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Items: 42


Optimization of transdermal deferoxamine leads to enhanced efficacy in healing skin wounds.

Duscher D, Trotsyuk AA, Maan ZN, Kwon SH, Rodrigues M, Engel K, Stern-Buchbinder ZA, Bonham CA, Barrera J, Whittam AJ, Hu MS, Inayathullah M, Rajadas J, Gurtner GC.

J Control Release. 2019 Jul 9;308:232-239. doi: 10.1016/j.jconrel.2019.07.009. [Epub ahead of print]


Fidgetin-Like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing.

O'Rourke BP, Kramer AH, Cao LL, Inayathullah M, Guzik H, Rajadas J, Nosanchuk JD, Sharp DJ.

Adv Wound Care (New Rochelle). 2019 Mar 1;8(3):91-100. doi: 10.1089/wound.2018.0827. Epub 2019 Mar 5.


Characterization of Brain Dysfunction Induced by Bacterial Lipopeptides That Alter Neuronal Activity and Network in Rodent Brains.

Kim KM, Zamaleeva AI, Lee YW, Ahmed MR, Kim E, Lee HR, Pothineni VR, Tao J, Rhee S, Jayakumar M, Inayathullah M, Sivanesan S, Red-Horse K, Palmer TD, Park J, Madison DV, Lee HY, Rajadas J.

J Neurosci. 2018 Dec 12;38(50):10672-10691. doi: 10.1523/JNEUROSCI.0825-17.2018. Epub 2018 Oct 31.


Anti-hyperlipidaemic effects of synthetic analogues of nordihydroguaiaretic acid in dyslipidaemic rats.

Singh M, Bittner S, Li Y, Bittner A, Han L, Cortez Y, Inayathullah M, Arif Z, Parthasarathi R, Rajadas J, Shen WJ, Nicolls MR, Kraemer FB, Azhar S.

Br J Pharmacol. 2019 Feb;176(3):369-385. doi: 10.1111/bph.14528. Epub 2018 Dec 10.


In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease.

Pothineni VR, Parekh MB, Babar MM, Ambati A, Maguire P, Inayathullah M, Kim KM, Tayebi L, Potula HS, Rajadas J.

Drug Des Devel Ther. 2018 Sep 11;12:2915-2921. doi: 10.2147/DDDT.S164966. eCollection 2018.


Cytokines as therapeutic agents and targets in heart disease.

Dubnika A, Manoukian MAC, Mohammadi MR, Parekh MB, Gurjarpadhye AA, Inayathullah M, Dubniks V, Lakey JRT, Rajadas J.

Cytokine Growth Factor Rev. 2018 Oct;43:54-68. doi: 10.1016/j.cytogfr.2018.08.003. Epub 2018 Aug 16. Review.


Deferoxamine can prevent pressure ulcers and accelerate healing in aged mice.

Bonham CA, Rodrigues M, Galvez M, Trotsyuk A, Stern-Buchbinder Z, Inayathullah M, Rajadas J, Gurtner GC.

Wound Repair Regen. 2018 May;26(3):300-305. doi: 10.1111/wrr.12667. Epub 2018 Oct 25.


Controlled Delivery of a Focal Adhesion Kinase Inhibitor Results in Accelerated Wound Closure with Decreased Scar Formation.

Ma K, Kwon SH, Padmanabhan J, Duscher D, Trotsyuk AA, Dong Y, Inayathullah M, Rajadas J, Gurtner GC.

J Invest Dermatol. 2018 Nov;138(11):2452-2460. doi: 10.1016/j.jid.2018.04.034. Epub 2018 Jul 12.


Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptides from a collagen matrix.

Lee AS, Inayathullah M, Lijkwan MA, Zhao X, Sun W, Park S, Hong WX, Parekh MB, Malkovskiy AV, Lau E, Qin X, Pothineni VR, Sanchez-Freire V, Zhang WY, Kooreman NG, Ebert AD, Chan CKF, Nguyen PK, Rajadas J, Wu JC.

