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Items: 1 to 50 of 865

1.

Investigation of Receptor-Mediated Cyanocobalamin (Vitamin B12) Transport across the Inner Blood-Retinal Barrier Using Fluorescence-Labeled Cyanocobalamin.

Kinoshita Y, Nogami K, Jomura R, Akanuma SI, Abe H, Inouye M, Kubo Y, Hosoya KI.

Mol Pharm. 2018 Jul 17. doi: 10.1021/acs.molpharmaceut.8b00617. [Epub ahead of print]

PMID:
29966424
2.

Spontaneous Helix Formation of " meta"-Ethynylphenol Oligomers by Sequential Intramolecular Hydrogen Bonding inside the Cavities.

Hayashi T, Ohishi Y, Hee-Soo S, Abe H, Matsumoto S, Inouye M.

J Org Chem. 2018 Jun 8. doi: 10.1021/acs.joc.8b00996. [Epub ahead of print]

PMID:
29856213
3.

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam.

Holt KE, McAdam P, Thai PVK, Thuong NTT, Ha DTM, Lan NN, Lan NH, Nhu NTQ, Hai HT, Ha VTN, Thwaites G, Edwards DJ, Nath AP, Pham K, Ascher DB, Farrar J, Khor CC, Teo YY, Inouye M, Caws M, Dunstan SJ.

Nat Genet. 2018 Jun;50(6):849-856. doi: 10.1038/s41588-018-0117-9. Epub 2018 May 21.

PMID:
29785015
4.

Nonplanar Macrocycle Consisting of Four Pyridine and Phenol Units Connected with Acetylene Bonds Displaying Preferential Binding to Maltoside over Monosaccharides.

Ohishi Y, Yamamoto N, Abe H, Inouye M.

J Org Chem. 2018 May 18;83(10):5766-5770. doi: 10.1021/acs.joc.8b00062. Epub 2018 May 8.

PMID:
29709177
5.

Hexaphenolic Rigid Cages Prepared by Self-Organization of C3 v Tridentates.

Abe H, Hashikawa D, Minami T, Ohtani K, Masuda K, Matsumoto S, Inouye M.

J Org Chem. 2018 Mar 16;83(6):3132-3141. doi: 10.1021/acs.joc.7b03111. Epub 2018 Mar 7.

PMID:
29473751
6.

Validation and implementation of Planova™ BioEX virus filters in the manufacture of a new liquid intravenous immunoglobulin in China.

Ma S, Pang GL, Shao YJ, Hongo-Hirasaki T, Shang MX, Inouye M, Jian CY, Zhu MZ, Yang HH, Gao JF, Xi ZY, Song DW.

Biologicals. 2018 Mar;52:37-43. doi: 10.1016/j.biologicals.2018.01.004. Epub 2018 Feb 9.

PMID:
29434001
7.

Widespread transcriptional pausing and elongation control at enhancers.

Henriques T, Scruggs BS, Inouye MO, Muse GW, Williams LH, Burkholder AB, Lavender CA, Fargo DC, Adelman K.

Genes Dev. 2018 Jan 1;32(1):26-41. doi: 10.1101/gad.309351.117. Epub 2018 Jan 29.

8.

Bcl-XL-binding helical peptides possessing d-Ala residues at their C-termini with the advantage of long-lasting intracellular stabilities.

Nogami K, Tokumaru H, Isokawa G, Oyoshi T, Fujimoto K, Inouye M.

Chem Commun (Camb). 2017 Nov 7;53(89):12104-12107. doi: 10.1039/c7cc06904a.

PMID:
29072724
9.

Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular Mimicry.

Gray LA, D'Antoine HA, Tong SYC, McKinnon M, Bessarab D, Brown N, Reményi B, Steer A, Syn G, Blackwell JM, Inouye M, Carapetis JR.

J Infect Dis. 2017 Dec 12;216(11):1460-1470. doi: 10.1093/infdis/jix497.

PMID:
29029143
10.

Corrigendum: In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.

Ingle DJ, Valcanis M, Kuzevski A, Tauschek M, Inouye M, Stinear T, Levine MM, Robins-Browne RM, Holt KE.

Microb Genom. 2017 Aug 1;3(7):e000109. doi: 10.1099/mgen.0.000109. eCollection 2017 Jul.

11.

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.

Nath AP, Ritchie SC, Byars SG, Fearnley LG, Havulinna AS, Joensuu A, Kangas AJ, Soininen P, Wennerström A, Milani L, Metspalu A, Männistö S, Würtz P, Kettunen J, Raitoharju E, Kähönen M, Juonala M, Palotie A, Ala-Korpela M, Ripatti S, Lehtimäki T, Abraham G, Raitakari O, Salomaa V, Perola M, Inouye M.

