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Items: 1 to 50 of 192

1.

Dissecting molecular mechanisms of resistance to Notch1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts.

Agnusdei V, Minuzzo S, Pinazza M, Gasparini A, Pezzè L, Amaro AA, Pasqualini L, Del Bianco P, Tognon M, Frasson C, Palumbo P, Ciribilli Y, Pfeffer U, Carella M, Amadori A, Indraccolo S.

Haematologica. 2019 Aug 29. pii: haematol.2019.217687. doi: 10.3324/haematol.2019.217687. [Epub ahead of print]

2.

Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer.

Perilli L, Tessarollo S, Albertoni L, Curtarello M, Pastò A, Brunetti E, Fassan M, Rugge M, Indraccolo S, Amadori A, Bortoluzzi S, Zanovello P.

BMC Cancer. 2019 Aug 20;19(1):821. doi: 10.1186/s12885-019-5982-9.

3.

Overcoming platinum-acquired resistance in ovarian cancer patient-derived xenografts.

Ricci F, Brunelli L, Affatato R, Chilà R, Verza M, Indraccolo S, Falcetta F, Fratelli M, Fruscio R, Pastorelli R, Damia G.

Ther Adv Med Oncol. 2019 Jun 24;11:1758835919839543. doi: 10.1177/1758835919839543. eCollection 2019.

4.

Editorial on "The AvaALL Randomized Clinical Trial".

Bonanno L, Pavan A, Pasello G, Indraccolo S.

J Thorac Dis. 2019 May;11(Suppl 9):S1237-S1240. doi: 10.21037/jtd.2019.02.62. No abstract available.

5.

LKB1 and Tumor Metabolism: The Interplay of Immune and Angiogenic Microenvironment in Lung Cancer.

Bonanno L, Zulato E, Pavan A, Attili I, Pasello G, Conte P, Indraccolo S.

Int J Mol Sci. 2019 Apr 16;20(8). pii: E1874. doi: 10.3390/ijms20081874. Review.

6.

PD-1/PD-L1 immune-checkpoint inhibitors in glioblastoma: A concise review.

Caccese M, Indraccolo S, Zagonel V, Lombardi G.

Crit Rev Oncol Hematol. 2019 Mar;135:128-134. doi: 10.1016/j.critrevonc.2018.12.002. Epub 2019 Feb 1. Review.

PMID:
30819441
7.

Platelet-derived growth factor-D enables liver myofibroblasts to promote tumor lymphangiogenesis in cholangiocarcinoma.

Cadamuro M, Brivio S, Mertens J, Vismara M, Moncsek A, Milani C, Fingas C, Cristina Malerba M, Nardo G, Dall'Olmo L, Milani E, Mariotti V, Stecca T, Massani M, Spirli C, Fiorotto R, Indraccolo S, Strazzabosco M, Fabris L.

J Hepatol. 2019 Apr;70(4):700-709. doi: 10.1016/j.jhep.2018.12.004. Epub 2018 Dec 14.

PMID:
30553841
8.

Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial.

Lombardi G, De Salvo GL, Brandes AA, Eoli M, Rudà R, Faedi M, Lolli I, Pace A, Daniele B, Pasqualetti F, Rizzato S, Bellu L, Pambuku A, Farina M, Magni G, Indraccolo S, Gardiman MP, Soffietti R, Zagonel V.

Lancet Oncol. 2019 Jan;20(1):110-119. doi: 10.1016/S1470-2045(18)30675-2. Epub 2018 Dec 3.

PMID:
30522967
9.

Genetic, Epigenetic, and Immunologic Profiling of MMR-Deficient Relapsed Glioblastoma.

Indraccolo S, Lombardi G, Fassan M, Pasqualini L, Giunco S, Marcato R, Gasparini A, Candiotto C, Nalio S, Fiduccia P, Fanelli GN, Pambuku A, Della Puppa A, D'Avella D, Bonaldi L, Gardiman MP, Bertorelle R, De Rossi A, Zagonel V.

