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The association between health-related quality of life and achievement of personalized symptom goal.

Tagami K, Kawaguchi T, Miura T, Yamaguchi T, Matsumoto Y, Watanabe YS, Uehara Y, Okizaki A, Inoue A, Morita T, Kinoshita H.

Support Care Cancer. 2020 Jan 22. doi: 10.1007/s00520-020-05316-0. [Epub ahead of print]


Epithelioid glioblastoma presenting as multicentric glioma: A case report and review of the literature.

Kohno D, Inoue A, Fukushima M, Aki T, Matsumoto S, Suehiro S, Nishikawa M, Ozaki S, Shigekawa S, Watanabe H, Kitazawa R, Kunieda T.

Surg Neurol Int. 2020 Jan 17;11:8. doi: 10.25259/SNI_544_2019. eCollection 2020.


Structural insight into small molecule action on Frizzleds.

Kozielewicz P, Turku A, Bowin CF, Petersen J, Valnohova J, Cañizal MCA, Ono Y, Inoue A, Hoffmann C, Schulte G.

Nat Commun. 2020 Jan 21;11(1):414. doi: 10.1038/s41467-019-14149-3.


Angiopoietin-1/Tie-2 signal after focal traumatic brain injury is potentiated by BQ788, an ETB receptor antagonist, in the mouse cerebrum: Involvement in recovery of blood-brain barrier function.

Michinaga S, Tanabe A, Nakaya R, Fukutome C, Inoue A, Iwane A, Minato Y, Tujiuchi Y, Miyake D, Mizuguchi H, Koyama Y.

J Neurochem. 2020 Jan 19. doi: 10.1111/jnc.14957. [Epub ahead of print]


Structure of the neurotensin receptor 1 in complex with β-arrestin 1.

Huang W, Masureel M, Qianhui Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK.

Nature. 2020 Jan 16. doi: 10.1038/s41586-020-1953-1. [Epub ahead of print]


Prognostic significance of immunohistochemical subtypes based on the stage of B-cell differentiation in primary CNS lymphoma.

Inoue A, Ohnishi T, Kohno S, Matsumoto S, Nishikawa M, Ohue S, Ozaki S, Suehiro S, Kurata M, Fukushima M, Kitazawa R, Shigekawa S, Watanabe H, Kunieda T.

Int J Clin Exp Pathol. 2019 Apr 1;12(4):1457-1467. eCollection 2019.


Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500.

Nagiri C, Shihoya W, Inoue A, Kadji FMN, Aoki J, Nureki O.

Commun Biol. 2019 Jun 21;2(1):236. doi: 10.1038/s42003-019-0482-7.


Activation of the GLP-1 receptor by a non-peptidic agonist.

Zhao P, Liang YL, Belousoff MJ, Deganutti G, Fletcher MM, Willard FS, Bell MG, Christe ME, Sloop KW, Inoue A, Truong TT, Clydesdale L, Furness SGB, Christopoulos A, Wang MW, Miller LJ, Reynolds CA, Danev R, Sexton PM, Wootten D.

Nature. 2020 Jan;577(7790):432-436. doi: 10.1038/s41586-019-1902-z. Epub 2020 Jan 8.


The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.

Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J, Iwata S.

Structure. 2019 Dec 21. pii: S0969-2126(19)30442-3. doi: 10.1016/j.str.2019.12.003. [Epub ahead of print]


Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics, and identify small molecule inhibitors.

Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE.

Br J Pharmacol. 2019 Dec 27. doi: 10.1111/bph.14960. [Epub ahead of print]


PLF-1 (Proliferin-1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia.

Hu L, Huang Z, Ishii H, Wu H, Suzuki S, Inoue A, Kim W, Jiang H, Li X, Zhu E, Piao L, Zhao G, Lei Y, Okumura K, Shi GP, Murohara T, Kuzuya M, Cheng XW.

