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Items: 1 to 50 of 60

1.

Cardiac remodeling in response to embryonic crude oil exposure involves unconventional NKX family members and innate immunity genes.

Gardner LD, Peck KA, Goetz GW, Linbo TL, Cameron J, Scholz NL, Block BA, Incardona JP.

J Exp Biol. 2019 Oct 9. pii: jeb.205567. doi: 10.1242/jeb.205567. [Epub ahead of print]

PMID:
31597731
2.

Embryonic Crude Oil Exposure Impairs Growth and Lipid Allocation in a Keystone Arctic Forage Fish.

Laurel BJ, Copeman LA, Iseri P, Spencer ML, Hutchinson G, Nordtug T, Donald CE, Meier S, Allan SE, Boyd DT, Ylitalo GM, Cameron JR, French BL, Linbo TL, Scholz NL, Incardona JP.

iScience. 2019 Sep 27;19:1101-1113. doi: 10.1016/j.isci.2019.08.051. Epub 2019 Aug 30.

3.

Polycyclic aromatic hydrocarbons in Pacific herring (Clupea pallasii) embryos exposed to creosote-treated pilings during a piling-removal project in a nearshore marine habitat of Puget Sound.

West JE, Carey AJ, Ylitalo GM, Incardona JP, Edmunds RC, Sloan CA, Niewolny LA, Lanksbury JA, O'Neill SM.

Mar Pollut Bull. 2019 May;142:253-262. doi: 10.1016/j.marpolbul.2019.03.028. Epub 2019 Mar 30.

4.

Crude oil cardiotoxicity to red drum embryos is independent of oil dispersion energy.

Morris JM, Gielazyn M, Krasnec MO, Takeshita R, Forth HP, Labenia JS, Linbo TL, French BL, Gill JA, Baldwin DH, Scholz NL, Incardona JP.

Chemosphere. 2018 Dec;213:205-214. doi: 10.1016/j.chemosphere.2018.09.015. Epub 2018 Sep 6.

PMID:
30223125
5.

Interspecies variation in the susceptibility of adult Pacific salmon to toxic urban stormwater runoff.

McIntyre JK, Lundin JI, Cameron JR, Chow MI, Davis JW, Incardona JP, Scholz NL.

Environ Pollut. 2018 Jul;238:196-203. doi: 10.1016/j.envpol.2018.03.012. Epub 2018 Mar 20.

6.

Molecular Mechanisms of Crude Oil Developmental Toxicity in Fish.

Incardona JP.

Arch Environ Contam Toxicol. 2017 Jul;73(1):19-32. doi: 10.1007/s00244-017-0381-1. Epub 2017 Jul 10.

PMID:
28695261
7.

Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod.

Sørensen L, Sørhus E, Nordtug T, Incardona JP, Linbo TL, Giovanetti L, Karlsen Ø, Meier S.

PLoS One. 2017 Jul 5;12(7):e0180048. doi: 10.1371/journal.pone.0180048. eCollection 2017.

8.

A Novel Cardiotoxic Mechanism for a Pervasive Global Pollutant.

Brette F, Shiels HA, Galli GL, Cros C, Incardona JP, Scholz NL, Block BA.

Sci Rep. 2017 Jan 31;7:41476. doi: 10.1038/srep41476.

9.

Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish.

Sørhus E, Incardona JP, Furmanek T, Goetz GW, Scholz NL, Meier S, Edvardsen RB, Jentoft S.

Elife. 2017 Jan 24;6. pii: e20707. doi: 10.7554/eLife.20707.

10.

Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development.

Sørhus E, Incardona JP, Karlsen Ø, Linbo T, Sørensen L, Nordtug T, van der Meeren T, Thorsen A, Thorbjørnsen M, Jentoft S, Edvardsen RB, Meier S.

Sci Rep. 2016 Aug 10;6:31058. doi: 10.1038/srep31058.

11.

The influence of heart developmental anatomy on cardiotoxicity-based adverse outcome pathways in fish.

Incardona JP, Scholz NL.

Aquat Toxicol. 2016 Aug;177:515-25. doi: 10.1016/j.aquatox.2016.06.016. Epub 2016 Jun 21. Review.

PMID:
27447099
12.

Developmental transcriptomics in Atlantic haddock: Illuminating pattern formation and organogenesis in non-model vertebrates.

Sørhus E, Incardona JP, Furmanek T, Jentoft S, Meier S, Edvardsen RB.

Dev Biol. 2016 Mar 15;411(2):301-313. doi: 10.1016/j.ydbio.2016.02.012. Epub 2016 Feb 12.

