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Items: 1 to 50 of 168

1.

In vivo effect of bevacizumab-loaded albumin nanoparticles in the treatment of corneal neovascularization.

Luis de Redín I, Boiero C, Recalde S, Agüeros M, Allemandi D, Llabot JM, García-Layana A, Irache JM.

Exp Eye Res. 2019 Jun 19:107697. doi: 10.1016/j.exer.2019.107697. [Epub ahead of print]

PMID:
31228461
2.

Mannosylated Nanoparticles for Oral Immunotherapy in a Murine Model of Peanut Allergy.

Brotons-Canto A, Gamazo C, Martín-Arbella N, Abdulkarim M, Gumbleton M, Quincoces G, Peñuelas I, Irache JM.

J Pharm Sci. 2019 Mar 6. pii: S0022-3549(19)30140-6. doi: 10.1016/j.xphs.2019.02.022. [Epub ahead of print]

PMID:
30849462
3.

Understanding the basis of transcutaneous vaccine delivery.

Gamazo C, Pastor Y, Larrañeta E, Berzosa M, Irache JM, Donnelly RF.

Ther Deliv. 2019 Jan;10(1):63-80. doi: 10.4155/tde-2018-0054.

PMID:
30730825
4.

The effect of thiamine-coating nanoparticles on their biodistribution and fate following oral administration.

Inchaurraga L, Martínez-López AL, Cattoz B, Griffiths PC, Wilcox M, Pearson JP, Quincoces G, Peñuelas I, Martin-Arbella N, Irache JM.

Eur J Pharm Sci. 2019 Feb 1;128:81-90. doi: 10.1016/j.ejps.2018.11.025. Epub 2018 Nov 23.

PMID:
30472222
5.

Towards a subunit vaccine from a Shigella flexneri ΔtolR mutant.

Pastor Y, Camacho AI, Zúñiga-Ripa A, Merchán A, Rosas P, Irache JM, Gamazo C.

Vaccine. 2018 Nov 26;36(49):7509-7519. doi: 10.1016/j.vaccine.2018.10.066. Epub 2018 Oct 24.

PMID:
30420041
6.

Increased Oral Bioavailability of Resveratrol by Its Encapsulation in Casein Nanoparticles.

Peñalva R, Morales J, González-Navarro CJ, Larrañeta E, Quincoces G, Peñuelas I, Irache JM.

Int J Mol Sci. 2018 Sep 18;19(9). pii: E2816. doi: 10.3390/ijms19092816.

7.

Combination of paromomycin plus human anti-TNF-α antibodies to control the local inflammatory response in BALB/ mice with cutaneous leishmaniasis lesions.

Schwartz J, Moreno E, Calvo A, Blanco L, Fernández-Rubio C, Sanmartín C, Nguewa P, Irache JM, Larrea E, Espuelas S.

J Dermatol Sci. 2018 Oct;92(1):78-88. doi: 10.1016/j.jdermsci.2018.07.005. Epub 2018 Jul 17.

PMID:
30037731
8.

Cyclodextrin-grafted poly(anhydride) nanoparticles for oral glibenclamide administration. In vivo evaluation using C. elegans.

Lucio D, Martínez-Ohárriz MC, Gu Z, He Y, Aranaz P, Vizmanos JL, Irache JM.

Int J Pharm. 2018 Aug 25;547(1-2):97-105. doi: 10.1016/j.ijpharm.2018.05.064. Epub 2018 May 26.

PMID:
29842888
9.

Pegylated nanoparticles for the oral delivery of nimodipine: Pharmacokinetics and effect on the anxiety and cognition in mice.

Moreno LCGEAI, Solas M, Martínez-Ohárriz MC, Muñoz E, Santos-Magalhães NS, Ramirez MJ, Irache JM.

Int J Pharm. 2018 May 30;543(1-2):245-256. doi: 10.1016/j.ijpharm.2018.03.048. Epub 2018 Mar 28.

PMID:
29604372
10.

Pegylated poly(anhydride) nanoparticles for oral delivery of docetaxel.