J Am Heart Assoc. 2019 Dec 17;8(24):e005886. doi: 10.1161/JAHA.117.005886. Epub 2019 Dec 16.


Loss of Ikbkap/Elp1 in mouse oocytes causes spindle disorganization, developmental defects in preimplantation embryos and impaired female fertility.

Yang KT, Inoue A, Lee YJ, Jiang CL, Lin FJ.

Sci Rep. 2019 Dec 11;9(1):18875. doi: 10.1038/s41598-019-55090-1.


RBM10 regulates centriole duplication in HepG2 cells by ectopically assembling PLK4-STIL complexes in the nucleus.

Kunimoto H, Inoue A, Kojima H, Yang J, Zhao H, Tsuruta D, Nakajima K.

Genes Cells. 2019 Dec 9. doi: 10.1111/gtc.12741. [Epub ahead of print]


3D Vessel Image Reconstruction by MDCT for Surgical Indication and Timing of Strangulating Small Bowel Obstructions.

Murata M, Hiraki M, Hagiwara A, Sawami H, Suzuki R, Fukunaga H, Tanaka N, Inoue A, Takahashi H, Morita S.

World J Surg. 2019 Dec 6. doi: 10.1007/s00268-019-05310-6. [Epub ahead of print]


Application of Colloidal Dispersions of Bioshell Calcium Oxide (BiSCaO) for Disinfection.

Sato Y, Ohata H, Inoue A, Ishihara M, Nakamura S, Fukuda K, Takayama T, Murakami K, Hiruma S, Yokoe H.

Polymers (Basel). 2019 Dec 2;11(12). pii: E1991. doi: 10.3390/polym11121991.


Phase II study of S-1 in patients with previously-treated invasive thymoma and thymic carcinoma: North Japan lung cancer study group trial 1203.

Tsukita Y, Inoue A, Sugawara S, Kuyama S, Nakagawa T, Harada D, Tanaka H, Watanabe K, Mori Y, Harada T, Hino T, Fujii M, Ichinose M.

Lung Cancer. 2020 Jan;139:89-93. doi: 10.1016/j.lungcan.2019.10.016. Epub 2019 Oct 18.


Factors Associated With Regorafenib Adherence With Metastatic Colorectal Cancer.

Kawakami K, Wakatsuki T, Soejima A, Kobayashi K, Yokokawa T, Aoyama T, Suzuki K, Suenaga M, Yamaguchi K, Inoue A, Machida Y, Hama T.

Patient Prefer Adherence. 2019 Oct 15;13:1745-1750. doi: 10.2147/PPA.S217835. eCollection 2019.


Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study.

Hosomi Y, Morita S, Sugawara S, Kato T, Fukuhara T, Gemma A, Takahashi K, Fujita Y, Harada T, Minato K, Takamura K, Hagiwara K, Kobayashi K, Nukiwa T, Inoue A; North-East Japan Study Group.

J Clin Oncol. 2020 Jan 10;38(2):115-123. doi: 10.1200/JCO.19.01488. Epub 2019 Nov 4.


Acyl-CoA synthetase 6 regulates long-chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice.

Shishikura K, Kuroha S, Matsueda S, Iseki H, Matsui T, Inoue A, Arita M.

FASEB J. 2019 Dec;33(12):14194-14203. doi: 10.1096/fj.201901074R. Epub 2019 Oct 25.


Cathepsin S-Mediated Negative Regulation of Wnt5a/SC35 Activation Contributes to Ischemia-Induced Neovascularization in Aged Mice.

Xu W, Yu C, Piao L, Inoue A, Wang H, Meng X, Li X, Cui L, Umegaki H, Shi GP, Murohara T, Kuzuya M, Cheng XW.

Circ J. 2019 Nov 25;83(12):2537-2546. doi: 10.1253/circj.CJ-19-0325. Epub 2019 Oct 24.


Organizational justice and illness reporting among Japanese employees with chronic diseases.

Eguchi H, Tsutsumi A, Inoue A, Kachi Y.

