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Items: 37


EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.

Roos A, Dhruv HD, Peng S, Inge LJ, Tuncali S, Pineda M, Millard N, Mayo Z, Eschbacher JM, Loftus JC, Winkles JA, Tran NL.

Mol Cancer Res. 2018 Jul;16(7):1185-1195. doi: 10.1158/1541-7786.MCR-18-0125. Epub 2018 May 3.


The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.

Hofving T, Arvidsson Y, Almobarak B, Inge L, Pfragner R, Persson M, Stenman G, Kristiansson E, Johanson V, Nilsson O.

Endocr Relat Cancer. 2018 Apr;25(4):X1-X2. doi: 10.1530/ERC-17-0445e. No abstract available.


The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.

Hofving T, Arvidsson Y, Almobarak B, Inge L, Pfragner R, Persson M, Stenman G, Kristiansson E, Johanson V, Nilsson O.

Endocr Relat Cancer. 2018 Mar;25(3):367-380. doi: 10.1530/ERC-17-0445. Erratum in: Endocr Relat Cancer. 2018 Apr;25(4):X1-X2.


LKB1 inactivation occurs in a subset of esophageal adenocarcinomas and is sufficient to drive tumor cell proliferation.

Whitsett TG, Mittal SK, Eschbacher JM, Carson VM, Smith MA, Bremner RM, Inge LJ.

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1891-1899. doi: 10.1016/j.jtcvs.2017.11.067. Epub 2017 Dec 23.


WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer.

Richer AL, Cala JM, O'Brien K, Carson VM, Inge LJ, Whitsett TG.

Cancer Res. 2017 Sep 1;77(17):4663-4672. doi: 10.1158/0008-5472.CAN-16-3565. Epub 2017 Jun 26.


Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy.

Leal-Campanario R, Alarcon-Martinez L, Rieiro H, Martinez-Conde S, Alarcon-Martinez T, Zhao X, LaMee J, Popp PJ, Calhoun ME, Arribas JI, Schlegel AA, Stasi LL, Rho JM, Inge L, Otero-Millan J, Treiman DM, Macknik SL.

Sci Rep. 2017 Feb 27;7:43276. doi: 10.1038/srep43276.


Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.

Roos A, Dhruv HD, Mathews IT, Inge LJ, Tuncali S, Hartman LK, Chow D, Millard N, Yin HH, Kloss J, Loftus JC, Winkles JA, Berens ME, Tran NL.

Oncotarget. 2017 Feb 14;8(7):12234-12246. doi: 10.18632/oncotarget.14685.


Carcinoma cells induce lumen filling and EMT in epithelial cells through soluble E-cadherin-mediated activation of EGFR.

Patil PU, D'Ambrosio J, Inge LJ, Mason RW, Rajasekaran AK.

J Cell Sci. 2015 Dec 1;128(23):4366-79. doi: 10.1242/jcs.173518. Epub 2015 Oct 19.


Genomic profiling toward precision medicine in non-small cell lung cancer: getting beyond EGFR.

Richer AL, Friel JM, Carson VM, Inge LJ, Whitsett TG.

Pharmgenomics Pers Med. 2015 Feb 20;8:63-79. doi: 10.2147/PGPM.S52845. eCollection 2015. Review.


A high-fat diet is associated with altered adipokine production and a more aggressive esophageal adenocarcinoma phenotype in vivo.

Fowler AJ, Richer AL, Bremner RM, Inge LJ.

J Thorac Cardiovasc Surg. 2015 Apr;149(4):1185-91. doi: 10.1016/j.jtcvs.2014.11.076. Epub 2014 Dec 3.


An immunofluorescent method for characterization of Barrett's esophagus cells.

Inge LJ, Fowler AJ, Bremner RM.

J Vis Exp. 2014 Jul 20;(89). doi: 10.3791/51741.


LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress.

Inge LJ, Friel JM, Richer AL, Fowler AJ, Whitsett T, Smith MA, Tran NL, Bremner RM.

Cancer Lett. 2014 Oct 1;352(2):187-95. doi: 10.1016/j.canlet.2014.06.011. Epub 2014 Jul 8.


FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion.

Whitsett TG, Fortin Ensign SP, Dhruv HD, Inge LJ, Kurywchak P, Wolf KK, LoBello J, Kingsley CB, Allen JW, Weiss GJ, Tran NL.

Clin Exp Metastasis. 2014 Aug;31(6):613-23. doi: 10.1007/s10585-014-9653-6. Epub 2014 Apr 8.


Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma.

David JM, Owens TA, Inge LJ, Bremner RM, Rajasekaran AK.

Mol Cancer Ther. 2014 Apr;13(4):788-99. doi: 10.1158/1535-7163.MCT-13-0891. Epub 2014 Feb 3.


The use of quantitative proteomics towards biomarker discovery in lung squamous cell carcinoma.

Whitsett TG, Inge LJ, Tran NL.

Transl Lung Cancer Res. 2013 Dec;2(6):457-60. doi: 10.3978/j.issn.2218-6751.2013.10.17.


Molecular determinants of lung cancer metastasis to the central nervous system.

Whitsett TG, Inge LJ, Dhruv HD, Cheung PY, Weiss GJ, Bremner RM, Winkles JA, Tran NL.

Transl Lung Cancer Res. 2013 Aug;2(4):273-83. doi: 10.3978/j.issn.2218-6751.2013.03.12. Review.


Medication errors in HIV-infected hospitalized patients: a pharmacist's impact.

Eginger KH, Yarborough LL, Inge LD, Basile SA, Floresca D, Aaronson PM.

Ann Pharmacother. 2013 Jul-Aug;47(7-8):953-60. doi: 10.1345/aph.1R773. Epub 2013 Jun 4.


Dasatinib, a small molecule inhibitor of the Src kinase, reduces the growth and activates apoptosis in pre-neoplastic Barrett's esophagus cell lines: evidence for a noninvasive treatment of high-grade dysplasia.

Inge LJ, Fowler AJ, Paquette KM, Richer AL, Tran N, Bremner RM.

J Thorac Cardiovasc Surg. 2013 Feb;145(2):531-8. doi: 10.1016/j.jtcvs.2012.10.041. Epub 2012 Nov 9.


Na,K-ATPase β-subunit cis homo-oligomerization is necessary for epithelial lumen formation in mammalian cells.

Barwe SP, Skay A, McSpadden R, Huynh TP, Langhans SA, Inge LJ, Rajasekaran AK.

J Cell Sci. 2012 Dec 1;125(Pt 23):5711-20. doi: 10.1242/jcs.108795. Epub 2012 Oct 17.


A review of abuse-deterrent opioids for chronic nonmalignant pain.

Moorman-Li R, Motycka CA, Inge LD, Congdon JM, Hobson S, Pokropski B.

P T. 2012 Jul;37(7):412-8.


Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion.

Whitsett TG, Cheng E, Inge L, Asrani K, Jameson NM, Hostetter G, Weiss GJ, Kingsley CB, Loftus JC, Bremner R, Tran NL, Winkles JA.

Am J Pathol. 2012 Jul;181(1):111-20. doi: 10.1016/j.ajpath.2012.03.026. Epub 2012 May 23. Erratum in: Am J Pathol. 2012 Nov;181(5):1889.


Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor.

Inge LJ, Barwe SP, D'Ambrosio J, Gopal J, Lu K, Ryazantsev S, Rajasekaran SA, Rajasekaran AK.

Exp Cell Res. 2011 Apr 1;317(6):838-48. doi: 10.1016/j.yexcr.2010.12.025. Epub 2011 Jan 4.


Immunosuppression-induced bronchial epithelial-mesenchymal transition: a potential contributor to obliterative bronchiolitis.

Felton VM, Inge LJ, Willis BC, Bremner RM, Smith MA.

J Thorac Cardiovasc Surg. 2011 Feb;141(2):523-30. doi: 10.1016/j.jtcvs.2010.10.006. Epub 2010 Dec 15.


Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells.

Gan Y, Shi C, Inge L, Hibner M, Balducci J, Huang Y.