Ruiz-Gatón L, Espuelas S, Larrañeta E, Reviakine I, Yate LA, Irache JM.

Eur J Pharm Sci. 2018 Jun 15;118:165-175. doi: 10.1016/j.ejps.2018.03.028. Epub 2018 Mar 26.

PMID:
29597043
11.

Human serum albumin nanoparticles for ocular delivery of bevacizumab.

Luis de Redín I, Boiero C, Martínez-Ohárriz MC, Agüeros M, Ramos R, Peñuelas I, Allemandi D, Llabot JM, Irache JM.

Int J Pharm. 2018 Apr 25;541(1-2):214-223. doi: 10.1016/j.ijpharm.2018.02.003. Epub 2018 Feb 24.

PMID:
29481946
12.

Poly(anhydride) nanoparticles containing cashew nut proteins can induce a strong Th1 and Treg immune response after oral administration.

Pereira MA, Rebouças JS, Ferraz-Carvalho RS, de Redín IL, Guerra PV, Gamazo C, Brodskyn CI, Irache JM, Santos-Magalhães NS.

Eur J Pharm Biopharm. 2018 Jun;127:51-60. doi: 10.1016/j.ejpb.2018.02.011. Epub 2018 Feb 8.

PMID:
29428795
13.

Evaluation of the treatment with resveratrol-loaded nanoparticles in intestinal injury model caused by ischemia and reperfusion.

Borges SC, Ferreira PEB, da Silva LM, de Paula Werner MF, Irache JM, Cavalcanti OA, Buttow NC.

Toxicology. 2018 Mar 1;396-397:13-22. doi: 10.1016/j.tox.2018.02.002. Epub 2018 Feb 7.

14.

Coencapsulation of cyclodextrins into poly(anhydride) nanoparticles to improve the oral administration of glibenclamide. A screening on C. elegans.

Lucio D, Martínez-Ohárriz MC, González-Navarro CJ, Navarro-Herrera D, González-Gaitano G, Radulescu A, Irache JM.

Colloids Surf B Biointerfaces. 2018 Mar 1;163:64-72. doi: 10.1016/j.colsurfb.2017.12.038. Epub 2017 Dec 21.

PMID:
29277019
15.

Maternal Vaccination. Immunization of Sows during Pregnancy against ETEC Infections.

Matías J, Berzosa M, Pastor Y, Irache JM, Gamazo C.

Vaccines (Basel). 2017 Dec 6;5(4). pii: E48. doi: 10.3390/vaccines5040048. Review.

16.

Oral immunotherapy using polymeric nanoparticles loaded with peanut proteins in a murine model of fatal anaphylaxis.

Gamazo C, García-Azpíroz M, Souza Rebouças J, Gastaminza G, Ferrer M, Irache JM.

Immunotherapy. 2017 Nov;9(15):1205-1217. doi: 10.2217/imt-2017-0111.

PMID:
29130802
17.

Corrigendum to 'Evaluation of the cytotoxicity, genotoxicity and mucus permeation capacity of several surface modified poly(anhydride) nanoparticles designed for oral drug delivery' [International Journal of Pharmaceutics 517 (2017) 67-79].

Iglesias T, de Cerain AL, Irache JM, Martín-Arbella N, Wilcox M, Pearson J, Azqueta A.

Int J Pharm. 2017 Nov 25;533(1):320. doi: 10.1016/j.ijpharm.2017.10.020. No abstract available.

PMID:
29056146
18.

Optimization and evaluation of zein nanoparticles to improve the oral delivery of glibenclamide. In vivo study using C. elegans.

Lucio D, Martínez-Ohárriz MC, Jaras G, Aranaz P, González-Navarro CJ, Radulescu A, Irache JM.

Eur J Pharm Biopharm. 2017 Dec;121:104-112. doi: 10.1016/j.ejpb.2017.09.018. Epub 2017 Oct 3.

PMID:
28986295
19.

Evaluation of nanoparticles as oral vehicles for immunotherapy against experimental peanut allergy.

