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Items: 1 to 50 of 462

1.

Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.

Tanikawa C, Kamatani Y, Toyoshima O, Sakamoto H, Ito H, Takahashi A, Momozawa Y, Hirata M, Fuse N, Takai-Igarashi T, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Hishida A, Wakai K, Furusyo N, Murakami Y, Nakamura Y, Imoto I, Inazawa J, Oze I, Sato N, Tanioka F, Sugimura H, Hirose H, Yoshida T, Matsuo K, Kubo M, Matsuda K.

Cancer Sci. 2018 Oct 3. doi: 10.1111/cas.13815. [Epub ahead of print]

2.

Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line.

Sato T, Muramatsu T, Tanabe M, Inazawa J.

Cancer Sci. 2018 Nov;109(11):3623-3633. doi: 10.1111/cas.13783. Epub 2018 Sep 21.

3.

Publisher Correction: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein.

Tonouchi E, Gen Y, Muramatsu T, Hiramoto H, Tanimoto K, Inoue J, Inazawa J.

Sci Rep. 2018 Apr 25;8(1):6769. doi: 10.1038/s41598-018-24861-7.

4.

Ovarian cancer therapeutic potential of glutamine depletion based on GS expression.

Furusawa A, Miyamoto M, Takano M, Tsuda H, Song YS, Aoki D, Miyasaka N, Inazawa J, Inoue J.

Carcinogenesis. 2018 May 28;39(6):758-766. doi: 10.1093/carcin/bgy033.

PMID:
29617730
5.

miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein.

Tonouchi E, Gen Y, Muramatsu T, Hiramoto H, Tanimoto K, Inoue J, Inazawa J.

Sci Rep. 2018 Mar 14;8(1):4482. doi: 10.1038/s41598-018-22767-y. Erratum in: Sci Rep. 2018 Apr 25;8(1):6769.

6.

GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y, Nakamura Y, Kubo M, Matsuda K.

Carcinogenesis. 2018 May 3;39(5):652-660. doi: 10.1093/carcin/bgy026.

PMID:
29471430
7.

Mild prominence of the Sylvian fissure in a Bainbridge-Ropers syndrome patient with a novel frameshift variant in ASXL3.

Chinen Y, Nakamura S, Ganaha A, Hayashi S, Inazawa J, Yanagi K, Nakanishi K, Kaname T, Naritomi K.

Clin Case Rep. 2017 Dec 28;6(2):330-336. doi: 10.1002/ccr3.1361. eCollection 2018 Feb.

8.

The Japanese Society of Pathology Guidelines on the handling of pathological tissue samples for genomic research: Standard operating procedures based on empirical analyses.

Kanai Y, Nishihara H, Miyagi Y, Tsuruyama T, Taguchi K, Katoh H, Takeuchi T, Gotoh M, Kuramoto J, Arai E, Ojima H, Shibuya A, Yoshida T, Akahane T, Kasajima R, Morita KI, Inazawa J, Sasaki T, Fukayama M, Oda Y.

Pathol Int. 2018 Feb;68(2):63-90. doi: 10.1111/pin.12631.

PMID:
29431262
9.

Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.

Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe A.

Sci Rep. 2018 Jan 15;8(1):789. doi: 10.1038/s41598-017-19127-7.

10.

Comprehensive investigation of CASK mutations and other genetic etiologies in 41 patients with intellectual disability and microcephaly with pontine and cerebellar hypoplasia (MICPCH).

Hayashi S, Uehara DT, Tanimoto K, Mizuno S, Chinen Y, Fukumura S, Takanashi JI, Osaka H, Okamoto N, Inazawa J.

PLoS One. 2017 Aug 7;12(8):e0181791. doi: 10.1371/journal.pone.0181791. eCollection 2017.

11.

miR-432 Induces NRF2 Stabilization by Directly Targeting KEAP1.

Akdemir B, Nakajima Y, Inazawa J, Inoue J.

Mol Cancer Res. 2017 Nov;15(11):1570-1578. doi: 10.1158/1541-7786.MCR-17-0232. Epub 2017 Jul 31.

12.

miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer.

Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, Inazawa J.

Sci Rep. 2017 Jun 21;7(1):4002. doi: 10.1038/s41598-017-04191-w.

13.

Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma.

Nagata H, Kozaki KI, Muramatsu T, Hiramoto H, Tanimoto K, Fujiwara N, Imoto S, Ichikawa D, Otsuji E, Miyano S, Kawano T, Inazawa J.

Oncotarget. 2017 Jun 6;8(23):37740-37750. doi: 10.18632/oncotarget.17147.

14.

Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection.

Okuda M, Inoue J, Fujiwara N, Kawano T, Inazawa J.

