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Effects of Protein-Energy Wasting (PEW) and hyperphosphatemia on the prognosis in Japanese maintenance hemodialysis patients: A five-year follow-up observational study.

Inoue A, Ishikawa E, Shirai Y, Murata T, Miki C, Hamada Y.

Clin Nutr ESPEN. 2020 Apr;36:134-138. doi: 10.1016/j.clnesp.2020.01.004. Epub 2020 Feb 4.


Strong adhesion of wet conducting polymers on diverse substrates.

Inoue A, Yuk H, Lu B, Zhao X.

Sci Adv. 2020 Mar 20;6(12):eaay5394. doi: 10.1126/sciadv.aay5394. eCollection 2020 Mar.


Letter to Editor about "A Case of Appendiceal Mucocele due to Low-grade Appendiceal Mucinous Neoplasm Correctly Differentiated from Acute Appendicitis Based on Diffusion-weighted Imaging and the Apparent Diffusion Coefficient Value (JJMRM 2020; 40: 14-19)".

Inoue A, Yoshida E, Otsuki A, Ohta H, Mekata E, Tsujikawa T, Watanabe S, Ota S, Nitta N, Murata K.

Magn Reson Med Sci. 2020 Mar 24. doi: 10.2463/mrms.lte.2020-0003. [Epub ahead of print] No abstract available.


Deficiency of cysteinyl cathepsin K suppresses the development of experimental intimal hyperplasia in response to chronic stress.

Meng X, Piao L, Wang H, Inoue A, Huang Z, Jiang H, Nakamura K, Sasaki T, Li X, Xu W, Yu C, Hu L, Wu H, Murohara T, Shi GP, Kuzuya M, Cheng XW.

J Hypertens. 2020 Mar 19. doi: 10.1097/HJH.0000000000002424. [Epub ahead of print]


Increased dipeptidyl peptidase-4 accelerates chronic stress-related thrombosis in a mouse carotid artery model.

Jin X, Jin C, Nakamura K, Jin T, Xin M, Wan Y, Yue X, Jin S, Wang H, Inoue A, Nan Y, Lin Z, Kuzuya M, Cheng XW.

J Hypertens. 2020 Mar 19. doi: 10.1097/HJH.0000000000002418. [Epub ahead of print]


Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest in Adult Patients.

Inoue A, Hifumi T, Sakamoto T, Kuroda Y.

J Am Heart Assoc. 2020 Apr 7;9(7):e015291. doi: 10.1161/JAHA.119.015291. Epub 2020 Mar 24.


Gamma Knife Surgery for Residual or Recurrent Craniopharyngioma After Surgical Resection: A Multi-institutional Retrospective Study in Japan.

Tsugawa T, Kobayashi T, Hasegawa T, Iwai Y, Matsunaga S, Yamamoto M, Hayashi M, Kenai H, Kano T, Mori H, Nagano O, Hasegawa S, Inoue A, Nagatomo Y, Onoue S, Sato M, Yasuda S.

Cureus. 2020 Feb 12;12(2):e6973. doi: 10.7759/cureus.6973.


Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR.

White AD, Jean-Alphonse FG, Fang F, Peña KA, Liu S, König GM, Inoue A, Aslanoglou D, Gellman SH, Kostenis E, Xiao K, Vilardaga JP.

Proc Natl Acad Sci U S A. 2020 Mar 17. pii: 201918158. doi: 10.1073/pnas.1918158117. [Epub ahead of print]


Construct validity and test-retest reliability of the World Mental Health Japan version of the World Health Organization Health and Performance Questionnaire Short Version: a preliminary study.

Kawakami N, Inoue A, Tsuchiya M, Watanabe K, Imamura K, Iida M, Nishi D.

Ind Health. 2020 Mar 14. doi: 10.2486/indhealth.2019-0090. [Epub ahead of print]


Production of a novel dimeric 4-deoxy-L-erythro-5-hexoseulose uronic acid by a PL-17 exolytic alginate lyase from Hydrogenophaga sp. UMI-18.

