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Stratifying the mechanical performance of a decellularized xenogeneic tendon graft for anterior cruciate ligament reconstruction as a function of graft diameter: An animal study.

Whitaker S, Edwards JH, Guy S, Ingham E, Herbert A.

Bone Joint Res. 2019 Dec 3;8(11):518-525. doi: 10.1302/2046-3758.811.BJR-2019-0065.R1. eCollection 2019 Nov.


Biomechanical assessment of the stability of osteochondral grafts implanted in porcine and bovine femoral condyles.

Bowland P, Cowie RM, Ingham E, Fisher J, Jennings LM.

Proc Inst Mech Eng H. 2020 Feb;234(2):163-170. doi: 10.1177/0954411919891673. Epub 2019 Dec 4.


Tumor-specific delivery of gemcitabine with activatable liposomes.

Tucci ST, Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Foiret J, Hubbard NE, Borowsky AD, Baikoghli M, Cheng RH, Ferrara KW.

J Control Release. 2019 Sep 10;309:277-288. doi: 10.1016/j.jconrel.2019.07.014. Epub 2019 Jul 10.


Development of a pre-clinical experimental simulation model of the natural porcine knee with appropriate ligamentous constraints.

Liu A, Ingham E, Fisher J, Jennings LM.

PLoS One. 2019 May 14;14(5):e0216872. doi: 10.1371/journal.pone.0216872. eCollection 2019.


Combining activatable nanodelivery with immunotherapy in a murine breast cancer model.

Kheirolomoom A, Silvestrini MT, Ingham ES, Mahakian LM, Tam SM, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Ferrara KW.

J Control Release. 2019 Jun 10;303:42-54. doi: 10.1016/j.jconrel.2019.04.008. Epub 2019 Apr 9.


Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.

Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Bahador M, Bernatz S, Braun Y, Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam S, Tepper CG, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R, Thorsen F.

Acta Neuropathol Commun. 2019 Apr 10;7(1):55. doi: 10.1186/s40478-019-0712-8.


Decellularisation affects the strain rate dependent and dynamic mechanical properties of a xenogeneic tendon intended for anterior cruciate ligament replacement.

Edwards JH, Ingham E, Herbert A.

J Mech Behav Biomed Mater. 2019 Mar;91:18-23. doi: 10.1016/j.jmbbm.2018.11.023. Epub 2018 Nov 26.


A Scalable Method for Squalenoylation and Assembly of Multifunctional 64Cu-Labeled Squalenoylated Gemcitabine Nanoparticles.

Tucci ST, Seo JW, Kakwere H, Kheirolomoom A, Ingham ES, Mahakian LM, Tam S, Tumbale S, Baikoghli M, Cheng RH, Ferrara KW.

Nanotheranostics. 2018 Sep 5;2(4):387-402. doi: 10.7150/ntno.26969. eCollection 2018.


Unimicellar hyperstars as multi-antigen cancer nanovaccines displaying clustered epitopes of immunostimulating peptides.

Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS, Ferrara KW.

Biomater Sci. 2018 Nov 1;6(11):2850-2858. doi: 10.1039/c8bm00891d. Epub 2018 Sep 19.


Development of a preclinical natural porcine knee simulation model for the tribological assessment of osteochondral grafts in vitro.

Bowland P, Ingham E, Fisher J, Jennings LM.

J Biomech. 2018 Aug 22;77:91-98. doi: 10.1016/j.jbiomech.2018.06.014. Epub 2018 Jul 10.


Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation.

Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW.

Theranostics. 2018 Jun 7;8(13):3611-3628. doi: 10.7150/thno.25613. eCollection 2018.


On the design and efficacy assessment of self-assembling peptide-based hydrogel-glycosaminoglycan mixtures for potential repair of early stage cartilage degeneration.

Barco A, Ingham E, Fisher J, Fermor H, Davies RPW.

J Pept Sci. 2018 Aug;24(8-9):e3114. doi: 10.1002/psc.3114. Epub 2018 Jul 18.


CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols.