Genome Biol. 2017 Aug 1;18(1):146. doi: 10.1186/s13059-017-1279-y.

12.

An exposome perspective: Early-life events and immune development in a changing world.

Renz H, Holt PG, Inouye M, Logan AC, Prescott SL, Sly PD.

J Allergy Clin Immunol. 2017 Jul;140(1):24-40. doi: 10.1016/j.jaci.2017.05.015. Review.

PMID:
28673401
13.

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.

Byars SG, Huang QQ, Gray LA, Bakshi A, Ripatti S, Abraham G, Stearns SC, Inouye M.

PLoS Genet. 2017 Jun 22;13(6):e1006328. doi: 10.1371/journal.pgen.1006328. eCollection 2017 Jun.

14.

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure.

Marques FZ, Prestes PR, Byars SG, Ritchie SC, Würtz P, Patel SK, Booth SA, Rana I, Minoda Y, Berzins SP, Curl CL, Bell JR, Wai B, Srivastava PM, Kangas AJ, Soininen P, Ruohonen S, Kähönen M, Lehtimäki T, Raitoharju E, Havulinna A, Perola M, Raitakari O, Salomaa V, Ala-Korpela M, Kettunen J, McGlynn M, Kelly J, Wlodek ME, Lewandowski PA, Delbridge LM, Burrell LM, Inouye M, Harrap SB, Charchar FJ.

J Am Heart Assoc. 2017 Jun 14;6(6). pii: e005971. doi: 10.1161/JAHA.117.005971.

15.

Translation-dependent mRNA cleavage by YhaV in Escherichia coli.

Choi W, Yamaguchi Y, Lee JW, Jang KM, Inouye M, Kim SG, Yoon MH, Park JH.

FEBS Lett. 2017 Jul;591(13):1853-1861. doi: 10.1002/1873-3468.12705. Epub 2017 Jun 26.

16.

FlashPCA2: principal component analysis of Biobank-scale genotype datasets.

Abraham G, Qiu Y, Inouye M.

Bioinformatics. 2017 Sep 1;33(17):2776-2778. doi: 10.1093/bioinformatics/btx299.

PMID:
28475694
17.

Characterization of YjjJ toxin of Escherichia coli.

Maeda Y, Lin CY, Ishida Y, Inouye M, Yamaguchi Y, Phadtare S.

FEMS Microbiol Lett. 2017 Jun 15;364(11). doi: 10.1093/femsle/fnx086.

PMID:
28430938
18.

Toxins of Prokaryotic Toxin-Antitoxin Systems with Sequence-Specific Endoribonuclease Activity.

Masuda H, Inouye M.

Toxins (Basel). 2017 Apr 14;9(4). pii: E140. doi: 10.3390/toxins9040140. Review.

19.

In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.

Ingle DJ, Valcanis M, Kuzevski A, Tauschek M, Inouye M, Stinear T, Levine MM, Robins-Browne RM, Holt KE.

Microb Genom. 2016 Jul 11;2(7):e000064. doi: 10.1099/mgen.0.000064. eCollection 2016 Jul. Erratum in: Microb Genom. 2017 Aug 01;3(7):e000109.

20.

Deletion of mazF increases Staphylococcus aureus biofilm formation in an ica-dependent manner.

Kato F, Yabuno Y, Yamaguchi Y, Sugai M, Inouye M.

Pathog Dis. 2017 Jul 31;75(5). doi: 10.1093/femspd/ftx026.

PMID:
28334216
21.

Interactions within the MHC contribute to the genetic architecture of celiac disease.

Goudey B, Abraham G, Kikianty E, Wang Q, Rawlinson D, Shi F, Haviv I, Stern L, Kowalczyk A, Inouye M.

PLoS One. 2017 Mar 10;12(3):e0172826. doi: 10.1371/journal.pone.0172826. eCollection 2017.

22.

Designing of a single gene encoding four functional proteins.

Inouye M, Ishida Y, Inouye K.

J Theor Biol. 2017 Apr 21;419:266-268. doi: 10.1016/j.jtbi.2017.01.042. Epub 2017 Feb 3.

PMID:
28167103
23.

The role of the loop 1 region in MazFbs mRNA interferase from Bacillus subtilis in recognition of the 3' end of the RNA substrate.

Ishida Y, Inouye K, Inouye M.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):403-408. doi: 10.1016/j.bbrc.2016.12.130. Epub 2016 Dec 23.