13.

Confirmation of Stormwater Bioretention Treatment Effectiveness Using Molecular Indicators of Cardiovascular Toxicity in Developing Fish.

McIntyre JK, Edmunds RC, Redig MG, Mudrock EM, Davis JW, Incardona JP, Stark JD, Scholz NL.

Environ Sci Technol. 2016 Feb 2;50(3):1561-9. doi: 10.1021/acs.est.5b04786. Epub 2016 Jan 19.

PMID:
26727247
14.

Corresponding morphological and molecular indicators of crude oil toxicity to the developing hearts of mahi mahi.

Edmunds RC, Gill JA, Baldwin DH, Linbo TL, French BL, Brown TL, Esbaugh AJ, Mager EM, Stieglitz J, Hoenig R, Benetti D, Grosell M, Scholz NL, Incardona JP.

Sci Rep. 2015 Dec 10;5:17326. doi: 10.1038/srep17326.

15.

Severe Coal Tar Sealcoat Runoff Toxicity to Fish Is Prevented by Bioretention Filtration.

McIntyre JK, Edmunds RC, Anulacion BF, Davis JW, Incardona JP, Stark JD, Scholz NL.

Environ Sci Technol. 2016 Feb 2;50(3):1570-8. doi: 10.1021/acs.est.5b04928. Epub 2016 Jan 15.

PMID:
26654684
16.

The effects of weathering and chemical dispersion on Deepwater Horizon crude oil toxicity to mahi-mahi (Coryphaena hippurus) early life stages.

Esbaugh AJ, Mager EM, Stieglitz JD, Hoenig R, Brown TL, French BL, Linbo TL, Lay C, Forth H, Scholz NL, Incardona JP, Morris JM, Benetti DD, Grosell M.

Sci Total Environ. 2016 Feb 1;543(Pt A):644-651. doi: 10.1016/j.scitotenv.2015.11.068. Epub 2015 Nov 22.

PMID:
26613518
17.

Differential Toxicokinetics Determines the Sensitivity of Two Marine Embryonic Fish Exposed to Iranian Heavy Crude Oil.

Jung JH, Kim M, Yim UH, Ha SY, Shim WJ, Chae YS, Kim H, Incardona JP, Linbo TL, Kwon JH.

Environ Sci Technol. 2015 Nov 17;49(22):13639-48. doi: 10.1021/acs.est.5b03729. Epub 2015 Nov 9.

PMID:
26458192
18.

Very low embryonic crude oil exposures cause lasting cardiac defects in salmon and herring.

Incardona JP, Carls MG, Holland L, Linbo TL, Baldwin DH, Myers MS, Peck KA, Tagal M, Rice SD, Scholz NL.

Sci Rep. 2015 Sep 8;5:13499. doi: 10.1038/srep13499.

19.

Exposure to Deepwater Horizon weathered crude oil increases routine metabolic demand in chub mackerel, Scomber japonicus.

Klinger DH, Dale JJ, Machado BE, Incardona JP, Farwell CJ, Block BA.

Mar Pollut Bull. 2015 Sep 15;98(1-2):259-66. doi: 10.1016/j.marpolbul.2015.06.039. Epub 2015 Jul 22.

PMID:
26210587
20.

In response: scaling polycyclic aromatic hydrocarbon toxicity to fish early life stages: a governmental perspective.

Scholz NL, Incardona JP.

Environ Toxicol Chem. 2015 Mar;34(3):459-61. doi: 10.1002/etc.2830. No abstract available.

PMID:
25711441
21.

Zebrafish and clean water technology: assessing soil bioretention as a protective treatment for toxic urban runoff.

McIntyre JK, Davis JW, Incardona JP, Stark JD, Anulacion BF, Scholz NL.

Sci Total Environ. 2014 Dec 1;500-501:173-80. doi: 10.1016/j.scitotenv.2014.08.066. Epub 2014 Sep 15.

22.

An evaluation of background levels and sources of polycyclic aromatic hydrocarbons in naturally spawned embryos of Pacific herring (Clupea pallasii) from Puget Sound, Washington, USA.

West JE, O'Neill SM, Ylitalo GM, Incardona JP, Doty DC, Dutch ME.

Sci Total Environ. 2014 Nov 15;499:114-24. doi: 10.1016/j.scitotenv.2014.08.042. Epub 2014 Sep 1.

PMID:
25181043
23.

Toward enhanced MIQE compliance: reference residual normalization of qPCR gene expression data.

