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Items: 46


SOX10 expression in mammary invasive ductal carcinomas and benign breast tissue.

Chiu K, Ionescu DN, Hayes M.

Virchows Arch. 2019 Mar 23. doi: 10.1007/s00428-019-02557-1. [Epub ahead of print]


Clinical outcomes after whole-genome sequencing in patients with metastatic non-small-cell lung cancer.

Tsang ES, Shen Y, Chooback N, Ho C, Jones M, Renouf DJ, Lim H, Sun S, Yip S, Pleasance E, Ionescu DN, Mungall K, Kasaian K, Ma Y, Zhao Y, Mungall A, Moore R, Jones SJM, Marra M, Laskin J.

Cold Spring Harb Mol Case Stud. 2019 Feb 1;5(1). pii: a002659. doi: 10.1101/mcs.a002659. Print 2019 Feb.


Canadian perspectives: update on inhibition of ALK-positive tumours in advanced non-small-cell lung cancer.

Melosky B, Cheema P, Agulnik J, Albadine R, Bebb DG, Blais N, Burkes R, Butts C, Card PB, Chan AMY, Hirsh V, Ionescu DN, Juergens R, Morzycki W, Poonja Z, Sangha R, Tehfe M, Tsao MS, Vincent M, Xu Z, Liu G.

Curr Oncol. 2018 Oct;25(5):317-328. doi: 10.3747/co.25.4379. Epub 2018 Oct 31. Review.


Harmonization of PD-L1 testing in oncology: a Canadian pathology perspective.

Ionescu DN, Downes MR, Christofides A, Tsao MS.

Curr Oncol. 2018 Jun;25(3):e209-e216. doi: 10.3747/co.25.4031. Epub 2018 Jun 28. Review.


Standardizing biomarker testing for Canadian patients with advanced lung cancer.

Melosky B, Blais N, Cheema P, Couture C, Juergens R, Kamel-Reid S, Tsao MS, Wheatley-Price P, Xu Z, Ionescu DN.

Curr Oncol. 2018 Feb;25(1):73-82. doi: 10.3747/co.25.3867. Epub 2018 Feb 28.


Practical Updates on Gastrointestinal Pathology From the CAMP 2017 Conference.

Ionescu DN.

Arch Pathol Lab Med. 2018 Jan;142(1):16. doi: 10.5858/arpa.2017-0393-ED. No abstract available.


Metastatic non-small cell lung carcinoma a mimic of primary breast carcinoma-case series and literature review.

Ali RH, Taraboanta C, Mohammad T, Hayes MM, Ionescu DN.

Virchows Arch. 2018 May;472(5):771-777. doi: 10.1007/s00428-017-2262-4. Epub 2017 Nov 5. Review.


The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency.

Cressman S, Peacock SJ, Tammemägi MC, Evans WK, Leighl NB, Goffin JR, Tremblay A, Liu G, Manos D, MacEachern P, Bhatia R, Puksa S, Nicholas G, McWilliams A, Mayo JR, Yee J, English JC, Pataky R, McPherson E, Atkar-Khattra S, Johnston MR, Schmidt H, Shepherd FA, Soghrati K, Amjadi K, Burrowes P, Couture C, Sekhon HS, Yasufuku K, Goss G, Ionescu DN, Hwang DM, Martel S, Sin DD, Tan WC, Urbanski S, Xu Z, Tsao MS, Lam S.

J Thorac Oncol. 2017 Aug;12(8):1210-1222. doi: 10.1016/j.jtho.2017.04.021. Epub 2017 May 10.


A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia.

Lam S, Mandrekar SJ, Gesthalter Y, Allen Ziegler KL, Seisler DK, Midthun DE, Mao JT, Aubry MC, McWilliams A, Sin DD, Shaipanich T, Liu G, Johnson E, Bild A, Lenburg ME, Ionescu DN, Mayo J, Yi JE, Tazelaar H, Harmsen WS, Smith J, Spira AE, Beane J, Limburg PJ, Szabo E; Cancer Prevention Network.

Cancer Prev Res (Phila). 2016 Dec;9(12):906-914. Epub 2016 Sep 22.


Investigation of PD-L1 Biomarker Testing Methods for PD-1 Axis Inhibition in Non-squamous Non-small Cell Lung Cancer.