Oncotarget. 2017 May 23;8(21):34670-34677. doi: 10.18632/oncotarget.16668.

15.

Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells.

Takahashi H, Inoue J, Sakaguchi K, Takagi M, Mizutani S, Inazawa J.

Oncogene. 2017 Jul 27;36(30):4267-4276. doi: 10.1038/onc.2017.59. Epub 2017 Mar 27.

16.

Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma.

Sakha S, Muramatsu T, Ueda K, Inazawa J.

Sci Rep. 2016 Dec 8;6:38750. doi: 10.1038/srep38750.

17.

Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma.

Oikawa Y, Morita KI, Kayamori K, Tanimoto K, Sakamoto K, Katoh H, Ishikawa S, Inazawa J, Harada H.

Cancer Sci. 2017 Feb;108(2):256-266. doi: 10.1111/cas.13126.

18.

Association between maternal education and malocclusion in Mongolian adolescents: a cross-sectional study.

Tumurkhuu T, Fujiwara T, Komazaki Y, Kawaguchi Y, Tanaka T, Inazawa J, Ganburged G, Bazar A, Ogawa T, Moriyama K.

BMJ Open. 2016 Nov 1;6(11):e012283. doi: 10.1136/bmjopen-2016-012283.

19.

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.

Shiraishi K, Okada Y, Takahashi A, Kamatani Y, Momozawa Y, Ashikawa K, Kunitoh H, Matsumoto S, Takano A, Shimizu K, Goto A, Tsuta K, Watanabe S, Ohe Y, Watanabe Y, Goto Y, Nokihara H, Furuta K, Yoshida A, Goto K, Hishida T, Tsuboi M, Tsuchihara K, Miyagi Y, Nakayama H, Yokose T, Tanaka K, Nagashima T, Ohtaki Y, Maeda D, Imai K, Minamiya Y, Sakamoto H, Saito A, Shimada Y, Sunami K, Saito M, Inazawa J, Nakamura Y, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T.

Nat Commun. 2016 Aug 9;7:12451. doi: 10.1038/ncomms12451.

20.

Cytogenetic analysis of spontaneously discharged products of conception by array-based comparative genomic hybridization.

Ozawa N, Sago H, Matsuoka K, Maruyama T, Migita O, Aizu Y, Inazawa J.

Springerplus. 2016 Jun 24;5(1):874. doi: 10.1186/s40064-016-2594-6. eCollection 2016.

21.

Down-regulation of LAPTM5 in human cancer cells.

Nuylan M, Kawano T, Inazawa J, Inoue J.

Oncotarget. 2016 May 10;7(19):28320-8. doi: 10.18632/oncotarget.8614.

22.

The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.

Muramatsu T, Kozaki KI, Imoto S, Yamaguchi R, Tsuda H, Kawano T, Fujiwara N, Morishita M, Miyano S, Inazawa J.

Oncogene. 2016 Oct 6;35(40):5304-5316. doi: 10.1038/onc.2016.71. Epub 2016 Apr 4.

PMID:
27041563
23.

Significant impact of miRNA-target gene networks on genetics of human complex traits.

Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E, Iotchkova V, Soranzo N, Inazawa J, Tanaka T.

Sci Rep. 2016 Mar 1;6:22223. doi: 10.1038/srep22223.

24.

Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system.

Morishita M, Muramatsu T, Suto Y, Hirai M, Konishi T, Hayashi S, Shigemizu D, Tsunoda T, Moriyama K, Inazawa J.

Oncotarget. 2016 Mar 1;7(9):10182-92. doi: 10.18632/oncotarget.7186.

25.

Increase in GFAP-positive astrocytes in histone demethylase GASC1/KDM4C/JMJD2C hypomorphic mutant mice.

Sudo G, Kagawa T, Kokubu Y, Inazawa J, Taga T.

Genes Cells. 2016 Mar;21(3):218-25. doi: 10.1111/gtc.12331. Epub 2016 Jan 25.

26.

SNP array screening of cryptic genomic imbalances in 450 Japanese subjects with intellectual disability and multiple congenital anomalies previously negative for large rearrangements.

Uehara DT, Hayashi S, Okamoto N, Mizuno S, Chinen Y, Kosaki R, Kosho T, Kurosawa K, Matsumoto H, Mitsubuchi H, Numabe H, Saitoh S, Makita Y, Hata A, Imoto I, Inazawa J.

J Hum Genet. 2016 Apr;61(4):335-43. doi: 10.1038/jhg.2015.154. Epub 2016 Jan 7.

PMID:
26740234
27.

Simultaneous Detection of Both Single Nucleotide Variations and Copy Number Alterations by Next-Generation Sequencing in Gorlin Syndrome.

