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Items: 1 to 50 of 63

1.

Kir Channel Blockages by Proflavine Derivatives via Multiple Modes of Interaction.

Inanobe A, Itamochi H, Kurachi Y.

Mol Pharmacol. 2018 Jun;93(6):592-600. doi: 10.1124/mol.117.111377. Epub 2018 Apr 12.

PMID:
29650538
2.

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes.

Kinboshi M, Mukai T, Nagao Y, Matsuba Y, Tsuji Y, Tanaka S, Tokudome K, Shimizu S, Ito H, Ikeda A, Inanobe A, Kurachi Y, Inoue S, Ohno Y.

Front Mol Neurosci. 2017 Dec 7;10:408. doi: 10.3389/fnmol.2017.00408. eCollection 2017.

3.

Isolation of proflavine as a blocker of G protein-gated inward rectifier potassium channels by a cell growth-based screening system.

Kawada H, Inanobe A, Kurachi Y.

Neuropharmacology. 2016 Oct;109:18-28. doi: 10.1016/j.neuropharm.2016.05.016. Epub 2016 May 26.

PMID:
27236080
4.

An Epithelial Ca2+-Sensor Protein is an Alternative to Calmodulin to Compose Functional KCNQ1 Channels.

Inanobe A, Tsuzuki C, Kurachi Y.

Cell Physiol Biochem. 2015;36(5):1847-61.

5.

Clustering of Kir4.1 at specialized compartments of the lateral membrane in ependymal cells of rat brain.

Fujita A, Inanobe A, Hibino H, Nielsen S, Ottersen OP, Kurachi Y.

Cell Tissue Res. 2015 Feb;359(2):627-634. doi: 10.1007/s00441-014-2030-6. Epub 2014 Nov 8.

PMID:
25380566
6.

RGS4 regulates partial agonism of the M2 muscarinic receptor-activated K+ currents.

Chen IS, Furutani K, Inanobe A, Kurachi Y.

J Physiol. 2014 Mar 15;592(6):1237-48. doi: 10.1113/jphysiol.2013.269803. Epub 2014 Jan 13.

7.

Conformational changes underlying pore dilation in the cytoplasmic domain of mammalian inward rectifier K+ channels.

Inanobe A, Nakagawa A, Kurachi Y.

PLoS One. 2013 Nov 11;8(11):e79844. doi: 10.1371/journal.pone.0079844. eCollection 2013.

8.

Short-term desensitization of muscarinic K+ current in the heart.

Murakami S, Inanobe A, Kurachi Y.

Biophys J. 2013 Sep 17;105(6):1515-25. doi: 10.1016/j.bpj.2013.08.009.

9.

Membrane channels as integrators of G-protein-mediated signaling.

Inanobe A, Kurachi Y.

Biochim Biophys Acta. 2014 Feb;1838(2):521-31. doi: 10.1016/j.bbamem.2013.08.018. Epub 2013 Sep 9. Review.

10.

Pharmacophore modeling for hERG channel facilitation.

Yamakawa Y, Furutani K, Inanobe A, Ohno Y, Kurachi Y.

Biochem Biophys Res Commun. 2012 Feb 3;418(1):161-6. doi: 10.1016/j.bbrc.2011.12.153. Epub 2012 Jan 8.

PMID:
22244872
11.

A mechanism underlying compound-induced voltage shift in the current activation of hERG by antiarrhythmic agents.

Furutani K, Yamakawa Y, Inanobe A, Iwata M, Ohno Y, Kurachi Y.

Biochem Biophys Res Commun. 2011 Nov 11;415(1):141-6. doi: 10.1016/j.bbrc.2011.10.034. Epub 2011 Oct 12.

PMID:
22020101
12.

Interactions of cations with the cytoplasmic pores of inward rectifier K(+) channels in the closed state.

Inanobe A, Nakagawa A, Kurachi Y.

J Biol Chem. 2011 Dec 2;286(48):41801-11. doi: 10.1074/jbc.M111.278531. Epub 2011 Oct 9.

13.

Inverse agonist-like action of cadmium on G-protein-gated inward-rectifier K(+) channels.

Inanobe A, Matsuura T, Nakagawa A, Kurachi Y.

Biochem Biophys Res Commun. 2011 Apr 8;407(2):366-71. doi: 10.1016/j.bbrc.2011.03.025. Epub 2011 Mar 17.

PMID:
21396912
14.

A structural determinant for the control of PIP2 sensitivity in G protein-gated inward rectifier K+ channels.

Inanobe A, Nakagawa A, Matsuura T, Kurachi Y.

J Biol Chem. 2010 Dec 3;285(49):38517-23. doi: 10.1074/jbc.M110.161703. Epub 2010 Sep 29.