Narsico J, Inoue A, Oka S, Ojima T.

Biochem Biophys Res Commun. 2020 Mar 12. pii: S0006-291X(20)30508-8. doi: 10.1016/j.bbrc.2020.03.029. [Epub ahead of print]


Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.

Kobayashi K, Shihoya W, Nishizawa T, Kadji FMN, Aoki J, Inoue A, Nureki O.

Nat Struct Mol Biol. 2020 Mar;27(3):274-280. doi: 10.1038/s41594-020-0386-8. Epub 2020 Mar 9.


[A Case of Pancreatic Head Cancer after Esophagectomy and Gastrectomy Treated with Pancreatoduodenectomy].

Sugimoto T, Komatsu H, Nishizawa Y, Inoue A, Miyazaki Y, Komori T, Motoori M, Tomokuni A, Fujitani K, Iwase K.

Gan To Kagaku Ryoho. 2019 Dec;46(13):2464-2466. Japanese.


[Two Cases of Intraductal Papillary Neoplasm of the Bile Duct(IPNB)Resected with Hepatectomy].

Ikenaga N, Komatsu H, Nishizawa Y, Inoue A, Miyazaki Y, Komori T, Motoori M, Tomokuni A, Fushimi H, Fujitani K, Iwase K.

Gan To Kagaku Ryoho. 2019 Dec;46(13):2398-2400. Japanese.


The Association between Unit-level Workplace Social Capital and Intention to Leave Among Employees in Health Care Settings: A Cross-sectional Multi-level Study.

Iida M, Watanabe K, Ando E, Tsuno K, Inoue A, Kurioka S, Kawakami N.

J Occup Environ Med. 2020 Mar 5. doi: 10.1097/JOM.0000000000001847. [Epub ahead of print]


Membrane Phospholipid Analogues as Molecular Rulers to Probe the Position of the Hydrophobic Contact Point of Lysophospholipid Ligands on the Surface of G-Protein-Coupled Receptor during Membrane Approach.

Sayama M, Uwamizu A, Otani Y, Inoue A, Aoki J, Sekijima M, Ohwada T.

Biochemistry. 2020 Mar 24;59(11):1173-1201. doi: 10.1021/acs.biochem.0c00061. Epub 2020 Mar 10.


Combined Impact of Physical Frailty and Social Isolation on Rate of Falls in Older Adults.

Hayashi T, Umegaki H, Makino T, Huang CH, Inoue A, Shimada H, Kuzuya M.

J Nutr Health Aging. 2020;24(3):312-318. doi: 10.1007/s12603-020-1316-5.


Clinical utility of new three-dimensional model using a zero-echo-time sequence in endoscopic endonasal transsphenoidal surgery.

Inoue A, Kohno S, Nishida N, Suehiro S, Matsumoto S, Nishikawa M, Ozaki S, Nakamura Y, Shigekawa S, Watanabe H, Senba H, Matsuura B, Ohnishi T, Kunieda T.

Clin Neurol Neurosurg. 2020 Mar;190:105743. doi: 10.1016/j.clineuro.2020.105743. Epub 2020 Feb 21.


A Japanese lung cancer registry study on demographics and treatment modalities in medically treated patients.

Sekine I, Shintani Y, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K, Dosaka-Akita H, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I.

Cancer Sci. 2020 Feb 26. doi: 10.1111/cas.14368. [Epub ahead of print]


Naturally shrunk visceral artery aneurysms by stenting for the superior mesenteric artery occlusion.

Inoue A, Ohta S, Imai Y, Murakami Y, Tomozawa Y, Sonoda A, Nitta N.

Minim Invasive Ther Allied Technol. 2020 Feb 26:1-5. doi: 10.1080/13645706.2020.1732426. [Epub ahead of print]


[Mental health and suicide prevention during disasters].