Morita K, Naruto T, Tanimoto K, Yasukawa C, Oikawa Y, Masuda K, Imoto I, Inazawa J, Omura K, Harada H.

PLoS One. 2015 Nov 6;10(11):e0140480. doi: 10.1371/journal.pone.0140480. eCollection 2015.

28.

miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer.

Yanaka Y, Muramatsu T, Uetake H, Kozaki K, Inazawa J.

Carcinogenesis. 2015 Nov;36(11):1363-71. doi: 10.1093/carcin/bgv106. Epub 2015 Aug 11.

PMID:
26264654
29.

The oncogenic role of GASC1 in chemically induced mouse skin cancer.

Ozaki Y, Fujiwara K, Ikeda M, Ozaki T, Terui T, Soma M, Inazawa J, Nagase H.

Mamm Genome. 2015 Dec;26(11-12):591-7. doi: 10.1007/s00335-015-9592-9. Epub 2015 Aug 7.

PMID:
26248577
30.

miR-634 Activates the Mitochondrial Apoptosis Pathway and Enhances Chemotherapy-Induced Cytotoxicity.

Fujiwara N, Inoue J, Kawano T, Tanimoto K, Kozaki K, Inazawa J.

Cancer Res. 2015 Sep 15;75(18):3890-901. doi: 10.1158/0008-5472.CAN-15-0257. Epub 2015 Jul 27.

31.

High Expression of p62 Protein Is Associated with Poor Prognosis and Aggressive Phenotypes in Endometrial Cancer.

Iwadate R, Inoue J, Tsuda H, Takano M, Furuya K, Hirasawa A, Aoki D, Inazawa J.

Am J Pathol. 2015 Sep;185(9):2523-33. doi: 10.1016/j.ajpath.2015.05.008. Epub 2015 Jul 7.

PMID:
26162509
32.

Diverse involvement of isoforms and gene aberrations of Akt in human lung carcinomas.

Dobashi Y, Tsubochi H, Matsubara H, Inoue J, Inazawa J, Endo S, Ooi A.

Cancer Sci. 2015 Jun;106(6):772-81. doi: 10.1111/cas.12669. Epub 2015 May 8.

33.

Identical deletion at 14q13.3 including PAX9 and NKX2-1 in siblings from mosaicism of unaffected parent.

Hayashi S, Yagi M, Morisaki I, Inazawa J.

J Hum Genet. 2015 Apr;60(4):203-6. doi: 10.1038/jhg.2014.123. Epub 2015 Jan 22.

PMID:
25608831
34.

Overexpression of SMYD2 contributes to malignant outcome in gastric cancer.

Komatsu S, Ichikawa D, Hirajima S, Nagata H, Nishimura Y, Kawaguchi T, Miyamae M, Okajima W, Ohashi T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Imoto I, Inazawa J, Otsuji E.

Br J Cancer. 2015 Jan 20;112(2):357-64. doi: 10.1038/bjc.2014.543. Epub 2014 Oct 16.

35.

Chromosome 9q33q34 microdeletion with early infantile epileptic encephalopathy, severe dystonia, abnormal eye movements, and nephroureteral malformations.

Matsumoto H, Zaha K, Nakamura Y, Hayashi S, Inazawa J, Nonoyama S.

Pediatr Neurol. 2014 Jul;51(1):170-5. doi: 10.1016/j.pediatrneurol.2014.03.013. Epub 2014 Apr 4.

PMID:
24938147
36.

Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer.

Hosoda F, Arai Y, Okada N, Shimizu H, Miyamoto M, Kitagawa N, Katai H, Taniguchi H, Yanagihara K, Imoto I, Inazawa J, Ohki M, Shibata T.

Oncogene. 2015 Feb 26;34(9):1196-206. doi: 10.1038/onc.2014.57. Epub 2014 Mar 24.

PMID:
24662817
37.

NF-κB inducing kinase, a central signaling component of the non-canonical pathway of NF-κB, contributes to ovarian cancer progression.

Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, Inazawa J, Yuasa Y, Kubota T, Yamaoka S.

PLoS One. 2014 Feb 12;9(2):e88347. doi: 10.1371/journal.pone.0088347. eCollection 2014.

38.

Genetic variants in C5 and poor response to eculizumab.

Nishimura J, Yamamoto M, Hayashi S, Ohyashiki K, Ando K, Brodsky AL, Noji H, Kitamura K, Eto T, Takahashi T, Masuko M, Matsumoto T, Wano Y, Shichishima T, Shibayama H, Hase M, Li L, Johnson K, Lazarowski A, Tamburini P, Inazawa J, Kinoshita T, Kanakura Y.

