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Items: 6


The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells.

Ingenhag D, Reister S, Auer F, Bhatia S, Wildenhain S, Picard D, Remke M, Hoell JI, Kloetgen A, Sohn D, Jänicke RU, Koegler G, Borkhardt A, Hauer J.

Haematologica. 2019 Jan;104(1):35-46. doi: 10.3324/haematol.2018.189407. Epub 2018 Aug 9.


Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells.

Auer F, Ingenhag D, Pinkert S, Kracker S, Hacein-Bey-Abina S, Cavazzana M, Gombert M, Martin-Lorenzo A, Lin MH, Vicente-Dueñas C, Sánchez-García I, Borkhardt A, Hauer J.

Oncotarget. 2017 Sep 7;8(44):75797-75807. doi: 10.18632/oncotarget.20563. eCollection 2017 Sep 29.


GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.

Auer F, Ingenhag D, Bhatia S, Enczmann J, Cobaleda C, Sanchez-Garcia I, Borkhardt A, Hauer J.

Eur J Med Genet. 2016 Mar;59(3):166-72. doi: 10.1016/j.ejmg.2015.11.009. Epub 2015 Nov 26. Review.


Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy.

Vicente-Dueñas C, Hauer J, Ruiz-Roca L, Ingenhag D, Rodríguez-Meira A, Auer F, Borkhardt A, Sánchez-García I.

Semin Cancer Biol. 2015 Jun;32:3-9. doi: 10.1016/j.semcancer.2014.02.001. Epub 2014 Feb 12. Review.


Homeobox protein HB9 binds to the prostaglandin E receptor 2 promoter and inhibits intracellular cAMP mobilization in leukemic cells.

Wildenhain S, Ingenhag D, Ruckert C, Degistirici Ö, Dugas M, Meisel R, Hauer J, Borkhardt A.

J Biol Chem. 2012 Nov 23;287(48):40703-12. doi: 10.1074/jbc.M111.308965. Epub 2012 Oct 8.


Comprehensive array CGH of normal karyotype myelodysplastic syndromes reveals hidden recurrent and individual genomic copy number alterations with prognostic relevance.

Thiel A, Beier M, Ingenhag D, Servan K, Hein M, Moeller V, Betz B, Hildebrandt B, Evers C, Germing U, Royer-Pokora B.

Leukemia. 2011 Mar;25(3):387-99. doi: 10.1038/leu.2010.293. Epub 2011 Jan 28.


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