Orui M, Tanaka E, Maeda M, Yagi J, Kondo K, Nomura K, Ito H, Ohira T, Inoue A, Tsutsumi A.

Nihon Koshu Eisei Zasshi. 2020;67(2):101-110. doi: 10.11236/jph.67.2_101. Japanese. No abstract available.


miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells.

Morimoto Y, Mizushima T, Wu X, Okuzaki D, Yokoyama Y, Inoue A, Hata T, Hirose H, Qian Y, Wang J, Miyoshi N, Takahashi H, Haraguchi N, Matsuda C, Doki Y, Mori M, Yamamoto H.

Br J Cancer. 2020 Feb 18. doi: 10.1038/s41416-020-0758-1. [Epub ahead of print]


trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.

Hirata Y, Inoue A, Suzuki S, Takahashi M, Matsui R, Kono N, Noguchi T, Matsuzawa A.

Sci Rep. 2020 Feb 17;10(1):2743. doi: 10.1038/s41598-020-59636-6.


Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells.

Chen Z, Yin Q, Inoue A, Zhang C, Zhang Y.

Sci Adv. 2019 Dec 20;5(12):eaay7246. doi: 10.1126/sciadv.aay7246. eCollection 2019 Dec.


Met-PET uptake index for total tumor resection: identification of 11C-methionine uptake index as a goal for total tumor resection including infiltrating tumor cells in glioblastoma.

Inoue A, Ohnishi T, Kohno S, Ohue S, Nishikawa M, Suehiro S, Matsumoto S, Ozaki S, Fukushima M, Kurata M, Kitazawa R, Shigekawa S, Watanabe H, Kunieda T.

Neurosurg Rev. 2020 Feb 15. doi: 10.1007/s10143-020-01258-7. [Epub ahead of print]


Gadolinium causes M1 and M2 microglial apoptosis after intracerebral haemorrhage and exerts acute neuroprotective effects.

Ohnishi M, Kai T, Shimizu Y, Yano Y, Urabe Y, Tasaka S, Akagi M, Yamaguchi Y, Inoue A.

J Pharm Pharmacol. 2020 Feb 9. doi: 10.1111/jphp.13235. [Epub ahead of print]


Occupational stress and the risk of turnover: a large prospective cohort study of employees in Japan.

Kachi Y, Inoue A, Eguchi H, Kawakami N, Shimazu A, Tsutsumi A.

BMC Public Health. 2020 Feb 4;20(1):174. doi: 10.1186/s12889-020-8289-5.


The association between health-related quality of life and achievement of personalized symptom goal.

Tagami K, Kawaguchi T, Miura T, Yamaguchi T, Matsumoto Y, Watanabe YS, Uehara Y, Okizaki A, Inoue A, Morita T, Kinoshita H.

Support Care Cancer. 2020 Jan 22. doi: 10.1007/s00520-020-05316-0. [Epub ahead of print]


Epithelioid glioblastoma presenting as multicentric glioma: A case report and review of the literature.

Kohno D, Inoue A, Fukushima M, Aki T, Matsumoto S, Suehiro S, Nishikawa M, Ozaki S, Shigekawa S, Watanabe H, Kitazawa R, Kunieda T.

Surg Neurol Int. 2020 Jan 17;11:8. doi: 10.25259/SNI_544_2019. eCollection 2020.


Structural insight into small molecule action on Frizzleds.

Kozielewicz P, Turku A, Bowin CF, Petersen J, Valnohova J, Cañizal MCA, Ono Y, Inoue A, Hoffmann C, Schulte G.

Nat Commun. 2020 Jan 21;11(1):414. doi: 10.1038/s41467-019-14149-3.


Angiopoietin-1/Tie-2 signal after focal traumatic brain injury is potentiated by BQ788, an ETB receptor antagonist, in the mouse cerebrum: Involvement in recovery of blood-brain barrier function.

Michinaga S, Tanabe A, Nakaya R, Fukutome C, Inoue A, Iwane A, Minato Y, Tujiuchi Y, Miyake D, Mizuguchi H, Koyama Y.