Edmunds RC, McIntyre JK, Luckenbach JA, Baldwin DH, Incardona JP.

J Biomol Tech. 2014 Jul;25(2):54-60. doi: 10.7171/jbt.14-2502-003.

24.

Acute embryonic or juvenile exposure to Deepwater Horizon crude oil impairs the swimming performance of mahi-mahi (Coryphaena hippurus).

Mager EM, Esbaugh AJ, Stieglitz JD, Hoenig R, Bodinier C, Incardona JP, Scholz NL, Benetti DD, Grosell M.

Environ Sci Technol. 2014 Jun 17;48(12):7053-61. doi: 10.1021/es501628k. Epub 2014 Jun 9.

PMID:
24857158
25.

Deepwater Horizon crude oil impacts the developing hearts of large predatory pelagic fish.

Incardona JP, Gardner LD, Linbo TL, Brown TL, Esbaugh AJ, Mager EM, Stieglitz JD, French BL, Labenia JS, Laetz CA, Tagal M, Sloan CA, Elizur A, Benetti DD, Grosell M, Block BA, Scholz NL.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1510-8. doi: 10.1073/pnas.1320950111. Epub 2014 Mar 24.

26.

Crude oil impairs cardiac excitation-contraction coupling in fish.

Brette F, Machado B, Cros C, Incardona JP, Scholz NL, Block BA.

Science. 2014 Feb 14;343(6172):772-6. doi: 10.1126/science.1242747.

PMID:
24531969
27.

Exxon Valdez to Deepwater Horizon: comparable toxicity of both crude oils to fish early life stages.

Incardona JP, Swarts TL, Edmunds RC, Linbo TL, Aquilina-Beck A, Sloan CA, Gardner LD, Block BA, Scholz NL.

Aquat Toxicol. 2013 Oct 15;142-143:303-16. doi: 10.1016/j.aquatox.2013.08.011. Epub 2013 Aug 31.

PMID:
24080042
28.

Geologically distinct crude oils cause a common cardiotoxicity syndrome in developing zebrafish.

Jung JH, Hicken CE, Boyd D, Anulacion BF, Carls MG, Shim WJ, Incardona JP.

Chemosphere. 2013 May;91(8):1146-55. doi: 10.1016/j.chemosphere.2013.01.019. Epub 2013 Mar 5.

PMID:
23481301
29.

Potent phototoxicity of marine bunker oil to translucent herring embryos after prolonged weathering.

Incardona JP, Vines CA, Linbo TL, Myers MS, Sloan CA, Anulacion BF, Boyd D, Collier TK, Morgan S, Cherr GN, Scholz NL.

PLoS One. 2012;7(2):e30116. doi: 10.1371/journal.pone.0030116. Epub 2012 Feb 1.

30.

Unexpectedly high mortality in Pacific herring embryos exposed to the 2007 Cosco Busan oil spill in San Francisco Bay.

Incardona JP, Vines CA, Anulacion BF, Baldwin DH, Day HL, French BL, Labenia JS, Linbo TL, Myers MS, Olson OP, Sloan CA, Sol S, Griffin FJ, Menard K, Morgan SG, West JE, Collier TK, Ylitalo GM, Cherr GN, Scholz NL.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):E51-8. doi: 10.1073/pnas.1108884109. Epub 2011 Dec 27.

31.

Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development.

Incardona JP, Linbo TL, Scholz NL.

Toxicol Appl Pharmacol. 2011 Dec 1;257(2):242-9. doi: 10.1016/j.taap.2011.09.010. Epub 2011 Sep 19.

PMID:
21964300
32.

Sublethal exposure to crude oil during embryonic development alters cardiac morphology and reduces aerobic capacity in adult fish.

Hicken CE, Linbo TL, Baldwin DH, Willis ML, Myers MS, Holland L, Larsen M, Stekoll MS, Rice SD, Collier TK, Scholz NL, Incardona JP.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7086-90. doi: 10.1073/pnas.1019031108. Epub 2011 Apr 11.

33.

Oil spills and fish health: exposing the heart of the matter.

Incardona JP, Collier TK, Scholz NL.

J Expo Sci Environ Epidemiol. 2011 Jan-Feb;21(1):3-4. doi: 10.1038/jes.2010.51. Epub 2010 Nov 10.

PMID:
21068721
34.

AhR2-mediated, CYP1A-independent cardiovascular toxicity in zebrafish (Danio rerio) embryos exposed to retene.

Scott JA, Incardona JP, Pelkki K, Shepardson S, Hodson PV.