PLoS One. 2019 Oct 21;14(10):e0223595. doi: 10.1371/journal.pone.0223595. eCollection 2019.


High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node.

Simmons S, Sasaki N, Umemoto E, Uchida Y, Fukuhara S, Kitazawa Y, Okudaira M, Inoue A, Tohya K, Aoi K, Aoki J, Mochizuki N, Matsuno K, Takeda K, Miyasaka M, Ishii M.

Elife. 2019 Oct 1;8. pii: e41239. doi: 10.7554/eLife.41239.


Computed tomography diagnosis of transomental hernia.

Inoue A, Furukawa A.

Jpn J Radiol. 2019 Dec;37(12):860-861. doi: 10.1007/s11604-019-00879-3. Epub 2019 Sep 21. No abstract available.


E-cadherin-Fc chimera protein matrix enhances cancer stem-like properties and induces mesenchymal features in colon cancer cells.

Qian Y, Wu X, Yokoyama Y, Okuzaki D, Taguchi M, Hirose H, Wang J, Hata T, Inoue A, Hiraki M, Ohtsuka M, Takahashi H, Haraguchi N, Mizushima T, Tanaka S, Mori M, Yamamoto H.

Cancer Sci. 2019 Nov;110(11):3520-3532. doi: 10.1111/cas.14193. Epub 2019 Sep 30.


Spatial regulation of GPR64/ADGRG2 signaling by β-arrestins and GPCR kinases.

Azimzadeh P, Talamantez-Lyburn SC, Chang KT, Inoue A, Balenga N.

Ann N Y Acad Sci. 2019 Nov;1456(1):26-43. doi: 10.1111/nyas.14227. Epub 2019 Sep 9.


Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research.

Inoue A, Deem AK, Kopetz S, Heffernan TP, Draetta GF, Carugo A.

Cancers (Basel). 2019 Sep 6;11(9). pii: E1321. doi: 10.3390/cancers11091321. Review.


In Response to the Letter to the Editor: Auditory and Vestibular Dysfunction in M. 3243A>G Carriers.

Inoue A, Iwasaki S.

Otol Neurotol. 2019 Oct;40(9):1260-1261. doi: 10.1097/MAO.0000000000002412. No abstract available.


Association between psychosocial factors at work and health outcomes after retirement: a protocol for a systematic review and meta-analysis.

Imamura K, Tsutsumi A, Asai Y, Arima H, Ando E, Inoue A, Inoue R, Iwanaga M, Eguchi H, Otsuka Y, Kobayashi Y, Sakuraya A, Sasaki N, Tsuno K, Hino A, Watanabe K, Shimazu A, Kawakami N.

BMJ Open. 2019 Aug 27;9(8):e030773. doi: 10.1136/bmjopen-2019-030773.


Long-term maintenance of functional primary human hepatocytes using small molecules.

Katsuda T, Kawamata M, Inoue A, Yamaguchi T, Abe M, Ochiya T.

FEBS Lett. 2020 Jan;594(1):114-125. doi: 10.1002/1873-3468.13582. Epub 2019 Aug 30.


Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.

Buenaventura T, Bitsi S, Laughlin WE, Burgoyne T, Lyu Z, Oqua AI, Norman H, McGlone ER, Klymchenko AS, Corrêa IR Jr, Walker A, Inoue A, Hanyaloglu A, Grimes J, Koszegi Z, Calebiro D, Rutter GA, Bloom SR, Jones B, Tomas A.

PLoS Biol. 2019 Aug 20;17(8):e3000097. doi: 10.1371/journal.pbio.3000097. eCollection 2019 Aug.


Existential and Mindfulness-Based Intervention to Increase Self-Compassion in Apparently Healthy Subjects (the EXMIND Study): A Randomized Controlled Trial.

Sakai A, Terao T, Kawano N, Akase M, Hatano K, Shirahama M, Hirakawa H, Kohno K, Inoue A, Ishii N.

