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Protection induced by malaria virus-like particles containing codon-optimized AMA-1 of Plasmodium berghei.

Lee DH, Chu KB, Kang HJ, Lee SH, Chopra M, Choi HJ, Moon EK, Inn KS, Quan FS.

Malar J. 2019 Dec 3;18(1):394. doi: 10.1186/s12936-019-3017-2.


Vaccine Efficacy Induced by 2009 Pandemic H1N1 Virus-Like Particles Differs from that Induced by Split Influenza Virus.

Lee GJ, Chu KB, Inn KS, Moon EK, Quan FS.

Immunol Invest. 2019 Nov 27:1-13. doi: 10.1080/08820139.2019.1694539. [Epub ahead of print]


Immunostimulatory effects of polysaccharides isolated from young barley leaves (Hordeum vulgare L.) with dual activation of Th1 and Th2 in splenic T cells and cyclophosphamide-induced immunosuppressed mice.

Han HS, Shin JS, Song YR, Rhee YK, Cho CW, Ryu JH, Inn KS, Hong HD, Lee KT.

Int J Biol Macromol. 2019 Nov 12. pii: S0141-8130(19)36527-4. doi: 10.1016/j.ijbiomac.2019.10.062. [Epub ahead of print]


Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015.

Kim YS, Aigerim A, Park U, Kim Y, Rhee JY, Choi JP, Park WB, Park SW, Kim Y, Lim DG, Inn KS, Hwang ES, Choi MS, Shin HS, Cho NH.

Emerg Infect Dis. 2019 Jun;25(6):1161-1168. doi: 10.3201/eid2506.181722. Epub 2019 Jun 17.


Human Respiratory Syncytial Virus NS 1 Targets TRIM25 to Suppress RIG-I Ubiquitination and Subsequent RIG-I-Mediated Antiviral Signaling.

Ban J, Lee NR, Lee NJ, Lee JK, Quan FS, Inn KS.

Viruses. 2018 Dec 14;10(12). pii: E716. doi: 10.3390/v10120716.


A Novel and Selective p38 Mitogen-Activated Protein Kinase Inhibitor Attenuates LPS-Induced Neuroinflammation in BV2 Microglia and a Mouse Model.

Gee MS, Kim SW, Kim N, Lee SJ, Oh MS, Jin HK, Bae JS, Inn KS, Kim NJ, Lee JK.

Neurochem Res. 2018 Dec;43(12):2362-2371. doi: 10.1007/s11064-018-2661-1. Epub 2018 Oct 16.


Activation of RIG-I-Mediated Antiviral Signaling Triggers Autophagy Through the MAVS-TRAF6-Beclin-1 Signaling Axis.

Lee NR, Ban J, Lee NJ, Yi CM, Choi JY, Kim H, Lee JK, Seong J, Cho NH, Jung JU, Inn KS.

Front Immunol. 2018 Sep 12;9:2096. doi: 10.3389/fimmu.2018.02096. eCollection 2018. Review.


A Type I Interferon and IL-10 Induced by Orientia tsutsugamushi Infection Suppresses Antigen-Specific T Cells and Their Memory Responses.

Min CK, Kim HI, Ha NY, Kim Y, Kwon EK, Yen NTH, Youn JI, Jeon YK, Inn KS, Choi MS, Cho NH.

Front Immunol. 2018 Sep 4;9:2022. doi: 10.3389/fimmu.2018.02022. eCollection 2018.


Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway.

Lee NR, Choi JY, Yoon IH, Lee JK, Inn KS.

Cell Immunol. 2018 Oct;332:94-100. doi: 10.1016/j.cellimm.2018.08.004. Epub 2018 Aug 7.


Preclinical Evaluation of In Vitro and In Vivo Antiviral Activities of KCT-01, a New Herbal Formula against Hepatitis B Virus.

Kim H, Jang E, Kim SY, Choi JY, Lee NR, Kim DS, Lee KT, Inn KS, Kim BJ, Lee JH.

Evid Based Complement Alternat Med. 2018 Jul 4;2018:1073509. doi: 10.1155/2018/1073509. eCollection 2018.


Piperlongumine inhibits neuroinflammation via regulating NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells.

Kim N, Do J, Bae JS, Jin HK, Kim JH, Inn KS, Oh MS, Lee JK.

J Pharmacol Sci. 2018 Jun;137(2):195-201. doi: 10.1016/j.jphs.2018.06.004. Epub 2018 Jun 18.


Reduction of soluble dipeptidyl peptidase 4 levels in plasma of patients infected with Middle East respiratory syndrome coronavirus.

Inn KS, Kim Y, Aigerim A, Park U, Hwang ES, Choi MS, Kim YS, Cho NH.