Seo JW, Tavaré R, Mahakian LM, Silvestrini MT, Tam S, Ingham ES, Salazar FB, Borowsky AD, Wu AM, Ferrara KW.

Clin Cancer Res. 2018 Oct 15;24(20):4976-4987. doi: 10.1158/1078-0432.CCR-18-0261. Epub 2018 Jul 2.


Simple geometry tribological study of osteochondral graft implantation in the knee.

Bowland P, Ingham E, Fisher J, Jennings LM.

Proc Inst Mech Eng H. 2018 Mar;232(3):249-256. doi: 10.1177/0954411917751560. Epub 2018 Jan 27.


In vitro biomechanical and hydrodynamic characterisation of decellularised human pulmonary and aortic roots.

Desai A, Vafaee T, Rooney P, Kearney JN, Berry HE, Ingham E, Fisher J, Jennings LM.

J Mech Behav Biomed Mater. 2018 Mar;79:53-63. doi: 10.1016/j.jmbbm.2017.09.019. Epub 2017 Sep 14.


Development and characterisation of a large diameter decellularised vascular allograft.

Aldridge A, Desai A, Owston H, Jennings LM, Fisher J, Rooney P, Kearney JN, Ingham E, Wilshaw SP.

Cell Tissue Bank. 2018 Sep;19(3):287-300. doi: 10.1007/s10561-017-9673-y. Epub 2017 Nov 29.


Toward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.

Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS, Ferrara KW.

Bioconjug Chem. 2017 Nov 15;28(11):2756-2771. doi: 10.1021/acs.bioconjchem.7b00502. Epub 2017 Oct 13.


Development and characterisation of a low-concentration sodium dodecyl sulphate decellularised porcine dermis.

Helliwell JA, Thomas DS, Papathanasiou V, Homer-Vanniasinkam S, Desai A, Jennings LM, Rooney P, Kearney JN, Ingham E.

J Tissue Eng. 2017 Aug 3;8:2041731417724011. doi: 10.1177/2041731417724011. eCollection 2017 Jan-Dec.


The effects of irradiation dose and storage time following treatment on the viscoelastic properties of decellularised porcine super flexor tendon.

Herbert A, Edwards JH, Jones GL, Ingham E, Fisher J.

J Biomech. 2017 May 24;57:157-160. doi: 10.1016/j.jbiomech.2017.04.005. Epub 2017 Apr 19.


Dynamic contrast enhanced MRI detects changes in vascular transport rate constants following treatment with thermally-sensitive liposomal doxorubicin.

Fite BZ, Kheirolomoom A, Foiret JL, Seo JW, Mahakian LM, Ingham ES, Tam SM, Borowsky AD, Curry FE, Ferrara KW.

J Control Release. 2017 Jun 28;256:203-213. doi: 10.1016/j.jconrel.2017.04.007. Epub 2017 Apr 7.


Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.

Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW.

JCI Insight. 2017 Mar 23;2(6):e90521. doi: 10.1172/jci.insight.90521.


Feasibility of quantitative contrast ultrasound imaging of bladder tumors in dogs.

Pollard RE, Watson KD, Hu X, Ingham E, Ferrara KW.

Can Vet J. 2017 Jan;58(1):70-72.


Decellularization of human donor aortic and pulmonary valved conduits using low concentration sodium dodecyl sulfate.

Vafaee T, Thomas D, Desai A, Jennings LM, Berry H, Rooney P, Kearney J, Fisher J, Ingham E.

J Tissue Eng Regen Med. 2018 Feb;12(2):e841-e853. doi: 10.1002/term.2391. Epub 2017 May 12.


In vitro characterization and in vivo ultrasound molecular imaging of nucleolin-targeted microbubbles.

Zhang H, Ingham ES, Gagnon MK, Mahakian LM, Liu J, Foiret JL, Willmann JK, Ferrara KW.

Biomaterials. 2017 Feb;118:63-73. doi: 10.1016/j.biomaterials.2016.11.026. Epub 2016 Nov 21.


Intracellular trafficking of a pH-responsive drug metal complex.

Kheirolomoom A, Ingham ES, Commisso J, Abushaban N, Ferrara KW.