J Neurochem. 2020 Jan 19. doi: 10.1111/jnc.14957. [Epub ahead of print]


Structure of the neurotensin receptor 1 in complex with β-arrestin 1.

Huang W, Masureel M, Qu Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK.

Nature. 2020 Mar;579(7798):303-308. doi: 10.1038/s41586-020-1953-1. Epub 2020 Jan 16.


Prognostic significance of immunohistochemical subtypes based on the stage of B-cell differentiation in primary CNS lymphoma.

Inoue A, Ohnishi T, Kohno S, Matsumoto S, Nishikawa M, Ohue S, Ozaki S, Suehiro S, Kurata M, Fukushima M, Kitazawa R, Shigekawa S, Watanabe H, Kunieda T.

Int J Clin Exp Pathol. 2019 Apr 1;12(4):1457-1467. eCollection 2019.


Activation of the GLP-1 receptor by a non-peptidic agonist.

Zhao P, Liang YL, Belousoff MJ, Deganutti G, Fletcher MM, Willard FS, Bell MG, Christe ME, Sloop KW, Inoue A, Truong TT, Clydesdale L, Furness SGB, Christopoulos A, Wang MW, Miller LJ, Reynolds CA, Danev R, Sexton PM, Wootten D.

Nature. 2020 Jan;577(7790):432-436. doi: 10.1038/s41586-019-1902-z. Epub 2020 Jan 8.


The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.

Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J, Iwata S.

Structure. 2019 Dec 21. pii: S0969-2126(19)30442-3. doi: 10.1016/j.str.2019.12.003. [Epub ahead of print]


Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE.

Br J Pharmacol. 2020 Apr;177(8):1898-1916. doi: 10.1111/bph.14960. Epub 2020 Feb 11.


PLF-1 (Proliferin-1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia.

Hu L, Huang Z, Ishii H, Wu H, Suzuki S, Inoue A, Kim W, Jiang H, Li X, Zhu E, Piao L, Zhao G, Lei Y, Okumura K, Shi GP, Murohara T, Kuzuya M, Cheng XW.

J Am Heart Assoc. 2019 Dec 17;8(24):e005886. doi: 10.1161/JAHA.117.005886. Epub 2019 Dec 16.


Loss of Ikbkap/Elp1 in mouse oocytes causes spindle disorganization, developmental defects in preimplantation embryos and impaired female fertility.

Yang KT, Inoue A, Lee YJ, Jiang CL, Lin FJ.

Sci Rep. 2019 Dec 11;9(1):18875. doi: 10.1038/s41598-019-55090-1.


RBM10 regulates centriole duplication in HepG2 cells by ectopically assembling PLK4-STIL complexes in the nucleus.

Kunimoto H, Inoue A, Kojima H, Yang J, Zhao H, Tsuruta D, Nakajima K.

Genes Cells. 2020 Feb;25(2):100-110. doi: 10.1111/gtc.12741. Epub 2020 Jan 20.


3D Vessel Image Reconstruction by MDCT for Surgical Indication and Timing of Strangulating Small Bowel Obstructions.

Murata M, Hiraki M, Hagiwara A, Sawami H, Suzuki R, Fukunaga H, Tanaka N, Inoue A, Takahashi H, Morita S.

World J Surg. 2020 Apr;44(4):1105-1112. doi: 10.1007/s00268-019-05310-6.


Application of Colloidal Dispersions of Bioshell Calcium Oxide (BiSCaO) for Disinfection.

Sato Y, Ohata H, Inoue A, Ishihara M, Nakamura S, Fukuda K, Takayama T, Murakami K, Hiruma S, Yokoe H.

Polymers (Basel). 2019 Dec 2;11(12). pii: E1991. doi: 10.3390/polym11121991.


Phase II study of S-1 in patients with previously-treated invasive thymoma and thymic carcinoma: North Japan lung cancer study group trial 1203.