Virology. 2018 May;518:324-327. doi: 10.1016/j.virol.2018.03.015. Epub 2018 Mar 26.


Synthetic 3',4'-Dihydroxyflavone Exerts Anti-Neuroinflammatory Effects in BV2 Microglia and a Mouse Model.

Kim N, Yoo HS, Ju YJ, Oh MS, Lee KT, Inn KS, Kim NJ, Lee JK.

Biomol Ther (Seoul). 2018 Mar 1;26(2):210-217. doi: 10.4062/biomolther.2018.008.


Phytotherapeutic Activities of Sanguisorba officinalis and its Chemical Constituents: A Review.

Jang E, Inn KS, Jang YP, Lee KT, Lee JH.

Am J Chin Med. 2018;46(2):299-318. doi: 10.1142/S0192415X18500155. Epub 2018 Feb 12. Review.


Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages.

Han HS, Jang E, Shin JS, Inn KS, Lee JH, Park G, Jang YP, Lee KT.

Evid Based Complement Alternat Med. 2017;2017:7383104. doi: 10.1155/2017/7383104. Epub 2017 Nov 29.


New determination of the 229Th half-life.

Essex RM, Mann JL, Collé R, Laureano-Perez L, Bennett ME, Dion H, Fitzgerald R, Gaffney AM, Gourgiotis A, Hubert A, Inn KGW, Kinman WS, Lamont SP, Steiner R, Williams RW.

J Radioanal Nucl Chem. 2018;318. doi: 10.1007/s10967-018-6032-9.


Identification of actin as a direct proteomic target of berberine using an affinity-based chemical probe and elucidation of its modulatory role in actin assembly.

Yi CM, Yu J, Kim H, Lee NR, Kim SW, Lee NJ, Lee J, Seong J, Kim NJ, Inn KS.

Chem Commun (Camb). 2017 Jun 27;53(52):7045-7047. doi: 10.1039/c7cc02789c.


An Effective Antiviral Approach Targeting Hepatitis B Virus with NJK14047, a Novel and Selective Biphenyl Amide p38 Mitogen-Activated Protein Kinase Inhibitor.

Kim SY, Kim H, Kim SW, Lee NR, Yi CM, Heo J, Kim BJ, Kim NJ, Inn KS.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00214-17. doi: 10.1128/AAC.00214-17. Print 2017 Aug.


Corrigendum: Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection.

Ahn YH, Park S, Choi JJ, Park BK, Rhee KH, Kang E, Ahn S, Lee CH, Lee JS, Inn KS, Cho ML, Park SH, Park K, Park HJ, Lee JH, Park JW, Kwon NH, Shim H, Han BW, Kim P, Lee JY, Jeon Y, Huh JW, Jin M, Kim S.

Nat Microbiol. 2017 Jan 23;2:17015. doi: 10.1038/nmicrobiol.2017.15. No abstract available.


Evaluation of antitumor activity of Artemisia capillaris extract against hepatocellular carcinoma through the inhibition of IL-6/STAT3 signaling axis.

Jang E, Kim SY, Lee NR, Yi CM, Hong DR, Lee WS, Kim JH, Lee KT, Kim BJ, Lee JH, Inn KS.

Oncol Rep. 2017 Jan;37(1):526-532. doi: 10.3892/or.2016.5283. Epub 2016 Nov 29.


TPL2 Is an Oncogenic Driver in Keratocanthoma and Squamous Cell Carcinoma.

Lee JH, Lee JH, Lee SH, Do SI, Cho SD, Forslund O, Inn KS, Lee JS, Deng FM, Melamed J, Jung JU, Jeong JH.

Cancer Res. 2016 Nov 15;76(22):6712-6722. doi: 10.1158/0008-5472.CAN-15-3274. Epub 2016 Aug 8.


Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection.

Ahn YH, Park S, Choi JJ, Park BK, Rhee KH, Kang E, Ahn S, Lee CH, Lee JS, Inn KS, Cho ML, Park SH, Park K, Park HJ, Lee JH, Park JW, Kwon NH, Shim H, Han BW, Kim P, Lee JY, Jeon Y, Huh JW, Jin M, Kim S.

Nat Microbiol. 2016 Oct 17;2:16191. doi: 10.1038/nmicrobiol.2016.191. Erratum in: Nat Microbiol. 2017 Jan 23;2:17015.


Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner.

Kim H, Choi MS, Inn KS, Kim BJ.

Sci Rep. 2016 Jul 1;6:28896. doi: 10.1038/srep28896.


