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Items: 48


Sexually Transmitted Infections in Pregnancy and Reproductive Health: Proceedings of the STAR Sexually Transmitted Infection Clinical Trial Group Programmatic Meeting.

Wynn A, Bristow CC, Cristillo AD, Murphy SM, van den Broek N, Muzny C, Kallapur S, Cohen C, Ingalls RR, Wiesenfeld H, Litch JA, Morris SR, Klausner JD.

Sex Transm Dis. 2020 Jan;47(1):5-11. doi: 10.1097/OLQ.0000000000001075.


Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody.

Gulati S, Beurskens FJ, de Kreuk BJ, Roza M, Zheng B, DeOliveira RB, Shaughnessy J, Nowak NA, Taylor RP, Botto M, He X, Ingalls RR, Woodruff TM, Song WC, Schuurman J, Rice PA, Ram S.

PLoS Biol. 2019 Jun 19;17(6):e3000323. doi: 10.1371/journal.pbio.3000323. eCollection 2019 Jun.


Fournier's gangrene as an initial manifestation of acute promyelocytic leukemia: A case report and review of the literature.

Mostaghim A, Dhanani M, Ingalls RR.

SAGE Open Med Case Rep. 2019 Mar 1;7:2050313X19834425. doi: 10.1177/2050313X19834425. eCollection 2019.


Species-specific differences in regulation of macrophage inflammation by the C3a-C3a receptor axis.

Ray TD, Mekasha S, Liang Y, Lu B, Ram S, Ingalls RR.

Innate Immun. 2018 Jan;24(1):66-78. doi: 10.1177/1753425917747044. Epub 2018 Jan 3.


Distinct roles for dietary lipids and Porphyromonas gingivalis infection on atherosclerosis progression and the gut microbiota.

Kramer CD, Simas AM, He X, Ingalls RR, Weinberg EO, Genco CA.

Anaerobe. 2017 Jun;45:19-30. doi: 10.1016/j.anaerobe.2017.04.011. Epub 2017 Apr 23.


Killing of diverse eye pathogens (Acanthamoeba spp., Fusarium solani, and Chlamydia trachomatis) with alcohols.

Aqeel Y, Rodriguez R, Chatterjee A, Ingalls RR, Samuelson J.

PLoS Negl Trop Dis. 2017 Feb 9;11(2):e0005382. doi: 10.1371/journal.pntd.0005382. eCollection 2017 Feb.


Differential expression of toll-like receptors in the human placenta across early gestation.

Pudney J, He X, Masheeb Z, Kindelberger DW, Kuohung W, Ingalls RR.

Placenta. 2016 Oct;46:1-10. doi: 10.1016/j.placenta.2016.07.005. Epub 2016 Jul 26.


Signaling events in pathogen-induced macrophage foam cell formation.

Shaik-Dasthagirisaheb YB, Mekasha S, He X, Gibson FC 3rd, Ingalls RR.

Pathog Dis. 2016 Aug;74(6). pii: ftw074. doi: 10.1093/femspd/ftw074. Epub 2016 Jul 31.


Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans.

Beaulieu LM, Clancy L, Tanriverdi K, Benjamin EJ, Kramer CD, Weinberg EO, He X, Mekasha S, Mick E, Ingalls RR, Genco CA, Freedman JE.

PLoS One. 2015 Jul 6;10(7):e0131688. doi: 10.1371/journal.pone.0131688. eCollection 2015.


Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet.

Kramer CD, Weinberg EO, Gower AC, He X, Mekasha S, Slocum C, Beaulieu LM, Wetzler L, Alekseyev Y, Gibson FC 3rd, Freedman JE, Ingalls RR, Genco CA.

BMC Genomics. 2014 Dec 24;15:1176. doi: 10.1186/1471-2164-15-1176.


The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism.

He X, Berland R, Mekasha S, Christensen TG, Alroy J, Kramnik I, Ingalls RR.

