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Items: 18


A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides.

Richelle GJJ, Schmidt M, Ippel H, Hackeng TM, van Maarseveen JH, Nuijens T, Timmerman P.

Chembiochem. 2018 Sep 17;19(18):1934-1938. doi: 10.1002/cbic.201800346. Epub 2018 Aug 2.


Optical signature of nerve tissue-Exploratory ex vivo study comparing optical, histological, and molecular characteristics of different adipose and nerve tissues.

Balthasar AJR, Bydlon TM, Ippel H, van der Voort M, Hendriks BHW, Lucassen GW, van Geffen GJ, van Kleef M, van Dijk P, Lataster A.

Lasers Surg Med. 2018 Sep;50(9):948-960. doi: 10.1002/lsm.22938. Epub 2018 May 14.


Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaah6650. doi: 10.1126/scitranslmed.aah6650.


Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation.

Agten SM, Koenen RR, Ippel H, Eckardt V, von Hundelshausen P, Mayo KH, Weber C, Hackeng TM.

Angew Chem Int Ed Engl. 2016 Nov 21;55(48):14963-14966. doi: 10.1002/anie.201607036. Epub 2016 Oct 27.


Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR.

Ippel H, Miller MC, Vértesy S, Zheng Y, Cañada FJ, Suylen D, Umemoto K, Romanò C, Hackeng T, Tai G, Leffler H, Kopitz J, André S, Kübler D, Jiménez-Barbero J, Oscarson S, Gabius HJ, Mayo KH.

Glycobiology. 2016 Aug;26(8):888-903. doi: 10.1093/glycob/cww021. Epub 2016 Feb 23.


Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5.

Alard JE, Ortega-Gomez A, Wichapong K, Bongiovanni D, Horckmans M, Megens RT, Leoni G, Ferraro B, Rossaint J, Paulin N, Ng J, Ippel H, Suylen D, Hinkel R, Blanchet X, Gaillard F, D'Amico M, von Hundelshausen P, Zarbock A, Scheiermann C, Hackeng TM, Steffens S, Kupatt C, Nicolaes GA, Weber C, Soehnlein O.

Sci Transl Med. 2015 Dec 9;7(317):317ra196. doi: 10.1126/scitranslmed.aad5330.


Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain.

Miller MC, Ippel H, Suylen D, Klyosov AA, Traber PG, Hackeng T, Mayo KH.

Glycobiology. 2016 Jan;26(1):88-99. doi: 10.1093/glycob/cwv073.


A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles.

Hu Q, van Gaal EV, Brundel P, Ippel H, Hackeng T, Rijcken CJ, Storm G, Hennink WE, Prakash J.

J Control Release. 2015 May 10;205:98-108. doi: 10.1016/j.jconrel.2014.12.023. Epub 2015 Jan 10.


Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.

Karagöz GE, Duarte AM, Akoury E, Ippel H, Biernat J, Morán Luengo T, Radli M, Didenko T, Nordhues BA, Veprintsev DB, Dickey CA, Mandelkow E, Zweckstetter M, Boelens R, Madl T, Rüdiger SG.

Cell. 2014 Feb 27;156(5):963-74. doi: 10.1016/j.cell.2014.01.037.


(1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.

Ippel H, Miller MC, Berbís MA, Suylen D, André S, Hackeng TM, Cañada FJ, Weber C, Gabius HJ, Jiménez-Barbero J, Mayo KH.

Biomol NMR Assign. 2015 Apr;9(1):59-63. doi: 10.1007/s12104-014-9545-3. Epub 2014 Feb 7.


Peptides derived from human galectin-3 N-terminal tail interact with its carbohydrate recognition domain in a phosphorylation-dependent manner.

Berbís MÁ, André S, Cañada FJ, Pipkorn R, Ippel H, Mayo KH, Kübler D, Gabius HJ, Jiménez-Barbero J.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):126-31. doi: 10.1016/j.bbrc.2013.11.063. Epub 2013 Nov 22.


Chemoselective oxime reactions in proteins and peptides by using an optimized oxime strategy: the demise of levulinic acid.

Agten SM, Suylen D, Ippel H, Kokozidou M, Tans G, van de Vijver P, Koenen RR, Hackeng TM.

Chembiochem. 2013 Dec 16;14(18):2431-4. doi: 10.1002/cbic.201300598. Epub 2013 Oct 22. No abstract available.


Protein lysine-Nζ alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species.

Kumar N, Ippel H, Weber C, Hackeng T, Mayo KH.

Protein Sci. 2013 Mar;22(3):327-46. doi: 10.1002/pro.2214. Epub 2013 Jan 27.


N-terminal domain of human Hsp90 triggers binding to the cochaperone p23.

Karagöz GE, Duarte AM, Ippel H, Uetrecht C, Sinnige T, van Rosmalen M, Hausmann J, Heck AJ, Boelens R, Rüdiger SG.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):580-5. doi: 10.1073/pnas.1011867108. Epub 2010 Dec 23.


Multiple steps during the formation of beta-lactoglobulin fibrils.

Arnaudov LN, de Vries R, Ippel H, van Mierlo CP.

Biomacromolecules. 2003 Nov-Dec;4(6):1614-22.


The apical stem-loop of the hepatitis B virus encapsidation signal folds into a stable tri-loop with two underlying pyrimidine bulges.

Flodell S, Schleucher J, Cromsigt J, Ippel H, Kidd-Ljunggren K, Wijmenga S.

Nucleic Acids Res. 2002 Nov 1;30(21):4803-11.


Capture of a dimeric intermediate during transthyretin amyloid formation.

Olofsson A, Ippel HJ, Baranov V, Hörstedt P, Wijmenga S, Lundgren E.

J Biol Chem. 2001 Oct 26;276(43):39592-9. Epub 2001 Aug 22.


The solution structure of the homeodomain of the rat insulin-gene enhancer protein isl-1. Comparison with other homeodomains.

Ippel H, Larsson G, Behravan G, Zdunek J, Lundqvist M, Schleucher J, Lycksell PO, Wijmenga S.

J Mol Biol. 1999 May 14;288(4):689-703.


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