A novel p38 mitogen activated protein kinase (MAPK) specific inhibitor suppresses respiratory syncytial virus and influenza A virus replication by inhibiting virus-induced p38 MAPK activation.

Choi MS, Heo J, Yi CM, Ban J, Lee NJ, Lee NR, Kim SW, Kim NJ, Inn KS.

Biochem Biophys Res Commun. 2016 Aug 26;477(3):311-6. doi: 10.1016/j.bbrc.2016.06.111. Epub 2016 Jun 23.


Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity.

Min CK, Cheon S, Ha NY, Sohn KM, Kim Y, Aigerim A, Shin HM, Choi JY, Inn KS, Kim JH, Moon JY, Choi MS, Cho NH, Kim YS.

Sci Rep. 2016 May 5;6:25359. doi: 10.1038/srep25359.



Fitzgerald R, Inn KGW, Horgan C.

J Radioanal Nucl Chem. 2016 Mar;307(3):2521-2528. doi: 10.1007/s10967-015-4565-8. Epub 2015 Oct 27.


Identification of novel estrogen receptor (ER) agonists that have additional and complementary anti-cancer activities via ER-independent mechanism.

Kim T, Kim HI, An JY, Lee J, Lee NR, Heo J, Kim JE, Yu J, Lee YS, Inn KS, Kim NJ.

Bioorg Med Chem Lett. 2016 Apr 1;26(7):1844-8. doi: 10.1016/j.bmcl.2016.01.089. Epub 2016 Feb 13.


A versatile approach to flavones via a one-pot Pd(II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones.

Lee J, Yu J, Son SH, Heo J, Kim T, An JY, Inn KS, Kim NJ.

Org Biomol Chem. 2016 Jan 14;14(2):777-784. doi: 10.1039/c5ob01911g.


A Survey of Therapeutic Effects of Artemisia capillaris in Liver Diseases.

Jang E, Kim BJ, Lee KT, Inn KS, Lee JH.

Evid Based Complement Alternat Med. 2015;2015:728137. doi: 10.1155/2015/728137. Epub 2015 Aug 20. Review.


Regulation of MDA5-MAVS Antiviral Signaling Axis by TRIM25 through TRAF6-Mediated NF-κB Activation.

Lee NR, Kim HI, Choi MS, Yi CM, Inn KS.

Mol Cells. 2015 Sep;38(9):759-64. doi: 10.14348/molcells.2015.0047. Epub 2015 Aug 21.


Synthesis and biological evaluation of N-cyclopropylbenzamide-benzophenone hybrids as novel and selective p38 mitogen activated protein kinase (MAPK) inhibitors.

Heo J, Shin H, Lee J, Kim T, Inn KS, Kim NJ.

Bioorg Med Chem Lett. 2015 Sep 1;25(17):3694-8. doi: 10.1016/j.bmcl.2015.06.036. Epub 2015 Jun 16.


NJK14013, a novel synthetic estrogen receptor-α agonist, exhibits estrogen receptor-independent, tumor cell-specific cytotoxicity.

Kim HI, Kim T, Kim JE, Lee J, Heo J, Lee NR, Kim NJ, Inn KS.

Int J Oncol. 2015 Jul;47(1):280-6. doi: 10.3892/ijo.2015.3002. Epub 2015 May 12.


Inhibition of respiratory syncytial virus replication and virus-induced p38 kinase activity by berberine.

Shin HB, Choi MS, Yi CM, Lee J, Kim NJ, Inn KS.

Int Immunopharmacol. 2015 Jul;27(1):65-8. doi: 10.1016/j.intimp.2015.04.045. Epub 2015 May 2.


Upregulation of endoplasmic reticulum stress and reactive oxygen species by naturally occurring mutations in hepatitis B virus core antigen.

Lee H, Kim H, Lee SA, Won YS, Kim HI, Inn KS, Kim BJ.

J Gen Virol. 2015 Jul;96(Pt 7):1850-4. doi: 10.1099/vir.0.000134. Epub 2015 Mar 31.


Male-specific hepatitis B virus large surface protein variant W4P potentiates tumorigenicity and induces gender disparity.

Lee SA, Kim H, Won YS, Seok SH, Na Y, Shin HB, Inn KS, Kim BJ.

Mol Cancer. 2015 Feb 3;14:23. doi: 10.1186/s12943-015-0303-7.


Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.

Shi M, Cho H, Inn KS, Yang A, Zhao Z, Liang Q, Versteeg GA, Amini-Bavil-Olyaee S, Wong LY, Zlokovic BV, Park HS, García-Sastre A, Jung JU.

Nat Commun. 2014 Sep 5;5:4820. doi: 10.1038/ncomms5820.


