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Items: 1 to 50 of 405

1.

Induction of Apoptosis and Cytotoxicity by Raphasatin in Human Breast Adenocarcinoma MCF-7 Cells.

Ibrahim MD, Kntayya SB, Mohd Ain N, Iori R, Ioannides C, Abdull Razis AF.

Molecules. 2018 Nov 27;23(12). pii: E3092. doi: 10.3390/molecules23123092.

2.

MRI-guided frameless biopsy robotic system with the inclusion of unfocused ultrasound transducer for brain cancer ablation.

Giannakou M, Yiallouras C, Menikou G, Ioannides C, Damianou C.

Int J Med Robot. 2019 Feb;15(1):e1951. doi: 10.1002/rcs.1951. Epub 2018 Sep 12.

PMID:
30157310
3.

Induction of Apoptosis and Cytotoxicity by Isothiocyanate Sulforaphene in Human Hepatocarcinoma HepG2 Cells.

Kntayya SB, Ibrahim MD, Mohd Ain N, Iori R, Ioannides C, Abdull Razis AF.

Nutrients. 2018 Jun 4;10(6). pii: E718. doi: 10.3390/nu10060718.

4.

Osteoid osteoma of the scaphoid bone associated with flexor carpi radialis calcific tendinitis and treated with CT-guided RF ablation.

Michaelides M, Drakonaki E, Petridou E, Pantziara M, Ioannides C.

Skeletal Radiol. 2018 Oct;47(10):1449-1453. doi: 10.1007/s00256-018-2926-4. Epub 2018 Mar 14.

PMID:
29541786
5.

Antagonistic and synergistic interactions during the binding of binary mixtures of polycyclic aromatic hydrocarbons to the aryl hydrocarbon receptor.

Pushparajah DS, Ioannides C.

Toxicol In Vitro. 2018 Aug;50:54-61. doi: 10.1016/j.tiv.2018.02.011. Epub 2018 Feb 19.

PMID:
29471110
6.

Isothiocyanates and Xenobiotic Detoxification.

Abdull Razis AF, Konsue N, Ioannides C.

Mol Nutr Food Res. 2018 Sep;62(18):e1700916. doi: 10.1002/mnfr.201700916. Epub 2018 Feb 12. Review.

PMID:
29288567
7.

MRI-compatible breast/rib phantom for evaluating ultrasonic thermal exposures.

Menikou G, Yiannakou M, Yiallouras C, Ioannides C, Damianou C.

Int J Med Robot. 2018 Feb;14(1). doi: 10.1002/rcs.1849. Epub 2017 Jul 17.

PMID:
28714565
8.

MRI guided focused ultrasound robotic system for animal experiments.

Yiannakou M, Menikou G, Yiallouras C, Ioannides C, Damianou C.

Int J Med Robot. 2017 Dec;13(4). doi: 10.1002/rcs.1804. Epub 2017 Feb 17.

PMID:
28211622
9.

Up-regulation of CYP1A1 and phase II enzymes by 5-ring isomeric polycyclic aromatic hydrocarbons in precision-cut rat hepatic slices: Importance of molecular shape.

Pushparajah D, Lewis D, Ioannides C.

Toxicol In Vitro. 2017 Apr;40:203-213. doi: 10.1016/j.tiv.2017.01.011. Epub 2017 Jan 16.

PMID:
28104439
10.

Spinal osteoid osteoma progressed to osteoblastoma with paraspinal soft tissue mass: a unique presentation.

Michaelides M, Pantziara M, Petridou E, Iacovou E, Ioannides C.

Skeletal Radiol. 2017 Mar;46(3):379-383. doi: 10.1007/s00256-016-2555-8. Epub 2016 Dec 20.

PMID:
27999873
11.

MRI-compatible bone phantom for evaluating ultrasonic thermal exposures.

Menikou G, Yiannakou M, Yiallouras C, Ioannides C, Damianou C.

Ultrasonics. 2016 Sep;71:12-19. doi: 10.1016/j.ultras.2016.05.020. Epub 2016 May 25.

PMID:
27261569
12.

Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices.

Pushparajah DS, Plant KE, Plant NJ, Ioannides C.

Environ Toxicol. 2017 Mar;32(3):764-775. doi: 10.1002/tox.22276. Epub 2016 Apr 20.

13.

A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism.

Ioannides C, Konsue N.

Drug Metab Rev. 2015 Aug;47(3):356-73. doi: 10.3109/03602532.2015.1058819. Epub 2015 Jun 29. Review.

PMID:
26119477
14.
15.

A perivesical mass in a 79-year-old with a treated adenocarcinoma of the prostate.

Georgiades F, Ioannides C, Kourieos A, Grange P, Kouriefs C.

Urology. 2015 Apr;85(4):713-6. doi: 10.1016/j.urology.2014.11.007. Epub 2015 Jan 21. No abstract available.

PMID:
25618558
16.

Potential drug interactions with melatonin.

Papagiannidou E, Skene DJ, Ioannides C.