Clin Cancer Res. 2019 Mar 15;25(6):1828-1837. doi: 10.1158/1078-0432.CCR-18-1892. Epub 2018 Dec 4.

PMID:
30514778
10.

LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.

Zulato E, Ciccarese F, Agnusdei V, Pinazza M, Nardo G, Iorio E, Curtarello M, Silic-Benussi M, Rossi E, Venturoli C, Panieri E, Santoro MM, Di Paolo V, Quintieri L, Ciminale V, Indraccolo S.

Biochem Pharmacol. 2018 Oct;156:479-490. doi: 10.1016/j.bcp.2018.09.019. Epub 2018 Sep 15.

PMID:
30222967
11.

Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC.

Moro M, Caiola E, Ganzinelli M, Zulato E, Rulli E, Marabese M, Centonze G, Busico A, Pastorino U, de Braud FG, Vernieri C, Simbolo M, Bria E, Scarpa A, Indraccolo S, Broggini M, Sozzi G, Garassino MC.

J Thorac Oncol. 2018 Nov;13(11):1692-1704. doi: 10.1016/j.jtho.2018.07.102. Epub 2018 Aug 24.

12.

Precision medicine in cholangiocarcinoma.

Pellino A, Loupakis F, Cadamuro M, Dadduzio V, Fassan M, Guido M, Cillo U, Indraccolo S, Fabris L.

Transl Gastroenterol Hepatol. 2018 Jul 12;3:40. doi: 10.21037/tgh.2018.07.02. eCollection 2018. Review.

13.

Selective killing of human T-ALL cells: an integrated approach targeting redox homeostasis and the OMA1/OPA1 axis.

Silic-Benussi M, Scattolin G, Cavallari I, Minuzzo S, Del Bianco P, Francescato S, Basso G, Indraccolo S, D'Agostino DM, Ciminale V.

Cell Death Dis. 2018 Aug 1;9(8):822. doi: 10.1038/s41419-018-0870-9.

14.

Correlations between the proportion of type III female genital mutilations in the series and adverse obstetric outcomes: a short meta-analysis.

Indraccolo U, Indraccolo SR, Greco P, Fedeli P.

J Matern Fetal Neonatal Med. 2018 Sep 10:1-3. doi: 10.1080/14767058.2018.1503246. [Epub ahead of print]

PMID:
30025487
15.

Involvement of NADPH Oxidase 1 in Liver Kinase B1-Mediated Effects on Tumor Angiogenesis and Growth.

Zulato E, Ciccarese F, Nardo G, Pinazza M, Agnusdei V, Silic-Benussi M, Ciminale V, Indraccolo S.

Front Oncol. 2018 Jun 4;8:195. doi: 10.3389/fonc.2018.00195. eCollection 2018.

16.

Histone deacetylase 6 controls Notch3 trafficking and degradation in T-cell acute lymphoblastic leukemia cells.

Pinazza M, Ghisi M, Minuzzo S, Agnusdei V, Fossati G, Ciminale V, Pezzè L, Ciribilli Y, Pilotto G, Venturoli C, Amadori A, Indraccolo S.

Oncogene. 2018 Jul;37(28):3839-3851. doi: 10.1038/s41388-018-0234-z. Epub 2018 Apr 12.

17.

Another Case of De Novo 3q26.33q27.3 Microdeletion and Its Medicolegal Sequel.

Indraccolo U, Indraccolo SR, Fedeli P.

Case Rep Obstet Gynecol. 2018 Feb 7;2018:1909056. doi: 10.1155/2018/1909056. eCollection 2018.

18.

Cesarean section in the absence of labor and risk of respiratory complications in newborns: a case-control study.

Indraccolo U, Pace M, Corona G, Bonito M, Indraccolo SR, Di Iorio R.

J Matern Fetal Neonatal Med. 2019 Apr;32(7):1160-1166. doi: 10.1080/14767058.2017.1401999. Epub 2017 Nov 20.

PMID:
29103350
19.

Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.

Serafin V, Capuzzo G, Milani G, Minuzzo SA, Pinazza M, Bortolozzi R, Bresolin S, Porcù E, Frasson C, Indraccolo S, Basso G, Accordi B.

