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Items: 8

1.

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice.

Young J, Dominicus C, Wagener J, Butterworth S, Ye X, Kelly G, Ordan M, Saunders B, Instrell R, Howell M, Stewart A, Treeck M.

Nat Commun. 2019 Sep 3;10(1):3963. doi: 10.1038/s41467-019-11855-w.

2.

APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.

Sansregret L, Patterson JO, Dewhurst S, López-García C, Koch A, McGranahan N, Chao WCH, Barry DJ, Rowan A, Instrell R, Horswell S, Way M, Howell M, Singleton MR, Medema RH, Nurse P, Petronczki M, Swanton C.

Cancer Discov. 2017 Feb;7(2):218-233. doi: 10.1158/2159-8290.CD-16-0645. Epub 2017 Jan 9.

3.

Multiomic Analysis of the UV-Induced DNA Damage Response.

Boeing S, Williamson L, Encheva V, Gori I, Saunders RE, Instrell R, Aygün O, Rodriguez-Martinez M, Weems JC, Kelly GP, Conaway JW, Conaway RC, Stewart A, Howell M, Snijders AP, Svejstrup JQ.

Cell Rep. 2016 May 17;15(7):1597-1610. doi: 10.1016/j.celrep.2016.04.047. Epub 2016 May 12.

4.

The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.

Dombernowsky SL, Samsøe-Petersen J, Petersen CH, Instrell R, Hedegaard AM, Thomas L, Atkins KM, Auclair S, Albrechtsen R, Mygind KJ, Fröhlich C, Howell M, Parker P, Thomas G, Kveiborg M.

Nat Commun. 2015 Jun 25;6:7518. doi: 10.1038/ncomms8518.

5.

HTS-DB: an online resource to publish and query data from functional genomics high-throughput siRNA screening projects.

Saunders RE, Instrell R, Rispoli R, Jiang M, Howell M.

Database (Oxford). 2013 Oct 11;2013:bat072. doi: 10.1093/database/bat072. Print 2013.

6.

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.

Wehr MC, Holder MV, Gailite I, Saunders RE, Maile TM, Ciirdaeva E, Instrell R, Jiang M, Howell M, Rossner MJ, Tapon N.

Nat Cell Biol. 2013 Jan;15(1):61-71.

7.

Tales from an academic RNAi screening facility; FAQs.

Jiang M, Instrell R, Saunders B, Berven H, Howell M.

Brief Funct Genomics. 2011 Jul;10(4):227-37. doi: 10.1093/bfgp/elr016. Epub 2011 Apr 28.

PMID:
21527443
8.

PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.

Kveiborg M, Instrell R, Rowlands C, Howell M, Parker PJ.

PLoS One. 2011 Feb 28;6(2):e17168. doi: 10.1371/journal.pone.0017168.

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