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Items: 9

1.

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans.

Tirosh A, Calay ES, Tuncman G, Claiborn KC, Inouye KE, Eguchi K, Alcala M, Rathaus M, Hollander KS, Ron I, Livne R, Heianza Y, Qi L, Shai I, Garg R, Hotamisligil GS.

Sci Transl Med. 2019 Apr 24;11(489). pii: eaav0120. doi: 10.1126/scitranslmed.aav0120.

PMID:
31019023
2.

TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis.

Liu L, Inouye KE, Allman WR, Coleman AS, Siddiqui S, Hotamisligil GS, Akkoyunlu M.

Diabetes. 2018 Aug;67(8):1589-1603. doi: 10.2337/db17-1089. Epub 2018 Jun 5.

3.

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakg├╝l G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS.

Nat Med. 2018 Mar;24(3):292-303. doi: 10.1038/nm.4481. Epub 2018 Feb 5.

4.

Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.

Burak MF, Inouye KE, White A, Lee A, Tuncman G, Calay ES, Sekiya M, Tirosh A, Eguchi K, Birrane G, Lightwood D, Howells L, Odede G, Hailu H, West S, Garlish R, Neale H, Doyle C, Moore A, Hotamisligil GS.

Sci Transl Med. 2015 Dec 23;7(319):319ra205. doi: 10.1126/scitranslmed.aac6336. Epub 2015 Dec 23.

PMID:
26702093
5.

The role of adipocyte XBP1 in metabolic regulation during lactation.

Gregor MF, Misch ES, Yang L, Hummasti S, Inouye KE, Lee AH, Bierie B, Hotamisligil GS.

Cell Rep. 2013 May 30;3(5):1430-9. doi: 10.1016/j.celrep.2013.03.042. Epub 2013 Apr 25.

6.

The effect of long-term insulin treatment with and without antecedent hypoglycemia on neuropeptide and corticosteroid receptor expression in the brains of diabetic rats.

Inouye KE, Chan O, Yue JT, Andrews M, Li Q, Matthews SG, Vranic M.

Brain Res Bull. 2008 Oct 22;77(4):149-57. doi: 10.1016/j.brainresbull.2008.07.001. Epub 2008 Jul 29.

PMID:
18672033
7.

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

Inouye KE, Shi H, Howard JK, Daly CH, Lord GM, Rollins BJ, Flier JS.

Diabetes. 2007 Sep;56(9):2242-50. Epub 2007 May 1.

8.

Effects of insulin treatment without and with recurrent hypoglycemia on hypoglycemic counterregulation and adrenal catecholamine-synthesizing enzymes in diabetic rats.

Inouye KE, Yue JT, Chan O, Kim T, Akirav EM, Park E, Riddell MC, Burdett E, Matthews SG, Vranic M.

Endocrinology. 2006 Apr;147(4):1860-70. Epub 2006 Jan 5.

PMID:
16396986
9.

Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal system and hypothalamo-pituitary-adrenal axis.

Inouye KE, Chan O, Yue JT, Matthews SG, Vranic M.

Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E422-9. Epub 2004 Oct 19.

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