Nat Biomed Eng. 2018 Feb;2(2):104-113. doi: 10.1038/s41551-018-0191-4. Epub 2018 Feb 6.


PEG/Dextran Double Layer Influences Fe Ion Release and Colloidal Stability of Iron Oxide Nanoparticles.

Mohammadi MR, Malkovskiy AV, Jothimuthu P, Kim KM, Parekh M, Inayathullah M, Zhuge Y, Rajadas J.

Sci Rep. 2018 Mar 9;8(1):4286. doi: 10.1038/s41598-018-22644-8.


Nordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet-Induced Metabolic Dysfunction in Mice.

Chan JKW, Bittner S, Bittner A, Atwal S, Shen WJ, Inayathullah M, Rajada J, Nicolls MR, Kraemer FB, Azhar S.

J Pharmacol Exp Ther. 2018 May;365(2):281-290. doi: 10.1124/jpet.117.243733. Epub 2018 Feb 22.


Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation.

Hsu JL, Manouvakhova OV, Clemons KV, Inayathullah M, Tu AB, Sobel RA, Tian A, Nazik H, Pothineni VR, Pasupneti S, Jiang X, Dhillon GS, Bedi H, Rajadas J, Haas H, Aurelian L, Stevens DA, Nicolls MR.

Sci Transl Med. 2018 Feb 21;10(429). pii: eaag2616. doi: 10.1126/scitranslmed.aag2616.


Identification of key regions and residues controlling Aβ folding and assembly.

Hayden EY, Hoi KK, Lopez J, Inayathullah M, Condron MM, Teplow DB.

Sci Rep. 2017 Oct 3;7(1):12434. doi: 10.1038/s41598-017-10845-6.


Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.

Hwangbo C, Wu J, Papangeli I, Adachi T, Sharma B, Park S, Zhao L, Ju H, Go GW, Cui G, Inayathullah M, Job JK, Rajadas J, Kwei SL, Li MO, Morrison AR, Quertermous T, Mani A, Red-Horse K, Chun HJ.

Sci Transl Med. 2017 Sep 13;9(407). pii: eaad4000. doi: 10.1126/scitranslmed.aad4000.


Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip.

Jothimuthu P, Hsu JL, Chen R, Inayathullah M, Pothineni VR, Jan A, Gurtner GC, Rajadas J, Nicolls MR.

ChemNanoMat. 2016 Sep;2(9):904-910. Epub 2016 Jul 25.


Screening of NCI-DTP library to identify new drug candidates for Borrelia burgdorferi.

Pothineni VR, Wagh D, Babar MM, Inayathullah M, Watts RE, Kim KM, Parekh MB, Gurjarpadhye AA, Solow-Cordero D, Tayebi L, Rajadas J.

J Antibiot (Tokyo). 2017 Mar;70(3):308-312. doi: 10.1038/ja.2016.131. Epub 2016 Nov 9. No abstract available.


Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment.

Sun W, Lee S, Huang X, Liu S, Inayathullah M, Kim KM, Tang H, Ashford JW, Rajadas J.

Sci Rep. 2016 Oct 6;6:34784. doi: 10.1038/srep34784.


Effect of osmolytes on the conformation and aggregation of some amyloid peptides: CD spectroscopic data.

Inayathullah M, Rajadas J.

Data Brief. 2016 May 4;7:1643-51. doi: 10.1016/j.dib.2016.04.070. eCollection 2016 Jun.


Identification of new drug candidates against Borrelia burgdorferi using high-throughput screening.

Pothineni VR, Wagh D, Babar MM, Inayathullah M, Solow-Cordero D, Kim KM, Samineni AV, Parekh MB, Tayebi L, Rajadas J.

Drug Des Devel Ther. 2016 Apr 1;10:1307-22. doi: 10.2147/DDDT.S101486. eCollection 2016.


Conformational dynamics of a hydrophobic prion fragment (113-127) in different pH and osmolyte solutions.

Inayathullah M, Rajadas J.

Neuropeptides. 2016 Jun;57:9-14. doi: 10.1016/j.npep.2016.02.004. Epub 2016 Feb 18.