J Control Release. 2016 Dec 10;243:232-242. doi: 10.1016/j.jconrel.2016.10.012. Epub 2016 Oct 13.


Decellularization and Characterization of Porcine Superflexor Tendon: A Potential Anterior Cruciate Ligament Replacement.

Jones G, Herbert A, Berry H, Edwards JH, Fisher J, Ingham E.

Tissue Eng Part A. 2017 Feb;23(3-4):124-134. doi: 10.1089/ten.TEA.2016.0114. Epub 2016 Dec 7.


The effects of irradiation on the biological and biomechanical properties of an acellular porcine superflexor tendon graft for cruciate ligament repair.

Edwards JH, Herbert A, Jones GL, Manfield IW, Fisher J, Ingham E.

J Biomed Mater Res B Appl Biomater. 2017 Nov;105(8):2477-2486. doi: 10.1002/jbm.b.33786. Epub 2016 Sep 23.


Bi-linear mechanical property determination of acellular human patellar tendon grafts for use in anterior cruciate ligament replacement.

Herbert A, Brown C, Rooney P, Kearney J, Ingham E, Fisher J.

J Biomech. 2016 Jun 14;49(9):1607-1612. doi: 10.1016/j.jbiomech.2016.03.041. Epub 2016 Mar 30.


Regional biomechanical and histological characterization of the mitral valve apparatus: Implications for mitral repair strategies.

Roberts N, Morticelli L, Jin Z, Ingham E, Korossis S.

J Biomech. 2016 Aug 16;49(12):2491-501. doi: 10.1016/j.jbiomech.2015.12.042. Epub 2015 Dec 30.


Review of the biomechanics and biotribology of osteochondral grafts used for surgical interventions in the knee.

Bowland P, Ingham E, Jennings L, Fisher J.

Proc Inst Mech Eng H. 2015 Dec;229(12):879-88. doi: 10.1177/0954411915615470. Review.


CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.

Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Silvestrini MT, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Murphy WJ, Ferrara KW.

J Control Release. 2015 Dec 28;220(Pt A):253-264. doi: 10.1016/j.jconrel.2015.10.016. Epub 2015 Oct 22.


Self-assembled 20-nm (64)Cu-micelles enhance accumulation in rat glioblastoma.

Seo JW, Ang J, Mahakian LM, Tam S, Fite B, Ingham ES, Beyer J, Forsayeth J, Bankiewicz KS, Xu T, Ferrara KW.

J Control Release. 2015 Dec 28;220(Pt A):51-60. doi: 10.1016/j.jconrel.2015.09.057. Epub 2015 Oct 5.


Biological, biochemical and biomechanical characterisation of articular cartilage from the porcine, bovine and ovine hip and knee.

Fermor HL, McLure SW, Taylor SD, Russell SL, Williams S, Fisher J, Ingham E.

Biomed Mater Eng. 2015;25(4):381-95. doi: 10.3233/BME-151533.


Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE(-/-) Mice.

Kheirolomoom A, Kim CW, Seo JW, Kumar S, Son DJ, Gagnon MK, Ingham ES, Ferrara KW, Jo H.

ACS Nano. 2015 Sep 22;9(9):8885-97. doi: 10.1021/acsnano.5b02611. Epub 2015 Sep 2.


Tribology studies of the natural knee using an animal model in a new whole joint natural knee simulator.

Liu A, Jennings LM, Ingham E, Fisher J.

J Biomech. 2015 Sep 18;48(12):3004-11. doi: 10.1016/j.jbiomech.2015.07.043. Epub 2015 Aug 11.


A Nondestructive Method to Distinguish the Internal Constituent Architecture of the Intervertebral Discs Using 9.4 Tesla Magnetic Resonance Imaging.

Wijayathunga VN, Ridgway JP, Ingham E, Treanor D, Carey D, Bulpitt A, Magee D, Damion R, Wilcox RK.

Spine (Phila Pa 1976). 2015 Dec;40(24):E1315-22. doi: 10.1097/BRS.0000000000001075.