Brotons-Canto A, Gamazo C, Martín-Arbella N, Abdulkarim M, Matías J, Gumbleton M, Irache JM.

Int J Biol Macromol. 2018 Apr 15;110:328-335. doi: 10.1016/j.ijbiomac.2017.09.109. Epub 2017 Sep 28.

PMID:
28965967
20.

Skin vaccination using microneedles coated with a plasmid DNA cocktail encoding nucleosomal histones of Leishmania spp.

Moreno E, Schwartz J, Calvo A, Blanco L, Larrea E, Irache JM, Sanmartín C, Coulman SA, Soto M, Birchall JC, Espuelas S.

Int J Pharm. 2017 Nov 25;533(1):236-244. doi: 10.1016/j.ijpharm.2017.09.055. Epub 2017 Sep 28.

PMID:
28964902
21.

A combination of nanosystems for the delivery of cancer chemoimmunotherapeutic combinations: 1-Methyltryptophan nanocrystals and paclitaxel nanoparticles.

Calleja P, Irache JM, Zandueta C, Martínez-Oharriz C, Espuelas S.

Pharmacol Res. 2017 Dec;126:77-83. doi: 10.1016/j.phrs.2017.09.004. Epub 2017 Sep 8.

PMID:
28893628
22.

Soybean protein-based microparticles for oral delivery of probiotics with improved stability during storage and gut resistance.

González-Ferrero C, Irache JM, González-Navarro CJ.

Food Chem. 2018 Jan 15;239:879-888. doi: 10.1016/j.foodchem.2017.07.022. Epub 2017 Jul 8.

PMID:
28873648
23.

Adjuvants for allergy immunotherapeutics.

Gamazo C, D'Amelio C, Gastaminza G, Ferrer M, Irache JM.

Hum Vaccin Immunother. 2017 Oct 3;13(10):2416-2427. doi: 10.1080/21645515.2017.1348447. Review.

24.

Supramolecular structure of glibenclamide and β-cyclodextrins complexes.

Lucio D, Irache JM, Font M, Martínez-Ohárriz MC.

Int J Pharm. 2017 Sep 15;530(1-2):377-386. doi: 10.1016/j.ijpharm.2017.08.002. Epub 2017 Aug 2.

PMID:
28779983
25.

Genotoxic evaluation of poly(anhydride) nanoparticles in the gastrointestinal tract of mice.

Iglesias T, Irache JM, Butinar M, Turk B, López de Cerain A, Azqueta A.

Int J Pharm. 2017 Sep 15;530(1-2):187-194. doi: 10.1016/j.ijpharm.2017.07.066. Epub 2017 Jul 24.

PMID:
28750895
26.

Effective protection of mice against Shigella flexneri with a new self-adjuvant multicomponent vaccine.

Pastor Y, Camacho A, Gil AG, Ramos R, Ceráin AL, Peñuelas I, Irache JM, Gamazo C.

J Med Microbiol. 2017 Jul;66(7):946-958. doi: 10.1099/jmm.0.000527. Epub 2017 Jul 19.

PMID:
28721849
27.

Toxicity and biodistribution of orally administered casein nanoparticles.

Gil AG, Irache JM, Peñuelas I, González Navarro CJ, López de Cerain A.

Food Chem Toxicol. 2017 Aug;106(Pt A):477-486. doi: 10.1016/j.fct.2017.06.020. Epub 2017 Jun 10.

PMID:
28610740
28.

Zein nanoparticles as vehicles for oral delivery purposes.

Irache JM, González-Navarro CJ.

Nanomedicine (Lond). 2017 Jun;12(11):1209-1211. doi: 10.2217/nnm-2017-0075. Epub 2017 May 18. No abstract available.

PMID:
28520512
29.

In vitro evaluation of the genotoxicity of poly(anhydride) nanoparticles designed for oral drug delivery.

Iglesias T, Dusinska M, El Yamani N, Irache JM, Azqueta A, López de Cerain A.

Int J Pharm. 2017 May 15;523(1):418-426. doi: 10.1016/j.ijpharm.2017.03.016. Epub 2017 Mar 9.