Aquat Toxicol. 2011 Jan 17;101(1):165-74. doi: 10.1016/j.aquatox.2010.09.016. Epub 2010 Oct 30.

PMID:
21040984
35.

In vitro electrocardiographic and cardiac ion channel effects of (-)-epigallocatechin-3-gallate, the main catechin of green tea.

Kang J, Cheng H, Ji J, Incardona J, Rampe D.

J Pharmacol Exp Ther. 2010 Aug;334(2):619-26. doi: 10.1124/jpet.110.169391. Epub 2010 May 18.

PMID:
20484151
36.

Natural sunlight and residual fuel oils are an acutely lethal combination for fish embryos.

Hatlen K, Sloan CA, Burrows DG, Collier TK, Scholz NL, Incardona JP.

Aquat Toxicol. 2010 Aug 1;99(1):56-64. doi: 10.1016/j.aquatox.2010.04.002. Epub 2010 Apr 10.

PMID:
20435358
37.

Models of torsades de pointes: effects of FPL64176, DPI201106, dofetilide, and chromanol 293B in isolated rabbit and guinea pig hearts.

Cheng HC, Incardona J.

J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):174-84. doi: 10.1016/j.vascn.2009.05.010. Epub 2009 Jun 11.

PMID:
19524054
38.

Cardiac arrhythmia is the primary response of embryonic Pacific herring (Clupea pallasi) exposed to crude oil during weathering.

Incardona JP, Carls MG, Day HL, Sloan CA, Bolton JL, Collier TK, Scholz NL.

Environ Sci Technol. 2009 Jan 1;43(1):201-7.

PMID:
19209607
39.

Fish embryos are damaged by dissolved PAHs, not oil particles.

Carls MG, Holland L, Larsen M, Collier TK, Scholz NL, Incardona JP.

Aquat Toxicol. 2008 Jun 23;88(2):121-7. doi: 10.1016/j.aquatox.2008.03.014. Epub 2008 Apr 7.

PMID:
18479765
40.

Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47).

Lema SC, Schultz IR, Scholz NL, Incardona JP, Swanson P.

Aquat Toxicol. 2007 May 31;82(4):296-307. Epub 2007 Mar 7.

PMID:
17412433
41.

Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism.

Incardona JP, Day HL, Collier TK, Scholz NL.

Toxicol Appl Pharmacol. 2006 Dec 15;217(3):308-21. Epub 2006 Oct 7.

PMID:
17112560
42.

Epithelial trafficking of Sonic hedgehog by megalin.

Morales CR, Zeng J, El Alfy M, Barth JL, Chintalapudi MR, McCarthy RA, Incardona JP, Argraves WS.

J Histochem Cytochem. 2006 Oct;54(10):1115-27. Epub 2006 Jun 26.

43.

The developmental neurotoxicity of fipronil: notochord degeneration and locomotor defects in zebrafish embryos and larvae.

Stehr CM, Linbo TL, Incardona JP, Scholz NL.

Toxicol Sci. 2006 Jul;92(1):270-8. Epub 2006 Apr 12.

PMID:
16611622
44.

Dissolved copper triggers cell death in the peripheral mechanosensory system of larval fish.

Linbo TL, Stehr CM, Incardona JP, Scholz NL.

Environ Toxicol Chem. 2006 Feb;25(2):597-603.

PMID:
16519324
45.

Isolated perfused and paced guinea pig heart to test for drug-induced changes of the QT interval.

Cheng HC, Incardona J, McCullough B.

J Pharmacol Toxicol Methods. 2006 Nov-Dec;54(3):278-87. Epub 2006 Feb 28.

PMID:
16507347
46.

Aryl hydrocarbon receptor-independent toxicity of weathered crude oil during fish development.

Incardona JP, Carls MG, Teraoka H, Sloan CA, Collier TK, Scholz NL.

Environ Health Perspect. 2005 Dec;113(12):1755-62.

47.
48.

Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel.

Kang J, Chen XL, Wang H, Ji J, Cheng H, Incardona J, Reynolds W, Viviani F, Tabart M, Rampe D.

Mol Pharmacol. 2005 Mar;67(3):827-36. Epub 2004 Nov 17.

PMID:
15548764
49.

Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons.

Incardona JP, Collier TK, Scholz NL.

Toxicol Appl Pharmacol. 2004 Apr 15;196(2):191-205.

PMID:
15081266
50.

Sonic hedgehog induces the segregation of patched and smoothened in endosomes.

Incardona JP, Gruenberg J, Roelink H.

Curr Biol. 2002 Jun 25;12(12):983-95.

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