Physiol Behav. 2014 May 28;131:17-24. doi: 10.1016/j.physbeh.2014.04.016. Epub 2014 Apr 13.

PMID:
24732412
17.

The search for in vitro systems. (preface).

Lake BG, Vickers AE, Ioannides C.

Xenobiotica. 2013 Jan;43(1):1. doi: 10.3109/00498254.2013.735827. Epub 2012 Oct 25. No abstract available.

PMID:
23094663
18.

Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices.

Ioannides C.

Xenobiotica. 2013 Jan;43(1):15-28. doi: 10.3109/00498254.2012.698766. Epub 2012 Jun 28. Review.

PMID:
22742738
19.

A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.

Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.

Eur J Nutr. 2013 Apr;52(3):1279-85. doi: 10.1007/s00394-012-0397-2. Epub 2012 Jun 19.

PMID:
22710810
20.

The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.

Abdull Razis AF, Hanlon N, Soltys E, Krizova V, Iori R, Plant KE, Plant N, Ioannides C.

Arch Toxicol. 2012 Oct;86(10):1505-14. doi: 10.1007/s00204-012-0875-6. Epub 2012 May 30.

PMID:
22643862
21.

Characterization of the temporal induction of hepatic xenobiotic-metabolizing enzymes by glucosinolates and isothiocyanates: requirement for at least a 6 h exposure to elicit complete induction profile.

Razis AF, Bagatta M, De Nicola GR, Iori R, Plant N, Ioannides C.

J Agric Food Chem. 2012 Jun 6;60(22):5556-64. doi: 10.1021/jf3011195. Epub 2012 May 24.

PMID:
22594452
22.

Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor.

Abdull Razis AF, Konsue N, Dervetzoglou M, Plant KE, Plant N, Ioannides C.

Mol Nutr Food Res. 2012 Mar;56(3):425-34. doi: 10.1002/mnfr.201100548. Epub 2011 Dec 16.

PMID:
22174033
23.

Debrisoquine metabolism and CYP2D expression in marmoset liver microsomes.

Cooke BR, Bligh SW, Cybulski ZR, Ioannides C, Hall M.

Drug Metab Dispos. 2012 Jan;40(1):70-5. doi: 10.1124/dmd.111.041566. Epub 2011 Oct 5.

PMID:
21976620
24.

4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.

Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.

Arch Toxicol. 2012 Feb;86(2):183-94. doi: 10.1007/s00204-011-0750-x. Epub 2011 Sep 30.

PMID:
21960141
25.

Folate receptor α: a storied past and promising future in immunotherapy.

Clifton GT, Sears AK, Clive KS, Holmes JP, Mittendorf EA, Ioannides CG, Ponniah S, Peoples GE.

Hum Vaccin. 2011 Feb;7(2):183-90. Epub 2011 Feb 1. Review.

PMID:
21321484
26.

Exposure to isothiocyanates suppresses urinary mutagenicity in rats treated with heterocyclic amine IQ: lack of association with CYP1 activity.

Hanlon N, Konsue N, Coldham N, Sauer MJ, Ioannides C.

Nutr Cancer. 2011;63(2):300-5. doi: 10.1080/01635581.2011.530735.

PMID:
21298592
27.

A peptidoglycan monomer with the glutamine to serine change and basic peptides bind in silico to TLR-2 (403-455).

Li Y, Efferson CL, Ramesh R, Peoples GE, Hwu P, Ioannides CG.

Cancer Immunol Immunother. 2011 Apr;60(4):515-24. doi: 10.1007/s00262-010-0959-1. Epub 2010 Dec 28.

PMID:
21188584
28.

Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.

Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.

Arch Toxicol. 2011 Aug;85(8):919-27. doi: 10.1007/s00204-010-0629-2. Epub 2010 Dec 5.

PMID:
21132492
30.

Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables.

Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.

Toxicology. 2010 Nov 9;277(1-3):74-85. doi: 10.1016/j.tox.2010.08.080. Epub 2010 Sep 15.

PMID:
20833222
31.

The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer.

Abdull Razis AF, Iori R, Ioannides C.

Int J Cancer. 2011 Jun 15;128(12):2775-82. doi: 10.1002/ijc.25620. Epub 2010 Nov 9.

32.

Adenovirus-mediated interleukin (IL)-24 immunotherapy for cancer.

Ramesh R, Ioannides CG, Roth JA, Chada S.

Methods Mol Biol. 2010;651:241-70. doi: 10.1007/978-1-60761-786-0_14.

PMID:
20686970
33.

Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin.

Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.

Lung Cancer. 2011 Mar;71(3):298-305. doi: 10.1016/j.lungcan.2010.06.015. Epub 2010 Jul 17.

PMID:
20638746
34.

Differential response of four human livers to modulation of phase II enzyme systems by the chemopreventive phytochemical phenethyl isothiocyanate.

Konsue N, Ioannides C.

Mol Nutr Food Res. 2010 Oct;54(10):1477-85. doi: 10.1002/mnfr.200900598.