Sheffield BS, Fulton R, Kalloger SE, Milne K, Geller G, Jones M, Jacquemont C, Zachara S, Zhao E, Pleasance E, Laskin J, Jones SJ, Marra MA, Yip S, Nelson BH, Gown AM, Ho C, Ionescu DN.

J Histochem Cytochem. 2016 Oct;64(10):587-600. doi: 10.1369/0022155416665338. Epub 2016 Sep 2.


Insights on the "Why, When, and How" of Integrating Molecular Testing in Anatomic Pathology Practice: Dedicated to the Memory of Gregory J. Naus, MD (1951-2015).

Ionescu DN.

Arch Pathol Lab Med. 2016 Aug;140(8):746-7. doi: 10.5858/arpa.2016-0192-ED. No abstract available.


Canadian consensus: inhibition of ALK-positive tumours in advanced non-small-cell lung cancer.

Melosky B, Agulnik J, Albadine R, Banerji S, Bebb DG, Bethune D, Blais N, Butts C, Cheema P, Cheung P, Cohen V, Deschenes J, Ionescu DN, Juergens R, Kamel-Reid S, Laurie SA, Liu G, Morzycki W, Tsao MS, Xu Z, Hirsh V.

Curr Oncol. 2016 Jun;23(3):196-200. doi: 10.3747/co.23.3120. Epub 2016 Jun 9.


Low Prevalence of High-Grade Lesions Detected With Autofluorescence Bronchoscopy in the Setting of Lung Cancer Screening in the Pan-Canadian Lung Cancer Screening Study.

Tremblay A, Taghizadeh N, McWilliams AM, MacEachern P, Stather DR, Soghrati K, Puksa S, Goffin JR, Yasufuku K, Amjadi K, Nicholas G, Martel S, Laberge F, Johnston M, Shepherd FA, Ionescu DN, Urbanski S, Hwang D, Cutz JC, Sekhon HS, Couture C, Xu Z, Sutedja TG, Atkar-Khattra S, Tammemagi MC, Tsao MS, Lam SC; Pan-Canadian Early Lung Cancer Study Group.

Chest. 2016 Nov;150(5):1015-1022. doi: 10.1016/j.chest.2016.04.019. Epub 2016 Apr 30.


Real-time endoscopic Raman spectroscopy for in vivo early lung cancer detection.

McGregor HC, Short MA, McWilliams A, Shaipanich T, Ionescu DN, Zhao J, Wang W, Chen G, Lam S, Zeng H.

J Biophotonics. 2017 Jan;10(1):98-110. doi: 10.1002/jbio.201500204. Epub 2016 Jan 8.


Endoscopic Doppler optical coherence tomography and autofluorescence imaging of peripheral pulmonary nodules and vasculature.

Pahlevaninezhad H, Lee AM, Ritchie A, Shaipanich T, Zhang W, Ionescu DN, Hohert G, MacAulay C, Lam S, Lane P.

Biomed Opt Express. 2015 Sep 30;6(10):4191-9. doi: 10.1364/BOE.6.004191. eCollection 2015 Oct 1.


Histologic classification of non-small-cell lung cancer over time: reducing the rates of not-otherwise-specified.

Ho C, Tong KM, Ramsden K, Ionescu DN, Laskin J.

Curr Oncol. 2015 Jun;22(3):e164-70. doi: 10.3747/co.22.2339.


Hsp27 Inhibition with OGX-427 Sensitizes Non-Small Cell Lung Cancer Cells to Erlotinib and Chemotherapy.

Lelj-Garolla B, Kumano M, Beraldi E, Nappi L, Rocchi P, Ionescu DN, Fazli L, Zoubeidi A, Gleave ME.

Mol Cancer Ther. 2015 May;14(5):1107-16. doi: 10.1158/1535-7163.MCT-14-0866. Epub 2015 Mar 4.


Primary pulmonary synovial sarcoma: a case report with unique and impressive computed tomography findings.

Kambo JS, Richardson B, Ionescu DN, Tucker T, Kraushaar G.

Can Respir J. 2015 Jan-Feb;22(1):e1-3.


Relationship of thyroid transcription factor 1 to EGFR status in non-small-cell lung cancer.

Sheffield BS, Bosdet IE, Ali RH, Young SS, McNeil BK, Wong C, Dastur K, Karsan A, Ionescu DN.