PMID:
28286081
30.

Improved effect of amikacin-loaded poly(D,L-lactide-co-glycolide) nanoparticles against planktonic and biofilm cells of Pseudomonas aeruginosa.

Sabaeifard P, Abdi-Ali A, Gamazo C, Irache JM, Soudi MR.

J Med Microbiol. 2017 Mar;66(2):137-148. doi: 10.1099/jmm.0.000430.

PMID:
28260589
31.

Nanoaggregation of inclusion complexes of glibenclamide with cyclodextrins.

Lucio D, Irache JM, Font M, Martínez-Ohárriz MC.

Int J Pharm. 2017 Mar 15;519(1-2):263-271. doi: 10.1016/j.ijpharm.2017.01.028. Epub 2017 Jan 19.

PMID:
28111282
32.

Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimer's disease.

Moreno LCGEI, Puerta E, Suárez-Santiago JE, Santos-Magalhães NS, Ramirez MJ, Irache JM.

Int J Pharm. 2017 Jan 30;517(1-2):50-57. doi: 10.1016/j.ijpharm.2016.11.061. Epub 2016 Nov 30.

PMID:
27915007
33.

Evaluation of the cytotoxicity, genotoxicity and mucus permeation capacity of several surface modified poly(anhydride) nanoparticles designed for oral drug delivery.

Iglesias T, López de Cerain A, Irache JM, Martín-Arbella N, Wilcox M, Pearson J, Azqueta A.

Int J Pharm. 2017 Jan 30;517(1-2):67-79. doi: 10.1016/j.ijpharm.2016.11.059. Epub 2016 Nov 28. Erratum in: Int J Pharm. 2017 Nov 25;533(1):320.

PMID:
27908629
34.

New pharmaceutical approaches for the treatment of food allergies.

Brotons-Canto A, Martín-Arbella N, Gamazo C, Irache JM.

Expert Opin Drug Deliv. 2018 Jul;15(7):675-686. doi: 10.1080/17425247.2016.1247805. Epub 2016 Oct 27. Review.

PMID:
27732129
35.

Zein nanoparticles for oral delivery of quercetin: Pharmacokinetic studies and preventive anti-inflammatory effects in a mouse model of endotoxemia.

Penalva R, González-Navarro CJ, Gamazo C, Esparza I, Irache JM.

Nanomedicine. 2017 Jan;13(1):103-110. doi: 10.1016/j.nano.2016.08.033. Epub 2016 Sep 8.

PMID:
27615118
36.

Amikacin loaded PLGA nanoparticles against Pseudomonas aeruginosa.

Sabaeifard P, Abdi-Ali A, Soudi MR, Gamazo C, Irache JM.

Eur J Pharm Sci. 2016 Oct 10;93:392-8. doi: 10.1016/j.ejps.2016.08.049. Epub 2016 Aug 26.

PMID:
27575877
37.

Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells.

Wang Z, Tan J, McConville C, Kannappan V, Tawari PE, Brown J, Ding J, Armesilla AL, Irache JM, Mei QB, Tan Y, Liu Y, Jiang W, Bian XW, Wang W.

Nanomedicine. 2017 Feb;13(2):641-657. doi: 10.1016/j.nano.2016.08.001. Epub 2016 Aug 10.

38.

Synthesis of Electroneutralized Amphiphilic Copolymers with Peptide Dendrons for Intramuscular Gene Delivery.

Pu L, Wang J, Li N, Chai Q, Irache JM, Wang G, Tang JZ, Gu Z.

ACS Appl Mater Interfaces. 2016 Jun 8;8(22):13724-34. doi: 10.1021/acsami.6b02592. Epub 2016 May 24.

PMID:
27181258
39.

Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles.

Huarte J, Espuelas S, Lai Y, He B, Tang J, Irache JM.

Int J Pharm. 2016 Jun 15;506(1-2):116-28. doi: 10.1016/j.ijpharm.2016.04.045. Epub 2016 Apr 19.

PMID:
27102993
40.

Toxicity evaluation of nanocarriers for the oral delivery of macromolecular drugs.

