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Items: 20


PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells.

Ito K, Park SH, Katsyv I, Zhang W, De Angelis C, Schiff R, Irie HY.

NPJ Breast Cancer. 2017 Nov 17;3:45. doi: 10.1038/s41523-017-0047-1. eCollection 2017.


PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells.

Byerly J, Halstead-Nussloch G, Ito K, Katsyv I, Irie HY.

Breast Cancer Res. 2016 Sep 23;18(1):95. doi: 10.1186/s13058-016-0749-6.


EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer.

Katsyv I, Wang M, Song WM, Zhou X, Zhao Y, Park S, Zhu J, Zhang B, Irie HY.

Oncotarget. 2016 Oct 25;7(43):69592-69605. doi: 10.18632/oncotarget.11870.


PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation.

Ito K, Park SH, Nayak A, Byerly JH, Irie HY.

Cancer Res. 2016 Aug 1;76(15):4406-17. doi: 10.1158/0008-5472.CAN-15-3445. Epub 2016 Jun 14.


Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers.

Lee E, Ito K, Zhao Y, Schadt EE, Irie HY, Zhu J.

Bioinformatics. 2016 Jan 1;32(1):96-105. doi: 10.1093/bioinformatics/btv531. Epub 2015 Sep 10.


Analysis of ALK gene in 133 patients with breast cancer revealed polysomy of chromosome 2 and no ALK amplification.

Hanna MG, Najfeld V, Irie HY, Tripodi J, Nayak A.

Springerplus. 2015 Aug 21;4:439. doi: 10.1186/s40064-015-1235-9. eCollection 2015.


PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.

Park SH, Ito K, Olcott W, Katsyv I, Halstead-Nussloch G, Irie HY.

Breast Cancer Res. 2015 Jun 19;17:86. doi: 10.1186/s13058-015-0594-z.


The Proteomic Landscape of Triple-Negative Breast Cancer.

Lawrence RT, Perez EM, Hernández D, Miller CP, Haas KM, Irie HY, Lee SI, Blau CA, Villén J.

Cell Rep. 2015 May 12;11(6):990. doi: 10.1016/j.celrep.2015.04.059. Epub 2015 May 12. No abstract available.


The proteomic landscape of triple-negative breast cancer.

Lawrence RT, Perez EM, Hernández D, Miller CP, Haas KM, Irie HY, Lee SI, Blau CA, Villén J.

Cell Rep. 2015 Apr 28;11(4):630-44. doi: 10.1016/j.celrep.2015.03.050. Epub 2015 Apr 16. Erratum in: Cell Rep. 2015 May 12;11(6):990.


Expression of IGF1R in normal breast tissue and subsequent risk of breast cancer.

Tamimi RM, Colditz GA, Wang Y, Collins LC, Hu R, Rosner B, Irie HY, Connolly JL, Schnitt SJ.

Breast Cancer Res Treat. 2011 Jul;128(1):243-50. doi: 10.1007/s10549-010-1313-1. Epub 2011 Jan 1.


PTK6 regulates IGF-1-induced anchorage-independent survival.

Irie HY, Shrestha Y, Selfors LM, Frye F, Iida N, Wang Z, Zou L, Yao J, Lu Y, Epstein CB, Natesan S, Richardson AL, Polyak K, Mills GB, Hahn WC, Brugge JS.

PLoS One. 2010 Jul 23;5(7):e11729. doi: 10.1371/journal.pone.0011729.


Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.

Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS.

Nature. 2009 Sep 3;461(7260):109-13. doi: 10.1038/nature08268. Epub 2009 Aug 19.


A CD8/Lck transgene is able to drive thymocyte differentiation.

Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ.

J Immunol. 2006 Nov 1;177(9):6007-17.


Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition.

Irie HY, Pearline RV, Grueneberg D, Hsia M, Ravichandran P, Kothari N, Natesan S, Brugge JS.

J Cell Biol. 2005 Dec 19;171(6):1023-34.


Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells.

Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, Cantley LC, Brugge JS.

Cancer Res. 2005 Dec 1;65(23):10992-1000.


Unusual problems in breast cancer and a rare lung cancer case. Case 4. Primary lymphoepithelioma-like carcinoma of the lung.

Irie HY, Jaklitsch MT, Shaffer K, Weinstein M, Salgia R.

J Clin Oncol. 2003 Jun 1;21(11):2220-2. No abstract available.


Antigen-induced unresponsiveness results in altered T cell signaling.

McKay DB, Irie HY, Hollander G, Ferrara JL, Strom TB, Li Y, Burakoff SJ.

J Immunol. 1999 Dec 15;163(12):6455-61.


The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

Irie HY, Mong MS, Itano A, Crooks ME, Littman DR, Burakoff SJ, Robey E.

J Immunol. 1998 Jul 1;161(1):183-91.


Coreceptors and adapter proteins in T-cell signaling.

Ravichandran KS, Pratt JC, Sawasdikosol S, Irie HY, Burakoff SJ.

Ann N Y Acad Sci. 1995 Sep 7;766:117-33. Review. No abstract available.


CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity.

Irie HY, Ravichandran KS, Burakoff SJ.

J Exp Med. 1995 Apr 1;181(4):1267-73.

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