Front Psychiatry. 2019 Aug 2;10:538. doi: 10.3389/fpsyt.2019.00538. eCollection 2019.


Accuracy, criteria, and clinical significance of visual assessment on diffusion-weighted imaging and apparent diffusion coefficient quantification for diagnosing acute appendicitis.

Inoue A, Furukawa A, Nitta N, Takaki K, Ota S, Zen Y, Kojima M, Akabori H, Ohta H, Mekata E, Saotome T, Murata K.

Abdom Radiol (NY). 2019 Oct;44(10):3235-3245. doi: 10.1007/s00261-019-02180-3.


Association between rewarming duration and neurological outcome in out-of-hospital cardiac arrest patients receiving therapeutic hypothermia.

Hifumi T, Inoue A, Kokubu N, Hase M, Yonemoto N, Kuroda Y, Kawakita K, Sawano H, Tahara Y, Nishioka K, Shirai S, Hazui H, Arimoto H, Kashiwase K, Kasaoka S, Motomura T, Yasuga Y, Yokoyama H, Nagao K, Nonogi H; J-PULSE-Hypo Investigators.

Resuscitation. 2020 Jan 1;146:170-177. doi: 10.1016/j.resuscitation.2019.07.029. Epub 2019 Aug 5.


Measuring eudemonic well-being at work: a validation study for the 24-item The University of Tokyo Occupational Mental Health well-being scale among Japanese workers.

Watanabe K, Imamura K, Inoue A, Otsuka Y, Shimazu A, Eguchi H, Adachi H, Sakuraya A, Kobayashi Y, Arima H, Kawakami N.

Ind Health. 2019 Aug 1. doi: 10.2486/indhealth.2019-0074. [Epub ahead of print]


[A Case of Right Frontal Dermoid Cyst with Temporal Imaging Changes in the Desease Course].

Nakamura Y, Iwata S, Inoue A, Ohue S, Fukumoto S, Ichikawa H, Onoue S, Ozaki S, Kohno K.

No Shinkei Geka. 2019 Jul;47(7):769-776. doi: 10.11477/mf.1436204021. Japanese.


Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm.

Raimondi F, Inoue A, Kadji FMN, Shuai N, Gonzalez JC, Singh G, de la Vega AA, Sotillo R, Fischer B, Aoki J, Gutkind JS, Russell RB.

Oncogene. 2019 Sep;38(38):6491-6506. doi: 10.1038/s41388-019-0895-2. Epub 2019 Jul 23.


Psychosocial work environment explains the association of job dissatisfaction with long-term sickness absence: a one-year prospect study of Japanese employees.

Inoue A, Tsutsumi A, Kachi Y, Eguchi H, Shimazu A, Kawakami N.

J Epidemiol. 2019 Jul 13. doi: 10.2188/jea.JE20190050. [Epub ahead of print]


Magnetic Resonance Imaging Findings of Intrapulmonary Hematoma.

Wada H, Sakashita T, Inoue A.

Am J Med Sci. 2019 Oct;358(4):e17. doi: 10.1016/j.amjms.2019.05.007. Epub 2019 May 25. No abstract available.


Cathepsin S Deficiency Mitigated Chronic Stress-Related Neointimal Hyperplasia in Mice.

Wang H, Meng X, Piao L, Inoue A, Xu W, Yu C, Nakamura K, Hu L, Sasaki T, Wu H, Unno K, Umegaki H, Murohara T, Shi GP, Kuzuya M, Cheng XW.

J Am Heart Assoc. 2019 Jul 16;8(14):e011994. doi: 10.1161/JAHA.119.011994. Epub 2019 Jul 12.


Refractory Chest Pain Induced by Implantable Cardioverter-Defibrillator in a Patient with Advanced Cancer: What Is the Best Timing for Deactivation of an ICD?

Hiratsuka Y, Tagami K, Inoue A.