Inhibition of estrogen signaling through depletion of estrogen receptor alpha by ursolic acid and betulinic acid from Prunella vulgaris var. lilacina.

Kim HI, Quan FS, Kim JE, Lee NR, Kim HJ, Jo SJ, Lee CM, Jang DS, Inn KS.

Biochem Biophys Res Commun. 2014 Aug 22;451(2):282-7. doi: 10.1016/j.bbrc.2014.07.115. Epub 2014 Aug 1.


Comparative study of non-invasive methods for assessing Daphnia magna embryo toxicity.

Stensberg MC, Zeitchek MA, Inn K, McLamore ES, Porterfield DM, Sepúlveda MS.

Environ Sci Pollut Res Int. 2014 Sep;21(18):10803-14. doi: 10.1007/s11356-014-3058-6. Epub 2014 Jun 4.


Tumor-suppressive effect of a telomerase-derived peptide by inhibiting hypoxia-induced HIF-1α-VEGF signaling axis.

Kim BK, Kim BR, Lee HJ, Lee SA, Kim BJ, Kim H, Won YS, Shon WJ, Lee NR, Inn KS, Kim BJ.

Biomaterials. 2014 Mar;35(9):2924-33. doi: 10.1016/j.biomaterials.2013.12.077. Epub 2014 Jan 8.


A pandemic H1N1 influenza virus-like particle vaccine induces cross-protection in mice.

Inn KS, Lee GJ, Quan FS.

Immunol Invest. 2014;43(3):236-54. doi: 10.3109/08820139.2013.864665. Epub 2013 Dec 19.


Antiviral activity of carnosic acid against respiratory syncytial virus.

Shin HB, Choi MS, Ryu B, Lee NR, Kim HI, Choi HE, Chang J, Lee KT, Jang DS, Inn KS.

Virol J. 2013 Oct 8;10:303. doi: 10.1186/1743-422X-10-303.


The product of Kaposi's sarcoma-associated herpesvirus immediate early gene K4.2 regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1.

Wong LY, Brulois K, Toth Z, Inn KS, Lee SH, O'Brien K, Lee H, Gao SJ, Cesarman E, Ensser A, Jung JU.

J Virol. 2013 Nov;87(22):12069-79. doi: 10.1128/JVI.01900-13. Epub 2013 Aug 28.


Heat shock protein-mediated cell penetration and cytosolic delivery of macromolecules by a telomerase-derived peptide vaccine.

Lee SA, Kim BR, Kim BK, Kim DW, Shon WJ, Lee NR, Inn KS, Kim BJ.

Biomaterials. 2013 Oct;34(30):7495-505. doi: 10.1016/j.biomaterials.2013.06.015. Epub 2013 Jul 1.


Negative regulation of RIG-I-mediated antiviral signaling by TRK-fused gene (TFG) protein.

Lee NR, Shin HB, Kim HI, Choi MS, Inn KS.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):168-72. doi: 10.1016/j.bbrc.2013.06.061. Epub 2013 Jun 26.


Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.

Maazi H, Singh AK, Speak AO, Lombardi V, Lam J, Khoo B, Inn KS, Sharpe AH, Jung JU, Akbari O.

PLoS One. 2013;8(3):e59599. doi: 10.1371/journal.pone.0059599. Epub 2013 Mar 15.


The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.

Versteeg GA, Rajsbaum R, Sánchez-Aparicio MT, Maestre AM, Valdiviezo J, Shi M, Inn KS, Fernandez-Sesma A, Jung J, García-Sastre A.

Immunity. 2013 Feb 21;38(2):384-98. doi: 10.1016/j.immuni.2012.11.013.


Determination of 239Pu/240Pu isotopic ratio by high-resolution alpha-particle spectrometry using the ADAM program.

Pöllänen R, Siiskonen T, Ihantola S, Toivonen H, Pelikan A, Inn K, La Rosa J, Bene BJ.

Appl Radiat Isot. 2012 Apr;70(4):733-9. doi: 10.1016/j.apradiso.2011.12.026. Epub 2011 Dec 22.


Inhibition of RIG-I-mediated signaling by Kaposi's sarcoma-associated herpesvirus-encoded deubiquitinase ORF64.

Inn KS, Lee SH, Rathbun JY, Wong LY, Toth Z, Machida K, Ou JH, Jung JU.

J Virol. 2011 Oct;85(20):10899-904. doi: 10.1128/JVI.00690-11. Epub 2011 Aug 10.


Emergency radiobioassay preparedness exercises through the NIST radiochemistry intercomparison program.

Nour S, LaRosa J, Inn KG.

Health Phys. 2011 Aug;101(2):170-5. doi: 10.1097/HP.0b013e3182149823.


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