahara T, Nakajima N.

J Palliat Med. 2019 Jan;22(1):54-61. doi: 10.1089/jpm.2018.0116. Epub 2018 Oct 5.


Lessons Learned in Providing Claims-Based Data to Participants in Health Care Innovation Models.

Cohen MF, Irie SM, Russo CA, Pav V, O'Connor SL, Wensky SG.

Am J Med Qual. 2019 May/Jun;34(3):234-242. doi: 10.1177/1062860618798715. Epub 2018 Sep 8.


[Azacitidine for Therapy-Related Myelodysplastic Syndrome Following Oxaliplatin (L-OHP)Therapy for Metastatic Rectal Cancer].

Matsui T, Sakamoto N, Doi A, Fujii T, Ohno N, Sahara N, Irie S.

Gan To Kagaku Ryoho. 2018 Aug;45(8):1201-1203. Japanese.


Safety, Tolerability, and Pharmacokinetics of NK-104-NP.

Nakano K, Matoba T, Koga JI, Kashihara Y, Fukae M, Ieiri I, Shiramoto M, Irie S, Kishimoto J, Todaka K, Egashira K.

Int Heart J. 2018 Sep 26;59(5):1015-1025. doi: 10.1536/ihj.17-555. Epub 2018 Aug 29.


Hand Dexterity Impairment in Patients with Cervical Myelopathy: A New Quantitative Assessment Using a Natural Prehension Movement.

Omori M, Shibuya S, Nakajima T, Endoh T, Suzuki S, Irie S, Ariyasu R, Unenaka S, Sano H, Igarashi K, Ichimura S, Ohki Y.

Behav Neurol. 2018 Jul 4;2018:5138234. doi: 10.1155/2018/5138234. eCollection 2018.


Prior vaccinations improve immunogenicity of inactivated influenza vaccine in young children aged 6 months to 3 years: A cohort study.

Ito K, Mugitani A, Irie S, Ishibashi M, Takasaki Y, Shindo S, Yokoyama T, Yamashita Y, Shibao K, Koyanagi H, Fukushima W, Ohfuji S, Maeda A, Kase T, Hirota Y.

Medicine (Baltimore). 2018 Jul;97(29):e11551. doi: 10.1097/MD.0000000000011551.


There is a Close Association Between the Recovery of Liver Injury and Glycemic Control after SGLT2 Inhibitor Treatment in Japanese Subjects with Type 2 Diabetes: A Retrospective Clinical Study.

Kinoshita T, Shimoda M, Sanada J, Fushimi Y, Hirata Y, Irie S, Obata A, Kimura T, Hirukawa H, Kohara K, Tatsumi F, Kamei S, Nakanishi S, Mune T, Kaku K, Kaneto H.

Diabetes Ther. 2018 Aug;9(4):1569-1580. doi: 10.1007/s13300-018-0447-8. Epub 2018 Jun 21.


Efficacy and Safety of Switching from Insulin Glargine 100 U/mL to the Same Dose of Glargine 300 U/mL in Japanese Type 1 and 2 Diabetes Patients: A Retrospective Analysis.

Nakanishi S, Iwamoto M, Kamei S, Hirukawa H, Shimoda M, Tatsumi F, Kohara K, Obata A, Kimura T, Kinoshita T, Irie S, Sanada J, Fushimi Y, Nishioka M, Mizoguchi A, Kameyama M, Mune T, Kaku K, Kaneto H.

Intern Med. 2018;57(10):1381-1389. doi: 10.2169/internalmedicine.9334-17. Epub 2018 May 15.


G protein-coupled receptor 119 agonist DS-8500a effects on pancreatic β-cells in Japanese type 2 diabetes mellitus patients.

Watada H, Shiramoto M, Irie S, Terauchi Y, Yamada Y, Shiosakai K, Myobatake Y, Taguchi T.

J Diabetes Investig. 2019 Jan;10(1):84-93. doi: 10.1111/jdi.12849. Epub 2018 May 4.


A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography.

Kaneko K, Tanaka M, Ishii A, Katayama Y, Nakaoka T, Irie S, Kawahata H, Yamanaga T, Wada Y, Miyake T, Toshimoto K, Maeda K, Cui Y, Enomoto M, Kawamura E, Kawada N, Kawabe J, Shiomi S, Kusuhara H, Sugiyama Y, Watanabe Y.

Drug Metab Dispos. 2018 May;46(5):719-728. doi: 10.1124/dmd.118.080408. Epub 2018 Mar 19.


A Randomized Trial Investigating the Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Semaglutide Once-Weekly in Healthy Male Japanese and Caucasian Subjects.

Ikushima I, Jensen L, Flint A, Nishida T, Zacho J, Irie S.

Adv Ther. 2018 Apr;35(4):531-544. doi: 10.1007/s12325-018-0677-1. Epub 2018 Mar 13.


Saibokuto as a Possible Therapy for Type B Insulin Resistance Syndrome: The Disappearance of Anti-insulin Receptor Antibody and a Marked Amelioration of Glycemic Control by Saibokuto Treatment.

Kawasaki F, Anno T, Takai M, Irie S, Kaneto H, Kaku K, Okimoto N.