Curr Oncol. 2014 Dec;21(6):305-8. doi: 10.3747/co.21.2148.


Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada.

Cressman S, Lam S, Tammemagi MC, Evans WK, Leighl NB, Regier DA, Bolbocean C, Shepherd FA, Tsao MS, Manos D, Liu G, Atkar-Khattra S, Cromwell I, Johnston MR, Mayo JR, McWilliams A, Couture C, English JC, Goffin J, Hwang DM, Puksa S, Roberts H, Tremblay A, MacEachern P, Burrowes P, Bhatia R, Finley RJ, Goss GD, Nicholas G, Seely JM, Sekhon HS, Yee J, Amjadi K, Cutz JC, Ionescu DN, Yasufuku K, Martel S, Soghrati K, Sin DD, Tan WC, Urbanski S, Xu Z, Peacock SJ; Pan-Canadian Early Detection of Lung Cancer Study Team.

J Thorac Oncol. 2014 Oct;9(10):1449-58. doi: 10.1097/JTO.0000000000000283.


A prospective clinical utility and pharmacoeconomic study of the impact of the 21-gene Recurrence Score® assay in oestrogen receptor positive node negative breast cancer.

Davidson JA, Cromwell I, Ellard SL, Lohrisch C, Gelmon KA, Shenkier T, Villa D, Lim H, Sun S, Taylor S, Taylor M, Czerkawski B, Hayes M, Ionescu DN, Yoshizawa C, Chao C, Peacock S, Chia SK.

Eur J Cancer. 2013 Jul;49(11):2469-75. doi: 10.1016/j.ejca.2013.03.009. Epub 2013 Apr 20.


Thymoma: a population-based study of the management and outcomes for the province of British Columbia.

Mariano C, Ionescu DN, Cheung WY, Ali RH, Laskin J, Evans K, Carolan H, Murray N.

J Thorac Oncol. 2013 Jan;8(1):109-17. doi: 10.1097/JTO.0b013e318276241c.


Immunohistochemistry is a reliable screening tool for identification of ALK rearrangement in non-small-cell lung carcinoma and is antibody dependent.

Conklin CM, Craddock KJ, Have C, Laskin J, Couture C, Ionescu DN.

J Thorac Oncol. 2013 Jan;8(1):45-51. doi: 10.1097/JTO.0b013e318274a83e.


EGFR tyrosine kinase mutation testing in the treatment of non-small-cell lung cancer.

Kamel-Reid S, Chong G, Ionescu DN, Magliocco AM, Spatz A, Tsao M, Weng X, Young S, Zhang T, Soulieres D.

Curr Oncol. 2012 Apr;19(2):e67-74. doi: 10.3747/co.19.862.


Using laser Raman spectroscopy to reduce false positives of autofluorescence bronchoscopies: a pilot study.

Short MA, Lam S, McWilliams AM, Ionescu DN, Zeng H.

J Thorac Oncol. 2011 Jul;6(7):1206-14. doi: 10.1097/JTO.0b013e3182178ef7.


A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of non-small cell lung cancer.

Ellis PM, Blais N, Soulieres D, Ionescu DN, Kashyap M, Liu G, Melosky B, Reiman T, Romeo P, Shepherd FA, Tsao MS, Leighl NB.

J Thorac Oncol. 2011 Aug;6(8):1379-91. doi: 10.1097/JTO.0b013e318220cb8e. Review.


Optimal immunohistochemical markers for distinguishing lung adenocarcinomas from squamous cell carcinomas in small tumor samples.

Terry J, Leung S, Laskin J, Leslie KO, Gown AM, Ionescu DN.

Am J Surg Pathol. 2010 Dec;34(12):1805-11. doi: 10.1097/PAS.0b013e3181f7dae3.


BCL-2 expression is prognostic for improved survival in non-small cell lung cancer.

Renouf DJ, Wood-Baker R, Ionescu DN, Leung S, Masoudi H, Gilks CB, Laskin J.

J Thorac Oncol. 2009 Apr;4(4):486-91. doi: 10.1097/JTO.0b013e318199e03a.


Ovarian carcinoma subtypes are different diseases: implications for biomarker studies.

Köbel M, Kalloger SE, Boyd N, McKinney S, Mehl E, Palmer C, Leung S, Bowen NJ, Ionescu DN, Rajput A, Prentice LM, Miller D, Santos J, Swenerton K, Gilks CB, Huntsman D.