Blood. 2017 Dec 21;130(25):2750-2761. doi: 10.1182/blood-2017-05-784603. Epub 2017 Nov 3.

20.

Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors.

Gandin V, Ceresa C, Esposito G, Indraccolo S, Porchia M, Tisato F, Santini C, Pellei M, Marzano C.

Sci Rep. 2017 Oct 24;7(1):13936. doi: 10.1038/s41598-017-13698-1.

21.

Therapeutic concentrations of digitoxin inhibit endothelial focal adhesion kinase and angiogenesis induced by different growth factors.

Trenti A, Zulato E, Pasqualini L, Indraccolo S, Bolego C, Trevisi L.

Br J Pharmacol. 2017 Sep;174(18):3094-3106. doi: 10.1111/bph.13944. Epub 2017 Aug 11.

22.

Micronized palmitoylethanolamide/trans-polydatin treatment of endometriosis-related pain: a meta-analysis.

Indraccolo U, Indraccolo SR, Mignini F.

Ann Ist Super Sanita. 2017 Apr-Jun;53(2):125-134. doi: 10.4415/ANN_17_02_08. Review.

23.

Clinical features and treatment outcome of non-small cell lung cancer (NSCLC) patients with uncommon or complex epidermal growth factor receptor (EGFR) mutations.

Frega S, Lorenzi M, Fassan M, Indraccolo S, Calabrese F, Favaretto A, Bonanno L, Polo V, Zago G, Lunardi F, Attili I, Pavan A, Rugge M, Guarneri V, Conte P, Pasello G.

Oncotarget. 2017 May 16;8(20):32626-32638. doi: 10.18632/oncotarget.15945.

24.

ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.

Germano G, Morello G, Aveic S, Pinazza M, Minuzzo S, Frasson C, Persano L, Bonvini P, Viola G, Bresolin S, Tregnago C, Paganin M, Pigazzi M, Indraccolo S, Basso G.

Oncotarget. 2017 Apr 18;8(16):26129-26141. doi: 10.18632/oncotarget.15387.

25.

Risk factors for fatality in amniotic fluid embolism: a systematic review and analysis of a data pool.

Indraccolo U, Battistoni C, Mastrantonio I, Di Iorio R, Greco P, Indraccolo SR.

J Matern Fetal Neonatal Med. 2018 Mar;31(5):661-665. doi: 10.1080/14767058.2017.1293034. Epub 2017 Mar 1.

PMID:
28282766
26.

Serendipitous Signs, Symptoms, Laboratory Parameters, and Instrumental Patterns of Amniotic Fluid Embolism: Lessons from an Analysis of Case Reports.

Indraccolo U, Caddeo M, Greco P, Iorio RD, Indraccolo SR.

J Reprod Med. 2017 Mar-Apr;62(3-4):161-72.

PMID:
30230783
27.

LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab.

Bonanno L, De Paoli A, Zulato E, Esposito G, Calabrese F, Favaretto A, Santo A, Conte AD, Chilosi M, Oniga F, Sozzi G, Moro M, Ciccarese F, Nardo G, Bertorelle R, Candiotto C, De Salvo GL, Amadori A, Conte P, Indraccolo S.

Clin Cancer Res. 2017 Jul 1;23(13):3316-3324. doi: 10.1158/1078-0432.CCR-16-2410. Epub 2017 Jan 24.

28.

Symphysis-fundal height predicts difficult evolution of induced labours.

Indraccolo U, Nardocci L, Di Iorio R, Bonito M, Indraccolo SR.

Acta Biomed. 2017 Jan 16;87(3):266-270.

PMID:
28112692
29.

Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1.

Masgras I, Ciscato F, Brunati AM, Tibaldi E, Indraccolo S, Curtarello M, Chiara F, Cannino G, Papaleo E, Lambrughi M, Guzzo G, Gambalunga A, Pizzi M, Guzzardo V, Rugge M, Vuljan SE, Calabrese F, Bernardi P, Rasola A.