Intern Med. 2018 Aug 15;57(16):2359-2363. doi: 10.2169/internalmedicine.0523-17. Epub 2018 Mar 9.


Long-lasting memory of cellular immunity in a chronic myeloid leukemia patient maintains molecular response 5 after cessation of dasatinib.

Jo T, Noguchi K, Hayashi S, Irie S, Hayase R, Shioya H, Kaneko Y, Horio K, Taguchi J.

Oncol Lett. 2018 Mar;15(3):2935-2938. doi: 10.3892/ol.2017.7720. Epub 2017 Dec 29.


Idiopathic and Chronic Epidural Hematoma in the Lumbar Spine: A Case Report and Review of Literatures.

Okazaki T, Nakagawa H, Hayase H, Irie S, Inagaki T, Saito O, Yamashina M, Nagahiro S, Saito K.

Neurol Med Chir (Tokyo). 2018 Mar 15;58(3):138-144. doi: 10.2176/ Epub 2018 Feb 7. Review.


Coloring Technique of Magnetic Resonance Angiography for Superficial Temporal Artery to Middle Cerebral Artery Bypass Surgery.

Okazaki T, Irie S, Inagaki T, Saito O, Yamashina M, Hayase H, Nakagawa H, Nagahiro S, Saito K.

World Neurosurg. 2018 Apr;112:e113-e118. doi: 10.1016/j.wneu.2017.12.152. Epub 2018 Jan 31.


Effects of eugenol on respiratory burst generation in newborn rat brainstem-spinal cord preparations.

Kotani S, Irie S, Izumizaki M, Onimaru H.

Pflugers Arch. 2018 Feb;470(2):385-394. doi: 10.1007/s00424-017-2074-z. Epub 2017 Sep 29.


Non-clostridial gas gangrene in a patient with poorly controlled type 2 diabetes mellitus on hemodialysis.

Shigemoto R, Anno T, Kawasaki F, Irie S, Yamamoto M, Tokuoka S, Kaneto H, Kaku K, Okimoto N.

Acta Diabetol. 2018 Jan;55(1):99-101. doi: 10.1007/s00592-017-1038-2. Epub 2017 Sep 5. No abstract available.


Werner Syndrome and Diabetes Mellitus Accompanied by Adrenal Cortex Cancer.

Nishioka M, Kamei S, Kinoshita T, Sanada J, Fushimi Y, Irie S, Hirata Y, Tanabe A, Hirukawa H, Kimura T, Obata A, Tatsumi F, Kohara K, Shimoda M, Nakanishi S, Mune T, Kaku K, Kaneto H.

Intern Med. 2017;56(15):1987-1992. doi: 10.2169/internalmedicine.56.8231. Epub 2017 Aug 1.


Inadequate Triglyceride Management Worsens the Durability of Dipeptidyl Peptidase-4 Inhibitor in Subjects with Type 2 Diabetes Mellitus.

Shimoda M, Miyoshi-Takai M, Irie S, Tanabe A, Obata A, Okauchi S, Hirukawa H, Kimura T, Kohara K, Kamei S, Mune T, Kaku K, Kaneto H.

J Diabetes Res. 2017;2017:5856475. doi: 10.1155/2017/5856475. Epub 2017 May 25.


Hypoglycemic Coma Induced by the Use of Succinic Acid Cibenzoline in Frail Late-stage Elderly Subjects.

Hirata Y, Kamei S, Tatsumi F, Shimoda M, Tanabe A, Sanada J, Fushimi Y, Irie S, Mune T, Kaku K, Kaneto H.

Intern Med. 2017;56(12):1527-1529. doi: 10.2169/internalmedicine.56.8120. Epub 2017 Jun 15.


Immunogenicity study to investigate the interchangeability among three different types of polio vaccine: A cohort study in Japan.

Ohfuji S, Ito K, Ishibashi M, Shindo S, Takasaki Y, Yokoyama T, Yokoyama T, Yamashita Y, Shibao K, Nakano T, Tsuru T, Irie S, Hirota Y.

Medicine (Baltimore). 2017 Jun;96(23):e7073. doi: 10.1097/MD.0000000000007073.


Effects of a Nutritional Protein-Rich Drink on the Pharmacokinetics of Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Alafenamide, and Tenofovir Compared With a Standard Meal in Healthy Japanese Male Subjects.

Yamada H, Ikushima I, Nemoto T, Ishikawa T, Ninomiya N, Irie S.

Clin Pharmacol Drug Dev. 2018 Feb;7(2):132-142. doi: 10.1002/cpdd.365. Epub 2017 Jun 5.


Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide.

Miyake T, Mizuno T, Mochizuki T, Kimura M, Matsuki S, Irie S, Ieiri I, Maeda K, Kusuhara H.

J Pharm Sci. 2017 Sep;106(9):2542-2550. doi: 10.1016/j.xphs.2017.04.067. Epub 2017 May 4.


Vestibular stimulation-induced facilitation of cervical premotoneuronal systems in humans.

Suzuki S, Nakajima T, Irie S, Ariyasu R, Komiyama T, Ohki Y.

