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Items: 8


Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.

English WR, Ireland-Zecchini H, Baker AH, Littlewood TD, Bennett MR, Murphy G.

PLoS One. 2018 Apr 4;13(4):e0195116. doi: 10.1371/journal.pone.0195116. eCollection 2018.


Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.

Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, Borlido J, Stark R, Ireland-Zecchini H, Rao R, Scott H, Boren J, Massie C, Asim M, Brindle K, Griffiths J, Frezza C, Neal DE, Mills IG.

EMBO J. 2014 Jun 17;33(12):1365-82. doi: 10.15252/embj.201386874. Epub 2014 May 16.


Dual-sugar imaging using isonitrile and azido-based click chemistries.

Wainman YA, Neves AA, Stairs S, Stöckmann H, Ireland-Zecchini H, Brindle KM, Leeper FJ.

Org Biomol Chem. 2013 Nov 14;11(42):7297-300. doi: 10.1039/c3ob41805g.


Metabolic glycan imaging by isonitrile-tetrazine click chemistry.

Stairs S, Neves AA, Stöckmann H, Wainman YA, Ireland-Zecchini H, Brindle KM, Leeper FJ.

Chembiochem. 2013 Jun 17;14(9):1063-7. doi: 10.1002/cbic.201300130. Epub 2013 May 13.


Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells.

Stöckmann H, Neves AA, Stairs S, Ireland-Zecchini H, Brindle KM, Leeper FJ.

Chem Sci. 2011 May;2(5):932-936.


Imaging sialylated tumor cell glycans in vivo.

Neves AA, Stöckmann H, Harmston RR, Pryor HJ, Alam IS, Ireland-Zecchini H, Lewis DY, Lyons SK, Leeper FJ, Brindle KM.

FASEB J. 2011 Aug;25(8):2528-37. doi: 10.1096/fj.10-178590. Epub 2011 Apr 14.


Characterization of a heat resistant beta-glucosidase as a new reporter in cells and mice.

McCutcheon SC, Jones K, Cumming SA, Kemp R, Ireland-Zecchini H, Saunders JC, Houghton CA, Howard LA, Winton DJ.

BMC Biol. 2010 Jun 22;8:89. doi: 10.1186/1741-7007-8-89.


Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.

Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Rückert F, Grützmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-Donahue C, Griffiths J, Tuveson DA.

Science. 2009 Jun 12;324(5933):1457-61. doi: 10.1126/science.1171362. Epub 2009 May 21.

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