Cell Rep. 2017 Jan 17;18(3):659-672. doi: 10.1016/j.celrep.2016.12.056.

30.

Linking metabolic reprogramming to therapy resistance in cancer.

Morandi A, Indraccolo S.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):1-6. doi: 10.1016/j.bbcan.2016.12.004. Epub 2017 Jan 5. Review.

PMID:
28065746
31.

Resistance to glucose starvation as metabolic trait of platinum-resistant human epithelial ovarian cancer cells.

Pastò A, Pagotto A, Pilotto G, De Paoli A, De Salvo GL, Baldoni A, Nicoletto MO, Ricci F, Damia G, Bellio C, Indraccolo S, Amadori A.

Oncotarget. 2017 Jan 24;8(4):6433-6445. doi: 10.18632/oncotarget.14118.

32.

Uncovering Metabolic Effects of Anti-angiogenic Therapy in Tumors by Induced Metabolic Bioluminescence Imaging.

Indraccolo S, Walenta S, Mueller-Klieser W.

Methods Mol Biol. 2016;1464:175-184.

PMID:
27858366
33.

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC.

Perrone F, Baldassarre G, Indraccolo S, Signoriello S, Chiappetta G, Esposito F, Ferrandina G, Franco R, Mezzanzanica D, Sonego M, Zulato E, Zannoni GF, Canzonieri V, Scambia G, Sorio R, Savarese A, Breda E, Scollo P, Ferro A, Tamberi S, Febbraro A, Natale D, Di Maio M, Califano D, Scognamiglio G, Lorusso D, Canevari S, Losito S, Gallo C, Pignata S.

Oncotarget. 2016 Nov 8;7(45):72654-72661. doi: 10.18632/oncotarget.12056.

34.

In vivo Magnetic Resonance Metabolic and Morphofunctional Fingerprints in Experimental Models of Human Ovarian Cancer.

Canese R, Mezzanzanica D, Bagnoli M, Indraccolo S, Canevari S, Podo F, Iorio E.

Front Oncol. 2016 Jun 28;6:164. doi: 10.3389/fonc.2016.00164. eCollection 2016. Review.

35.

Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma.

Cadamuro M, Spagnuolo G, Sambado L, Indraccolo S, Nardo G, Rosato A, Brivio S, Caslini C, Stecca T, Massani M, Bassi N, Novelli E, Spirli C, Fabris L, Strazzabosco M.

Cancer Res. 2016 Aug 15;76(16):4775-84. doi: 10.1158/0008-5472.CAN-16-0188. Epub 2016 Jun 21.

36.

Vascular endothelial growth factor blockade elicits a stable metabolic shift in tumor cells: therapeutic implications.

Indraccolo S.

Mol Cell Oncol. 2015 Feb 3;3(2):e1008307. doi: 10.1080/23723556.2015.1008307. eCollection 2016 Mar.

37.

Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients.

Jiménez-Valerio G, Martínez-Lozano M, Bassani N, Vidal A, Ochoa-de-Olza M, Suárez C, García-Del-Muro X, Carles J, Viñals F, Graupera M, Indraccolo S, Casanovas O.

Cell Rep. 2016 May 10;15(6):1134-43. doi: 10.1016/j.celrep.2016.04.015. Epub 2016 Apr 28.

38.

Morphological and genetic heterogeneity in multifocal lung adenocarcinoma: The case of a never-smoker woman.

Bonanno L, Calabrese F, Nardo G, Calistri D, Tebaldi M, Tedaldi G, Polo V, Vuljan S, Favaretto A, Conte P, Amadori A, Rea F, Indraccolo S.

Lung Cancer. 2016 Jun;96:52-5. doi: 10.1016/j.lungcan.2016.03.009. Epub 2016 Mar 25.

PMID:
27133750
39.

A hypoxic signature marks tumors formed by disseminated tumor cells in the BALB-neuT mammary cancer model.

Msaki A, Pastò A, Curtarello M, Arigoni M, Barutello G, Calogero RA, Macagno M, Cavallo F, Amadori A, Indraccolo S.