PLoS Pathog. 2013;9(8):e1003569. doi: 10.1371/journal.ppat.1003569. Epub 2013 Aug 29.


Activation of NOD receptors by Neisseria gonorrhoeae modulates the innate immune response.

Mavrogiorgos N, Mekasha S, Yang Y, Kelliher MA, Ingalls RR.

Innate Immun. 2014 May;20(4):377-89. doi: 10.1177/1753425913493453. Epub 2013 Jul 24.


Plasmid-cured Chlamydia caviae activates TLR2-dependent signaling and retains virulence in the guinea pig model of genital tract infection.

Frazer LC, Darville T, Chandra-Kuntal K, Andrews CW Jr, Zurenski M, Mintus M, AbdelRahman YM, Belland RJ, Ingalls RR, O'Connell CM.

PLoS One. 2012;7(1):e30747. doi: 10.1371/journal.pone.0030747. Epub 2012 Jan 24.


CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi.

Hawley KL, Olson CM Jr, Iglesias-Pedraz JM, Navasa N, Cervantes JL, Caimano MJ, Izadi H, Ingalls RR, Pal U, Salazar JC, Radolf JD, Anguita J.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1228-32. doi: 10.1073/pnas.1112078109. Epub 2012 Jan 9.


Protective role of Toll-like receptor 4 in experimental gonococcal infection of female mice.

Packiam M, Wu H, Veit SJ, Mavrogiorgos N, Jerse AE, Ingalls RR.

Mucosal Immunol. 2012 Jan;5(1):19-29. doi: 10.1038/mi.2011.38. Epub 2011 Sep 21.


Enhanced virulence of Chlamydia muridarum respiratory infections in the absence of TLR2 activation.

He X, Nair A, Mekasha S, Alroy J, O'Connell CM, Ingalls RR.

PLoS One. 2011;6(6):e20846. doi: 10.1371/journal.pone.0020846. Epub 2011 Jun 14.


Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.

He X, Mekasha S, Mavrogiorgos N, Fitzgerald KA, Lien E, Ingalls RR.

J Immunol. 2010 May 15;184(10):5743-54. doi: 10.4049/jimmunol.0903937. Epub 2010 Apr 14.


Fibroblast growth factor-inducible 14 (Fn14) is expressed in the lower genital tract and may play a role in amplifying inflammation during infection.

Han ES, Mekasha S, Ingalls RR.

J Reprod Immunol. 2010 Jan;84(1):16-23. doi: 10.1016/j.jri.2009.09.009. Epub 2009 Dec 5.


Mouse strain-dependent differences in susceptibility to Neisseria gonorrhoeae infection and induction of innate immune responses.

Packiam M, Veit SJ, Anderson DJ, Ingalls RR, Jerse AE.

Infect Immun. 2010 Jan;78(1):433-40. doi: 10.1128/IAI.00711-09. Epub 2009 Nov 9.


Plasmid-deficient Chlamydia muridarum fail to induce immune pathology and protect against oviduct disease.

O'Connell CM, Ingalls RR, Andrews CW Jr, Scurlock AM, Darville T.

J Immunol. 2007 Sep 15;179(6):4027-34.


Localization of TLR2 and MyD88 to Chlamydia trachomatis inclusions. Evidence for signaling by intracellular TLR2 during infection with an obligate intracellular pathogen.

O'Connell CM, Ionova IA, Quayle AJ, Visintin A, Ingalls RR.

J Biol Chem. 2006 Jan 20;281(3):1652-9. Epub 2005 Nov 17.


Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.

Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT.

J Immunol. 2002 Oct 1;169(7):3970-7.


Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling.

Fichorova RN, Cronin AO, Lien E, Anderson DJ, Ingalls RR.

J Immunol. 2002 Mar 1;168(5):2424-32.


Toll-like receptors.

Lien E, Ingalls RR.