J Palliat Med. 2019 Jul;22(7):745-746. doi: 10.1089/jpm.2019.0126. No abstract available.


Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500.

Nagiri C, Shihoya W, Inoue A, Kadji FMN, Aoki J, Nureki O.

Commun Biol. 2019 Jun 21;2:236. doi: 10.1038/s42003-019-0482-7. eCollection 2019.


Effects of Serum Albumin Levels on Antithrombin Supplementation Outcomes Among Patients With Sepsis-Associated Coagulopathy: A Retrospective Study.

Ebina M, Fujino K, Inoue A, Ariyoshi K, Eguchi Y.

Clin Med Insights Blood Disord. 2019 Jun 21;12:1179545X19858361. doi: 10.1177/1179545X19858361. eCollection 2019.


Clarifying Deeper Psychological Characteristics of Hikikomori Using the Rorschach Comprehensive System: A Pilot Case-Control Study.

Katsuki R, Inoue A, Indias S, Kurahara K, Kuwano N, Funatsu F, Kubo H, Kanba S, Kato TA.

Front Psychiatry. 2019 Jun 13;10:412. doi: 10.3389/fpsyt.2019.00412. eCollection 2019.


Conformational transitions of a neurotensin receptor 1-Gi1 complex.

Kato HE, Zhang Y, Hu H, Suomivuori CM, Kadji FMN, Aoki J, Krishna Kumar K, Fonseca R, Hilger D, Huang W, Latorraca NR, Inoue A, Dror RO, Kobilka BK, Skiniotis G.

Nature. 2019 Aug;572(7767):80-85. doi: 10.1038/s41586-019-1337-6. Epub 2019 Jun 26.


WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins.

Bowin CF, Inoue A, Schulte G.

J Biol Chem. 2019 Aug 2;294(31):11677-11684. doi: 10.1074/jbc.AC119.009412. Epub 2019 Jun 24.


Explicit prognostic disclosure to Asian women with breast cancer: A randomized, scripted video-vignette study (J-SUPPORT1601).

Mori M, Fujimori M, van Vliet LM, Yamaguchi T, Shimizu C, Kinoshita T, Morishita-Kawahara M, Inoue A, Inoguchi H, Matsuoka Y, Bruera E, Morita T, Uchitomi Y.

Cancer. 2019 Oct 1;125(19):3320-3329. doi: 10.1002/cncr.32327. Epub 2019 Jun 17.


Unveiling the partners of the DRBD2-mRNP complex, an RBP in Trypanosoma cruzi and ortholog to the yeast SR-protein Gbp2.

Wippel HH, Malgarin JS, Inoue AH, Leprevost FDV, Carvalho PC, Goldenberg S, Alves LR.

BMC Microbiol. 2019 Jun 11;19(1):128. doi: 10.1186/s12866-019-1505-8.


Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy.

Wu V, Yeerna H, Nohata N, Chiou J, Harismendy O, Raimondi F, Inoue A, Russell RB, Tamayo P, Gutkind JS.

J Biol Chem. 2019 Jul 19;294(29):11062-11086. doi: 10.1074/jbc.REV119.005601. Epub 2019 Jun 5. Review.


Social Support During Emergency Work and Subsequent Serious Psychological Distress: A Cross-Sectional Study Among Emergency Workers who Responded to the Fukushima Daiichi Nuclear Power Plant Accident.

Mafune K, Hiro H, Inoue A, Hino A, Shigemura J, Yamada M, Okubo T.

J Occup Environ Med. 2019 Jun;61(6):e240-e246. doi: 10.1097/JOM.0000000000001569.


CCR4 Blockade Depletes Regulatory T Cells and Prolongs Survival in a Canine Model of Bladder Cancer.

Maeda S, Murakami K, Inoue A, Yonezawa T, Matsuki N.

Cancer Immunol Res. 2019 Jul;7(7):1175-1187. doi: 10.1158/2326-6066.CIR-18-0751. Epub 2019 Jun 3.


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