Oncotarget. 2016 May 31;7(22):33081-95. doi: 10.18632/oncotarget.8859.

40.

Reconstruction of gene regulatory modules from RNA silencing of IFN-α modulators: experimental set-up and inference method.

Grassi A, Di Camillo B, Ciccarese F, Agnusdei V, Zanovello P, Amadori A, Finesso L, Indraccolo S, Toffolo GM.

BMC Genomics. 2016 Mar 12;17:228. doi: 10.1186/s12864-016-2525-5.

41.

Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia.

Jost TR, Borga C, Radaelli E, Romagnani A, Perruzza L, Omodho L, Cazzaniga G, Biondi A, Indraccolo S, Thelen M, Te Kronnie G, Grassi F.

J Leukoc Biol. 2016 Jun;99(6):1077-87. doi: 10.1189/jlb.5MA0915-394R. Epub 2016 Mar 1.

PMID:
26931577
42.

Potential of Induced Metabolic Bioluminescence Imaging to Uncover Metabolic Effects of Antiangiogenic Therapy in Tumors.

Indraccolo S, Mueller-Klieser W.

Front Oncol. 2016 Feb 1;6:15. doi: 10.3389/fonc.2016.00015. eCollection 2016. Review.

43.

An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts.

Pinazza M, Borga C, Agnusdei V, Minuzzo S, Fossati G, Paganin M, Michielotto B, De Paoli A, Basso G, Amadori A, te Kronnie G, Indraccolo S.

Cell Death Dis. 2016 Jan 14;6:e2047. doi: 10.1038/cddis.2015.394.

44.

Calcineurin and GSK-3 inhibition sensitizes T-cell acute lymphoblastic leukemia cells to apoptosis through X-linked inhibitor of apoptosis protein degradation.

Tosello V, Bordin F, Yu J, Agnusdei V, Indraccolo S, Basso G, Amadori A, Piovan E.

Leukemia. 2016 Apr;30(4):812-22. doi: 10.1038/leu.2015.335. Epub 2015 Dec 9.

PMID:
26648536
45.

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.

Zucal C, D'Agostino VG, Casini A, Mantelli B, Thongon N, Soncini D, Caffa I, Cea M, Ballestrero A, Quattrone A, Indraccolo S, Nencioni A, Provenzani A.

BMC Cancer. 2015 Nov 5;15:855. doi: 10.1186/s12885-015-1845-1.

46.

Manipulation of tumor metabolism for therapeutic approaches: ovarian cancer-derived cell lines as a model system.

Goetze K, Fabian CG, Siebers A, Binz L, Faber D, Indraccolo S, Nardo G, Sattler UG, Mueller-Klieser W.

Cell Oncol (Dordr). 2015 Oct;38(5):377-85. doi: 10.1007/s13402-015-0237-5. Epub 2015 Aug 19.

PMID:
26288178
47.

External cephalic version for singleton breech presentation: proposal of a practical check-list for obstetricians.

Indraccolo U, Graziani C, Di Iorio R, Corona G, Bonito M, Indraccolo SR.

Eur Rev Med Pharmacol Sci. 2015 Jul;19(13):2340-53. Review.

48.

Cesarean section on maternal request: should it be formally prohibited in Italy?

Indraccolo U, Scutiero G, Matteo M, Indraccolo SR, Greco P.

Ann Ist Super Sanita. 2015;51(2):162-6. doi: 10.4415/ANN_15_02_15.

49.

Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus.

Giunco S, Celeghin A, Gianesin K, Dolcetti R, Indraccolo S, De Rossi A.

Cell Death Dis. 2015 May 28;6:e1774. doi: 10.1038/cddis.2015.145.

50.

Metformin: a modulator of bevacizumab activity in cancer? A case report.

Indraccolo S, Randon G, Zulato E, Nardin M, Aliberti C, Pomerri F, Casarin A, Nicoletto MO.

Cancer Biol Ther. 2015;16(2):210-4. doi: 10.1080/15384047.2014.1002366.

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