Self-assembly and sequence length dependence on nanofibrils of polyglutamine peptides.

Inayathullah M, Tan A, Jeyaraj R, Lam J, Cho NJ, Liu CW, Manoukian MA, Ashkan K, Mahmoudi M, Rajadas J.

Neuropeptides. 2016 Jun;57:71-83. doi: 10.1016/j.npep.2016.01.011. Epub 2016 Feb 3.


Infrared Imaging Tools for Diagnostic Applications in Dermatology.

Gurjarpadhye AA, Parekh MB, Dubnika A, Rajadas J, Inayathullah M.

SM J Clin Med Imaging. 2015;1(1):1-5. Epub 2015 Nov 20.


Transdermal Delivery of Functional Collagen Via Polyvinylpyrrolidone Microneedles.

Sun W, Inayathullah M, Manoukian MA, Malkovskiy AV, Manickam S, Marinkovich MP, Lane AT, Tayebi L, Seifalian AM, Rajadas J.

Ann Biomed Eng. 2015 Dec;43(12):2978-90. doi: 10.1007/s10439-015-1353-0. Epub 2015 Jun 12.


A Thermo-Sensitive Delivery Platform for Topical Administration of Inflammatory Bowel Disease Therapies.

Sinha SR, Nguyen LP, Inayathullah M, Malkovskiy A, Habte F, Rajadas J, Habtezion A.

Gastroenterology. 2015 Jul;149(1):52-55.e2. doi: 10.1053/j.gastro.2015.04.002. Epub 2015 Apr 8.


Borreliacidal activity of Borrelia metal transporter A (BmtA) binding small molecules by manganese transport inhibition.

Wagh D, Pothineni VR, Inayathullah M, Liu S, Kim KM, Rajadas J.

Drug Des Devel Ther. 2015 Feb 11;9:805-16. doi: 10.2147/DDDT.S77063. eCollection 2015.


Recent Developments in Diffusion Tensor Imaging of Brain.

Parekh MB, Gurjarpadhye AA, Manoukian MA, Dubnika A, Rajadas J, Inayathullah M.

Radiol Open J. 2015;1(1):1-12. Epub 2015 Dec 11.


Transdermal deferoxamine prevents pressure-induced diabetic ulcers.

Duscher D, Neofytou E, Wong VW, Maan ZN, Rennert RC, Inayathullah M, Januszyk M, Rodrigues M, Malkovskiy AV, Whitmore AJ, Walmsley GG, Galvez MG, Whittam AJ, Brownlee M, Rajadas J, Gurtner GC.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):94-9. doi: 10.1073/pnas.1413445112. Epub 2014 Dec 22.


Polymeric Nanoparticles to Combat Squamous Cell Carcinomas in Patients with Dystrophic Epidermolysis Bullosa.

Manoukian MAC, Ott SV, Rajadas J, Inayathullah M.

Recent Pat Nanomed. 2014;4(1):15-24.


[Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction.

Serpooshan V, Sivanesan S, Huang X, Mahmoudi M, Malkovskiy AV, Zhao M, Inayathullah M, Wagh D, Zhang XJ, Metzler S, Bernstein D, Wu JC, Ruiz-Lozano P, Rajadas J.

Biomaterials. 2015 Jan;37:289-98. doi: 10.1016/j.biomaterials.2014.08.045. Epub 2014 Oct 13.


Solvent microenvironments and copper binding alters the conformation and toxicity of a prion fragment.

Inayathullah M, Satheeshkumar KS, Malkovskiy AV, Carre AL, Sivanesan S, Hardesty JO, Rajadas J.

PLoS One. 2013 Dec 27;8(12):e85160. doi: 10.1371/journal.pone.0085160. eCollection 2013.


Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.

Tian W, Jiang X, Tamosiuniene R, Sung YK, Qian J, Dhillon G, Gera L, Farkas L, Rabinovitch M, Zamanian RT, Inayathullah M, Fridlib M, Rajadas J, Peters-Golden M, Voelkel NF, Nicolls MR.

Sci Transl Med. 2013 Aug 28;5(200):200ra117. doi: 10.1126/scitranslmed.3006674.