Crit Care Med. 2002 Jan;30(1 Supp):S1-S11.


Toll-like receptors.

Lien E, Ingalls RR.

Crit Care Med. 2002 Jan;30(1 Suppl):S1-11. Review.


Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.

Flo TH, Ryan L, Kilaas L, Skjâk-Braek G, Ingalls RR, Sundan A, Golenbock DT, Espevik T.

Infect Immun. 2000 Dec;68(12):6770-6.


Divergent response to LPS and bacteria in CD14-deficient murine macrophages.

Moore KJ, Andersson LP, Ingalls RR, Monks BG, Li R, Arnaout MA, Golenbock DT, Freeman MW.

J Immunol. 2000 Oct 15;165(8):4272-80.


Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.

Lien E, Means TK, Heine H, Yoshimura A, Kusumoto S, Fukase K, Fenton MJ, Oikawa M, Qureshi N, Monks B, Finberg RW, Ingalls RR, Golenbock DT.

J Clin Invest. 2000 Feb;105(4):497-504.


Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

Lien E, Sellati TJ, Yoshimura A, Flo TH, Rawadi G, Finberg RW, Carroll JD, Espevik T, Ingalls RR, Radolf JD, Golenbock DT.

J Biol Chem. 1999 Nov 19;274(47):33419-25.


Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2.

Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D.

J Immunol. 1999 Jul 1;163(1):1-5.


Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.

Ingalls RR, Heine H, Lien E, Yoshimura A, Golenbock D.

Infect Dis Clin North Am. 1999 Jun;13(2):341-53, vii. Review.


Membrane expression of soluble endotoxin-binding proteins permits lipopolysaccharide signaling in Chinese hamster ovary fibroblasts independently of CD14.

Ingalls RR, Monks BG, Golenbock DT.

J Biol Chem. 1999 May 14;274(20):13993-8. Erratum in: J Biol Chem 1999 Jul 23;274(30):21490.


CD11/CD18 and CD14 share a common lipid A signaling pathway.

Ingalls RR, Monks BG, Savedra R Jr, Christ WJ, Delude RL, Medvedev AE, Espevik T, Golenbock DT.

J Immunol. 1998 Nov 15;161(10):5413-20.


The CD11/CD18 integrins: characterization of three novel LPS signaling receptors.

Ingalls RR, Arnaout MA, Delude RL, Flaherty S, Savedra R Jr, Golenbock DT.

Prog Clin Biol Res. 1998;397:107-17. No abstract available.


CD11/CD18 leukocyte integrins: new signaling receptors for bacterial endotoxin.

Flaherty SF, Golenbock DT, Milham FH, Ingalls RR.

J Surg Res. 1997 Nov;73(1):85-9.


Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact.

Wurfel MM, Monks BG, Ingalls RR, Dedrick RL, Delude R, Zhou D, Lamping N, Schumann RR, Thieringer R, Fenton MJ, Wright SD, Golenbock D.

J Exp Med. 1997 Dec 15;186(12):2051-6.


Outside-in signaling by lipopolysaccharide through a tailless integrin.

Ingalls RR, Arnaout MA, Golenbock DT.

J Immunol. 1997 Jul 1;159(1):433-8.


Binding of Cryptococcus neoformans to heterologously expressed human complement receptors.

Levitz SM, Tabuni A, Kozel TR, MacGill RS, Ingalls RR, Golenbock DT.

Infect Immun. 1997 Mar;65(3):931-5.


Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system.

Savedra R Jr, Delude RL, Ingalls RR, Fenton MJ, Golenbock DT.

J Immunol. 1996 Sep 15;157(6):2549-54.


The inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated.

Ingalls RR, Rice PA, Qureshi N, Takayama K, Lin JS, Golenbock DT.

Infect Immun. 1995 Aug;63(8):3125-30.


CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide.

Ingalls RR, Golenbock DT.

J Exp Med. 1995 Apr 1;181(4):1473-9.

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