PMID:
28017721
24.

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.

Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X.

BMC Genomics. 2016 Nov 4;17(1):874.

25.

The first demonstration of the existence of reverse transcriptases in bacteria.

Inouye M.

Gene. 2017 Jan 15;597:76-77. doi: 10.1016/j.gene.2016.10.031. Epub 2016 Oct 21. Review.

PMID:
27777111
26.

The first discovery of RNA interference by RNA restriction enzymes to inhibit protein synthesis.

Inouye M.

Gene. 2017 Jan 15;597:78-79. doi: 10.1016/j.gene.2016.10.025. Epub 2016 Oct 21. Review.

PMID:
27777107
27.

D3h -Symmetrical Shape-Persistent Macrocycles Consisting of Pyridine-Acetylene-Phenol Conjugates as an Efficient Host Architecture for Saccharide Recognition.

Abe H, Yoneda T, Ohishi Y, Inouye M.

Chemistry. 2016 Dec 23;22(52):18944-18952. doi: 10.1002/chem.201603987. Epub 2016 Nov 22.

PMID:
27739118
28.

Vitamin D over the first decade and susceptibility to childhood allergy and asthma.

Hollams EM, Teo SM, Kusel M, Holt BJ, Holt KE, Inouye M, De Klerk NH, Zhang G, Sly PD, Hart PH, Holt PG.

J Allergy Clin Immunol. 2017 Feb;139(2):472-481.e9. doi: 10.1016/j.jaci.2016.07.032. Epub 2016 Oct 7.

PMID:
27726947
29.

Preferential use of minor codons in the translation initiation region of human genes.

Park JH, Kwon M, Yamaguchi Y, Firestein BL, Park JY, Yun J, Yang JO, Inouye M.

Hum Genet. 2017 Jan;136(1):67-74. doi: 10.1007/s00439-016-1735-x. Epub 2016 Oct 11.

PMID:
27726012
30.

Genomic prediction of coronary heart disease.

Abraham G, Havulinna AS, Bhalala OG, Byars SG, De Livera AM, Yetukuri L, Tikkanen E, Perola M, Schunkert H, Sijbrands EJ, Palotie A, Samani NJ, Salomaa V, Ripatti S, Inouye M.

Eur Heart J. 2016 Nov 14;37(43):3267-3278. Epub 2016 Sep 21.

31.

The first application of site-directed mutagenesis using oligonucleotides for studying the function of a protein.

Inouye M.

Gene. 2016 Nov 30;593(2):342-3. doi: 10.1016/j.gene.2016.08.038. Epub 2016 Aug 28. Review. No abstract available.

PMID:
27581785
32.

A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets.

Ritchie SC, Watts S, Fearnley LG, Holt KE, Abraham G, Inouye M.

Cell Syst. 2016 Jul;3(1):71-82. doi: 10.1016/j.cels.2016.06.012.

33.

Microbial Factors Associated with Postoperative Crohn's Disease Recurrence.

Wright EK, Kamm MA, Wagner J, Teo SM, Cruz P, Hamilton AL, Ritchie KJ, Inouye M, Kirkwood CD.

J Crohns Colitis. 2017 Feb;11(2):191-203. doi: 10.1093/ecco-jcc/jjw136. Epub 2016 Jul 27.

PMID:
27466174
34.

The first demonstration of RNA interference to inhibit mRNA function.

Inouye M.

Gene. 2016 Nov 5;592(2):332-3. doi: 10.1016/j.gene.2016.07.024. Epub 2016 Jul 9. Review.

PMID:
27404040
35.

The first attempt for the isolation of an intact mRNA for structure determination.

Inouye M.

Gene. 2016 Nov 5;592(2):331. doi: 10.1016/j.gene.2016.07.005. Epub 2016 Jul 5. Review.

PMID:
27390087
36.

Highly efficient residue-selective labeling with isotope-labeled Ile, Leu, and Val using a new auxotrophic E. coli strain.

Miyanoiri Y, Ishida Y, Takeda M, Terauchi T, Inouye M, Kainosho M.

J Biomol NMR. 2016 Jun;65(2):109-19. doi: 10.1007/s10858-016-0042-0. Epub 2016 Jun 6.

PMID:
27272978
37.

Exploiting E. coli auxotrophs for leucine, valine, and threonine specific methyl labeling of large proteins for NMR applications.

Monneau YR, Ishida Y, Rossi P, Saio T, Tzeng SR, Inouye M, Kalodimos CG.

J Biomol NMR. 2016 Jun;65(2):99-108. doi: 10.1007/s10858-016-0041-1. Epub 2016 Jun 2.