PLoS One. 2017 Apr 7;12(4):e0175131. doi: 10.1371/journal.pone.0175131. eCollection 2017.


Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP.

Kashihara Y, Ieiri I, Yoshikado T, Maeda K, Fukae M, Kimura M, Hirota T, Matsuki S, Irie S, Izumi N, Kusuhara H, Sugiyama Y.

J Pharm Sci. 2017 Sep;106(9):2688-2694. doi: 10.1016/j.xphs.2017.03.010. Epub 2017 Mar 18.


Experience of Quatro-Therapy With Everolimus to Minimize Calcineurin Inhibitor for Kidney Transplant Recipients.

Nakamura N, Miyazaki T, Matsuzaki H, Furuya R, Miyajima S, Irie S, Matsuoka H, Tanaka M.

Transplant Proc. 2017 Jan - Feb;49(1):32-36. doi: 10.1016/j.transproceed.2016.11.005.


Noninfectious prevertebral soft-tissue inflammation and hematoma eliciting swelling after anterior cervical discectomy and fusion.

Yagi K, Nakagawa H, Okazaki T, Irie S, Inagaki T, Saito O, Nagahiro S, Saito K.

J Neurosurg Spine. 2017 Apr;26(4):459-465. doi: 10.3171/2016.9.SPINE16520. Epub 2017 Jan 13.


Genetic polymorphisms of enzyme proteins and transporters related to methotrexate response and pharmacokinetics in a Japanese population.

Hashiguchi M, Shimizu M, Hakamata J, Tsuru T, Tanaka T, Suzaki M, Miyawaki K, Chiyoda T, Takeuchi O, Hiratsuka J, Irie S, Maruyama J, Mochizuki M.

J Pharm Health Care Sci. 2016 Dec 9;2:35. eCollection 2016.


Effects of a TRPV1 agonist capsaicin on respiratory rhythm generation in brainstem-spinal cord preparation from newborn rats.

Tani M, Kotani S, Hayakawa C, Lin ST, Irie S, Ikeda K, Kawakami K, Onimaru H.

Pflugers Arch. 2017 Feb;469(2):327-338. doi: 10.1007/s00424-016-1912-8. Epub 2016 Nov 29.


Dramatic mitigation of bone pain after phosphorus replacement therapy in a subject with FGF23-related hypophosphatemic osteomalacia.

Tatsumi F, Horiya M, Tanabe A, Nishioka M, Fushimi Y, Sanada J, Hirata Y, Irie S, Kinoshita T, Kamei S, Shimoda M, Mune T, Kaku K, Kaneto H.

Springerplus. 2016 Nov 2;5(1):1904. eCollection 2016.


Effects of DPP-4 inhibitor linagliptin and GLP-1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: A randomized, open-label, 2-arm parallel comparative, exploratory trial.

Yabe D, Eto T, Shiramoto M, Irie S, Murotani K, Seino Y, Kuwata H, Kurose T, Seino S, Ahrén B, Seino Y.

Diabetes Obes Metab. 2017 Mar;19(3):442-447. doi: 10.1111/dom.12817. Epub 2016 Nov 29.


Association of GA/HbA1c ratio and cognitive impairment in subjects with type 2 diabetes mellitus.

Kinoshita T, Shimoda M, Sanada J, Fushimi Y, Hirata Y, Irie S, Tanabe A, Obata A, Kimura T, Hirukawa H, Kohara K, Tatsumi F, Kamei S, Nakanishi S, Mune T, Kaku K, Kaneto H.

J Diabetes Complications. 2016 Nov - Dec;30(8):1452-1455. doi: 10.1016/j.jdiacomp.2016.08.008. Epub 2016 Aug 12.


Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines.

Gotanda K, Hirota T, Saito J, Fukae M, Egashira Y, Izumi N, Deguchi M, Kimura M, Matsuki S, Irie S, Ieiri I.

Sci Rep. 2016 Aug 30;6:32299. doi: 10.1038/srep32299.


Clarification of the Mechanism of Clopidogrel-Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information.

Kim SJ, Yoshikado T, Ieiri I, Maeda K, Kimura M, Irie S, Kusuhara H, Sugiyama Y.

Drug Metab Dispos. 2016 Oct;44(10):1622-32. doi: 10.1124/dmd.116.070276. Epub 2016 Jul 25.


Hamman's syndrome triggered by the onset of type 1 diabetes mellitus accompanied by diabetic ketoacidosis.

Kamei S, Kaneto H, Tanabe A, Shigemoto R, Irie S, Hirata Y, Takai M, Kohara K, Shimoda M, Mune T, Kaku K.

Acta Diabetol. 2016 Dec;53(6):1067-1068. doi: 10.1007/s00592-016-0871-z. Epub 2016 Jun 13. No abstract available.


Preliminary study for predicting better methotrexate efficacy in Japanese patients with rheumatoid arthritis.

Hashiguchi M, Tsuru T, Miyawaki K, Suzaki M, Hakamata J, Shimizu M, Irie S, Mochizuki M.

J Pharm Health Care Sci. 2016 Jun 7;2:13. doi: 10.1186/s40780-016-0047-6. eCollection 2016.

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