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Items: 11


Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction.

Kain V, Ingle KA, Kabarowski J, Barnes S, Limdi NA, Prabhu SD, Halade GV.

J Mol Cell Cardiol. 2018 May;118:70-80. doi: 10.1016/j.yjmcc.2018.03.004. Epub 2018 Mar 8.


Splenic leukocytes define the resolution of inflammation in heart failure.

Halade GV, Norris PC, Kain V, Serhan CN, Ingle KA.

Sci Signal. 2018 Mar 6;11(520). pii: eaao1818. doi: 10.1126/scisignal.aao1818.


Comprehensive targeted and non-targeted lipidomics analyses in failing and non-failing heart.

Halade GV, Dorbane A, Ingle KA, Kain V, Schmitter JM, Rhourri-Frih B.

Anal Bioanal Chem. 2018 Mar;410(7):1965-1976. doi: 10.1007/s00216-018-0863-7. Epub 2018 Feb 6.


Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology.

Halade GV, Kain V, Ingle KA.

Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H255-H267. doi: 10.1152/ajpheart.00528.2017. Epub 2017 Nov 3.


Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation.

Kain V, Ingle KA, Kachman M, Baum H, Shanmugam G, Rajasekaran NS, Young ME, Halade GV.

Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H160-H169. doi: 10.1152/ajpheart.00297.2017. Epub 2017 Oct 6.


Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing.

Kain V, Liu F, Kozlovskaya V, Ingle KA, Bolisetty S, Agarwal A, Khedkar S, Prabhu SD, Kharlampieva E, Halade GV.

Sci Rep. 2017 Aug 30;7(1):9999. doi: 10.1038/s41598-017-10441-8.


Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healing.

Halade GV, Kain V, Ingle KA, Prabhu SD.

Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H89-H102. doi: 10.1152/ajpheart.00040.2017. Epub 2017 Apr 14.


Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction.

Halade GV, Kain V, Black LM, Prabhu SD, Ingle KA.

Aging (Albany NY). 2016 Oct 18;8(11):2611-2634. doi: 10.18632/aging.101077.


Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation.

Ingle KA, Kain V, Goel M, Prabhu SD, Young ME, Halade GV.

Am J Physiol Heart Circ Physiol. 2015 Dec 1;309(11):H1827-36. doi: 10.1152/ajpheart.00608.2015. Epub 2015 Oct 2.


Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function.

Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M, Halade GV.

J Mol Cell Cardiol. 2015 Jul;84:24-35. doi: 10.1016/j.yjmcc.2015.04.003. Epub 2015 Apr 11.


Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction.

Lopez EF, Kabarowski JH, Ingle KA, Kain V, Barnes S, Crossman DK, Lindsey ML, Halade GV.

Am J Physiol Heart Circ Physiol. 2015 Feb 15;308(4):H269-80. doi: 10.1152/ajpheart.00604.2014. Epub 2014 Dec 5.

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