38.

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection.

Ritchie SC, Würtz P, Nath AP, Abraham G, Havulinna AS, Fearnley LG, Sarin AP, Kangas AJ, Soininen P, Aalto K, Seppälä I, Raitoharju E, Salmi M, Maksimow M, Männistö S, Kähönen M, Juonala M, Ripatti S, Lehtimäki T, Jalkanen S, Perola M, Raitakari O, Salomaa V, Ala-Korpela M, Kettunen J, Inouye M.

Cell Syst. 2015 Oct 28;1(4):293-301. doi: 10.1016/j.cels.2015.09.007. Epub 2015 Oct 22.

39.

Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks.

Fearnley LG, Inouye M.

Int J Epidemiol. 2016 Oct;45(5):1319-1328. Epub 2016 Apr 26. Review.

40.

Modeling Rett Syndrome Using Human Induced Pluripotent Stem Cells.

Andoh-Noda T, Inouye MO, Miyake K, Kubota T, Okano H, Akamatsu W.

CNS Neurol Disord Drug Targets. 2016;15(5):544-50. Review.

PMID:
27071793
41.

Cyclodextrin-Isolated Alkynylpyrenes as UV-Stable and Blue-Light-Emitting Molecules Even in Condensed States.

Inouye M, Yoshizawa A, Shibata M, Yonenaga Y, Fujimoto K, Sakata T, Matsumoto S, Shiro M.

Org Lett. 2016 May 6;18(9):1960-3. doi: 10.1021/acs.orglett.6b00420. Epub 2016 Apr 8.

PMID:
27058597
42.

Suppression of the toxicity of Bac7 (1-35), a bovine peptide antibiotic, and its production in E. coli.

Ishida Y, Inouye M.

AMB Express. 2016 Mar;6(1):19. doi: 10.1186/s13568-016-0190-3. Epub 2016 Mar 2.

43.

ydfD encodes a novel lytic protein in Escherichia coli.

Masuda H, Awano N, Inouye M.

FEMS Microbiol Lett. 2016 Mar;363(6). pii: fnw039. doi: 10.1093/femsle/fnw039. Epub 2016 Feb 16.

44.

The first determination of DNA sequence of a specific gene.

Inouye M.

Gene. 2016 May 10;582(1):94-5. doi: 10.1016/j.gene.2016.01.038. Epub 2016 Feb 6.

PMID:
26855436
45.

Discrete Molecular Recognition Induced Higher-Order Structures: Fibrous Formation Triggered by Melamine Recognition with a Cationic Ethynylpyridine Macrocyclic Host.

Suzuki D, Abe H, Inouye M.

Org Lett. 2016 Jan 15;18(2):320-3. doi: 10.1021/acs.orglett.5b03502. Epub 2016 Jan 7.

PMID:
26741650
46.

An endogenous protein inhibitor, YjhX (TopAI), for topoisomerase I from Escherichia coli.

Yamaguchi Y, Inouye M.

Nucleic Acids Res. 2015 Dec 2;43(21):10387-96. doi: 10.1093/nar/gkv1197. Epub 2015 Nov 8.

47.

Native Mannose-Dominant Extraction by Pyridine-Phenol Alternating Oligomers Having an Extremely Efficient Repeating Motif of Hydrogen-Bonding Acceptors and Donors.

Ohishi Y, Abe H, Inouye M.

Chemistry. 2015 Nov 9;21(46):16504-11. doi: 10.1002/chem.201503149. Epub 2015 Sep 25.

PMID:
26406480
48.

Synthesis of Nonnatural Oligonucleotides Made Exclusively of Alkynyl C-Nucleosides with Nonnatural Bases.

Chiba J, Inouye M.

Curr Protoc Nucleic Acid Chem. 2015 Jun 3;61:4.62.1-22. doi: 10.1002/0471142700.nc0462s61.

PMID:
26344228
49.

Structural analysis of the mechanism of phosphorylation of a critical autoregulatory tyrosine residue in FGFR1 kinase domain.

Kobashigawa Y, Amano S, Yokogawa M, Kumeta H, Morioka H, Inouye M, Schlessinger J, Inagaki F.

Genes Cells. 2015 Oct;20(10):860-70. doi: 10.1111/gtc.12277. Epub 2015 Aug 24.

50.

Genomic prediction of celiac disease targeting HLA-positive individuals.

Abraham G, Rohmer A, Tye-Din JA, Inouye M.

Genome Med. 2015 Jul 16;7(1):72. doi: 10.1186/s13073-015-0196-5. eCollection 2015.

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