PLoS Med. 2008 Dec 2;5(12):e232. doi: 10.1371/journal.pmed.0050232.


Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma.

Gilks CB, Ionescu DN, Kalloger SE, Köbel M, Irving J, Clarke B, Santos J, Le N, Moravan V, Swenerton K; Cheryl Brown Ovarian Cancer Outcomes Unit of the British Columbia Cancer Agency.

Hum Pathol. 2008 Aug;39(8):1239-51. doi: 10.1016/j.humpath.2008.01.003. Epub 2008 Jul 7.


A pleural mass with pulmonary infiltrates.

Ryerson CJ, Malhotra S, Lam S, English JC, Ionescu DN.

Thorax. 2007 Aug;62(8):666, 695. No abstract available.


Parvovirus B19 infection in the immunocompromised host.

Florea AV, Ionescu DN, Melhem MF.

Arch Pathol Lab Med. 2007 May;131(5):799-804. Review.


Nonsmall cell lung carcinoma with neuroendocrine differentiation--an entity of no clinical or prognostic significance.

Ionescu DN, Treaba D, Gilks CB, Leung S, Renouf D, Laskin J, Wood-Baker R, Gown AM.

Am J Surg Pathol. 2007 Jan;31(1):26-32.


A 75-year-old man with an asymptomatic pleural-based mass discovered on routine chest radiographs. Primary pleural thymoma.

Qing G, Ionescu DN, Colby TV, Leslie KO.

Arch Pathol Lab Med. 2006 Apr;130(4):e62-5. No abstract available.


Metastatic basal cell carcinoma: four case reports, review of literature, and immunohistochemical evaluation.

Ionescu DN, Arida M, Jukic DM.

Arch Pathol Lab Med. 2006 Jan;130(1):45-51.


Attenuated familial adenomatous polyposis: a case report with mixed features and review of genotype-phenotype correlation.

Ionescu DN, Papachristou G, Schoen RE, Hedge M, Richards CS, Monzon FA.

Arch Pathol Lab Med. 2005 Nov;129(11):1401-4.


C4d deposition in lung allografts is associated with circulating anti-HLA alloantibody.

Ionescu DN, Girnita AL, Zeevi A, Duquesnoy R, Pilewski J, Johnson B, Studer S, McCurry KR, Yousem SA.

Transpl Immunol. 2005 Oct;15(1):63-8. Epub 2005 Jun 2.


Pulmonary crystal-storing histiocytoma.

Ionescu DN, Pierson DM, Qing G, Li M, Colby TV, Leslie KO.

Arch Pathol Lab Med. 2005 Sep;129(9):1159-63.


Recurrent sarcoidosis in lung transplant allografts: granulomas are of recipient origin.

Ionescu DN, Hunt JL, Lomago D, Yousem SA.

Diagn Mol Pathol. 2005 Sep;14(3):140-5.


Patterns of allelic loss of synchronous adenocarcinomas of the lung.

Dacic S, Ionescu DN, Finkelstein S, Yousem SA.

Am J Surg Pathol. 2005 Jul;29(7):897-902.


Persistent fever in a lung transplant patient.

Ionescu DN, Dacic S.

Arch Pathol Lab Med. 2005 Jun;129(6):e153-4. No abstract available.


Pathologic quiz case: a 33-year-old woman with a large temporal mass. Chondroblastoma of the skull.

Ionescu DN, McFadden K, Unni KK, Couce ME.

Arch Pathol Lab Med. 2005 Apr;129(4):539-40. No abstract available.


Protein expression and gene amplification of epidermal growth factor receptor in thymomas.

Ionescu DN, Sasatomi E, Cieply K, Nola M, Dacic S.

Cancer. 2005 Feb 1;103(3):630-6.


Epidermoid metaplasia of the cervix.

Ionescu DN, Mohan D, Carter G, Dabbs DJ.

Arch Pathol Lab Med. 2004 Sep;128(9):1052-3. No abstract available.


Pulmonary meningothelial-like nodules: a genotypic comparison with meningiomas.

Ionescu DN, Sasatomi E, Aldeeb D, Omalu BI, Finkelstein SD, Swalsky PA, Yousem SA.

Am J Surg Pathol. 2004 Feb;28(2):207-14.


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