Ojer P, Iglesias T, Azqueta A, Irache JM, López de Cerain A.

Eur J Pharm Biopharm. 2015 Nov;97(Pt A):206-17. doi: 10.1016/j.ejpb.2015.10.005. Epub 2015 Oct 19. Review.

PMID:
26493712
41.

Interactions of poly (anhydride) nanoparticles with macrophages in light of their vaccine adjuvant properties.

Gamazo C, Bussmann H, Giemsa S, Camacho AI, Unsihuay D, Martín-Arbella N, Irache JM.

Int J Pharm. 2015 Dec 30;496(2):922-30. doi: 10.1016/j.ijpharm.2015.10.030. Epub 2015 Oct 20.

PMID:
26468037
42.

Assessment of β-lapachone loaded in lecithin-chitosan nanoparticles for the topical treatment of cutaneous leishmaniasis in L. major infected BALB/c mice.

Moreno E, Schwartz J, Larrea E, Conde I, Font M, Sanmartín C, Irache JM, Espuelas S.

Nanomedicine. 2015 Nov;11(8):2003-12. doi: 10.1016/j.nano.2015.07.011. Epub 2015 Aug 15.

PMID:
26282379
43.

Zein-Based Nanoparticles Improve the Oral Bioavailability of Resveratrol and Its Anti-inflammatory Effects in a Mouse Model of Endotoxic Shock.

Penalva R, Esparza I, Larraneta E, González-Navarro CJ, Gamazo C, Irache JM.

J Agric Food Chem. 2015 Jun 17;63(23):5603-11. doi: 10.1021/jf505694e. Epub 2015 Jun 9.

PMID:
26027429
44.

Mimicking microbial strategies for the design of mucus-permeating nanoparticles for oral immunization.

Gamazo C, Martín-Arbella N, Brotons A, Camacho AI, Irache JM.

Eur J Pharm Biopharm. 2015 Oct;96:454-63. doi: 10.1016/j.ejpb.2015.01.010. Epub 2015 Jan 20. Review.

PMID:
25615880
45.

Controlled Release, Intestinal Transport, and Oral Bioavailablity of Paclitaxel Can be Considerably Increased Using Suitably Tailored Pegylated Poly(Anhydride) Nanoparticles.

Calleja P, Espuelas S, Vauthier C, Ponchel G, Irache JM.

J Pharm Sci. 2015 Sep;104(9):2877-86. doi: 10.1002/jps.24354. Epub 2015 Jan 19.

PMID:
25600579
46.

Co-encapsulated CpG oligodeoxynucleotides and ovalbumin in PLGA microparticles; an in vitro and in vivo study.

San Román B, Gómez S, Irache JM, Espuelas S.

J Pharm Pharm Sci. 2014;17(4):541-53.

47.

In vivo study of the mucus-permeating properties of PEG-coated nanoparticles following oral administration.

Inchaurraga L, Martín-Arbella N, Zabaleta V, Quincoces G, Peñuelas I, Irache JM.

Eur J Pharm Biopharm. 2015 Nov;97(Pt A):280-9. doi: 10.1016/j.ejpb.2014.12.021. Epub 2014 Dec 23.

PMID:
25541441
48.

Nanoparticle based-immunotherapy against allergy.

Gamazo C, Gastaminza G, Ferrer M, Sanz ML, Irache JM.

Immunotherapy. 2014;6(7):885-97. doi: 10.2217/imt.14.63. Review.

PMID:
25290419
49.

Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo.

Liu P, Wang Z, Brown S, Kannappan V, Tawari PE, Jiang W, Irache JM, Tang JZ, Armesilla AL, Darling JL, Tang X, Wang W.

Oncotarget. 2014 Sep 15;5(17):7471-85.

50.

Development of a bacterial nanoparticle vaccine.

Gamazo C, Ochoa-Repáraz J, Tamayo I, Camacho A, Irache JM.

Methods Mol Biol. 2015;1225:139-49. doi: 10.1007/978-1-4939-1625-2_10.

PMID:
25253254

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