Tsukita Y, Inoue A, Sugawara S, Kuyama S, Nakagawa T, Harada D, Tanaka H, Watanabe K, Mori Y, Harada T, Hino T, Fujii M, Ichinose M.

Lung Cancer. 2020 Jan;139:89-93. doi: 10.1016/j.lungcan.2019.10.016. Epub 2019 Oct 18.


Factors Associated With Regorafenib Adherence With Metastatic Colorectal Cancer.

Kawakami K, Wakatsuki T, Soejima A, Kobayashi K, Yokokawa T, Aoyama T, Suzuki K, Suenaga M, Yamaguchi K, Inoue A, Machida Y, Hama T.

Patient Prefer Adherence. 2019 Oct 15;13:1745-1750. doi: 10.2147/PPA.S217835. eCollection 2019.


Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study.

Hosomi Y, Morita S, Sugawara S, Kato T, Fukuhara T, Gemma A, Takahashi K, Fujita Y, Harada T, Minato K, Takamura K, Hagiwara K, Kobayashi K, Nukiwa T, Inoue A; North-East Japan Study Group.

J Clin Oncol. 2020 Jan 10;38(2):115-123. doi: 10.1200/JCO.19.01488. Epub 2019 Nov 4.


Acyl-CoA synthetase 6 regulates long-chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice.

Shishikura K, Kuroha S, Matsueda S, Iseki H, Matsui T, Inoue A, Arita M.

FASEB J. 2019 Dec;33(12):14194-14203. doi: 10.1096/fj.201901074R. Epub 2019 Oct 25.


Cathepsin S-Mediated Negative Regulation of Wnt5a/SC35 Activation Contributes to Ischemia-Induced Neovascularization in Aged Mice.

Xu W, Yu C, Piao L, Inoue A, Wang H, Meng X, Li X, Cui L, Umegaki H, Shi GP, Murohara T, Kuzuya M, Cheng XW.

Circ J. 2019 Nov 25;83(12):2537-2546. doi: 10.1253/circj.CJ-19-0325. Epub 2019 Oct 24.


Organizational justice and illness reporting among Japanese employees with chronic diseases.

Eguchi H, Tsutsumi A, Inoue A, Kachi Y.

PLoS One. 2019 Oct 21;14(10):e0223595. doi: 10.1371/journal.pone.0223595. eCollection 2019.


High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node.

Simmons S, Sasaki N, Umemoto E, Uchida Y, Fukuhara S, Kitazawa Y, Okudaira M, Inoue A, Tohya K, Aoi K, Aoki J, Mochizuki N, Matsuno K, Takeda K, Miyasaka M, Ishii M.

Elife. 2019 Oct 1;8. pii: e41239. doi: 10.7554/eLife.41239.


Computed tomography diagnosis of transomental hernia.

Inoue A, Furukawa A.

Jpn J Radiol. 2019 Dec;37(12):860-861. doi: 10.1007/s11604-019-00879-3. Epub 2019 Sep 21. No abstract available.


E-cadherin-Fc chimera protein matrix enhances cancer stem-like properties and induces mesenchymal features in colon cancer cells.

Qian Y, Wu X, Yokoyama Y, Okuzaki D, Taguchi M, Hirose H, Wang J, Hata T, Inoue A, Hiraki M, Ohtsuka M, Takahashi H, Haraguchi N, Mizushima T, Tanaka S, Mori M, Yamamoto H.

Cancer Sci. 2019 Nov;110(11):3520-3532. doi: 10.1111/cas.14193. Epub 2019 Sep 30.


Spatial regulation of GPR64/ADGRG2 signaling by β-arrestins and GPCR kinases.

Azimzadeh P, Talamantez-Lyburn SC, Chang KT, Inoue A, Balenga N.

Ann N Y Acad Sci. 2019 Nov;1456(1):26-43. doi: 10.1111/nyas.14227. Epub 2019 Sep 9.


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