Non-destructive monitoring of viability in an ex vivo organ culture model of osteochondral tissue.

Elson KM, Fox N, Tipper JL, Kirkham J, Hall RM, Fisher J, Ingham E.

Eur Cell Mater. 2015 Jun 30;29:356-69; discussion 369.


The biological response to nanometre-sized polymer particles.

Liu A, Richards L, Bladen CL, Ingham E, Fisher J, Tipper JL.

Acta Biomater. 2015 Sep;23:38-51. doi: 10.1016/j.actbio.2015.05.016. Epub 2015 May 22.


Ultrasound molecular imaging of tumor angiogenesis with a neuropilin-1-targeted microbubble.

Zhang H, Tam S, Ingham ES, Mahakian LM, Lai CY, Tumbale SK, Teesalu T, Hubbard NE, Borowsky AD, Ferrara KW.

Biomaterials. 2015 Jul;56:104-13. doi: 10.1016/j.biomaterials.2015.03.043. Epub 2015 Apr 16.


Development and characterisation of a decellularised bovine osteochondral biomaterial for cartilage repair.

Fermor HL, Russell SL, Williams S, Fisher J, Ingham E.

J Mater Sci Mater Med. 2015 May;26(5):186. doi: 10.1007/s10856-015-5517-0. Epub 2015 Apr 21.


Comparison of the biomechanical tensile and compressive properties of decellularised and natural porcine meniscus.

Abdelgaied A, Stanley M, Galfe M, Berry H, Ingham E, Fisher J.

J Biomech. 2015 Jun 1;48(8):1389-96. doi: 10.1016/j.jbiomech.2015.02.044. Epub 2015 Feb 26.


The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model.

Seo JW, Mahakian LM, Tam S, Qin S, Ingham ES, Meares CF, Ferrara KW.

Nucl Med Biol. 2015 Feb;42(2):155-63. doi: 10.1016/j.nucmedbio.2014.09.001. Epub 2014 Sep 28.


Development of a terminally sterilised decellularised dermis.

Hogg P, Rooney P, Leow-Dyke S, Brown C, Ingham E, Kearney JN.

Cell Tissue Bank. 2015 Sep;16(3):351-9. doi: 10.1007/s10561-014-9479-0. Epub 2014 Oct 24.


Regenerative potential of low-concentration SDS-decellularized porcine aortic valved conduits in vivo.

Paniagua Gutierrez JR, Berry H, Korossis S, Mirsadraee S, Lopes SV, da Costa F, Kearney J, Watterson K, Fisher J, Ingham E.

Tissue Eng Part A. 2015 Jan;21(1-2):332-42. doi: 10.1089/ten.TEA.2014.0003. Epub 2014 Oct 1.


Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis.

Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11127-32. doi: 10.1073/pnas.1410432111. Epub 2014 Jul 14.


Biological Effects of Clinically Relevant CoCr Nanoparticles in the Dura Mater: An Organ Culture Study.

Papageorgiou I, Abberton T, Fuller M, Tipper JL, Fisher J, Ingham E.

Nanomaterials (Basel). 2014 Jun 16;4(2):485-504. doi: 10.3390/nano4020485.


Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells.

Mukonoweshuro B, Brown CJ, Fisher J, Ingham E.

J Tissue Eng. 2014 Apr 29;5:2041731414534255. doi: 10.1177/2041731414534255. eCollection 2014.


Development and characterization of acellular porcine pulmonary valve scaffolds for tissue engineering.

Luo J, Korossis SA, Wilshaw SP, Jennings LM, Fisher J, Ingham E.

Tissue Eng Part A. 2014 Nov;20(21-22):2963-74. doi: 10.1089/ten.TEA.2013.0573. Epub 2014 Jun 12.


Generation of a large volume of clinically relevant nanometre-sized ultra-high-molecular-weight polyethylene wear particles for cell culture studies.

Liu A, Ingham E, Fisher J, Tipper JL.

Proc Inst Mech Eng H. 2014 Apr;228(4):418-26. doi: 10.1177/0954411914528308. Epub 2014 Mar 21.

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