N Engl J Med. 2014 Feb 13;370(7):632-9. doi: 10.1056/NEJMoa1311084.

39.

High Expression of SQSTM1/p62 Protein Is Associated with Poor Prognosis in Epithelial Ovarian Cancer.

Iwadate R, Inoue J, Tsuda H, Takano M, Furuya K, Hirasawa A, Aoki D, Inazawa J.

Acta Histochem Cytochem. 2014;47(6):295-301. doi: 10.1267/ahc.14048. Epub 2014 Dec 20.

40.

γ-Glutamylcyclotransferase as a novel immunohistochemical biomarker for the malignancy of esophageal squamous tumors.

Takemura K, Kawachi H, Eishi Y, Kitagaki K, Negi M, Kobayashi M, Uchida K, Inoue J, Inazawa J, Kawano T, Board PG.

Hum Pathol. 2014 Feb;45(2):331-41. doi: 10.1016/j.humpath.2013.09.009. Epub 2013 Oct 3.

PMID:
24342434
41.

Significance of Akt activation and AKT gene increases in soft tissue tumors.

Dobashi Y, Sato E, Oda Y, Inazawa J, Ooi A.

Hum Pathol. 2014 Jan;45(1):127-36. doi: 10.1016/j.humpath.2013.06.024.

PMID:
24321521
42.

The impact of miRNA-based molecular diagnostics and treatment of NRF2-stabilized tumors.

Yamamoto S, Inoue J, Kawano T, Kozaki K, Omura K, Inazawa J.

Mol Cancer Res. 2014 Jan;12(1):58-68. doi: 10.1158/1541-7786.MCR-13-0246-T. Epub 2013 Dec 4.

43.

Genome-wide association study of breast cancer in the Japanese population.

Low SK, Takahashi A, Ashikawa K, Inazawa J, Miki Y, Kubo M, Nakamura Y, Katagiri T.

PLoS One. 2013 Oct 15;8(10):e76463. doi: 10.1371/journal.pone.0076463. eCollection 2013.

44.

Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma.

Yamamoto Y, Konishi H, Ichikawa D, Arita T, Shoda K, Komatsu S, Shiozaki A, Ikoma H, Fujiwara H, Okamoto K, Ochiai T, Inoue J, Inazawa J, Otsuji E.

Oncol Rep. 2013 Oct;30(4):1687-94. doi: 10.3892/or.2013.2606. Epub 2013 Jul 9.

PMID:
23842854
45.

miR-655 Is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2.

Harazono Y, Muramatsu T, Endo H, Uzawa N, Kawano T, Harada K, Inazawa J, Kozaki K.

PLoS One. 2013 May 14;8(5):e62757. doi: 10.1371/journal.pone.0062757. Print 2013.

46.

The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.

Furuta M, Kozaki K, Tanimoto K, Tanaka S, Arii S, Shimamura T, Niida A, Miyano S, Inazawa J.

PLoS One. 2013;8(3):e60155. doi: 10.1371/journal.pone.0060155. Epub 2013 Mar 27.

47.

Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer.

Endo H, Muramatsu T, Furuta M, Uzawa N, Pimkhaokham A, Amagasa T, Inazawa J, Kozaki K.

Carcinogenesis. 2013 Mar;34(3):560-9. doi: 10.1093/carcin/bgs376. Epub 2012 Dec 10.

PMID:
23233740
48.

Esophageal squamous cell carcinoma developed 11 years after allogeneic bone marrow transplantation for acute lymphatic leukemia.

Miyawaki Y, Imoto I, Tokairin Y, Kawada K, Nakajima Y, Nishikage T, Nagai K, Kajiwara M, Inazawa J, Kawano T.

Jpn J Clin Oncol. 2013 Jan;43(1):69-73. doi: 10.1093/jjco/hys184. Epub 2012 Dec 4.

PMID:
23225908
49.

Clinical and radiological features of Japanese patients with a severe phenotype due to CASK mutations.

Takanashi J, Okamoto N, Yamamoto Y, Hayashi S, Arai H, Takahashi Y, Maruyama K, Mizuno S, Shimakawa S, Ono H, Oyanagi R, Kubo S, Barkovich AJ, Inazawa J.

Am J Med Genet A. 2012 Dec;158A(12):3112-8. doi: 10.1002/ajmg.a.35640. Epub 2012 Nov 19.

PMID:
23165780
50.

Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene.

Gaffney CJ, Oka T, Mazack V, Hilman D, Gat U, Muramatsu T, Inazawa J, Golden A, Carey DJ, Farooq A, Tromp G, Sudol M.

Gene. 2012 Nov 10;509(2):215-22. doi: 10.1016/j.gene.2012.08.025. Epub 2012 Aug 24.

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