Oncogene. 2010 Sep 2;29(35):4947-58. doi: 10.1038/onc.2010.240. Epub 2010 Jun 21.


Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis.

Rajasekaran SA, Huynh TP, Wolle DG, Espineda CE, Inge LJ, Skay A, Lassman C, Nicholas SB, Harper JF, Reeves AE, Ahmed MM, Leatherman JM, Mullin JM, Rajasekaran AK.

Mol Cancer Ther. 2010 Jun;9(6):1515-24. doi: 10.1158/1535-7163.MCT-09-0832. Epub 2010 May 25.


Genomic characterization of the inflammatory response initiated by surgical intervention and the effect of perioperative cyclooxygenase 2 blockade.

Coon KD, Inge LJ, Swetel K, Felton V, Stafford P, Bremner RM.

J Thorac Cardiovasc Surg. 2010 May;139(5):1253-60, 1260.e1-2. doi: 10.1016/j.jtcvs.2010.01.022.


Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

Barwe SP, Jordan MC, Skay A, Inge L, Rajasekaran SA, Wolle D, Johnson CL, Neco P, Fang K, Rozengurt N, Goldhaber JI, Roos KP, Rajasekaran AK.

J Mol Cell Cardiol. 2009 Oct;47(4):552-60. doi: 10.1016/j.yjmcc.2009.07.018. Epub 2009 Aug 15.


Expression of LKB1 tumor suppressor in non-small cell lung cancer determines sensitivity to 2-deoxyglucose.

Inge LJ, Coon KD, Smith MA, Bremner RM.

J Thorac Cardiovasc Surg. 2009 Mar;137(3):580-6. doi: 10.1016/j.jtcvs.2008.11.029.


Update on the treatment of tuberculosis.

Inge LD, Wilson JW.

Am Fam Physician. 2008 Aug 15;78(4):457-65.


alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling.

Inge LJ, Rajasekaran SA, Wolle D, Barwe SP, Ryazantsev S, Ewing CM, Isaacs WB, Rajasekaran AK.

Mol Cancer Ther. 2008 Jun;7(6):1386-97. doi: 10.1158/1535-7163.MCT-07-2029.


Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin.

Reckamp KL, Gardner BK, Figlin RA, Elashoff D, Krysan K, Dohadwala M, Mao J, Sharma S, Inge L, Rajasekaran A, Dubinett SM.

J Thorac Oncol. 2008 Feb;3(2):117-24. doi: 10.1097/JTO.0b013e3181622bef.


Evidence for a potential tumor suppressor role for the Na,K-ATPase beta1-subunit.

Inge LJ, Rajasekaran SA, Yoshimoto K, Mischel PS, McBride W, Landaw E, Rajasekaran AK.

Histol Histopathol. 2008 Apr;23(4):459-67. doi: 10.14670/HH-23.459.


N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy.

Christiansen JJ, Rajasekaran SA, Inge L, Cheng L, Anilkumar G, Bander NH, Rajasekaran AK.

Mol Cancer Ther. 2005 May;4(5):704-14.


beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.

Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, Garrett E, Wiesmann M, Garcia PD, Fuller JH, Chan V, Randazzo F, Gundel R, Warren RS, Escobedo J, Aukerman SL, Taylor RN, Fantl WJ.

Cancer Res. 2003 Jun 15;63(12):3145-53.


Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo.

Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS.

Cancer Res. 2003 Jun 1;63(11):2742-6.


High-throughput generation and engineering of recombinant human antibodies.

Krebs B, Rauchenberger R, Reiffert S, Rothe C, Tesar M, Thomassen E, Cao M, Dreier T, Fischer D, Höss A, Inge L, Knappik A, Marget M, Pack P, Meng XQ, Schier R, Söhlemann P, Winter J, Wölle J, Kretzschmar T.

J Immunol Methods. 2001 Aug 1;254(1-2):67-84.


Neurons derived from a human teratocarcinoma cell line establish molecular and structural polarity following transplantation into the rodent brain.

Trojanowski JQ, Mantione JR, Lee JH, Seid DP, You T, Inge LJ, Lee VM.

Exp Neurol. 1993 Aug;122(2):283-94.


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