15.

Cellular modelling: experiments and simulation to develop a physiological model of G-protein control of muscarinic K+ channels in mammalian atrial cells.

Murakami S, Suzuki S, Ishii M, Inanobe A, Kurachi Y.

Philos Trans A Math Phys Eng Sci. 2010 Jun 28;368(1921):2983-3000. doi: 10.1098/rsta.2010.0093.

16.

Inwardly rectifying potassium channels: their structure, function, and physiological roles.

Hibino H, Inanobe A, Furutani K, Murakami S, Findlay I, Kurachi Y.

Physiol Rev. 2010 Jan;90(1):291-366. doi: 10.1152/physrev.00021.2009. Review.

17.

Mutational and in silico analyses for antidepressant block of astroglial inward-rectifier Kir4.1 channel.

Furutani K, Ohno Y, Inanobe A, Hibino H, Kurachi Y.

Mol Pharmacol. 2009 Jun;75(6):1287-95. doi: 10.1124/mol.108.052936. Epub 2009 Mar 5. Erratum in: Mol Pharmacol. 2009 Aug;76(2):451.

18.

In silico prediction of the chemical block of human ether-a-go-go-related gene (hERG) K+ current.

Inanobe A, Kamiya N, Murakami S, Fukunishi Y, Nakamura H, Kurachi Y.

J Physiol Sci. 2008 Dec;58(7):459-70. doi: 10.2170/physiolsci.RV-0114-08-07-R1. Epub 2008 Nov 27.

PMID:
19032804
19.

Mutational analysis of block and facilitation of HERG current by a class III anti-arrhythmic agent, nifekalant.

Hosaka Y, Iwata M, Kamiya N, Yamada M, Kinoshita K, Fukunishi Y, Tsujimae K, Hibino H, Aizawa Y, Inanobe A, Nakamura H, Kurachi Y.

Channels (Austin). 2007 May-Jun;1(3):198-208. Epub 2007 Jul 6.

PMID:
18690032
20.

Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors.

Ohno Y, Hibino H, Lossin C, Inanobe A, Kurachi Y.

Brain Res. 2007 Oct 31;1178:44-51. Epub 2007 Aug 16.

PMID:
17920044
21.

Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.

Inanobe A, Matsuura T, Nakagawa A, Kurachi Y.

Channels (Austin). 2007 Jan-Feb;1(1):39-45. Epub 2007 Jan 16.

PMID:
19151589
22.

Inhibition of astroglial inwardly rectifying Kir4.1 channels by a tricyclic antidepressant, nortriptyline.

Su S, Ohno Y, Lossin C, Hibino H, Inanobe A, Kurachi Y.

J Pharmacol Exp Ther. 2007 Feb;320(2):573-80. Epub 2006 Oct 27.

23.

Mechanism of partial agonist action at the NR1 subunit of NMDA receptors.

Inanobe A, Furukawa H, Gouaux E.

Neuron. 2005 Jul 7;47(1):71-84.

24.

Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina.

Ishii M, Fujita A, Iwai K, Kusaka S, Higashi K, Inanobe A, Hibino H, Kurachi Y.

Am J Physiol Cell Physiol. 2003 Aug;285(2):C260-7. Epub 2003 Apr 9.

25.

An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.

Saito H, Kimura M, Inanobe A, Ohe T, Kurachi Y.

Biochem Biophys Res Commun. 2002 Aug 23;296(3):523-9.

PMID:
12176012
26.

Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses.

Inanobe A, Fujita A, Ito M, Tomoike H, Inageda K, Kurachi Y.

Am J Physiol Cell Physiol. 2002 Jun;282(6):C1396-403.

27.
28.

Ca(2+) elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart.

Ishii M, Inanobe A, Fujita S, Makino Y, Hosoya Y, Kurachi Y.

Circ Res. 2001 Nov 23;89(11):1045-50.

PMID:
11717162
29.

Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel.

Inanobe A, Fujita S, Makino Y, Matsushita K, Ishii M, Chachin M, Kurachi Y.

J Physiol. 2001 Aug 15;535(Pt 1):133-43.

30.

An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain.

Higashi K, Fujita A, Inanobe A, Tanemoto M, Doi K, Kubo T, Kurachi Y.

Am J Physiol Cell Physiol. 2001 Sep;281(3):C922-31.

32.

Functional Kir7.1 channels localized at the root of apical processes in rat retinal pigment epithelium.

Kusaka S, Inanobe A, Fujita A, Makino Y, Tanemoto M, Matsushita K, Tano Y, Kurachi Y.

J Physiol. 2001 Feb 15;531(Pt 1):27-36.

33.

C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels.