Polyvinylpyrrolidone microneedles enable delivery of intact proteins for diagnostic and therapeutic applications.

Sun W, Araci Z, Inayathullah M, Manickam S, Zhang X, Bruce MA, Marinkovich MP, Lane AT, Milla C, Rajadas J, Butte MJ.

Acta Biomater. 2013 Aug;9(8):7767-74. doi: 10.1016/j.actbio.2013.04.045. Epub 2013 May 3.


Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42).

Rajadas J, Sun W, Li H, Inayathullah M, Cereghetti D, Tan A, de Mello Coelho V, Chrest FJ, Kusiak JW, Smith WW, Taub D, Wu JC, Rifkind JM.

PLoS One. 2013;8(3):e58194. doi: 10.1371/journal.pone.0058194. Epub 2013 Mar 7.


Pullulan hydrogels improve mesenchymal stem cell delivery into high-oxidative-stress wounds.

Wong VW, Rustad KC, Glotzbach JP, Sorkin M, Inayathullah M, Major MR, Longaker MT, Rajadas J, Gurtner GC.

Macromol Biosci. 2011 Nov 10;11(11):1458-66. doi: 10.1002/mabi.201100180. Epub 2011 Oct 12.


Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solution.

Rajadas J, Liu CW, Novick P, Kelley NW, Inayathullah M, Lemieux MC, Pande VS.

PLoS One. 2011;6(7):e21776. doi: 10.1371/journal.pone.0021776. Epub 2011 Jul 22.


Structural dynamics of the ΔE22 (Osaka) familial Alzheimer's disease-linked amyloid β-protein.

Inayathullah M, Teplow DB.

Amyloid. 2011 Sep;18(3):98-107. doi: 10.3109/13506129.2011.580399. Epub 2011 Jun 13.


Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid.

Dey D, Inayathullah M, Lee AS, LeMieux MC, Zhang X, Wu Y, Nag D, De Almeida PE, Han L, Rajadas J, Wu JC.

Biomaterials. 2011 Jul;32(20):4647-58. doi: 10.1016/j.biomaterials.2011.03.016. Epub 2011 Apr 8.


Glucose oxidase incorporated collagen matrices for dermal wound repair in diabetic rat models: a biochemical study.

Arul V, Masilamoni JG, Jesudason EP, Jaji PJ, Inayathullah M, Dicky John DG, Vignesh S, Jayakumar R.

J Biomater Appl. 2012 May;26(8):917-38. doi: 10.1177/0885328210390402. Epub 2011 Mar 1.


Amino acid position-specific contributions to amyloid beta-protein oligomerization.

Maji SK, Ogorzalek Loo RR, Inayathullah M, Spring SM, Vollers SS, Condron MM, Bitan G, Loo JA, Teplow DB.

J Biol Chem. 2009 Aug 28;284(35):23580-91. doi: 10.1074/jbc.M109.038133. Epub 2009 Jun 30.


Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy.

Zaghi J, Goldenson B, Inayathullah M, Lossinsky AS, Masoumi A, Avagyan H, Mahanian M, Bernas M, Weinand M, Rosenthal MJ, Espinosa-Jeffrey A, de Vellis J, Teplow DB, Fiala M.

Acta Neuropathol. 2009 Feb;117(2):111-24. doi: 10.1007/s00401-008-0481-0. Epub 2009 Jan 13.


Amyloid beta-protein assembly as a therapeutic target of Alzheimer's disease.

Yamin G, Ono K, Inayathullah M, Teplow DB.

Curr Pharm Des. 2008;14(30):3231-46. Review.


Synthesis, pharmacological screening, quantum chemical and in vitro permeability studies of N-Mannich bases of benzimidazoles through bovine cornea.

Jesudason EP, Sridhar SK, Malar EJ, Shanmugapandiyan P, Inayathullah M, Arul V, Selvaraj D, Jayakumar R.

Eur J Med Chem. 2009 May;44(5):2307-12. doi: 10.1016/j.ejmech.2008.03.043. Epub 2008 Apr 11.


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