PMID:
20440691
35.

Created Gli-1 duplex short-RNA (i-Gli-RNA) eliminates CD44 Hi progenitors of taxol-resistant ovarian cancer cells.

Mine T, Matsueda S, Gao H, Li Y, Wong KK, Peoples GE, Ferrone S, Ioannides CG.

Oncol Rep. 2010 Jun;23(6):1537-43.

36.

Phenethyl isocyanate is not the metabolite of phenethyl isothiocyanate responsible for mechanism-based inhibition of cytochrome P450.

Konsue N, Ioannides C.

Arch Toxicol. 2010 Oct;84(10):751-9. doi: 10.1007/s00204-010-0522-z. Epub 2010 Feb 7.

PMID:
20140730
37.
38.

Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats.

Konsue N, Kirkpatrick J, Kuhnert N, King LJ, Ioannides C.

Mol Nutr Food Res. 2010 Mar;54(3):426-32. doi: 10.1002/mnfr.200900090.

PMID:
19866468
39.

N-terminally LRMK-linked HER-2 peptides, AE-37 [p776(774-788)] and AE-47 [Ava-F7(776-788)], aid differentiation of E75-TCR+CD8+ cells to perforin-positive cells.

Matsueda S, Gao H, Efferson CL, Tsuda N, Ishiyama S, Li Y, Ioannides MG, Fisk B, Peoples GE, Ioannides CG.

Anticancer Res. 2009 Jul;29(7):2427-35.

40.

The aliphatic isothiocyanates erucin and sulforaphane do not effectively up-regulate NAD(P)H:quinone oxidoreductase (NQO1) in human liver compared with rat.

Hanlon N, Poynton CL, Coldham N, Sauer MJ, Ioannides C.

Mol Nutr Food Res. 2009 Jul;53(7):836-44. doi: 10.1002/mnfr.200800292.

PMID:
19536870
41.

Repeated intake of broccoli does not lead to higher plasma levels of sulforaphane in human volunteers.

Hanlon N, Coldham N, Gielbert A, Sauer MJ, Ioannides C.

Cancer Lett. 2009 Oct 18;284(1):15-20. doi: 10.1016/j.canlet.2009.04.004. Epub 2009 May 5.

PMID:
19409695
43.

Synthetic microRNA targeting glioma-associated antigen-1 protein.

Tsuda N, Mine T, Ioannides CG, Chang DZ.

Methods Mol Biol. 2009;487:435-49. doi: 10.1007/978-1-60327-547-7_21.

PMID:
19301660
44.

Longterm followup assessment of a HER2/neu peptide (E75) vaccine for prevention of recurrence in high-risk prostate cancer patients.

Gates JD, Carmichael MG, Benavides LC, Holmes JP, Hueman MT, Woll MM, Ioannides CG, Robson CH, McLeod DG, Ponniah S, Peoples GE.

J Am Coll Surg. 2009 Feb;208(2):193-201. doi: 10.1016/j.jamcollsurg.2008.10.018.

PMID:
19228530
45.

Effect of 2-amino-9H-pyrido[2,3-b]indole (AalphaC), a carcinogenic heterocyclic amine present in food, on atherosclerotic plaque development in apoE deficient mice.

Lopez-Mendez C, Bermudez-Fajardo A, Ioannides C, Oviedo-Orta E.

Toxicol Lett. 2009 Mar 10;185(2):73-8. doi: 10.1016/j.toxlet.2008.11.014. Epub 2008 Dec 3.

PMID:
19103270
46.

Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells.

Mine T, Matsueda S, Li Y, Tokumitsu H, Gao H, Danes C, Wong KK, Wang X, Ferrone S, Ioannides CG.

Cancer Immunol Immunother. 2009 Aug;58(8):1185-94. doi: 10.1007/s00262-008-0623-1. Epub 2008 Dec 2.

47.

Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate.

Konsue N, Ioannides C.

Food Chem Toxicol. 2008 Dec;46(12):3677-83. doi: 10.1016/j.fct.2008.09.046. Epub 2008 Sep 26.

PMID:
18929617
48.

Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane.

Hanlon N, Coldham N, Sauer MJ, Ioannides C.

Chem Biol Interact. 2009 Jan 27;177(2):115-20. doi: 10.1016/j.cbi.2008.08.015. Epub 2008 Sep 7.

PMID:
18823965
49.

Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane.

Hanlon N, Coldham N, Sauer MJ, Ioannides C.

Toxicology. 2008 Oct 30;252(1-3):92-8. doi: 10.1016/j.tox.2008.08.002. Epub 2008 Aug 19.

PMID:
18773935
50.

Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices.

Staal YC, Pushparajah DS, van Herwijnen MH, Gottschalk RW, Maas LM, Ioannides C, van Schooten FJ, van Delft JH.

Mutagenesis. 2008 Nov;23(6):491-9. doi: 10.1093/mutage/gen041. Epub 2008 Aug 18.

PMID:
18711122

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