Matsuoka T, Matsushita K, Katayama Y, Fujita A, Inageda K, Tanemoto M, Inanobe A, Yamashita S, Matsuzawa Y, Kurachi Y.

Circ Res. 2000 Nov 10;87(10):873-80.

PMID:
11073882
34.

A regulator of G protein signalling (RGS) protein confers agonist-dependent relaxation gating to a G protein-gated K+ channel.

Fujita S, Inanobe A, Chachin M, Aizawa Y, Kurachi Y.

J Physiol. 2000 Jul 15;526 Pt 2:341-7.

35.

In vivo formation of a proton-sensitive K+ channel by heteromeric subunit assembly of Kir5.1 with Kir4.1.

Tanemoto M, Kittaka N, Inanobe A, Kurachi Y.

J Physiol. 2000 Jun 15;525 Pt 3:587-92.

36.

Anchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domain.

Hibino H, Inanobe A, Tanemoto M, Fujita A, Doi K, Kubo T, Hata Y, Takai Y, Kurachi Y.

EMBO J. 2000 Jan 4;19(1):78-83.

37.

Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis.

Inanobe A, Horio Y, Fujita A, Tanemoto M, Hibino H, Inageda K, Kurachi Y.

J Physiol. 1999 Nov 15;521 Pt 1:19-30.

38.

Expression and polarized distribution of an inwardly rectifying K+ channel, Kir4.1, in rat retinal pigment epithelium.

Kusaka S, Horio Y, Fujita A, Matsushita K, Inanobe A, Gotow T, Uchiyama Y, Tano Y, Kurachi Y.

J Physiol. 1999 Oct 15;520 Pt 2:373-81.

39.

Expression of an inwardly rectifying K(+) channel, Kir4.1, in satellite cells of rat cochlear ganglia.

Hibino H, Horio Y, Fujita A, Inanobe A, Doi K, Gotow T, Uchiyama Y, Kubo T, Kurachi Y.

Am J Physiol. 1999 Oct;277(4 Pt 1):C638-44.

PMID:
10516093
40.
41.

Secretagogue-induced exocytosis recruits G protein-gated K+ channels to plasma membrane in endocrine cells.

Morishige K, Inanobe A, Yoshimoto Y, Kurachi H, Murata Y, Tokunaga Y, Maeda T, Maruyama Y, Kurachi Y.

J Biol Chem. 1999 Mar 19;274(12):7969-74.

42.

Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel.

Yoshimoto Y, Fukuyama Y, Horio Y, Inanobe A, Gotoh M, Kurachi Y.

FEBS Lett. 1999 Feb 12;444(2-3):265-9.

43.

Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.

Inanobe A, Yoshimoto Y, Horio Y, Morishige KI, Hibino H, Matsumoto S, Tokunaga Y, Maeda T, Hata Y, Takai Y, Kurachi Y.

J Neurosci. 1999 Feb 1;19(3):1006-17.

44.

G protein regulation of potassium ion channels.

Yamada M, Inanobe A, Kurachi Y.

Pharmacol Rev. 1998 Dec;50(4):723-60. Review. No abstract available.

45.

A novel junction-like membrane complex in the optic nerve astrocyte of the Japanese macaque with a possible relation to a potassium ion channel.

Yakushigawa H, Tokunaga Y, Inanobe A, Kani K, Kurachi Y, Maeda T.

Anat Rec. 1998 Apr;250(4):465-74.

PMID:
9566537
46.

Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals.

Ishii M, Horio Y, Tada Y, Hibino H, Inanobe A, Ito M, Yamada M, Gotow T, Uchiyama Y, Kurachi Y.

J Neurosci. 1997 Oct 15;17(20):7725-35.

47.
48.

Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90.

Horio Y, Hibino H, Inanobe A, Yamada M, Ishii M, Tada Y, Satoh E, Hata Y, Takai Y, Kurachi Y.

J Biol Chem. 1997 May 16;272(20):12885-8.

49.

Immunolocalization of an inwardly rectifying K+ channel, K(AB)-2 (Kir4.1), in the basolateral membrane of renal distal tubular epithelia.

Ito M, Inanobe A, Horio Y, Hibino H, Isomoto S, Ito H, Mori K, Tonosaki A, Tomoike H, Kurachi Y.

FEBS Lett. 1996 Jun 10;388(1):11-5.

50.

G protein-gated K+ channel (GIRK1) protein is expressed presynaptically in the paraventricular nucleus of the hypothalamus.

Morishige KI, Inanobe A, Takahashi N, Yoshimoto Y, Kurachi H, Miyake A, Tokunaga Y, Maeda T, Kurachi Y.

Biochem Biophys Res Commun. 1996 Mar 18;220(2):300-5.

PMID:
8645300

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